melatonin has been researched along with Absence Status in 9 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| " The present study aimed to explore and compare the efficacy of chronic pretreatment with melatonin infused via subcutaneous osmotic mini-pumps for 14 days (10 mg/kg per day) on kainic acid (KA)-induced status epilepticus, oxidative stress and expression of heat shock protein (HSP) 72 in spontaneously hypertensive rats (SHRs) and normotensive Wistar rats." | 7.79 | Strain-dependent effects of long-term treatment with melatonin on kainic acid-induced status epilepticus, oxidative stress and the expression of heat shock proteins. ( Atanasova, M; Blazhev, A; Dragomirova, P; Pechlivanova, D; Petkova, Z; Tchekalarova, J, 2013) |
| "Melatonin treatment for 7 days showed a decrease in seizure intensity (28%), latency to reach score 5 (14 min), and duration of SE (29%)." | 5.72 | Melatonin Pretreatment Protects Against Status epilepticus, Glutamate Transport, and Oxidative Stress Induced by Kainic Acid in Zebrafish. ( Baldin, SL; Bernardo, HT; de Farias, ACS; de Pieri Pickler, K; Dondossola, ER; Rico, EP, 2022) |
| "Melatonin is a potent antioxidant which showed anticonvulsant activities both in experimental and clinical studies." | 5.39 | Prophylactic treatment with melatonin after status epilepticus: effects on epileptogenesis, neuronal damage, and behavioral changes in a kainate model of temporal lobe epilepsy. ( Atanasova, D; Kortenska, L; Lazarov, N; Lozanov, V; Mitreva, R; Moyanova, S; Pechlivanova, D; Petkova, Z; Stoynev, A; Tchekalarova, J, 2013) |
| " Last, CPEB4-deficient mice showed altered circadian function, including altered melatonin blood levels and altered clustering of spontaneous seizures during the day." | 4.31 | CPEB4-CLOCK crosstalk during temporal lobe epilepsy. ( Alves, M; Auer, T; Beausang, A; Brennan, GP; Brett, FM; Carracedo-Rodríguez, G; Cryan, J; de Diego-Garcia, L; Delanty, N; Engel, T; Farrell, MA; Gil, B; Henshall, DC; Lau, K; Lucas, JJ; Martin-Gil, A; Mendez, R; Menendez-Mendez, A; Mitra, M; O'Brien, DF; Ollà, I; Parras, A; Villalba-Benito, L, 2023) |
| "This is the first study to reveal the relationship between ESs and basal melatonin levels according to all the characteristics of seizure and epilepsy in the largest patient group." | 3.96 | The relationship between epileptic seizure and melatonin in children. ( Aksu Uzunhan, T; Kacar, A; Kucur, M; Saltik, S; Tarcin, G, 2020) |
| " The present study aimed to explore and compare the efficacy of chronic pretreatment with melatonin infused via subcutaneous osmotic mini-pumps for 14 days (10 mg/kg per day) on kainic acid (KA)-induced status epilepticus, oxidative stress and expression of heat shock protein (HSP) 72 in spontaneously hypertensive rats (SHRs) and normotensive Wistar rats." | 3.79 | Strain-dependent effects of long-term treatment with melatonin on kainic acid-induced status epilepticus, oxidative stress and the expression of heat shock proteins. ( Atanasova, M; Blazhev, A; Dragomirova, P; Pechlivanova, D; Petkova, Z; Tchekalarova, J, 2013) |
| "Melatonin was used as positive control while the melatonin receptor antagonist Luzindol was studied alone or in combination with melatonin or 3e, respectively." | 1.72 | The Anticonvulsant Effect of a Novel Indole-Related Compound in the Kainate-Induced Status Epilepticus in Mice: The Role of the Antioxidant and Anti-inflammatory Mechanism. ( Andreeva-Gateva, P; Angelova, V; Stoyanova, T; Tchekalarova, J; Tzoneva, R, 2022) |
| "Melatonin treatment for 7 days showed a decrease in seizure intensity (28%), latency to reach score 5 (14 min), and duration of SE (29%)." | 1.72 | Melatonin Pretreatment Protects Against Status epilepticus, Glutamate Transport, and Oxidative Stress Induced by Kainic Acid in Zebrafish. ( Baldin, SL; Bernardo, HT; de Farias, ACS; de Pieri Pickler, K; Dondossola, ER; Rico, EP, 2022) |
| "Melatonin is a potent antioxidant which showed anticonvulsant activities both in experimental and clinical studies." | 1.39 | Prophylactic treatment with melatonin after status epilepticus: effects on epileptogenesis, neuronal damage, and behavioral changes in a kainate model of temporal lobe epilepsy. ( Atanasova, D; Kortenska, L; Lazarov, N; Lozanov, V; Mitreva, R; Moyanova, S; Pechlivanova, D; Petkova, Z; Stoynev, A; Tchekalarova, J, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (11.11) | 29.6817 |
