Page last updated: 2024-10-19

melatonin and Abdominal Pain

melatonin has been researched along with Abdominal Pain in 12 studies

Abdominal Pain: Sensation of discomfort, distress, or agony in the abdominal region.

Research Excerpts

ExcerptRelevanceReference
"This is the first study to investigate the role of the combination of melatonin and Lactobacillus Rhamnosus GG in the treatment of children with functional abdominal pain disorders."9.69Randomised controlled trial of melatonin for paediatric functional abdominal pain disorders. ( Barbalace, A; Dipasquale, V; Palermo, L; Romano, C; Tumminello, G, 2023)
"Melatonin can be used as part of the treatment of IBS, particularly in patients with constipation-predominant IBS."9.17Influence of melatonin on symptoms of irritable bowel syndrome in postmenopausal women. ( Chojnacki, C; Chojnacki, J; Klupińska, G; Lokieć, K; Pawłowicz, M; Walecka-Kapica, E; Winczyk, K, 2013)
"Melatonin can be considered as an auxiliary drug in the treatment of ulcerlike dyspepsia."9.12Therapeutic effect of melatonin in patients with functional dyspepsia. ( Blasiak, J; Chojnacki, J; Drzewoski, J; Harasiuk, A; Klupińska, G; Poplawski, T; Reiter, RJ, 2007)
"Compared with placebo, melatonin taken for two weeks significantly decreased mean abdominal pain score (2."9.11Melatonin improves abdominal pain in irritable bowel syndrome patients who have sleep disturbances: a randomised, double blind, placebo controlled study. ( Gwee, KA; Ho, KY; Leng, PH; Moochhala, SM; Song, GH, 2005)
"In patients with sleep disorders, significant improvement in sleep parameters, including subjective sleep quality, sleep latency, sleep duration, sleep efficiency, and daytime dysfunction, was observed, while in patients without sleep disorders, there was no significant improvement in sleep parameters."7.30The effect of melatonin on irritable bowel syndrome patients with and without sleep disorders: a randomized double-blinded placebo-controlled trial study. ( Abbasian, S; Faghih Dinevari, M; Jabbaripour Sarmadian, A; Jafarzadeh, F; Nikniaz, Z; Riazi, A, 2023)
"The treatment with melatonin seems to be suitable in combined therapy of functional dyspepsia."6.73[The influence of melatonin on concentration of nitric oxide metabolites in gastric juice in subjects with functional dyspepsia]. ( Chojnacki, C; Felicka, E; Foryś, S; Harasiuk, A; Klupińska, G; Walecka-Kapica, E, 2007)
"Melatonin treatment has an extremely wide margin of safety though it may cause minor adverse effects, such as headache, rash and nightmares."6.50Melatonin for the treatment of irritable bowel syndrome. ( Ho, KY; Siah, KT; Wong, RK, 2014)
"This is the first study to investigate the role of the combination of melatonin and Lactobacillus Rhamnosus GG in the treatment of children with functional abdominal pain disorders."5.69Randomised controlled trial of melatonin for paediatric functional abdominal pain disorders. ( Barbalace, A; Dipasquale, V; Palermo, L; Romano, C; Tumminello, G, 2023)
"Melatonin can be used as part of the treatment of IBS, particularly in patients with constipation-predominant IBS."5.17Influence of melatonin on symptoms of irritable bowel syndrome in postmenopausal women. ( Chojnacki, C; Chojnacki, J; Klupińska, G; Lokieć, K; Pawłowicz, M; Walecka-Kapica, E; Winczyk, K, 2013)
"Melatonin can be considered as an auxiliary drug in the treatment of ulcerlike dyspepsia."5.12Therapeutic effect of melatonin in patients with functional dyspepsia. ( Blasiak, J; Chojnacki, J; Drzewoski, J; Harasiuk, A; Klupińska, G; Poplawski, T; Reiter, RJ, 2007)
"Compared with placebo, melatonin taken for two weeks significantly decreased mean abdominal pain score (2."5.11Melatonin improves abdominal pain in irritable bowel syndrome patients who have sleep disturbances: a randomised, double blind, placebo controlled study. ( Gwee, KA; Ho, KY; Leng, PH; Moochhala, SM; Song, GH, 2005)
"In patients with sleep disorders, significant improvement in sleep parameters, including subjective sleep quality, sleep latency, sleep duration, sleep efficiency, and daytime dysfunction, was observed, while in patients without sleep disorders, there was no significant improvement in sleep parameters."3.30The effect of melatonin on irritable bowel syndrome patients with and without sleep disorders: a randomized double-blinded placebo-controlled trial study. ( Abbasian, S; Faghih Dinevari, M; Jabbaripour Sarmadian, A; Jafarzadeh, F; Nikniaz, Z; Riazi, A, 2023)
"The treatment with melatonin seems to be suitable in combined therapy of functional dyspepsia."2.73[The influence of melatonin on concentration of nitric oxide metabolites in gastric juice in subjects with functional dyspepsia]. ( Chojnacki, C; Felicka, E; Foryś, S; Harasiuk, A; Klupińska, G; Walecka-Kapica, E, 2007)
"Melatonin treatment has an extremely wide margin of safety though it may cause minor adverse effects, such as headache, rash and nightmares."2.50Melatonin for the treatment of irritable bowel syndrome. ( Ho, KY; Siah, KT; Wong, RK, 2014)
"We hypothesized that infantile colic might associate with desynchronization of normal circadian rhythms of these hormones."1.48The role of melatonin and cortisol circadian rhythms in the pathogenesis of infantile colic. ( Akman, H; Aydın, A; Çimrin, D; İnce, T, 2018)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's5 (41.67)29.6817
2010's5 (41.67)24.3611
2020's2 (16.67)2.80

