melatonin has been researched along with Adenocarcinoma in 58 studies
Adenocarcinoma: A malignant epithelial tumor with a glandular organization.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Patients with stage IIIB or IV lung adenocarcinoma, who had progressed after prior standard chemotherapy, and with an Eastern Cooperative Oncology Group PS > or = 2, received a daily combination of somatostatin, retinoids, melatonin, vitamin D, bromocriptine, and cyclophosphamide." | 9.12 | Somatostatin, retinoids, melatonin, vitamin D, bromocriptine, and cyclophosphamide in chemotherapy-pretreated patients with advanced lung adenocarcinoma and low performance status. ( Martino, V; Norsa, A, 2007) |
| "The aim of this study was to determine the effects of some polyunsaturated fatty acids plus phytomelatonin from walnuts in the development of mammary gland adenocarcinoma." | 7.81 | Synergistic anti-tumor effects of melatonin and PUFAs from walnuts in a murine mammary adenocarcinoma model. ( Berra, MA; Comba, A; Das, UN; Eynard, AR; Garcia, CP; Labuckas, DO; Lamarque, AL; Pasqualini, ME; Silva, RA, 2015) |
| "In this study, the effects of melatonin or beta-glucan treatments on tumor growth, pro-oxidant, and antioxidant status in tumor tissue were investigated in Dunning 3327 MatLyLu prostatic adenocarcinoma model." | 7.77 | Melatonin and beta-glucan alone or in combination inhibit the growth of dunning prostatic adenocarcinoma. ( Balkan, J; Doğru-Abbasoğlu, S; Kabasakal, L; Keyer-Uysal, M; Sener, G; Uysal, M, 2011) |
| " The breast cancer cells were incubated for 2 days in the presence of melatonin, CGP 52608 (at concentrations of 10(-5)M, 10(-7)M, 10(-9)M, 10-(11)M ) and methotrexate (at concentrations of 0." | 7.73 | Growth-inhibitory action of melatonin and thiazolidinedione derivative CGP 52608 on murine 16/C breast cancer cells. ( Karasek, M; Kunert-Radek, J; Lawnicka, H; Pawlikowski, M; Winczyk, K, 2006) |
| "Melatonin inhibits the proliferation of estrogen receptor alpha (ERalpha)-positive (MCF-7), but not ERalpha-negative (MDA-MB-231) breast cancer cells." | 7.71 | MT(1) melatonin receptor overexpression enhances the growth suppressive effect of melatonin in human breast cancer cells. ( Collins, AR; Dai, J; Dubocovich, ML; Hill, SM; Yuan, L, 2002) |
| "Previous studies on human breast cancer patients showed a decline in circulating melatonin levels corresponding to primary tumor growth and an increase when relapse occurred." | 7.70 | Serial transplants of DMBA-induced mammary tumors in Fischer rats as a model system for human breast cancer. VI. The role of different forms of tumor-associated stress for the regulation of pineal melatonin secretion. ( Bartsch, C; Bartsch, H; Besenthal, I; Buchberger, A; Effenberger-Klein, A; Kruse-Jarres, JD; Mecke, D; Rokos, H; Stieglitz, A, 1999) |
| "Highly differentiated endometrial adenocarcinoma is described in which the cells of the APUD-system (apudocytes) producing melatonin, noradrenaline and chorionic gonadotropin are detected histochemically and immunohistochemically." | 7.67 | [Polyfunctional endometrial adenocarcinoma producing melatonin, noradrenaline and chorionic gonadotropin]. ( Kvetnoĭ, IM; Rodkina, RA; Stoliarova, ES, 1985) |
| "The effects of the pineal indole melatonin on a transplantable androgen-insensitive fast-growing rat prostatic adenocarcinoma, the Dunning R 3327 HIF tumor, were examined." | 7.67 | Studies on the effects of the pineal hormone melatonin on an androgen-insensitive rat prostatic adenocarcinoma, the Dunning R 3327 HIF tumor. ( Buzzell, GR, 1988) |
| "Melatonin is a tryptophan-derived molecule with pleiotropic activities which is produced in all living organisms." | 6.58 | Melatonin in Prevention of the Sequence from Reflux Esophagitis to Barrett's Esophagus and Esophageal Adenocarcinoma: Experimental and Clinical Perspectives. ( Brzozowska, I; Brzozowski, T; Kwiecien, S; Magierowska, K; Magierowski, M; Majka, J; Szlachcic, A; Wierdak, M; Wojcik, D; Zagajewski, J, 2018) |
| "Laboratory study was via cultured endometrial cancer cells." | 5.72 | Melatonin Inhibits 17β-Estradiol-Induced Epithelial-Mesenchymal Transition in Endometrial Adenocarcinoma Cells via Upregulating Numb Expression. ( Li, C; Li, M; Liu, Z; Qi, S; Zhang, H; Zhao, X, 2022) |