| 2010's | 3 (33.33) | 24.3611 |
| 2020's | 5 (55.56) | 2.80 |
| Authors | Studies |
|---|---|
| Tchekalarova, J | 3 |
| Stoyanova, T | 1 |
| Tzoneva, R | 1 |
| Angelova, V | 1 |
| Andreeva-Gateva, P | 1 |
| de Farias, ACS | 1 |
| de Pieri Pickler, K | 1 |
| Bernardo, HT | 1 |
| Baldin, SL | 1 |
| Dondossola, ER | 1 |
| Rico, EP | 1 |
| Atacan Yaşgüçlükal, M | 1 |
| Ayça, S | 1 |
| Demirbilek, V | 1 |
| Saltık, S | 2 |
| Yalçınkaya, C | 1 |
| Erdoğan Döventaş, Y | 1 |
| Çokar, Ö | 1 |
| de Diego-Garcia, L | 1 |
| Brennan, GP | 1 |
| Auer, T | 1 |
| Menendez-Mendez, A | 1 |
| Parras, A | 1 |
| Martin-Gil, A | 1 |
| Mitra, M | 1 |
| Ollà, I | 1 |
| Villalba-Benito, L | 1 |
| Gil, B | 1 |
| Alves, M | 1 |
| Lau, K | 1 |
| Delanty, N | 1 |
| Beausang, A | 1 |
| Cryan, J | 1 |
| Brett, FM | 1 |
| Farrell, MA | 1 |
| O'Brien, DF | 1 |
| Mendez, R | 1 |
| Carracedo-Rodríguez, G | 1 |
| Henshall, DC | 1 |
| Lucas, JJ | 1 |
| Engel, T | 1 |
| Tarcin, G | 1 |
| Aksu Uzunhan, T | 1 |
| Kacar, A | 1 |
| Kucur, M | 1 |
| Petkova, Z | 2 |
| Pechlivanova, D | 2 |
| Moyanova, S | 1 |
| Kortenska, L | 1 |
| Mitreva, R | 1 |
| Lozanov, V | 1 |
| Atanasova, D | 1 |
| Lazarov, N | 1 |
| Stoynev, A | 1 |
| Atanasova, M | 1 |
| Dragomirova, P | 1 |
| Blazhev, A | 1 |
| Lima, E | 1 |
| Cabral, FR | 1 |
| Cavalheiro, EA | 1 |
| Naffah-Mazzacoratti, Mda G | 1 |
| Amado, D | 2 |
| de Lima, E | 1 |
| Soares, JM | 1 |
| del Carmen Sanabria Garrido, Y | 1 |
| Gomes Valente, S | 1 |
| Priel, MR | 1 |
| Chada Baracat, E | 1 |
| Abrão Cavalheiro, E | 1 |
| da Graça Naffah-Mazzacoratti, M | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effect of Melatonin on Seizure Outcome, Neuronal Damage and Quality of Life in Patients With Generalized Epilepsy: A Randomized, add-on Placebo-controlled Clinical Trial[NCT03590197] | Phase 4 | 104 participants (Actual) | Interventional | 2018-08-06 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
9 other studies available for melatonin and Absence Status
| Article | Year |
|---|---|
The Anticonvulsant Effect of a Novel Indole-Related Compound in the Kainate-Induced Status Epilepticus in Mice: The Role of the Antioxidant and Anti-inflammatory Mechanism.
Topics: Animals; Anti-Inflammatory Agents; Anticonvulsants; Antioxidants; Hippocampus; Kainic Acid; Melatoni | 2022 |
Melatonin Pretreatment Protects Against Status epilepticus, Glutamate Transport, and Oxidative Stress Induced by Kainic Acid in Zebrafish.
Topics: Amino Acid Transport System X-AG; Animals; Antioxidants; Catalase; Glutamic Acid; Glutathione; Kaini | 2022 |
Serum Levels of Neuropeptides in Epileptic Encephalopathy With Spike-and-Wave Activation in Sleep.
Topics: Adolescent; Child; Child, Preschool; Electroencephalography; Epilepsies, Partial; Epilepsy, Generali | 2023 |
CPEB4-CLOCK crosstalk during temporal lobe epilepsy.
Topics: Animals; CLOCK Proteins; Drug Resistant Epilepsy; Epilepsy, Temporal Lobe; Hippocampus; Humans; Male | 2023 |
The relationship between epileptic seizure and melatonin in children.
Topics: Child; Electroencephalography; Epilepsy; Humans; Melatonin; Seizures; Status Epilepticus | 2020 |
Prophylactic treatment with melatonin after status epilepticus: effects on epileptogenesis, neuronal damage, and behavioral changes in a kainate model of temporal lobe epilepsy.
Topics: Analysis of Variance; Animals; Central Nervous System Depressants; Chromatography, High Pressure Liq | 2013 |
Strain-dependent effects of long-term treatment with melatonin on kainic acid-induced status epilepticus, oxidative stress and the expression of heat shock proteins.
Topics: Animals; Blotting, Western; Cytosol; Heat-Shock Proteins; Kainic Acid; Male; Melatonin; Mitochondria | 2013 |
Melatonin administration after pilocarpine-induced status epilepticus: a new way to prevent or attenuate postlesion epilepsy?
Topics: Analysis of Variance; Animals; Antioxidants; Cell Death; Disease Models, Animal; Hippocampus; Male; | 2011 |
Effects of pinealectomy and the treatment with melatonin on the temporal lobe epilepsy in rats.
Topics: Animals; Anticonvulsants; Apoptosis; Denervation; Disease Models, Animal; Epilepsy, Temporal Lobe; H | 2005 |