Page last updated: 2024-08-21

melarsoprol and Trypanosomiasis

melarsoprol has been researched along with Trypanosomiasis in 33 studies

Research

Studies (33)

Timeframe	Studies, this research(%)	All Research%
pre-1990	19 (57.58)	18.7374
1990's	4 (12.12)	18.2507
2000's	7 (21.21)	29.6817
2010's	3 (9.09)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Bakunov, SA; Bakunova, SM; Barszcz, T; Brun, R; Tidwell, RR; Wenzler, T; Werbovetz, KA	1
Bakunov, SA; Bakunova, SM; Barszcz, T; Bridges, AS; Brun, R; Jones, SK; Kumar, EV; Ohemeng, KA; Patrick, DA; Tidwell, RR; Wenzler, T; Werbovetz, KA	1
Baell, JB; Brun, R; Charman, WN; Fairlamb, AH; Holloway, GA; Kaiser, M; Kostewicz, E; Novello, PM; Parisot, JP; Richardson, J; Street, IP; Watson, KG	1
Bakunov, SA; Bakunova, SM; Barszcz, T; Boykin, DW; Brun, R; Jones, SK; Kumar, A; Patrick, DA; Tidwell, RR; Wenzler, T; Werbovetz, KA	1
Bucheton, B; Courtois, P; Cuny, G; Daulouède, S; Dethoua, M; Nzoumbou-Boko, R; Semballa, S; Truc, P; Vincendeau, P	1
Aguinaga Andrés, D; Baker, N; Barrett, MP; de Koning, HP; Glover, L; Horn, D; Munday, JC	1
Mpia, B; Pépin, J	1
Josenando, T; Ruiz, JA; Simarro, PP	1
CECCALDI, J	2
NEUJEAN, G	1
APTED, FI	1
PINTO, AR	1
CARMO, RP; CASEIRO, A; DE BASTO, AX; SILVA, MA	1
EVENS, F; LAMBOTTE, C; LEGRAND, J	1
BURKE, J	1
NIXON, LC; TAUBE, E	1
DE JONGH, RT; FRIEDHEIM, EA	1
ADRIA ENSSENS, K	1
JANSSENS, PG; MICHIELS, A; VAN BOGAERT, L; VAN DE STEEN, R	1
ROBERTSON, DH	2
FRIEDHEIM, EA	2
de ALMEIDA, CL; FERREIRA, FS; PIRES, FM	1
Forlenza, M; Kachamakova, NM; Rombout, JH; Scharsack, JP; Taverne-Thiele, AJ; Wiegertjes, GF	1
Auma, JE; Brun, R; Burri, C; Burudi, EM; Onyango, JD	1
Atouguia, JM; Jennings, FW; Murray, M	1
Burri, C; Keiser, J	1
Goodwin, LG; Tierney, ED	1
Astier, A; Brun-Buisson, C; Chariot, P; Gherardi, RK; Malapert, D; Schaeffer, A; Vanderstigel, M; Verroust, J	1
Cook, GC	1
van der Meer, C; Versluijs-Broers, JA	1

Trials

1 trial(s) available for melarsoprol and Trypanosomiasis

Article	Year
Combination of eflornithine and melarsoprol for melarsoprol-resistant Gambian trypanosomiasis. Tropical medicine & international health : TM & IH, 2002, Volume: 7, Issue:9 Topics: Adolescent; Adult; Congo; Drug Administration Schedule; Drug Therapy, Combination; Eflornithine; Female; Humans; Injections, Intravenous; Male; Melarsoprol; Middle Aged; Recurrence; Treatment Outcome; Trypanocidal Agents; Trypanosomiasis	2002

Article

Year

Combination of eflornithine and melarsoprol for melarsoprol-resistant Gambian trypanosomiasis.

