melatonin has been researched along with Abnormalities, Multiple in 7 studies
Abnormalities, Multiple: Congenital abnormalities that affect more than one organ or body structure.
| Excerpt | Relevance | Reference |
|---|---|---|
| "An inverted circadian rhythm of melatonin (MT) likely contributes to the sleep disturbance in patients with Smith-Magenis syndrome (SMS)." | 7.76 | Diagnostic utility of daytime salivary melatonin levels in Smith-Magenis syndrome. ( Chik, CL; Duncan, WC; Rollag, MD; Smith, AC, 2010) |
| "The objective was to determine the circadian rhythm of melatonin in the Smith-Magenis syndrome (SMS), which causes behavioral problems and sleep disturbance." | 7.71 | Inversion of the circadian rhythm of melatonin in the Smith-Magenis syndrome. ( Albrecht, U; Claustrat, B; De Blois, MC; De Leersnyder, H; Delobel, B; Lyonnet, S; Munnich, A; Romana, S; Vekemans, M; Viot, G; Von Kleist-Retzow, JC, 2001) |
| "Our data indicate a disturbed circadian rhythm in melatonin and document the disturbed sleep pattern in Smith-Magenis syndrome." | 7.70 | Circadian rhythm abnormalities of melatonin in Smith-Magenis syndrome. ( Glaze, D; Kashork, CD; Lupski, JR; Park, SS; Potocki, L; Reiter, RJ; Shaffer, LG; Tan, DX, 2000) |
| "Smith-Magenis syndrome (SMS) is a mental retardation syndrome with distinctive behavioral characteristics, dysmorphic features and congenital anomalies ascribed to an interstitial deletion of chromosome 17p11." | 6.43 | Inverted rhythm of melatonin secretion in Smith-Magenis syndrome: from symptoms to treatment. ( De Leersnyder, H, 2006) |
| "Mental retardation is constant; there are major behavioral disturbances and severe sleep disorders." | 5.32 | [Inversion of the circadian melatonin rhythm in Smith-Magenis syndrome]. ( Bresson, JL; Claustrat, B; de Blois, MC; De Leersnyder, H; Munnich, A; Sidi, D, 2003) |
| "An inverted circadian rhythm of melatonin (MT) likely contributes to the sleep disturbance in patients with Smith-Magenis syndrome (SMS)." | 3.76 | Diagnostic utility of daytime salivary melatonin levels in Smith-Magenis syndrome. ( Chik, CL; Duncan, WC; Rollag, MD; Smith, AC, 2010) |
| "The objective was to determine the circadian rhythm of melatonin in the Smith-Magenis syndrome (SMS), which causes behavioral problems and sleep disturbance." | 3.71 | Inversion of the circadian rhythm of melatonin in the Smith-Magenis syndrome. ( Albrecht, U; Claustrat, B; De Blois, MC; De Leersnyder, H; Delobel, B; Lyonnet, S; Munnich, A; Romana, S; Vekemans, M; Viot, G; Von Kleist-Retzow, JC, 2001) |
| "Our data indicate a disturbed circadian rhythm in melatonin and document the disturbed sleep pattern in Smith-Magenis syndrome." | 3.70 | Circadian rhythm abnormalities of melatonin in Smith-Magenis syndrome. ( Glaze, D; Kashork, CD; Lupski, JR; Park, SS; Potocki, L; Reiter, RJ; Shaffer, LG; Tan, DX, 2000) |
| "Smith-Magenis syndrome (SMS) is a mental retardation syndrome with distinctive behavioral characteristics, dysmorphic features and congenital anomalies ascribed to an interstitial deletion of chromosome 17p11." | 2.43 | Inverted rhythm of melatonin secretion in Smith-Magenis syndrome: from symptoms to treatment. ( De Leersnyder, H, 2006) |
| "Mental retardation is constant; there are major behavioral disturbances and severe sleep disorders." | 1.32 | [Inversion of the circadian melatonin rhythm in Smith-Magenis syndrome]. ( Bresson, JL; Claustrat, B; de Blois, MC; De Leersnyder, H; Munnich, A; Sidi, D, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 6 (85.71) | 29.6817 |
| 2010's | 1 (14.29) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Boudreau, EA | 1 |
| Johnson, KP | 1 |
| Jackman, AR | 1 |
| Blancato, J | 1 |
| Huizing, M | 1 |
| Bendavid, C | 1 |
| Jones, M | 1 |