| "Melatonin has antitumor activity via several mechanisms including its anti-proliferative and pro-apoptotic effects." | 5.48 | Melatonin increases the effect of 5-fluorouracil-based chemotherapy in human colorectal adenocarcinoma cells in vitro. ( Bejarano, I; Espino, J; Pariente, JA; Pariente, R; Rodríguez, AB, 2018) |
| "Melatonin treatment also influenced the expression of HDAC-related molecules (HDAC1 and Ac-histone H3), upregulated the apoptosis-related molecules (PUMA and Bax), and downregulated the proliferation-related molecule (PCNA) and the anti-apoptosis-related molecule (Bcl2)." | 5.42 | HDAC1 inhibition by melatonin leads to suppression of lung adenocarcinoma cells via induction of oxidative stress and activation of apoptotic pathways. ( Di, S; Fan, C; Jiang, S; Li, T; Li, W; Li, X; Ma, Z; Pan, Y; Reiter, RJ; Yan, X; Yang, Y; Zhang, Z, 2015) |
| "Melatonin was tested on the cell line only after 24 h incubation (direct effect), and on the co-culture system of SK-LU-1 and PBMC to investigate any indirect effect." | 5.40 | Immunomodulatory effect of melatonin in SK-LU-1 human lung adenocarcinoma cells co-cultured with peripheral blood mononuclear cells. ( Barusrux, S; Johns, NP; Khamphio, M; Plaimee, P; Weerapreeyakul, N, 2014) |
| "Polycystic kidney disease is common in this transgenic line." | 5.32 | The effect of melatonin treatment regimen on mammary adenocarcinoma development in HER-2/neu transgenic mice. ( Alimova, IN; Anisimov, VN; Baturin, DA; Manton, KG; Popovich, IG; Semenchenko, AV; Yashin, AI; Zabezhinski, MA, 2003) |
| "Conventional antiandrogen therapy for prostatic cancer generally results in the death of androgen-dependent cells, resulting in shrinkage of the tumor, followed by regrowth of the tumor as androgen-insensitive cells take over." | 5.27 | Effects of olfactory bulbectomy, melatonin, and/or pinealectomy on three sublines of the Dunning R3327 rat prostatic adenocarcinoma. ( Amerongen, HM; Buzzell, GR; Hennes, SC; McBlain, WA; O'Brien, MG; Toma, JG, 1987) |
| "Patients with stage IIIB or IV lung adenocarcinoma, who had progressed after prior standard chemotherapy, and with an Eastern Cooperative Oncology Group PS > or = 2, received a daily combination of somatostatin, retinoids, melatonin, vitamin D, bromocriptine, and cyclophosphamide." | 5.12 | Somatostatin, retinoids, melatonin, vitamin D, bromocriptine, and cyclophosphamide in chemotherapy-pretreated patients with advanced lung adenocarcinoma and low performance status. ( Martino, V; Norsa, A, 2007) |
| "Hydrogen-rich water has a significant protective effect on OGD/R-causing HT22 cell injury, and the mechanism may be related to the inhibition of autophagy." | 4.40 | Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19. ( , 2023) |
| "Through activation of the ERK pathway, nicotine, in both normal MCF-10A and low-malignant breast cancer cells (MCF7), promotes increased motility and invasiveness." | 3.88 | Increase in motility and invasiveness of MCF7 cancer cells induced by nicotine is abolished by melatonin through inhibition of ERK phosphorylation. ( Bizzarri, M; Catizone, A; Cucina, A; Dinicola, S; Fabrizi, G; Masiello, MG; Minini, M; Proietti, S; Reiter, RJ; Ricci, G; Verna, R, 2018) |
| "The aim of this study was to determine the effects of some polyunsaturated fatty acids plus phytomelatonin from walnuts in the development of mammary gland adenocarcinoma." | 3.81 | Synergistic anti-tumor effects of melatonin and PUFAs from walnuts in a murine mammary adenocarcinoma model. ( Berra, MA; Comba, A; Das, UN; Eynard, AR; Garcia, CP; Labuckas, DO; Lamarque, AL; Pasqualini, ME; Silva, RA, 2015) |
| " In this study, we evaluated the effect of melatonin on the genotoxic activity of irinotecan in healthy human lymphocytes and a lung cancer cell line (A549) and a colorectal adenocarcinoma cell line (HT29) in vitro." | 3.79 | The modulatory effect of melatonin on genotoxicity of irinotecan in healthy human lymphocytes and cancer cells. ( Kontek, R; Nowicka, H, 2013) |
| "In this study, the effects of melatonin or beta-glucan treatments on tumor growth, pro-oxidant, and antioxidant status in tumor tissue were investigated in Dunning 3327 MatLyLu prostatic adenocarcinoma model." | 3.77 | Melatonin and beta-glucan alone or in combination inhibit the growth of dunning prostatic adenocarcinoma. ( Balkan, J; Doğru-Abbasoğlu, S; Kabasakal, L; Keyer-Uysal, M; Sener, G; Uysal, M, 2011) |