Tropical medicine & international health : TM & IH, 2002, Volume: 7, Issue:9

Topics: Adolescent; Adult; Congo; Drug Administration Schedule; Drug Therapy, Combination; Eflornithine; Female; Humans; Injections, Intravenous; Male; Melarsoprol; Middle Aged; Recurrence; Treatment Outcome; Trypanocidal Agents; Trypanosomiasis

2002

Other Studies

32 other study(ies) available for melarsoprol and Trypanosomiasis

Article	Year
Synthesis and antiprotozoal activity of cationic 2-phenylbenzofurans. Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21 Topics: Animals; Antiprotozoal Agents; Benzofurans; Cations; Disease Models, Animal; Leishmania; Mice; Molecular Structure; Structure-Activity Relationship; Trypanosoma; Trypanosomiasis	2008
Structure-activity study of pentamidine analogues as antiprotozoal agents. Journal of medicinal chemistry, 2009, Apr-09, Volume: 52, Issue:7 Topics: Animals; Antimalarials; Cadaverine; Drug Resistance; Female; Imidazoles; Leishmania donovani; Mice; Myoblasts; Parasitic Sensitivity Tests; Pentamidine; Plasmodium falciparum; Rats; Structure-Activity Relationship; Trypanocidal Agents; Trypanosoma brucei rhodesiense; Trypanosomiasis	2009
Trypanothione reductase high-throughput screening campaign identifies novel classes of inhibitors with antiparasitic activity. Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:7 Topics: Animals; Antiparasitic Agents; Drug Evaluation, Preclinical; Humans; Microsomes, Liver; Molecular Structure; NADH, NADPH Oxidoreductases; Structure-Activity Relationship; Trypanosoma; Trypanosomiasis	2009
Synthesis and antiprotozoal activities of benzyl phenyl ether diamidine derivatives. European journal of medicinal chemistry, 2013, Volume: 67 Topics: Animals; Antiprotozoal Agents; Dose-Response Relationship, Drug; Leishmania donovani; Mice; Molecular Structure; Myoblasts; Parasitic Sensitivity Tests; Pentamidine; Phenyl Ethers; Plasmodium falciparum; Rats; Structure-Activity Relationship; Trypanosoma brucei rhodesiense; Trypanosomiasis	2013
Evaluation of trypanocidal drugs used for human African trypanosomosis against Trypanosoma lewisi. Parasite (Paris, France), 2013, Volume: 20 Topics: Animals; Eflornithine; Female; Humans; Immunocompromised Host; Inhibitory Concentration 50; Melarsoprol; Mice; Nifurtimox; Nitroimidazoles; Parasitemia; Pentamidine; Rats; Rats, Wistar; Suramin; Trypanocidal Agents; Trypanosoma lewisi; Trypanosomiasis	2013
Aquaglyceroporin 2 controls susceptibility to melarsoprol and pentamidine in African trypanosomes. Proceedings of the National Academy of Sciences of the United States of America, 2012, Jul-03, Volume: 109, Issue:27 Topics: Animals; Aquaporin 2; Aquaporin 3; Cell Line; Drug Resistance; Flagella; High-Throughput Screening Assays; Humans; Melarsoprol; Molecular Sequence Data; Pentamidine; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis; Tsetse Flies	2012
Control of human African trypanosomiasis in the Quiçama focus, Angola. Bulletin of the World Health Organization, 2002, Volume: 80, Issue:9 Topics: Angola; Communicable Disease Control; Endemic Diseases; Humans; Melarsoprol; Pentamidine; Risk Factors; Seroepidemiologic Studies; Treatment Failure; Trypanocidal Agents; Trypanosomiasis	2002
[Arsobal therapy (3854 R.P.) of trypanosomiasis in early stages]. Bulletin de la Societe de pathologie exotique et de ses filiales, 1952, Volume: 45, Issue:5 Topics: Humans; Melarsoprol; Trypanosomiasis	1952