Authors

AuthorsStudies
Dipasquale, V1
Palermo, L1
Barbalace, A1
Tumminello, G1
Romano, C1
Faghih Dinevari, M1
Jafarzadeh, F1
Jabbaripour Sarmadian, A1
Abbasian, S1
Nikniaz, Z1
Riazi, A1
İnce, T1
Akman, H1
Çimrin, D1
Aydın, A1
Chojnacki, C4
Walecka-Kapica, E3
Lokieć, K1
Pawłowicz, M1
Winczyk, K1
Chojnacki, J3
Klupińska, G5
Poplawski, T2
Blasiak, J2
Chen, C1
Fichna, J1
Laudon, M1
Storr, M1
Siah, KT1
Wong, RK1
Ho, KY2
Ducrotté, P1
Song, GH1
Leng, PH1
Gwee, KA1
Moochhala, SM1
Drzewoski, J1
Harasiuk, A3
Reiter, RJ1
Felicka, E2
Foryś, S2
Piotrowski, W1

Clinical Trials (4)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
The Therapeutic Effect of Melatonin in Pediatric Patients With Functional Dyspepsia[NCT04684199]14 participants (Actual)Interventional2014-08-31Completed
Exploring the Mechanism of a Probiotic Combination VSL#3 in Irritable Bowel Syndrome: a Randomized Double Blind Placebo Controlled Study[NCT00786123]40 participants (Anticipated)Interventional2006-05-31Completed
Efficacy of Combination Therapy vs Placebo for Pediatric Functional Abdominal Pain[NCT01269671]Phase 10 participants (Actual)Interventional2011-01-31Withdrawn (stopped due to PI has left institution)
Melatonin and Ulcerative Colitis: A Pilot Clinical Trial[NCT00790478]Phase 23 participants (Actual)Interventional2009-01-31Terminated
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for melatonin and Abdominal Pain

ArticleYear
Melatonin for the treatment of irritable bowel syndrome.
    World journal of gastroenterology, 2014, Mar-14, Volume: 20, Issue:10

    Topics: Abdominal Pain; Animals; Dietary Supplements; Gastrointestinal Agents; Humans; Intestinal Mucosa; In

2014

Trials

7 trials available for melatonin and Abdominal Pain

ArticleYear
Randomised controlled trial of melatonin for paediatric functional abdominal pain disorders.
    Journal of paediatrics and child health, 2023, Volume: 59, Issue:3

    Topics: Abdominal Pain; Adolescent; Child; Child, Preschool; Double-Blind Method; Gastrointestinal Tract; Hu

2023
The effect of melatonin on irritable bowel syndrome patients with and without sleep disorders: a randomized double-blinded placebo-controlled trial study.
    BMC gastroenterology, 2023, Apr-25, Volume: 23, Issue:1

    Topics: Abdominal Pain; Double-Blind Method; Humans; Iran; Irritable Bowel Syndrome; Melatonin; Quality of L

2023
Influence of melatonin on symptoms of irritable bowel syndrome in postmenopausal women.
    Endokrynologia Polska, 2013, Volume: 64, Issue:2