| " The breast cancer cells were incubated for 2 days in the presence of melatonin, CGP 52608 (at concentrations of 10(-5)M, 10(-7)M, 10(-9)M, 10-(11)M ) and methotrexate (at concentrations of 0." | 3.73 | Growth-inhibitory action of melatonin and thiazolidinedione derivative CGP 52608 on murine 16/C breast cancer cells. ( Karasek, M; Kunert-Radek, J; Lawnicka, H; Pawlikowski, M; Winczyk, K, 2006) |
| "In order to assess whether light exposure at night influences the growth of mammary tumors, as well as the role of melatonin in this process, female rats bearing DMBA-induced mammary adenocarcinomas were exposed to different lighting environments." | 3.73 | Exposure to light-at-night increases the growth of DMBA-induced mammary adenocarcinomas in rats. ( Alonso-González, C; Cos, S; González, A; Martínez-Campa, C; Mediavilla, D; Sánchez-Barceló, EJ, 2006) |
| "Melatonin inhibits the proliferation of estrogen receptor alpha (ERalpha)-positive (MCF-7), but not ERalpha-negative (MDA-MB-231) breast cancer cells." | 3.71 | MT(1) melatonin receptor overexpression enhances the growth suppressive effect of melatonin in human breast cancer cells. ( Collins, AR; Dai, J; Dubocovich, ML; Hill, SM; Yuan, L, 2002) |
| "Previous studies on human breast cancer patients showed a decline in circulating melatonin levels corresponding to primary tumor growth and an increase when relapse occurred." | 3.70 | Serial transplants of DMBA-induced mammary tumors in Fischer rats as a model system for human breast cancer. VI. The role of different forms of tumor-associated stress for the regulation of pineal melatonin secretion. ( Bartsch, C; Bartsch, H; Besenthal, I; Buchberger, A; Effenberger-Klein, A; Kruse-Jarres, JD; Mecke, D; Rokos, H; Stieglitz, A, 1999) |
| " injections of 1,2-dimethylhydrazine (DMH) at a single dose of 21 mg/kg of body weight." | 3.69 | Melatonin and colon carcinogenesis: I. Inhibitory effect of melatonin on development of intestinal tumors induced by 1,2-dimethylhydrazine in rats. ( Anisimov, VN; Popovich, IG; Zabezhinski, MA, 1997) |
| "The effects of the pineal indole melatonin on a transplantable androgen-insensitive fast-growing rat prostatic adenocarcinoma, the Dunning R 3327 HIF tumor, were examined." | 3.67 | Studies on the effects of the pineal hormone melatonin on an androgen-insensitive rat prostatic adenocarcinoma, the Dunning R 3327 HIF tumor. ( Buzzell, GR, 1988) |
| "Injections of the pineal hormone melatonin reduced growth and increased doubling time of the R3327H Dunning prostatic adenocarcinoma in the Copenhagen X Fisher rat." | 3.67 | Inhibition of Dunning tumor growth by melatonin. ( Berkowitz, AS; Philo, R, 1988) |
| "Highly differentiated endometrial adenocarcinoma is described in which the cells of the APUD-system (apudocytes) producing melatonin, noradrenaline and chorionic gonadotropin are detected histochemically and immunohistochemically." | 3.67 | [Polyfunctional endometrial adenocarcinoma producing melatonin, noradrenaline and chorionic gonadotropin]. ( Kvetnoĭ, IM; Rodkina, RA; Stoliarova, ES, 1985) |
| "The effects of the pineal hormone, melatonin, and of pinealectomy on the incidence of mammary adenocarcinoma in Sprague-Dawley rats treated with 7,12-dimethylbenz(alpha)-anthracene (DMBA) were investigated." | 3.66 | Melatonin inhibition and pinealectomy enhancement of 7,12-dimethylbenz(a)anthracene-induced mammary tumors in the rat. ( Chabner, B; Cohen, M; Lippman, M; Reichert, C; Roselle, D; Tamarkin, L, 1981) |
| "Melatonin is a tryptophan-derived molecule with pleiotropic activities which is produced in all living organisms." | 2.58 | Melatonin in Prevention of the Sequence from Reflux Esophagitis to Barrett's Esophagus and Esophageal Adenocarcinoma: Experimental and Clinical Perspectives. ( Brzozowska, I; Brzozowski, T; Kwiecien, S; Magierowska, K; Magierowski, M; Majka, J; Szlachcic, A; Wierdak, M; Wojcik, D; Zagajewski, J, 2018) |
| "Laboratory study was via cultured endometrial cancer cells." | 1.72 | Melatonin Inhibits 17β-Estradiol-Induced Epithelial-Mesenchymal Transition in Endometrial Adenocarcinoma Cells via Upregulating Numb Expression. ( Li, C; Li, M; Liu, Z; Qi, S; Zhang, H; Zhao, X, 2022) |
| "Melatonin has antitumor activity via several mechanisms including its anti-proliferative and pro-apoptotic effects." | 1.48 | Melatonin increases the effect of 5-fluorouracil-based chemotherapy in human colorectal adenocarcinoma cells in vitro. ( Bejarano, I; Espino, J; Pariente, JA; Pariente, R; Rodríguez, AB, 2018) |
