melatonin has been researched along with Alcohol Abuse in 24 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| " The present study was performed in order to establish whether alcoholism modifies the effects of melatonin (MEL) on the neuroendocrine control of growth hormone (GH) secretion." | 7.70 | Alcoholism abolishes the effects of melatonin on growth hormone secretion in humans. ( Coiro, V; Vescovi, PP, 1998) |
| "The melatonin data were correlated with the suppressive effects of dexamethasone (DXT) on cortisol secretion evaluated both during alcohol intake and during abstinence." | 5.28 | Urine melatonin in alcoholic patients: a marker of alcohol abuse? ( Bo, P; Costelli, P; Filippi, U; Fonzi, S; Murialdo, G; Polleri, A; Savoldi, F, 1991) |
| "In this secondary analysis of a pilot clinical trial with individuals with alcohol and nicotine use disorders, we investigate the relationship between serum concentrations of oxytocin, β-endorphin, melatonin, α-melanocyte-stimulating hormone, substance P, and orexin, with objective biomarkers (salivary cotinine and serum γ-glutamyl transferase [GGT]) as well as with self-reported smoking and alcohol drinking." | 4.02 | Brief Report: Relationship Between Cotinine Levels and Peripheral Endogenous Concentrations of Oxytocin, β-Endorphin, and Orexin in Individuals With Both Alcohol and Nicotine Use Disorders. ( Brown, ZE; Haass-Koffler, CL; Kurtis, J; Lee, MR; Leggio, L; Perciballi, R; Swift, RM; Zywiak, WH, 2021) |
| " The present study was performed in order to establish whether alcoholism modifies the effects of melatonin (MEL) on the neuroendocrine control of growth hormone (GH) secretion." | 3.70 | Alcoholism abolishes the effects of melatonin on growth hormone secretion in humans. ( Coiro, V; Vescovi, PP, 1998) |
| " The dosage of melaxen ranged from 3 to 6 mg depending on the respond to the minimal dose." | 2.78 | [An open-label non-comparative study of the efficacy and safety of melaxen in treatment of sleep disorders in alcohol dependent patients during the period of abstinence]. ( Andreeva, NE; Andrianov, FV; Anipchenko, AV; Eryshev, OF, 2013) |
| "Melatonin is a hormone mainly secreted by the pineal gland during the dark phase of the light-dark cycle." | 2.41 | [Melatonin. I. Physiology of its secretion]. ( Bruls, E; Crasson, M; Legros, JJ, 2000) |
| "The melatonin data were correlated with the suppressive effects of dexamethasone (DXT) on cortisol secretion evaluated both during alcohol intake and during abstinence." | 1.28 | Urine melatonin in alcoholic patients: a marker of alcohol abuse? ( Bo, P; Costelli, P; Filippi, U; Fonzi, S; Murialdo, G; Polleri, A; Savoldi, F, 1991) |
| "Melatonin treatment also resulted in reducing daily total fluid intake as well as ethanol consumption in light-deprived hamsters." | 1.26 | Pineal gland and melatonin influence on chronic alcohol consumption by hamsters. ( Rudeen, PK; Symmes, SK, 1981) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (20.83) | 18.7374 |
| 1990's | 4 (16.67) | 18.2507 |
| 2000's | 4 (16.67) | 29.6817 |
| 2010's | 4 (16.67) | 24.3611 |
| 2020's | 7 (29.17) | 2.80 |
| Authors | Studies |
|---|---|
| Borisova, AB | 1 |
| Veltishchev, DY | 1 |
| Lisitsyna, TA | 1 |
| Reshetnyak, TM | 1 |
| Seravina, OF | 1 |
| Kovalevskaya, OB | 1 |
| Cheldieva, FA | 1 |
| Abramkin, AA | 1 |
| Bokhan, NA | 1 |
| Roshchina, OV | 1 |
| Simutkin, GG | 1 |
| Levchuk, LA | 1 |
| Ivanova, SA | 1 |