[New contribution on arsobal (R.P. 3854) therapy of trypanosomiasis; its effectiveness in former trypanosomiasis patients, with meningoencephalitis, resistant to trypanocides customarily used]. Bulletin de la Societe de pathologie exotique et de ses filiales, 1953, Volume: 46, Issue:1 Topics: Animals; Arsenicals; Humans; Melarsoprol; Meningoencephalitis; Trypanocidal Agents; Trypanosomiasis	1953
[Use of arsobal in the treatment of sleeping sickness]. Anais do Instituto de Medicina Tropical, 1952, Volume: 9, Issue:3 Topics: Animals; Arsenicals; Black People; Humans; Melarsoprol; Trypanosomiasis; Trypanosomiasis, African	1952
The treatment of advanced cases of Rhodesian sleeping sickness by Mel. B. and arsobal. Transactions of the Royal Society of Tropical Medicine and Hygiene, 1953, Volume: 47, Issue:5 Topics: Animals; Arsenicals; Black People; Humans; Melarsoprol; Trypanosomiasis; Trypanosomiasis, African	1953
The therapeutic effect on a group of sleeping sickness patients of a single injection of 3854 R.P. (mel B Friedheim-arsobal Spécia). The American journal of tropical medicine and hygiene, 1954, Volume: 3, Issue:3 Topics: Animals; Arsenicals; Humans; Melarsoprol; Trypanosomiasis; Trypanosomiasis, African	1954
Arsobal in the treatment of Rhodesian sleeping-sickness. Anais do Instituto de Medicina Tropical, 1954, Volume: 11, Issue:2 Topics: Animals; Arsenicals; Humans; Melarsoprol; Trypanosomiasis; Trypanosomiasis, African	1954
[A case of trypanosomiasis in an infant treated with arsobal]. Annales de la Societe belge de medecine tropicale (1920), 1956, Oct-31, Volume: 36, Issue:5 Topics: Animals; Arsenicals; Child; Humans; Infant; Melarsoprol; Trypanosomiasis	1956
[Study of the therapeutic value of arsobal in trypanosomiasis caused by Trypanosoma gambiense]. Annales de la Societe belge de medecine tropicale (1920), 1957, Apr-30, Volume: 37, Issue:2 Topics: Animals; Arsenicals; Black People; Humans; Melarsoprol; Trypanosoma brucei gambiense; Trypanosomiasis; Trypanosomiasis, African	1957
The treatment of advanced trypanosomiasis rhodesiense with mel B. The Central African journal of medicine, 1958, Volume: 4, Issue:4 Topics: Animals; Arsenicals; Black People; Humans; Melarsoprol; Trypanosomiasis; Trypanosomiasis, African	1958
Mel W, a new trypanosomicidal agent derived from mel B. Transactions of the Royal Society of Tropical Medicine and Hygiene, 1959, Volume: 53, Issue:3 Topics: Arsenicals; Humans; Melarsoprol; Trypanocidal Agents; Trypanosomiasis	1959
[Note on the toxicity of MEL B in Trypanosoma rhodesiense sleeping sickness]. Annales de la Societe belge de medecine tropicale (1920), 1960, Aug-31, Volume: 40 Topics: Animals; Black People; Humans; Melarsoprol; Trypanosoma brucei rhodesiense; Trypanosomiasis; Trypanosomiasis, African	1960
[African trypanosomiasis, virus disease, Mel B and encephalitis]. Annales de la Societe belge de medecine tropicale (1920), 1960, Oct-31, Volume: 40 Topics: Animals; Arsenic Poisoning; Coxsackievirus Infections; Encephalitis; Enterovirus; Humans; Infections; Melarsoprol; Trypanosomiasis; Trypanosomiasis, African; Virus Diseases	1960
The treatment of sleeping sickness (mainly due to Trypanosoma rhodesiense) with melarsoprol. I. Reactions observed during treatment. Transactions of the Royal Society of Tropical Medicine and Hygiene, 1963, Volume: 57 Topics: Animals; Arsenicals; Dimercaprol; Humans; Melarsoprol; Trypanosoma brucei rhodesiense; Trypanosomiasis; Trypanosomiasis, African	1963
The treatment of sleeping sickness (mainly due to Trypanosoma rhodesiense) with melarsoprol. Transactions of the Royal Society of Tropical Medicine and Hygiene, 1963, Volume: 57 Topics: Animals; Arsenicals; Dimercaprol; Humans; Melarsoprol; Trypanosoma brucei rhodesiense; Trypanosomiasis; Trypanosomiasis, African	1963
