melatonin has been researched along with Acute Hepatic Failure in 9 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| " Accordingly, this work indicates that mPEG-b-PPS-NPs show potential as an ROS-mediated on-demand drug delivery system for improving Mel bioavailability and treating oxidative stress-associated diseases such as sepsis-induced acute liver injury." | 1.46 | Reactive oxygen species-responsive polymeric nanoparticles for alleviating sepsis-induced acute liver injury in mice. ( Chen, G; Deng, H; Dong, A; Lu, M; Song, X; Xia, S; You, G; Zhang, Y; Zhao, J; Zhao, L; Zhou, H, 2017) |
| "Melatonin treatment also resulted in decreased immunoreactivity for RHDV viral VP60 antigen and a significantly reduction in RHDV VP60 mRNA levels, oxidized to reduced glutathione ratio (GSSG/GSH), caspase-3 activity, and immunoglobulin-heavy-chain-binding protein (BiP) and CCAAT/enhancer-binding protein homologous protein (CHOP) expression." | 1.40 | Melatonin modulates the autophagic response in acute liver failure induced by the rabbit hemorrhagic disease virus. ( Álvarez, M; Crespo, I; González-Gallego, J; Prieto, J; San-Miguel, B; Tuñón, MJ; Vallejo, D, 2014) |
| "Melatonin treatment also resulted in reduced expression of phosphorylated Janus kinase and enhanced expression of extracellular mitogen-activated protein kinase (ERK) and signal transducer and activator of transcription (STAT) 3." | 1.38 | Melatonin attenuates inflammation and promotes regeneration in rabbits with fulminant hepatitis of viral origin. ( Alvarez, M; Crespo, I; González-Gallego, J; Laliena, A; San Miguel, B; Tuñón, MJ, 2012) |
| "Melatonin treatment also resulted in a reduction in caspase-8 activity, tumor necrosis factor receptor-1 (TNF-R1) expression, and phosphorylated Janus kinase (JNK) expression, and increased expression of cellular FLICE-inhibitory protein (c-FLIP)." | 1.37 | Melatonin attenuates apoptotic liver damage in fulminant hepatic failure induced by the rabbit hemorrhagic disease virus. ( Alvarez, M; Crespo, I; González-Gallego, J; Jorquera, F; Prieto, J; San Miguel, B; Santamaría, E; Tuñón, MJ, 2011) |
| "Melatonin treatment was not accompanied by changes in protein levels of Kelch-like ECH-associating protein 1 (Keap1) but resulted in an increased protein expression of Nrf2 in the cytoplasm and the nucleus, which was confirmed by the results of Nrf2 immunostaining." | 1.36 | Melatonin prevents the decreased activity of antioxidant enzymes and activates nuclear erythroid 2-related factor 2 signaling in an animal model of fulminant hepatic failure of viral origin. ( Alvarez, M; Crespo, I; Culebras, JM; González-Gallego, J; Laliena, A; Miguel, BS; Tuñón, MJ, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 8 (88.89) | 24.3611 |
| 2020's | 1 (11.11) | 2.80 |
| Authors | Studies |
|---|---|
| Crespo, I | 7 |
| Fernández-Palanca, P | 1 |
| San-Miguel, B | 4 |
| Álvarez, M | 7 |
| González-Gallego, J | 7 |
| Tuñón, MJ | 7 |
| Chen, G | 1 |
| Deng, H | 1 |
| Song, X | 1 |
| Lu, M | 1 |
| Zhao, L | 1 |
| Xia, S | 1 |
| You, G | 1 |
| Zhao, J | 1 |
| Zhang, Y | 1 |
| Dong, A | 1 |
| Zhou, H | 1 |
| Laliena, A | 3 |
| Vallejo, D | 2 |
| Prieto, J | 3 |
| Sánchez, DI | 1 |
| González-Fernández, B | 1 |
| Miguel, BS | 1 |
| Culebras, JM | 1 |
| San Miguel, B | 2 |
| Jorquera, F | 1 |
| Santamaría, E | 1 |
| Liang, YL | 1 |
| Zhang, ZH | 1 |
| Liu, XJ | 1 |
| Liu, XQ | 1 |
| Tao, L | 1 |
| Zhang, YF | 1 |
| Wang, H | 1 |
| Zhang, C | 1 |
| Chen, X | 1 |
| Xu, DX | 1 |
9 other studies available for melatonin and Acute Hepatic Failure
| Article | Year |
|---|---|
Melatonin modulates mitophagy, innate immunity and circadian clocks in a model of viral-induced fulminant hepatic failure.
Topics: Animals; Biomarkers; Capsid Proteins; Circadian Clocks; Disease Models, Animal; Hemorrhagic Disease | 2020 |
Reactive oxygen species-responsive polymeric nanoparticles for alleviating sepsis-induced acute liver injury in mice.
Topics: Animals; Antioxidants; Delayed-Action Preparations; Liver Failure, Acute; Male; Melatonin; Mice; Mic | 2017 |
Melatonin treatment reduces endoplasmic reticulum stress and modulates the unfolded protein response in rabbits with lethal fulminant hepatitis of viral origin.
Topics: Animals; Antioxidants; Apoptosis; Caliciviridae Infections; Disease Models, Animal; Endoplasmic Reti | 2013 |
Melatonin modulates the autophagic response in acute liver failure induced by the rabbit hemorrhagic disease virus.
Topics: Animals; Autophagy; Caliciviridae Infections; Disease Models, Animal; Hemorrhagic Disease Virus, Rab | 2014 |
Melatonin inhibits the sphingosine kinase 1/sphingosine-1-phosphate signaling pathway in rabbits with fulminant hepatitis of viral origin.
Topics: Animals; Caliciviridae Infections; Hemorrhagic Disease Virus, Rabbit; Hepatitis, Viral, Animal; Live | 2016 |
Melatonin prevents the decreased activity of antioxidant enzymes and activates nuclear erythroid 2-related factor 2 signaling in an animal model of fulminant hepatic failure of viral origin.
Topics: Analysis of Variance; Animals; Antioxidants; Blotting, Western; Cell Nucleus; Cytosol; Glutathione P | 2010 |
Melatonin attenuates apoptotic liver damage in fulminant hepatic failure induced by the rabbit hemorrhagic disease virus.
Topics: Animals; Apoptosis; Blotting, Western; Caspases; Hemorrhagic Disease Virus, Rabbit; Immunohistochemi | 2011 |
Melatonin attenuates inflammation and promotes regeneration in rabbits with fulminant hepatitis of viral origin.
Topics: Animals; Caliciviridae Infections; Hemorrhagic Disease Virus, Rabbit; HMGB1 Protein; Interleukin-1be | 2012 |
Melatonin protects against apoptosis-inducing factor (AIF)-dependent cell death during acetaminophen-induced acute liver failure.
Topics: Acetaminophen; Animals; Antioxidants; Apoptosis Inducing Factor; Cell Death; Cytochrome P-450 CYP2E1 | 2012 |