| "Treatment of prostate cancer (PCa), a leading cause of cancer among males, lacks successful strategies especially in advanced, hormone-refractory stages." | 1.46 | IGFBP3 and MAPK/ERK signaling mediates melatonin-induced antitumor activity in prostate cancer. ( Cepas, V; Gonzalez-Menendez, P; Gonzalez-Pola, I; Hevia, D; Mayo, JC; Quiros-Gonzalez, I; Rodriguez-Garcia, A; Sainz, RM, 2017) |
| "Melatonin treatment also influenced the expression of HDAC-related molecules (HDAC1 and Ac-histone H3), upregulated the apoptosis-related molecules (PUMA and Bax), and downregulated the proliferation-related molecule (PCNA) and the anti-apoptosis-related molecule (Bcl2)." | 1.42 | HDAC1 inhibition by melatonin leads to suppression of lung adenocarcinoma cells via induction of oxidative stress and activation of apoptotic pathways. ( Di, S; Fan, C; Jiang, S; Li, T; Li, W; Li, X; Ma, Z; Pan, Y; Reiter, RJ; Yan, X; Yang, Y; Zhang, Z, 2015) |
| "Treatment with melatonin prior to irradiation did not produce any significant change in apoptosis." | 1.40 | CCAR2 deficiency augments genotoxic stress-induced apoptosis in the presence of melatonin in non-small cell lung cancer cells. ( Jeong, JW; Kim, JE; Kim, W, 2014) |
| "Melatonin was tested on the cell line only after 24 h incubation (direct effect), and on the co-culture system of SK-LU-1 and PBMC to investigate any indirect effect." | 1.40 | Immunomodulatory effect of melatonin in SK-LU-1 human lung adenocarcinoma cells co-cultured with peripheral blood mononuclear cells. ( Barusrux, S; Johns, NP; Khamphio, M; Plaimee, P; Weerapreeyakul, N, 2014) |
| "When capecitabine and melatonin were combined, a well-differentiated pancreatic adenocarcinoma was observed in 10% of animals." | 1.37 | Improvement of capecitabine antitumoral activity by melatonin in pancreatic cancer. ( Arjona, A; Montilla, P; Muntané, J; Padillo, J; Perea, D; Ruiz-Rabelo, J; Túnez, I; Vázquez, R, 2011) |
| "The treatment metformin alone inhibited the growth of transplantable HER2 mammary carcinoma in FVB/N male mice by 46% at the 45(th) day after transplantation (p < 0." | 1.36 | Metformin extends life span of HER-2/neu transgenic mice and in combination with melatonin inhibits growth of transplantable tumors in vivo. ( Anikin, IV; Anisimov, VN; Egormin, PA; Karkach, AS; Piskunova, TS; Popovich, IG; Romanyukha, AA; Tyndyk, ML; Yurova, MN; Zabezhinski, MA, 2010) |
| "Polycystic kidney disease is common in this transgenic line." | 1.32 | The effect of melatonin treatment regimen on mammary adenocarcinoma development in HER-2/neu transgenic mice. ( Alimova, IN; Anisimov, VN; Baturin, DA; Manton, KG; Popovich, IG; Semenchenko, AV; Yashin, AI; Zabezhinski, MA, 2003) |
| "The effect of melatonin on endometrial cancer cell growth was investigated using two cell lines, SNG-II and Ishikawa, which are different in their estrogen receptor status." | 1.31 | Differential growth inhibitory effect of melatonin on two endometrial cancer cell lines. ( Ishizuka, B; Kanishi, Y; Kobayashi, Y; Noda, S; Saito, K, 2000) |
| "Melatonin was also shown to inhibit carcinogenesis in the small intestine." | 1.29 | [Effect of melatonin on 1,2-dimethylhydrazine-induced intestinal tumors in rats]. ( Anisimov, VN; Muratov, EI; Popovich, IG, 1996) |
| "Melatonin was given intramuscularly at a daily dose of 20 mg at 3." | 1.28 | Endocrine and immune effects of melatonin therapy in metastatic cancer patients. ( Barni, S; Crispino, S; Fraschini, F; Lissoni, P; Tancini, G, 1989) |
| "Conventional antiandrogen therapy for prostatic cancer generally results in the death of androgen-dependent cells, resulting in shrinkage of the tumor, followed by regrowth of the tumor as androgen-insensitive cells take over." | 1.27 | Effects of olfactory bulbectomy, melatonin, and/or pinealectomy on three sublines of the Dunning R3327 rat prostatic adenocarcinoma. ( Amerongen, HM; Buzzell, GR; Hennes, SC; McBlain, WA; O'Brien, MG; Toma, JG, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (12.07) | 18.7374 |
| 1990's | 9 (15.52) | 18.2507 |
| 2000's | 17 (29.31) | 29.6817 |
| 2010's | 20 (34.48) | 24.3611 |
| 2020's | 5 (8.62) | 2.80 |
| Authors | Studies |
|---|---|
| Zhang, H | 1 |
| Qi, S | 1 |
| Liu, Z | 1 |
| Li, C | 1 |
| Li, M | 1 |
| Zhao, X | 1 |
| Sun, Q | 1 |
| Zhang, J | 1 |
| Li, X | 2 |
| Yang, G | 1 |
| Cheng, S | 1 |
| Guo, D | 1 |
| Zhang, Q | 1 |
| Sun, F | 1 |
| Zhao, F | 1 |
| Yang, D | 1 |
| Wang, S | 1 |
| Wang, T | 1 |