Mel B in the treatment of tryparsamide resistant T. gambiense sleeping sickness: observations on drug resistance in the trypanosomes of the French Cameroun. The American journal of tropical medicine and hygiene, 1951, Volume: 31, Issue:2 Topics: Animals; Arsenic; Arsenicals; Drug Resistance; Humans; Melarsoprol; Trypanosomiasis; Trypanosomiasis, African	1951
[First results of the treatment of human trypanosomiasis with Mel B]. Anais do Instituto de Medicina Tropical, 1950, Volume: 7 Topics: Arsenic; Humans; Melarsoprol; Trypanosomiasis	1950
Mel B in the treatment of human trypanosomiasis. The American journal of tropical medicine and hygiene, 1949, Volume: 29, Issue:2 Topics: Melarsoprol; Trypanosomiasis	1949
Differential contribution of neutrophilic granulocytes and macrophages to nitrosative stress in a host-parasite animal model. Molecular immunology, 2008, Volume: 45, Issue:11 Topics: Animals; B-Lymphocytes; Carps; Cell Death; Gene Expression Regulation, Enzymologic; Host-Parasite Interactions; Macrophages; Melarsoprol; Models, Animal; Neutrophils; Nitric Oxide; Nitric Oxide Synthase Type II; Nitrites; Parasitemia; Parasites; Peroxidase; Peroxynitrous Acid; Reactive Nitrogen Species; Spleen; Stress, Physiological; Trypanosoma; Trypanosomiasis; Tyrosine	2008
Pharmacokinetics of melarsoprol in uninfected vervet monkeys. Acta tropica, 1994, Volume: 58, Issue:1 Topics: Animals; Chlorocebus aethiops; Drug Administration Schedule; Half-Life; Humans; Injections, Intravenous; Male; Melarsoprol; Metabolic Clearance Rate; Species Specificity; Trypanosomiasis	1994
Topical melarsoprol for trypanosomiasis. Lancet (London, England), 1993, May-22, Volume: 341, Issue:8856 Topics: Administration, Cutaneous; Animals; Humans; Melarsoprol; Mice; Trypanosomiasis	1993
Physico-chemical properties of the trypanocidal drug melarsoprol. Acta tropica, 2000, Jan-05, Volume: 74, Issue:1 Topics: Humans; Melarsoprol; Molecular Structure; Protein Binding; Trypanocidal Agents; Trypanosomiasis	2000
Trypanocidal activity of blood and tissue fluid from normal and infected rabbits treated with curative drugs. Parasitology, 1977, Volume: 74, Issue:1 Topics: Animals; Benzamidines; Body Fluids; Diminazene; Ethidium; Male; Melarsoprol; Mice; Phenanthridines; Rabbits; Suramin; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis	1977
Organic arsenic-induced Guillain-Barré-like syndrome due to melarsoprol: a clinical, electrophysiological, and pathological study. Muscle & nerve, 1990, Volume: 13, Issue:7 Topics: Adult; Arsenic; Arsenic Poisoning; Arsenicals; Diagnosis, Differential; Electrophysiology; Female; Humans; Melarsoprol; Peripheral Nervous System Diseases; Polyradiculoneuropathy; Trypanosomiasis	1990
'Exotic' parasitic infections: recent progress in diagnosis and management. The Journal of infection, 1990, Volume: 20, Issue:2 Topics: Animals; Antiprotozoal Agents; Diethylcarbamazine; Filariasis; Humans; Leishmaniasis; Melarsoprol; Serologic Tests; Trypanosomiasis	1990
Trypanosoma brucei and T. vivax: salicylhydroxamic acid and glycerol treatment of acute and chronically infected rats. Experimental parasitology, 1986, Volume: 62, Issue:1 Topics: Animals; Brain; Drug Administration Schedule; Drug Therapy, Combination; Female; Glycerol; Melarsoprol; Mice; Muscles; Rats; Rats, Inbred Strains; Salicylamides; Suramin; Trypanocidal Agents; Trypanosoma; Trypanosoma brucei brucei; Trypanosomiasis; Trypanosomiasis, African	1986