    Topics: Abdominal Pain; Aged; Constipation; Double-Blind Method; Enzyme-Linked Immunosorbent Assay; Female;

2013
Does melatonin homeostasis play a role in continuous epigastric pain syndrome?
    International journal of molecular sciences, 2013, Jun-14, Volume: 14, Issue:6

    Topics: Abdominal Pain; Acetylserotonin O-Methyltransferase; Adult; Arylalkylamine N-Acetyltransferase; Case

2013
Melatonin improves abdominal pain in irritable bowel syndrome patients who have sleep disturbances: a randomised, double blind, placebo controlled study.
    Gut, 2005, Volume: 54, Issue:10

    Topics: Abdominal Pain; Adult; Defecation; Double-Blind Method; Female; Humans; Irritable Bowel Syndrome; Ma

2005
Melatonin improves abdominal pain in irritable bowel syndrome patients who have sleep disturbances: a randomised, double blind, placebo controlled study.
    Gut, 2005, Volume: 54, Issue:10

    Topics: Abdominal Pain; Adult; Defecation; Double-Blind Method; Female; Humans; Irritable Bowel Syndrome; Ma

2005
Melatonin improves abdominal pain in irritable bowel syndrome patients who have sleep disturbances: a randomised, double blind, placebo controlled study.
    Gut, 2005, Volume: 54, Issue:10

    Topics: Abdominal Pain; Adult; Defecation; Double-Blind Method; Female; Humans; Irritable Bowel Syndrome; Ma

2005
Melatonin improves abdominal pain in irritable bowel syndrome patients who have sleep disturbances: a randomised, double blind, placebo controlled study.
    Gut, 2005, Volume: 54, Issue:10

    Topics: Abdominal Pain; Adult; Defecation; Double-Blind Method; Female; Humans; Irritable Bowel Syndrome; Ma

2005
Melatonin improves abdominal pain in irritable bowel syndrome patients who have sleep disturbances: a randomised, double blind, placebo controlled study.
    Gut, 2005, Volume: 54, Issue:10

    Topics: Abdominal Pain; Adult; Defecation; Double-Blind Method; Female; Humans; Irritable Bowel Syndrome; Ma

2005
Melatonin improves abdominal pain in irritable bowel syndrome patients who have sleep disturbances: a randomised, double blind, placebo controlled study.
    Gut, 2005, Volume: 54, Issue:10

    Topics: Abdominal Pain; Adult; Defecation; Double-Blind Method; Female; Humans; Irritable Bowel Syndrome; Ma

2005
Melatonin improves abdominal pain in irritable bowel syndrome patients who have sleep disturbances: a randomised, double blind, placebo controlled study.
    Gut, 2005, Volume: 54, Issue:10

    Topics: Abdominal Pain; Adult; Defecation; Double-Blind Method; Female; Humans; Irritable Bowel Syndrome; Ma

2005
Melatonin improves abdominal pain in irritable bowel syndrome patients who have sleep disturbances: a randomised, double blind, placebo controlled study.
    Gut, 2005, Volume: 54, Issue:10

    Topics: Abdominal Pain; Adult; Defecation; Double-Blind Method; Female; Humans; Irritable Bowel Syndrome; Ma

2005
Melatonin improves abdominal pain in irritable bowel syndrome patients who have sleep disturbances: a randomised, double blind, placebo controlled study.
    Gut, 2005, Volume: 54, Issue:10

    Topics: Abdominal Pain; Adult; Defecation; Double-Blind Method; Female; Humans; Irritable Bowel Syndrome; Ma

2005
Melatonin improves abdominal pain in irritable bowel syndrome patients who have sleep disturbances: a randomised, double blind, placebo controlled study.
    Gut, 2005, Volume: 54, Issue:10

    Topics: Abdominal Pain; Adult; Defecation; Double-Blind Method; Female; Humans; Irritable Bowel Syndrome; Ma

2005
Melatonin improves abdominal pain in irritable bowel syndrome patients who have sleep disturbances: a randomised, double blind, placebo controlled study.
    Gut, 2005, Volume: 54, Issue:10

    Topics: Abdominal Pain; Adult; Defecation; Double-Blind Method; Female; Humans; Irritable Bowel Syndrome; Ma

2005
Melatonin improves abdominal pain in irritable bowel syndrome patients who have sleep disturbances: a randomised, double blind, placebo controlled study.
    Gut, 2005, Volume: 54, Issue:10