| Liu, S | 1 |
| Zou, L | 1 |
| Zhang, Y | 1 |
| Liu, H | 1 |
| Das, M | 1 |
| Haldar, C | 1 |
| Yadav, SK | 1 |
| Oshiba, RT | 1 |
| Touson, E | 1 |
| Elsherbini, YM | 1 |
| Abdraboh, ME | 1 |
| Pariente, R | 1 |
| Bejarano, I | 1 |
| Rodríguez, AB | 1 |
| Pariente, JA | 1 |
| Espino, J | 1 |
| Proietti, S | 1 |
| Catizone, A | 1 |
| Masiello, MG | 1 |
| Dinicola, S | 1 |
| Fabrizi, G | 1 |
| Minini, M | 1 |
| Ricci, G | 1 |
| Verna, R | 1 |
| Reiter, RJ | 2 |
| Cucina, A | 1 |
| Bizzarri, M | 1 |
| Majka, J | 1 |
| Wierdak, M | 1 |
| Brzozowska, I | 1 |
| Magierowski, M | 1 |
| Szlachcic, A | 1 |
| Wojcik, D | 1 |
| Kwiecien, S | 1 |
| Magierowska, K | 1 |
| Zagajewski, J | 1 |
| Brzozowski, T | 1 |
| Dznelashvili, NO | 1 |
| Kasradze, DG | 1 |
| Tavartkiladze, AG | 1 |
| Mariamidze, AG | 1 |
| Dzhinchveladze, DN | 1 |
| Zhou, Q | 3 |
| Gui, S | 2 |
| Wang, Y | 2 |
| Plaimee, P | 3 |
| Khamphio, M | 1 |
| Weerapreeyakul, N | 3 |
| Barusrux, S | 3 |
| Johns, NP | 2 |
| Kim, W | 1 |
| Jeong, JW | 1 |
| Kim, JE | 1 |
| Thumanu, K | 1 |
| Tanthanuch, W | 1 |
| Garcia, CP | 1 |
| Lamarque, AL | 1 |
| Comba, A | 1 |
| Berra, MA | 1 |
| Silva, RA | 1 |
| Labuckas, DO | 1 |
| Das, UN | 1 |
| Eynard, AR | 1 |
| Pasqualini, ME | 1 |
| Fan, C | 1 |
| Pan, Y | 1 |
| Yang, Y | 1 |
| Di, S | 1 |
| Jiang, S | 1 |
| Ma, Z | 1 |
| Li, T | 1 |
| Zhang, Z | 1 |
| Li, W | 1 |
| Yan, X | 1 |
| Mayo, JC | 1 |
| Hevia, D | 1 |
| Quiros-Gonzalez, I | 1 |
| Rodriguez-Garcia, A | 1 |
| Gonzalez-Menendez, P | 1 |
| Cepas, V | 1 |
| Gonzalez-Pola, I | 1 |
| Sainz, RM | 1 |
| Kniaz'kin, IV | 1 |
| Panchenko, AV | 1 |
| Petrishchev, NN | 1 |
| Kvetnoĭ, IM | 3 |
| Anisimov, VN | 6 |
| Tanaka, T | 2 |
| Yasui, Y | 1 |
| Tanaka, M | 1 |
| Oyama, T | 1 |
| Rahman, KM | 1 |
| Egormin, PA | 1 |
| Piskunova, TS | 1 |
| Popovich, IG | 5 |
| Tyndyk, ML | 1 |
| Yurova, MN | 1 |
| Zabezhinski, MA | 4 |
| Anikin, IV | 1 |
| Karkach, AS | 1 |
| Romanyukha, AA | 1 |
| Jung-Hynes, B | 1 |
| Schmit, TL | 1 |
| Reagan-Shaw, SR | 1 |
| Siddiqui, IA | 1 |
| Mukhtar, H | 1 |
| Ahmad, N | 1 |
| Ruiz-Rabelo, J | 1 |
| Vázquez, R | 1 |
| Arjona, A | 1 |
| Perea, D | 1 |
| Montilla, P | 1 |
| Túnez, I | 1 |
| Muntané, J | 1 |
| Padillo, J | 1 |
| Zhang, S | 1 |
| Zuo, L | 1 |
| Wei, W | 1 |
| Mazzoccoli, G | 2 |
| Sothern, RB | 1 |
| Pazienza, V | 1 |
| Piepoli, A | 1 |
| Muscarella, LA | 1 |
| Giuliani, F | 1 |
| Tarquini, R | 2 |
| Kabasakal, L | 1 |
| Sener, G | 1 |
| Balkan, J | 1 |
| Doğru-Abbasoğlu, S | 1 |
| Keyer-Uysal, M | 1 |
| Uysal, M | 1 |
| Durfort, T | 1 |
| Francois, JC | 1 |
| Kontek, R | 1 |
| Nowicka, H | 1 |
| Alimova, IN | 1 |
| Baturin, DA | 1 |
| Manton, KG | 1 |
| Semenchenko, AV | 1 |
| Yashin, AI | 1 |
| Cos, S | 1 |
| Mediavilla, D | 1 |
| Martínez-Campa, C | 1 |
| González, A | 1 |
| Alonso-González, C | 1 |
| Sánchez-Barceló, EJ | 1 |
| Lenoir, V | 1 |
| de Jonage-Canonico, MB | 1 |
| Perrin, MH | 1 |
| Martin, A | 1 |
| Scholler, R | 1 |
| Kerdelhué, B | 1 |
| Winczyk, K | 1 |
| Lawnicka, H | 1 |
| Pawlikowski, M | 1 |
| Kunert-Radek, J | 1 |
| Karasek, M | 2 |
| Norsa, A | 1 |
| Martino, V | 1 |
| Tamarkin, L | 1 |
| Cohen, M | 1 |
| Roselle, D | 1 |
| Reichert, C | 1 |
| Lippman, M | 1 |
| Chabner, B | 1 |
| Liburdy, RP | 1 |
| Sloma, TR | 1 |
| Sokolic, R | 1 |
| Yaswen, P | 1 |
| Muratov, EI | 1 |
| Bartsch, C | 3 |
| Kvetnoy, I | 1 |
| Kvetnaia, T | 1 |
| Bartsch, H | 3 |
| Molotkov, A | 1 |
| Franz, H | 1 |
| Raikhlin, N | 1 |
| Mecke, D | 3 |
| Buchberger, A | 1 |
| Stieglitz, A | 1 |
| Effenberger-Klein, A | 1 |
| Kruse-Jarres, JD | 1 |
| Besenthal, I | 1 |
| Rokos, H | 1 |
| Petranka, J | 1 |
| Baldwin, W | 1 |
| Biermann, J | 1 |
| Jayadev, S | 1 |
| Barrett, JC | 1 |
| Murphy, E | 1 |
| Thun-Battersby, S | 1 |
| Mevissen, M | 1 |
| Löscher, W | 1 |
| Shtylik, AV | 1 |
| Ben-Huh, H | 1 |
| Gurevich, P | 1 |
| Berman, V | 1 |
| Tendler, Y | 1 |
| Zusman, I | 1 |
| Teplitzky, SR | 2 |
| Blask, DE | 3 |
| Cheng, Q | 2 |
| Myers, L | 2 |
| Hill, SM | 3 |
| Kanishi, Y | 1 |
| Kobayashi, Y | 1 |
| Noda, S | 1 |
| Ishizuka, B | 1 |
| Saito, K | 1 |
| Kozlova, IV | 1 |
| Osadchuk, MA | 1 |
| Kvetnaia, TV | 1 |
| Popuchiev, VV | 1 |
| Szadowska, A | 1 |
| Geppert, M | 1 |
| Xi, SC | 1 |
| Tam, PC | 1 |
| Brown, GM | 1 |
| Pang, SF | 1 |
| Shiu, SY | 1 |
| Scott, AE | 1 |
| Cosma, GN | 1 |
| Frank, AA | 1 |
| Wells, RL | 1 |
| Gardner, HS | 1 |
| Kiefer, TL | 1 |
| Dwivedi, PD | 1 |
