melatonin has been researched along with Adenocarcinoma of Lung in 7 studies
Adenocarcinoma of Lung: A carcinoma originating in the lung and the most common lung cancer type in never-smokers. Malignant cells exhibit distinct features such as glandular epithelial, or tubular morphology. Mutations in KRAS, EGFR, BRAF, and ERBB2 genes are associated with this cancer.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Melatonin is a hormone synthesized in the pineal gland and has widespread physiological and pharmacological functions." | 5.72 | Melatonin may suppress lung adenocarcinoma progression via regulation of the circular noncoding RNA hsa_circ_0017109/miR-135b-3p/TOX3 axis. ( Duan, H; Duan, W; Li, X; Lu, G; Shao, C; Wang, J; Wang, Y; Wang, Z; Xie, M; Yan, X; Yu, W, 2022) |
| "Melatonin treatment also influenced the expression of HDAC-related molecules (HDAC1 and Ac-histone H3), upregulated the apoptosis-related molecules (PUMA and Bax), and downregulated the proliferation-related molecule (PCNA) and the anti-apoptosis-related molecule (Bcl2)." | 5.42 | HDAC1 inhibition by melatonin leads to suppression of lung adenocarcinoma cells via induction of oxidative stress and activation of apoptotic pathways. ( Di, S; Fan, C; Jiang, S; Li, T; Li, W; Li, X; Ma, Z; Pan, Y; Reiter, RJ; Yan, X; Yang, Y; Zhang, Z, 2015) |
| "Melatonin was tested on the cell line only after 24 h incubation (direct effect), and on the co-culture system of SK-LU-1 and PBMC to investigate any indirect effect." | 5.40 | Immunomodulatory effect of melatonin in SK-LU-1 human lung adenocarcinoma cells co-cultured with peripheral blood mononuclear cells. ( Barusrux, S; Johns, NP; Khamphio, M; Plaimee, P; Weerapreeyakul, N, 2014) |
| "Melatonin is a hormone synthesized in the pineal gland and has widespread physiological and pharmacological functions." | 1.72 | Melatonin may suppress lung adenocarcinoma progression via regulation of the circular noncoding RNA hsa_circ_0017109/miR-135b-3p/TOX3 axis. ( Duan, H; Duan, W; Li, X; Lu, G; Shao, C; Wang, J; Wang, Y; Wang, Z; Xie, M; Yan, X; Yu, W, 2022) |
| "Melatonin treatment also influenced the expression of HDAC-related molecules (HDAC1 and Ac-histone H3), upregulated the apoptosis-related molecules (PUMA and Bax), and downregulated the proliferation-related molecule (PCNA) and the anti-apoptosis-related molecule (Bcl2)." | 1.42 | HDAC1 inhibition by melatonin leads to suppression of lung adenocarcinoma cells via induction of oxidative stress and activation of apoptotic pathways. ( Di, S; Fan, C; Jiang, S; Li, T; Li, W; Li, X; Ma, Z; Pan, Y; Reiter, RJ; Yan, X; Yang, Y; Zhang, Z, 2015) |
| "Melatonin was tested on the cell line only after 24 h incubation (direct effect), and on the co-culture system of SK-LU-1 and PBMC to investigate any indirect effect." | 1.40 | Immunomodulatory effect of melatonin in SK-LU-1 human lung adenocarcinoma cells co-cultured with peripheral blood mononuclear cells. ( Barusrux, S; Johns, NP; Khamphio, M; Plaimee, P; Weerapreeyakul, N, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (57.14) | 24.3611 |
| 2020's | 3 (42.86) | 2.80 |
| Authors | Studies |
|---|---|
| He, L | 1 |
| Fan, Y | 1 |
| Zhang, Y | 2 |
| Tu, T | 1 |
| Zhang, Q | 2 |
| Yuan, F | 1 |
| Cheng, C | 1 |
| Wang, Y | 2 |
| Wang, Z | 1 |
| Shao, C | 1 |
| Lu, G | 1 |
| Xie, M | 1 |
| Wang, J | 1 |
| Duan, H | 1 |
| Li, X | 3 |
| Yu, W | 1 |
| Duan, W | 1 |
| Yan, X | 2 |
| Sun, Q | 1 |
| Zhang, J | 1 |
| Yang, G | 1 |
| Cheng, S | 1 |
| Guo, D | 1 |
| Sun, F | 1 |
| Zhao, F | 1 |
| Yang, D | 1 |
| Wang, S | 1 |
| Wang, T | 1 |
| Liu, S | 1 |
| Zou, L | 1 |
| Liu, H | 1 |
| Zhou, Q | 2 |
| Gui, S | 1 |
| Plaimee, P | 2 |
| Khamphio, M | 1 |
| Weerapreeyakul, N | 2 |
| Barusrux, S | 2 |
| Johns, NP | 2 |
| Fan, C | 1 |
| Pan, Y | 1 |
| Yang, Y | 1 |
| Di, S | 1 |
| Jiang, S | 1 |
| Ma, Z | 1 |
| Li, T | 1 |
| Zhang, Z | 1 |
| Li, W | 1 |
| Reiter, RJ | 1 |
7 other studies available for melatonin and Adenocarcinoma of Lung
| Article | Year |
|---|---|
Single-cell transcriptomic analysis reveals circadian rhythm disruption associated with poor prognosis and drug-resistance in lung adenocarcinoma.
Topics: Adenocarcinoma of Lung; Circadian Rhythm; Humans; Lung Neoplasms; Melatonin; Prognosis; Transcriptom | 2022 |
Melatonin may suppress lung adenocarcinoma progression via regulation of the circular noncoding RNA hsa_circ_0017109/miR-135b-3p/TOX3 axis.
Topics: Adenocarcinoma of Lung; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Proliferation; Diseas | 2022 |
The ubiquitin-specific protease 8 antagonizes melatonin-induced endocytic degradation of MT
Topics: Adenocarcinoma; Adenocarcinoma of Lung; Animals; Humans; Lung Neoplasms; Melatonin; Receptor, Melato | 2022 |
Melatonin inhibits the migration of human lung adenocarcinoma A549 cell lines involving JNK/MAPK pathway.
Topics: Adenocarcinoma; Adenocarcinoma of Lung; Antineoplastic Agents; Antioxidants; Cell Line, Tumor; Cell | 2014 |
Immunomodulatory effect of melatonin in SK-LU-1 human lung adenocarcinoma cells co-cultured with peripheral blood mononuclear cells.
Topics: Adenocarcinoma; Adenocarcinoma of Lung; Antineoplastic Agents; Antioxidants; Apoptosis; Cell Line, T | 2014 |
Melatonin potentiates cisplatin-induced apoptosis and cell cycle arrest in human lung adenocarcinoma cells.
Topics: Adenocarcinoma; Adenocarcinoma of Lung; Antineoplastic Agents; Apoptosis; Cell Cycle Checkpoints; Ce | 2015 |
HDAC1 inhibition by melatonin leads to suppression of lung adenocarcinoma cells via induction of oxidative stress and activation of apoptotic pathways.
Topics: Adenocarcinoma; Adenocarcinoma of Lung; Apoptosis; Cell Line, Tumor; Cell Survival; Glutathione; His | 2015 |