| Osler, M | 1 |
| Jørgensen, MB | 1 |
| Meyrel, M | 1 |
| Rolland, B | 1 |
| Geoffroy, PA | 1 |
| Gendy, MNS | 1 |
| Lagzdins, D | 1 |
| Schaman, J | 1 |
| Le Foll, B | 1 |
| Haass-Koffler, CL | 1 |
| Perciballi, R | 1 |
| Brown, ZE | 1 |
| Lee, MR | 1 |
| Zywiak, WH | 1 |
| Kurtis, J | 1 |
| Swift, RM | 1 |
| Leggio, L | 1 |
| Roehrs, TA | 1 |
| Auciello, J | 1 |
| Tseng, J | 1 |
| Whiteside, G | 1 |
| Kurhaluk, N | 1 |
| Chuffa, LG | 1 |
| Seiva, FR | 1 |
| Fávaro, WJ | 1 |
| Amorim, JP | 1 |
| Teixeira, GR | 1 |
| Mendes, LO | 1 |
| Fioruci-Fontanelli, BA | 1 |
| Pinheiro, PF | 1 |
| Martinez, M | 1 |
| Martinez, FE | 1 |
| Eryshev, OF | 1 |
| Anipchenko, AV | 1 |
| Andreeva, NE | 1 |
| Andrianov, FV | 1 |
| Peres, R | 1 |
| do Amaral, FG | 1 |
| Madrigrano, TC | 1 |
| Scialfa, JH | 1 |
| Bordin, S | 1 |
| Afeche, SC | 1 |
| Cipolla-Neto, J | 1 |
| Conroy, DA | 1 |
| Hairston, IS | 1 |
| Arnedt, JT | 1 |
| Hoffmann, RF | 1 |
| Armitage, R | 1 |
| Brower, KJ | 1 |
| Kühlwein, E | 1 |
| Hauger, RL | 1 |
| Irwin, MR | 1 |
| Borisov, MM | 1 |
| Rudeen, PK | 1 |
| Symmes, SK | 1 |
| Schmitz, MM | 1 |
| Sepandj, A | 1 |
| Pichler, PM | 1 |
| Rudas, S | 1 |
| Coiro, V | 1 |
| Vescovi, PP | 1 |
| Bruls, E | 1 |
| Crasson, M | 1 |
| Legros, JJ | 1 |
| Roehrs, T | 1 |
| Roth, T | 1 |
| Danel, T | 1 |
| Touitou, Y | 1 |
| Wetterberg, L | 1 |
| Aperia, B | 1 |
| Gorelick, DA | 1 |
| Gwirtzman, HE | 1 |
| McGuire, MT | 1 |
| Serafetinides, EA | 1 |
| Yuwiler, A | 1 |
| Murialdo, G | 1 |
| Filippi, U | 1 |
| Costelli, P | 1 |
| Fonzi, S | 1 |
| Bo, P | 1 |
| Polleri, A | 1 |
| Savoldi, F | 1 |
| Veit, I | 1 |
| Dietzel, M | 1 |
| Lesch, OM | 1 |
| Hermann, P | 1 |
| Birsak, L | 1 |
| Reschenhofer, E | 1 |
| Majumdar, SK | 1 |
| Miles, A | 1 |
| Moss, HB | 1 |
| Tamarkin, L | 1 |
| Majchrowicz, E | 1 |
| Martin, PR | 1 |
| Linnoila, M | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Placebo-controlled, Double -Blind Randomised Trial of Suvorexant in the Management Comorbid Sleep Disorder and Alcohol Dependence[NCT03897062] | Phase 2 | 22 participants (Actual) | Interventional | 2019-08-26 | Terminated (stopped due to Recruitment problems during covid lockdowns resulted in Merck ceasing supply of suvorexant/placebo) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
7 reviews available for melatonin and Alcohol Abuse
| Article | Year |
|---|---|
Alterations in circadian rhythms following alcohol use: A systematic review.
Topics: Alcohol Drinking; Alcoholism; Body Temperature; Circadian Rhythm; Dose-Response Relationship, Drug; | 2020 |
Current and potential pharmacological treatment options for insomnia in patients with alcohol use disorder in recovery.
Topics: Alcohol Abstinence; Alcoholism; Anticonvulsants; Antidepressive Agents; Antipsychotic Agents; Humans | 2020 |
Alcohol and melatonin.
Topics: Alcoholism; Antioxidants; Circadian Rhythm; Ethanol; Humans; Melatonin | 2021 |
[Role of the serotoninergic structures of the brain in alcoholism].
Topics: Acetaldehyde; Alcoholism; Animals; Brain; Brain Chemistry; Carbolines; Cricetinae; Ethanol; Humans; | 1981 |
[Melatonin. I. Physiology of its secretion].
Topics: Alcoholism; Body Constitution; Circadian Rhythm; Cushing Syndrome; Electromagnetic Fields; Female; H | 2000 |
Sleep, sleepiness, and alcohol use.
Topics: Alcohol Drinking; Alcoholism; Animals; Dose-Response Relationship, Drug; Ethanol; Humans; Melatonin; | 2001 |
[Alcohol, chronobiology and sleep].