| Moroz, K | 1 |
| Anderson, MB | 1 |
| Collins, A | 1 |
| Dai, J | 2 |
| Yuan, L | 2 |
| Spriggs, LL | 1 |
| Kos-Kudla, B | 1 |
| Ostrowska, Z | 1 |
| Kozlowski, A | 1 |
| Marek, B | 1 |
| Ciesielska-Kopacz, N | 1 |
| Kudla, M | 1 |
| Kajdaniuk, D | 1 |
| Strzelczyk, J | 1 |
| Staszewicz, P | 1 |
| Collins, AR | 1 |
| Dubocovich, ML | 1 |
| Lemus-Wilson, AM | 1 |
| Wilson, ST | 1 |
| Lissoni, P | 1 |
| Barni, S | 1 |
| Crispino, S | 1 |
| Tancini, G | 1 |
| Fraschini, F | 1 |
| Philo, R | 1 |
| Berkowitz, AS | 1 |
| Buzzell, GR | 2 |
| Toma, JG | 1 |
| Amerongen, HM | 1 |
| Hennes, SC | 1 |
| O'Brien, MG | 1 |
| McBlain, WA | 1 |
| Rodkina, RA | 1 |
| Stoliarova, ES | 1 |
| Hamilton, T | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Pilot, Open-label Study to Evaluate the Effects of a Prostate Health Formulation on Scores Attained From the International Prostate Symptom Score (I-PSS) Questionnaire Among Overall Healthy Male Participants Who Report Lower Urinary Tract Complaints[NCT02886832] | 30 participants (Anticipated) | Interventional | 2016-09-21 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 reviews available for melatonin and Adenocarcinoma
| Article | Year |
|---|---|
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp | 2023 |
Melatonin in Prevention of the Sequence from Reflux Esophagitis to Barrett's Esophagus and Esophageal Adenocarcinoma: Experimental and Clinical Perspectives.
Topics: Adenocarcinoma; Animals; Barrett Esophagus; Esophageal Neoplasms; Esophagitis, Peptic; Esophagus; Hu | 2018 |
Breast cancer: a model system for studying the neuroendocrine role of pineal melatonin in oncology.
Topics: Adenocarcinoma; Animals; Breast Neoplasms; Cell Cycle; Cell Line; Female; Humans; Mammary Neoplasms, | 1992 |
2 trials available for melatonin and Adenocarcinoma
| Article | Year |
|---|---|
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp | 2023 |
Somatostatin, retinoids, melatonin, vitamin D, bromocriptine, and cyclophosphamide in chemotherapy-pretreated patients with advanced lung adenocarcinoma and low performance status.
Topics: Adenocarcinoma; Adult; Aged; Bromocriptine; Cyclophosphamide; Drug Therapy, Combination; Female; Hum | 2007 |
54 other studies available for melatonin and Adenocarcinoma
| Article | Year |
|---|---|
Melatonin Inhibits 17β-Estradiol-Induced Epithelial-Mesenchymal Transition in Endometrial Adenocarcinoma Cells via Upregulating Numb Expression.
Topics: Adenocarcinoma; Cell Line, Tumor; Cell Proliferation; Endometrial Neoplasms; Epithelial-Mesenchymal | 2022 |
The ubiquitin-specific protease 8 antagonizes melatonin-induced endocytic degradation of MT
Topics: Adenocarcinoma; Adenocarcinoma of Lung; Animals; Humans; Lung Neoplasms; Melatonin; Receptor, Melato | 2022 |
Shift and longtime light induces endometrioid adenocarcinoma via activation of PKC-α/Akt pathway in female golden hamster: Involvement of altered Aanat and Bmal1 rhythm.
Topics: Adenocarcinoma; Animals; Carcinoma, Endometrioid; Circadian Rhythm; Cricetinae; Female; Humans; Mela | 2023 |
Melatonin: A regulator of the interplay between FoxO1, miR96, and miR215 signaling to diminish the growth, survival, and metastasis of murine adenocarcinoma.
Topics: Adenocarcinoma; Animals; Antioxidants; Apoptosis; Forkhead Box Protein O1; Melatonin; Mice; MicroRNA | 2021 |
Melatonin increases the effect of 5-fluorouracil-based chemotherapy in human colorectal adenocarcinoma cells in vitro.
Topics: Adenocarcinoma; Cell Line, Tumor; Colorectal Neoplasms; Fluorouracil; Humans; Melatonin | 2018 |
Increase in motility and invasiveness of MCF7 cancer cells induced by nicotine is abolished by melatonin through inhibition of ERK phosphorylation.
Topics: Adenocarcinoma; Breast Neoplasms; Cell Movement; Humans; MAP Kinase Signaling System; MCF-7 Cells; M | 2018 |
[Expression of epidermal growth factor receptor and plasmatic level of melatonin in simple and complex endometrial hyperplasia].
Topics: Adenocarcinoma; Endometrial Hyperplasia; Endometrium; ErbB Receptors; Female; Gene Expression Regula | 2013 |
Melatonin inhibits the migration of human lung adenocarcinoma A549 cell lines involving JNK/MAPK pathway.
Topics: Adenocarcinoma; Adenocarcinoma of Lung; Antineoplastic Agents; Antioxidants; Cell Line, Tumor; Cell | 2014 |
Immunomodulatory effect of melatonin in SK-LU-1 human lung adenocarcinoma cells co-cultured with peripheral blood mononuclear cells.
