Page last updated: 2024-10-19

melatonin and Adenoma Sebaceum

melatonin has been researched along with Adenoma Sebaceum in 4 studies

Adenoma Sebaceum: Facial ANGIOFIBROMA in tuberous sclerosis

Research Excerpts

ExcerptRelevanceReference
"To determine normal melatonin excretion patterns in healthy children without sleep disorder and to compare these with those of patients with tuberous sclerosis complex and sleep disorder responsive to exogenous melatonin, we measured 6-sulfatoxymelatonin excretion in 21 healthy children and in 7 patients with tuberous sclerosis complex and sleep disorder responsive to melatonin (a 5 mg oral dose increasing total sleep time)."9.11Melatonin excretion in normal children and in tuberous sclerosis complex with sleep disorder responsive to melatonin. ( English, J; Hancock, E; O'Callaghan, F; Osborne, JP, 2005)
"We report a randomized, double-blind, controlled, crossover trial investigating the response to oral melatonin using two dose regimens in patients with sleep disorders associated with tuberous sclerosis complex."9.11Effect of melatonin dosage on sleep disorder in tuberous sclerosis complex. ( Hancock, E; O'Callaghan, F; Osborne, JP, 2005)
"The results of a therapeutic trial of the use of melatonin in patients with tuberous sclerosis complex who also have severe sleep problems are reported."9.09Use of melatonin to treat sleep disorders in tuberous sclerosis. ( Clarke, AA; Hancock, E; Hunt, A; O'Callaghan, FJ; Osborne, JP, 1999)
"To determine normal melatonin excretion patterns in healthy children without sleep disorder and to compare these with those of patients with tuberous sclerosis complex and sleep disorder responsive to exogenous melatonin, we measured 6-sulfatoxymelatonin excretion in 21 healthy children and in 7 patients with tuberous sclerosis complex and sleep disorder responsive to melatonin (a 5 mg oral dose increasing total sleep time)."5.11Melatonin excretion in normal children and in tuberous sclerosis complex with sleep disorder responsive to melatonin. ( English, J; Hancock, E; O'Callaghan, F; Osborne, JP, 2005)
"We report a randomized, double-blind, controlled, crossover trial investigating the response to oral melatonin using two dose regimens in patients with sleep disorders associated with tuberous sclerosis complex."5.11Effect of melatonin dosage on sleep disorder in tuberous sclerosis complex. ( Hancock, E; O'Callaghan, F; Osborne, JP, 2005)
"The results of a therapeutic trial of the use of melatonin in patients with tuberous sclerosis complex who also have severe sleep problems are reported."5.09Use of melatonin to treat sleep disorders in tuberous sclerosis. ( Clarke, AA; Hancock, E; Hunt, A; O'Callaghan, FJ; Osborne, JP, 1999)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (25.00)18.2507
2000's3 (75.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Braam, W1
Smits, MG1
Didden, R1
Korzilius, H1
Van Geijlswijk, IM1
Curfs, LM1
Hancock, E3
O'Callaghan, F2
English, J1
Osborne, JP3
O'Callaghan, FJ1
Clarke, AA1
Hunt, A1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Controlled-Release Melatonin (Melatonin CR)for the Treatment of Impaired Sleep Maintenance (ISM) in 4-8 Year Old Children With Autism Spectrum Disorders (ASD).[NCT01033565]Phase 41 participants (Actual)Interventional2010-03-04Terminated (stopped due to Unsuccessful in recruiting appropriate subjects.)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Clinical Global Impression-Improvement

Assigns numerical score indicating level of improvement compared to baseline. Scale is rated from 1-7: 1= very much improved; 2= much improved; 3= minimally improved; 4= no change; 5= minimally worse; 6= much worse; 7= very much worse. (NCT01033565)
Timeframe: 2 weeks

Interventionunits on a scale (Number)
Natrol2

Reviews

1 review available for melatonin and Adenoma Sebaceum

ArticleYear
Exogenous melatonin for sleep problems in individuals with intellectual disability: a meta-analysis.
    Developmental medicine and child neurology, 2009, Volume: 51, Issue:5

    Topics: Angelman Syndrome; Central Nervous System Depressants; Child; Child Development Disorders, Pervasive

2009

Trials

3 trials available for melatonin and Adenoma Sebaceum

ArticleYear
Melatonin excretion in normal children and in tuberous sclerosis complex with sleep disorder responsive to melatonin.
    Journal of child neurology, 2005, Volume: 20, Issue:1

    Topics: Administration, Oral; Adolescent; Antioxidants; Case-Control Studies; Child; Child, Preschool; Circa

2005
Effect of melatonin dosage on sleep disorder in tuberous sclerosis complex.
    Journal of child neurology, 2005, Volume: 20, Issue:1

    Topics: Administration, Oral; Adult; Antioxidants; Child; Child, Preschool; Cross-Over Studies; Dose-Respons

2005
Use of melatonin to treat sleep disorders in tuberous sclerosis.
    Developmental medicine and child neurology, 1999, Volume: 41, Issue:2

    Topics: Adolescent; Adult; Child, Preschool; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Bl

1999