| Chandrasekharappa, SC | 1 |
| Lewy, AJ | 1 |
| Smith, AC | 2 |
| Magenis, RE | 1 |
| Chik, CL | 1 |
| Rollag, MD | 1 |
| Duncan, WC | 1 |
| De Leersnyder, H | 4 |
| Bresson, JL | 2 |
| de Blois, MC | 3 |
| Souberbielle, JC | 1 |
| Mogenet, A | 1 |
| Delhotal-Landes, B | 1 |
| Salefranque, F | 1 |
| Munnich, A | 3 |
| Sidi, D | 1 |
| Claustrat, B | 2 |
| Potocki, L | 1 |
| Glaze, D | 1 |
| Tan, DX | 1 |
| Park, SS | 1 |
| Kashork, CD | 1 |
| Shaffer, LG | 1 |
| Reiter, RJ | 1 |
| Lupski, JR | 1 |
| Romana, S | 1 |
| Albrecht, U | 1 |
| Von Kleist-Retzow, JC | 1 |
| Delobel, B | 1 |
| Viot, G | 1 |
| Lyonnet, S | 1 |
| Vekemans, M | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Melatonin Levels in Sleep-disordered Smith-Magenis Syndrome: a Pilot Study[NCT00691574] | 5 participants (Actual) | Interventional | 1998-09-30 | Terminated (stopped due to Unique provision in the American Recovery and Reinvestment Act prevented approval of second year no-cost-extension in which completion of analyses were planned.) | |||
| Characterization of Endogenous Melatonin Profiles in Children With Autism Spectrum Disorder.[NCT00691080] | 58 participants (Actual) | Observational | 2007-09-30 | Completed | |||
| A Phase One Treatment Trial of the Circadian Sleep Disturbance in Smith-Magenis Syndrome (SMS)[NCT00506259] | Phase 1 | 23 participants (Actual) | Interventional | 2007-07-17 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for melatonin and Abnormalities, Multiple
| Article | Year |
|---|---|
Inverted rhythm of melatonin secretion in Smith-Magenis syndrome: from symptoms to treatment.
Topics: Abnormalities, Multiple; Circadian Rhythm; Humans; Intellectual Disability; Melatonin; Sleep Wake Di | 2006 |
1 trial available for melatonin and Abnormalities, Multiple
| Article | Year |
|---|---|
Beta 1-adrenergic antagonists and melatonin reset the clock and restore sleep in a circadian disorder, Smith-Magenis syndrome.
Topics: Abnormalities, Multiple; Acebutolol; Adolescent; Adrenergic beta-1 Receptor Antagonists; Adrenergic | 2003 |
5 other studies available for melatonin and Abnormalities, Multiple
| Article | Year |
|---|---|
Review of disrupted sleep patterns in Smith-Magenis syndrome and normal melatonin secretion in a patient with an atypical interstitial 17p11.2 deletion.
Topics: Abnormalities, Multiple; Chromosome Deletion; Chromosomes, Human, Pair 17; Female; Humans; Intellect | 2009 |
Diagnostic utility of daytime salivary melatonin levels in Smith-Magenis syndrome.
Topics: Abnormalities, Multiple; Adolescent; Adult; Antipsychotic Agents; Case-Control Studies; Child; Child | 2010 |
[Inversion of the circadian melatonin rhythm in Smith-Magenis syndrome].
Topics: Abnormalities, Multiple; Adolescent; Adrenergic beta-Antagonists; Child; Child, Preschool; Chromosom | 2003 |
Circadian rhythm abnormalities of melatonin in Smith-Magenis syndrome.
Topics: Abnormalities, Multiple; Adolescent; Adult; Child; Child, Preschool; Chromosomes, Human, Pair 17; Ci | 2000 |
Circadian rhythm abnormalities of melatonin in Smith-Magenis syndrome.
Topics: Abnormalities, Multiple; Adolescent; Adult; Child; Child, Preschool; Chromosomes, Human, Pair 17; Ci | 2000 |
Circadian rhythm abnormalities of melatonin in Smith-Magenis syndrome.
Topics: Abnormalities, Multiple; Adolescent; Adult; Child; Child, Preschool; Chromosomes, Human, Pair 17; Ci | 2000 |
Circadian rhythm abnormalities of melatonin in Smith-Magenis syndrome.
Topics: Abnormalities, Multiple; Adolescent; Adult; Child; Child, Preschool; Chromosomes, Human, Pair 17; Ci | 2000 |
Inversion of the circadian rhythm of melatonin in the Smith-Magenis syndrome.
Topics: Abnormalities, Multiple; Adolescent; Case-Control Studies; Child; Child Behavior Disorders; Child, P | 2001 |