Topics: Adenocarcinoma; Adenocarcinoma of Lung; Antineoplastic Agents; Antioxidants; Apoptosis; Cell Line, T | 2014 |
CCAR2 deficiency augments genotoxic stress-induced apoptosis in the presence of melatonin in non-small cell lung cancer cells.
Topics: Adaptor Proteins, Signal Transducing; Adenocarcinoma; Antioxidants; Apoptosis; Blotting, Western; Ca | 2014 |
Melatonin induces apoptosis through biomolecular changes, in SK-LU-1 human lung adenocarcinoma cells.
Topics: Adenocarcinoma; Apoptosis; Caspase 3; Caspase 7; Cell Line, Tumor; DNA Fragmentation; Humans; Lung N | 2014 |
Melatonin potentiates cisplatin-induced apoptosis and cell cycle arrest in human lung adenocarcinoma cells.
Topics: Adenocarcinoma; Adenocarcinoma of Lung; Antineoplastic Agents; Apoptosis; Cell Cycle Checkpoints; Ce | 2015 |
Synergistic anti-tumor effects of melatonin and PUFAs from walnuts in a murine mammary adenocarcinoma model.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Breast Neoplasms; Cyclooxygen | 2015 |
HDAC1 inhibition by melatonin leads to suppression of lung adenocarcinoma cells via induction of oxidative stress and activation of apoptotic pathways.
Topics: Adenocarcinoma; Adenocarcinoma of Lung; Apoptosis; Cell Line, Tumor; Cell Survival; Glutathione; His | 2015 |
IGFBP3 and MAPK/ERK signaling mediates melatonin-induced antitumor activity in prostate cancer.
Topics: Adenocarcinoma; Animals; Cell Differentiation; Cell Line, Tumor; Disease Models, Animal; Enzyme-Link | 2017 |
[Melatonin, aging and tumors of the prostate].
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Aging; Humans; Immunohistochemistry; Male; Melatonin | 2008 |
[Colon carcinogenesis in rat vs. variable light].
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Animals; Antioxidants; Carcinogens; Cell Differentiation; Cel | 2008 |
Melatonin suppresses AOM/DSS-induced large bowel oncogenesis in rats.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Apoptosis; Azoxymethane; Biomarkers, Tumor; Colon; C | 2009 |
Metformin extends life span of HER-2/neu transgenic mice and in combination with melatonin inhibits growth of transplantable tumors in vivo.
Topics: Adenocarcinoma; Age Factors; Animals; Female; Longevity; Male; Mammary Neoplasms, Animal; Melatonin; | 2010 |
Melatonin, a novel Sirt1 inhibitor, imparts antiproliferative effects against prostate cancer in vitro in culture and in vivo in TRAMP model.
Topics: Adenocarcinoma; Animals; Blotting, Western; Cell Line, Tumor; Cell Proliferation; Humans; Immunoprec | 2011 |
Improvement of capecitabine antitumoral activity by melatonin in pancreatic cancer.
Topics: Adenocarcinoma; Animals; Antimetabolites, Antineoplastic; Antioxidants; Capecitabine; Cricetinae; De | 2011 |
Induction of cell differentiation and promotion of endocan gene expression in stomach cancer by melatonin.
Topics: Adenocarcinoma; Alkaline Phosphatase; Analysis of Variance; Blotting, Western; Cell Differentiation; | 2012 |
Circadian aspects of growth hormone-insulin-like growth factor axis function in patients with lung cancer.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous | 2012 |
Melatonin and beta-glucan alone or in combination inhibit the growth of dunning prostatic adenocarcinoma.
Topics: Adenocarcinoma; Animals; Antioxidants; beta-Glucans; Blotting, Western; Disease Models, Animal; Glut | 2011 |
Chronodisruption in lung cancer and possible therapeutic approaches.
Topics: Adenocarcinoma; Adult; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Chronobiology Disor | 2011 |
The modulatory effect of melatonin on genotoxicity of irinotecan in healthy human lymphocytes and cancer cells.
Topics: Adenocarcinoma; Adult; Antimutagenic Agents; Antineoplastic Agents, Phytogenic; Camptothecin; Carcin | 2013 |
The effect of melatonin treatment regimen on mammary adenocarcinoma development in HER-2/neu transgenic mice.
Topics: Adenocarcinoma; Animals; Antioxidants; Disease Progression; Female; Homozygote; Mammary Neoplasms, E | 2003 |
Exposure to light-at-night increases the growth of DMBA-induced mammary adenocarcinomas in rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Body Weight; Circadian Rhythm; Darkness; | 2006 |
Preventive and curative effect of melatonin on mammary carcinogenesis induced by dimethylbenz[a]anthracene in the female Sprague-Dawley rat.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Antioxidants; Carcinogens; Cell Transform | 2005 |
Growth-inhibitory action of melatonin and thiazolidinedione derivative CGP 52608 on murine 16/C breast cancer cells.
Topics: Adenocarcinoma; Animals; Antimetabolites, Antineoplastic; Antineoplastic Agents, Hormonal; Antineopl | 2006 |
Melatonin inhibition and pinealectomy enhancement of 7,12-dimethylbenz(a)anthracene-induced mammary tumors in the rat.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Benz(a)Anthracenes; Circadian Rhythm; Fem | 1981 |
ELF magnetic fields, breast cancer, and melatonin: 60 Hz fields block melatonin's oncostatic action on ER+ breast cancer cell proliferation.
Topics: Adenocarcinoma; Breast Neoplasms; Cell Division; Electromagnetic Fields; Humans; Melatonin; Radiatio | 1993 |
[Effect of melatonin on 1,2-dimethylhydrazine-induced intestinal tumors in rats].