Topics: Alcoholism; Animals; Chronobiology Disorders; Ethanol; Humans; Melatonin; Sleep Wake Disorders | 2001 |
2 trials available for melatonin and Alcohol Abuse
| Article | Year |
|---|---|
Melatonin for Treatment-Seeking Alcohol Use Disorder patients with sleeping problems: A randomized clinical pilot trial.
Topics: Adult; Aged; Alcoholism; Double-Blind Method; Drug Administration Schedule; Female; Humans; Male; Me | 2020 |
[An open-label non-comparative study of the efficacy and safety of melaxen in treatment of sleep disorders in alcohol dependent patients during the period of abstinence].
Topics: Administration, Oral; Adult; Alcoholism; Antioxidants; Cognitive Behavioral Therapy; Dose-Response R | 2013 |
15 other studies available for melatonin and Alcohol Abuse
| Article | Year |
|---|---|
Topics: Adolescent; Adult; Aged; Alcoholism; Anhedonia; Antiphospholipid Syndrome; Anxiety; Comorbidity; Dep | 2022 |
Association of benzodiazepines, Z-drugs, pregabalin, and melatonin with traffic accidents: A nationwide cohort and case-crossover study in Danish adults.
Topics: Accidents, Traffic; Adolescent; Adult; Aged; Alcoholism; Benzodiazepines; Chlordiazepoxide; Cohort S | 2022 |
Brief Report: Relationship Between Cotinine Levels and Peripheral Endogenous Concentrations of Oxytocin, β-Endorphin, and Orexin in Individuals With Both Alcohol and Nicotine Use Disorders.
Topics: Adult; Alcohol Drinking; Alcoholism; alpha-MSH; beta-Endorphin; Cotinine; Female; gamma-Glutamyltran | 2021 |
Melatonin and ethanol intake exert opposite effects on circulating estradiol and progesterone and differentially regulate sex steroid receptors in the ovaries, oviducts, and uteri of adult rats.
Topics: Alcoholism; Animals; Estradiol; Ethanol; Female; Melatonin; Ovary; Oviducts; Progesterone; Rats; Rec | 2013 |
Ethanol consumption and pineal melatonin daily profile in rats.
Topics: Acetylserotonin O-Methyltransferase; Alcoholism; Animals; Arylalkylamine N-Acetyltransferase; Circad | 2011 |
Dim light melatonin onset in alcohol-dependent men and women compared with healthy controls.
Topics: Adult; Aged; Alcohol Drinking; Alcoholism; Case-Control Studies; Female; Humans; Light; Male; Melato | 2012 |
Abnormal nocturnal melatonin secretion and disordered sleep in abstinent alcoholics.
Topics: Adult; Alcohol Drinking; Alcoholism; Body Mass Index; Case-Control Studies; Electroencephalography; | 2003 |
Pineal gland and melatonin influence on chronic alcohol consumption by hamsters.
Topics: Alcoholism; Animals; Choice Behavior; Cricetinae; Humans; Male; Melatonin; Mesocricetus; Photic Stim | 1981 |
Disrupted melatonin-secretion during alcohol withdrawal.
Topics: Adult; Alcoholism; Biological Clocks; Female; Humans; Male; Melatonin; Middle Aged; Substance Withdr | 1996 |
Alcoholism abolishes the effects of melatonin on growth hormone secretion in humans.
Topics: Adult; Alcoholism; Human Growth Hormone; Humans; Hypoglycemia; Insulin; Kinetics; Male; Melatonin; M | 1998 |
Age, alcoholism and depression are associated with low levels of urinary melatonin.
Topics: Adult; Age Factors; Alcoholism; Depressive Disorder; Female; Humans; Male; Melatonin; Middle Aged; P | 1992 |
Urine melatonin in alcoholic patients: a marker of alcohol abuse?
Topics: Adult; Alcoholism; Analysis of Variance; Circadian Rhythm; Dexamethasone; Humans; Hydrocortisone; Ma | 1991 |
[Circadian neuroendocrinologic profile in patients with multiple drug abuse].
Topics: Adult; Alcoholism; Circadian Rhythm; Female; Gonadotropins, Pituitary; Hormones; Humans; Hydrocortis | 1986 |
Disturbed melatonin secretion in chronic alcoholism and withdrawal.
Topics: Adult; Alcoholism; Ethanol; Humans; Male; Melatonin; Middle Aged; Substance Withdrawal Syndrome | 1987 |
Pineal function during ethanol intoxication, dependence, and withdrawal.
Topics: Alcohol Withdrawal Delirium; Alcoholism; Analysis of Variance; Animals; Circadian Rhythm; Male; Mela | 1986 |