    Topics: Abdominal Pain; Adult; Defecation; Double-Blind Method; Female; Humans; Irritable Bowel Syndrome; Ma

2005
Melatonin improves abdominal pain in irritable bowel syndrome patients who have sleep disturbances: a randomised, double blind, placebo controlled study.
    Gut, 2005, Volume: 54, Issue:10

    Topics: Abdominal Pain; Adult; Defecation; Double-Blind Method; Female; Humans; Irritable Bowel Syndrome; Ma

2005
Melatonin improves abdominal pain in irritable bowel syndrome patients who have sleep disturbances: a randomised, double blind, placebo controlled study.
    Gut, 2005, Volume: 54, Issue:10

    Topics: Abdominal Pain; Adult; Defecation; Double-Blind Method; Female; Humans; Irritable Bowel Syndrome; Ma

2005
Melatonin improves abdominal pain in irritable bowel syndrome patients who have sleep disturbances: a randomised, double blind, placebo controlled study.
    Gut, 2005, Volume: 54, Issue:10

    Topics: Abdominal Pain; Adult; Defecation; Double-Blind Method; Female; Humans; Irritable Bowel Syndrome; Ma

2005
Melatonin improves abdominal pain in irritable bowel syndrome patients who have sleep disturbances: a randomised, double blind, placebo controlled study.
    Gut, 2005, Volume: 54, Issue:10

    Topics: Abdominal Pain; Adult; Defecation; Double-Blind Method; Female; Humans; Irritable Bowel Syndrome; Ma

2005
Therapeutic effect of melatonin in patients with functional dyspepsia.
    Journal of clinical gastroenterology, 2007, Volume: 41, Issue:3

    Topics: Abdominal Pain; Adult; Antioxidants; Cross-Over Studies; Double-Blind Method; Dyspepsia; Female; Hum

2007
Therapeutic effect of melatonin in patients with functional dyspepsia.
    Journal of clinical gastroenterology, 2007, Volume: 41, Issue:3

    Topics: Abdominal Pain; Adult; Antioxidants; Cross-Over Studies; Double-Blind Method; Dyspepsia; Female; Hum

2007
Therapeutic effect of melatonin in patients with functional dyspepsia.
    Journal of clinical gastroenterology, 2007, Volume: 41, Issue:3

    Topics: Abdominal Pain; Adult; Antioxidants; Cross-Over Studies; Double-Blind Method; Dyspepsia; Female; Hum

2007
Therapeutic effect of melatonin in patients with functional dyspepsia.
    Journal of clinical gastroenterology, 2007, Volume: 41, Issue:3

    Topics: Abdominal Pain; Adult; Antioxidants; Cross-Over Studies; Double-Blind Method; Dyspepsia; Female; Hum

2007
[The influence of melatonin on concentration of nitric oxide metabolites in gastric juice in subjects with functional dyspepsia].
    Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego, 2007, Volume: 22, Issue:131

    Topics: Abdominal Pain; Adolescent; Adult; Antioxidants; Dyspepsia; Female; Gastric Juice; Humans; Male; Mel

2007

Other Studies

4 other studies available for melatonin and Abdominal Pain

ArticleYear
The role of melatonin and cortisol circadian rhythms in the pathogenesis of infantile colic.
    World journal of pediatrics : WJP, 2018, Volume: 14, Issue:4

    Topics: Abdominal Pain; Biomarkers; Birth Weight; Case-Control Studies; Chi-Square Distribution; Circadian R

2018
Antinociceptive effects of novel melatonin receptor agonists in mouse models of abdominal pain.
    World journal of gastroenterology, 2014, Feb-07, Volume: 20, Issue:5

    Topics: Abdominal Pain; Administration, Oral; Analgesics; Animals; Behavior, Animal; Disease Models, Animal;

2014
[Irritable bowel syndrome: dietary and pharmacological therapeutic options].
    Gastroenterologie clinique et biologique, 2009, Volume: 33 Suppl 1

    Topics: Abdominal Pain; Analgesics; Anesthetics, Local; Anti-Bacterial Agents; Antidepressive Agents; Centra

2009
[Secretion of serotonin and melatonin in patients with functional dyspepsia].
    Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego, 2007, Volume: 22, Issue:131

    Topics: Abdominal Pain; Adolescent; Adult; Dyspepsia; Eating; Female; Humans; Male; Melatonin; Middle Aged;

2007