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Animals; Carcinogens; Colonic Neoplasms; Dimethylhydrazines; | 1996 |
Melatonin and colon carcinogenesis: I. Inhibitory effect of melatonin on development of intestinal tumors induced by 1,2-dimethylhydrazine in rats.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Animals; Anticarcinogenic Agents; Body Weight; Colonic Neopla | 1997 |
Nocturnal urinary 6-sulfatoxymelatonin and proliferating cell nuclear antigen-immunopositive tumor cells show strong positive correlations in patients with gastrointestinal and lung cancer.
Topics: Adenocarcinoma; Aged; Carcinoma, Squamous Cell; Gastrointestinal Neoplasms; Humans; Immunoenzyme Tec | 1997 |
Serial transplants of DMBA-induced mammary tumors in Fischer rats as a model system for human breast cancer. VI. The role of different forms of tumor-associated stress for the regulation of pineal melatonin secretion.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Biopterins; Breast Neoplasms; Catecholami | 1999 |
The oncostatic action of melatonin in an ovarian carcinoma cell line.
Topics: Adenocarcinoma; Antineoplastic Agents; Apoptosis; Calcium; Cell Count; Cell Cycle; Cell Division; DN | 1999 |
Exposure of Sprague-Dawley rats to a 50-Hertz, 100-microTesla magnetic field for 27 weeks facilitates mammary tumorigenesis in the 7,12-dimethylbenz[a]-anthracene model of breast cancer.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Adenoma; Animals; Carcinogens; Circadian Rhythm; C | 1999 |
Melatonin and colon carcinogenesis. III. Effect of melatonin on proliferative activity and apoptosis in colon mucosa and colon tumors induced by 1,2-dimethylhydrazine in rats.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Animals; Apoptosis; Carcinogens; Cell Division; Colonic Neopl | 2000 |
Melatonin and 9-cis-retinoic acid in the chemoprevention of NMU-induced rat mammary carcinoma.
Topics: Adenocarcinoma; Alitretinoin; Animals; Anticarcinogenic Agents; Female; Mammary Neoplasms, Experimen | 1999 |
Differential growth inhibitory effect of melatonin on two endometrial cancer cell lines.
Topics: Adenocarcinoma; Antineoplastic Agents; Cell Count; Cell Division; Endometrial Neoplasms; Estradiol; | 2000 |
[Melatonin and serotonin in inflammatory colon diseases and colorectal neoplasms].
Topics: Adenocarcinoma; Adolescent; Adult; Aged; APUD Cells; Biomarkers, Tumor; Biopsy; Colitis; Colorectal | 2000 |
Serial transplants of DMBA-induced mammary tumors in fischer rats as model system for human breast cancer: V. Myoepithelial-mesenchymal conversion during passaging as possible cause for modulation of pineal-tumor interaction.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Actins; Adenocarcinoma; Animals; Disease Models, Animal; Epitheliu | 2000 |
Potential involvement of mt1 receptor and attenuated sex steroid-induced calcium influx in the direct anti-proliferative action of melatonin on androgen-responsive LNCaP human prostate cancer cells.
Topics: Adenocarcinoma; Blotting, Western; Calcium; Cell Division; Dihydrotestosterone; Dose-Response Relati | 2000 |
Disruption of mitochondrial respiration by melatonin in MCF-7 cells.
Topics: Adenocarcinoma; Adenosine Triphosphate; Antioxidants; Breast Neoplasms; Cell Respiration; Electron T | 2001 |
Chemoprevention of NMU-induced rat mammary carcinoma with the combination of melatonin and 9-cis-retinoic acid.
Topics: Adenocarcinoma; Alitretinoin; Animals; Anticarcinogenic Agents; Antioxidants; Body Weight; Carcinoge | 2001 |
Circadian rhythm of melatonin in patients with colorectal carcinoma.
Topics: Adenocarcinoma; Aged; Circadian Rhythm; Colorectal Neoplasms; Female; Humans; Male; Melatonin; Middl | 2002 |
MT(1) melatonin receptor overexpression enhances the growth suppressive effect of melatonin in human breast cancer cells.
Topics: Adenocarcinoma; Breast Neoplasms; Cell Division; Estrogen Receptor alpha; Estrogens; Female; Gene Ex | 2002 |
Endocrine and immune effects of melatonin therapy in metastatic cancer patients.
Topics: Adenocarcinoma; Aged; B-Lymphocytes; beta-Endorphin; Female; Growth Hormone; Humans; Insulin-Like Gr | 1989 |
Inhibition of Dunning tumor growth by melatonin.
Topics: Adenocarcinoma; Animals; Gonadotropin-Releasing Hormone; Male; Melatonin; Prostatic Neoplasms; Rats; | 1988 |
Studies on the effects of the pineal hormone melatonin on an androgen-insensitive rat prostatic adenocarcinoma, the Dunning R 3327 HIF tumor.
Topics: Adenocarcinoma; Androgens; Animals; Body Weight; Cell Line; Drug Implants; Male; Melatonin; Olfactor | 1988 |
Effects of olfactory bulbectomy, melatonin, and/or pinealectomy on three sublines of the Dunning R3327 rat prostatic adenocarcinoma.
Topics: Adenocarcinoma; Androgens; Animals; DNA; Genitalia, Male; Male; Melatonin; Neoplasm Transplantation; | 1987 |
[Polyfunctional endometrial adenocarcinoma producing melatonin, noradrenaline and chorionic gonadotropin].
Topics: Adenocarcinoma; Chorionic Gonadotropin; Female; Humans; Melatonin; Middle Aged; Norepinephrine; Uter | 1985 |
Influence of environmental light and melatonin upon mammary tumour induction.
Topics: Adenocarcinoma; Adenofibroma; Animals; Benz(a)Anthracenes; Carcinoma; Female; Light; Mammary Neoplas | 1969 |