Page last updated: 2024-08-21

melarsoprol and Recrudescence

melarsoprol has been researched along with Recrudescence in 27 studies

Research

Studies (27)

TimeframeStudies, this research(%)All Research%
pre-19905 (18.52)18.7374
1990's3 (11.11)18.2507
2000's14 (51.85)29.6817
2010's5 (18.52)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kaka, JT; Kazumba, LM; Ngoyi, DM; Tshala-Katumbay, D1
Kennedy, A; Lutje, V; Seixas, J2
Büscher, P; Karhemere Bin Shamamba, S; Mumba Ngoyi, D; Ngay Lukusa, I; Pyana Pati, P; Van Reet, N1
Betu Ku Mesu Kande, V; Boelaert, M; Lutumba, P; Nyamowala, G; Robays, J; Sese, C; Van der Veken, W1
Büscher, P; Kaiser, M; Karhemere Bin Shamamba, S; Mumba Ngoyi, D; Ngay Lukusa, I; Pyana, PP; Van Reet, N1
Mpia, B; Pépin, J2
Kager, PA; Mendonça Melo, M; Rasica, M; Richter, C; van Thiel, PP; Wismans, PJ1
Boa, F; Dje, NN; Doua, F; Miezan, TW1
Büscher, P; Etchegorry, MG; Legros, D; Lejon, V; Mbulamberi, D; Savignoni, A1
Kaboya, JS; Kibona, SN; Lubega, GW; Matemba, L1
Franco, JR; Jannin, J; Louis, FJ; Ndongo, P; Nguema, E; Simarro, PP1
Bisser, S; Būscher, P; Lejon, V; Miaka Mia Bilenge, C; N'Siesi, FX; Preux, PM; Van Nieuwenhove, S1
Checkley, AM; Gibson, WC; Jäger, HR; Mabey, DC; Pepin, J; Taylor, MN1
Abel, PM; Krishna, S; Woodrow, CJ1
Poltera, AA1
Boa Yapo, F; Doua, F1
Doua, F; Yapo, FB1
Bouteille, B; Dumas, M1
Enyaru, JC; Kaminsky, R; Legros, D; Matovu, E; Schmid, C; Seebeck, T1
Enyaru, JC; Gallati, S; Geiser, F; Kaminsky, R; Mäser, P; Matovu, E; Schneider, V; Seebeck, T1
Brun, R; Burri, C; Kunz, C; Schmid, C; Schumacher, R1
Bales, JD; Harrison, SM; Mbwabi, DL; Schecter, PJ1
Abinya, A; Chumo, DA; Dola, S; Mbwabi, D; Reardon, MJ; Siongok, TA; Smith, DH; Wanyama, L; Wellde, BT1
Guern, C; Milord, F; Pepin, J; Schechter, PJ1
Champalimaud, JL; Medina, EA; Ventura, FA1

Reviews

3 review(s) available for melarsoprol and Recrudescence

ArticleYear
Chemotherapy for second-stage human African trypanosomiasis.
    The Cochrane database of systematic reviews, 2013, Jun-28, Issue:6

    Topics: Animals; Antiprotozoal Agents; Drug Therapy, Combination; Eflornithine; Humans; Melarsoprol; Nifurtimox; Pentamidine; Prednisolone; Randomized Controlled Trials as Topic; Recurrence; Trypanosoma brucei gambiense; Trypanosomiasis, African

2013
Chemotherapy for second-stage Human African trypanosomiasis.
    The Cochrane database of systematic reviews, 2010, Aug-04, Issue:8

    Topics: Animals; Antiprotozoal Agents; Drug Therapy, Combination; Eflornithine; Humans; Melarsoprol; Nifurtimox; Pentamidine; Prednisolone; Randomized Controlled Trials as Topic; Recurrence; Trypanosoma brucei gambiense; Trypanosomiasis, African

2010
Human trypanosomiasis in the Ivory Coast: therapy and problems.
    Acta tropica, 1993, Volume: 54, Issue:3-4

    Topics: Animals; Cote d'Ivoire; Eflornithine; Humans; Melarsoprol; Pentamidine; Recurrence; Trypanosoma brucei gambiense; Trypanosomiasis, African

1993

Trials

4 trial(s) available for melarsoprol and Recrudescence

ArticleYear
Combination of eflornithine and melarsoprol for melarsoprol-resistant Gambian trypanosomiasis.
    Tropical medicine & international health : TM & IH, 2002, Volume: 7, Issue:9

    Topics: Adolescent; Adult; Congo; Drug Administration Schedule; Drug Therapy, Combination; Eflornithine; Female; Humans; Injections, Intravenous; Male; Melarsoprol; Middle Aged; Recurrence; Treatment Outcome; Trypanocidal Agents; Trypanosomiasis

2002
Neuro-inflammatory risk factors for treatment failure in "early second stage" sleeping sickness patients treated with pentamidine.
    Journal of neuroimmunology, 2003, Volume: 144, Issue:1-2

    Topics: Adolescent; Adult; Animals; Cerebrospinal Fluid Proteins; Child; Child, Preschool; Female; Humans; Immunoglobulin M; Latex Fixation Tests; Leukocyte Count; Male; Melarsoprol; Middle Aged; Pentamidine; Recurrence; Risk Factors; Treatment Failure; Trypanosoma brucei gambiense; Trypanosomiasis, African

2003
Randomized controlled trial of three regimens of melarsoprol in the treatment of Trypanosoma brucei gambiense trypanosomiasis.
    Transactions of the Royal Society of Tropical Medicine and Hygiene, 2006, Volume: 100, Issue:5

    Topics: Adolescent; Adult; Animals; Drug Administration Schedule; Female; Humans; Leukocyte Count; Lymph Nodes; Male; Melarsoprol; Proportional Hazards Models; Recurrence; Trypanocidal Agents; Trypanosoma brucei gambiense; Trypanosomiasis, African

2006
Equivalence trial of melarsoprol and nifurtimox monotherapy and combination therapy for the treatment of second-stage Trypanosoma brucei gambiense sleeping sickness.
    The Journal of infectious diseases, 2007, Feb-01, Volume: 195, Issue:3

    Topics: Administration, Oral; Adult; Animals; Brain Diseases; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Injections, Intravenous; Male; Melarsoprol; Nifurtimox; Recurrence; Treatment Outcome; Trypanocidal Agents; Trypanosoma brucei gambiense; Trypanosomiasis, African

2007

Other Studies

20 other study(ies) available for melarsoprol and Recrudescence

ArticleYear
Mortality trends and risk factors in advanced stage-2 Human African Trypanosomiasis: A critical appraisal of 23 years of experience in the Democratic Republic of Congo.
    PLoS neglected tropical diseases, 2018, Volume: 12, Issue:6

    Topics: Adolescent; Adult; Democratic Republic of the Congo; Disease Management; Drug Therapy, Combination; Eflornithine; Female; Hospital Records; Humans; Male; Melarsoprol; Middle Aged; Multivariate Analysis; Nifurtimox; Recurrence; Retrospective Studies; Risk Factors; Treatment Outcome; Trypanocidal Agents; Trypanosoma brucei gambiense; Trypanosomiasis, African; Young Adult

2018
Melarsoprol sensitivity profile of Trypanosoma brucei gambiense isolates from cured and relapsed sleeping sickness patients from the Democratic Republic of the Congo.
    PLoS neglected tropical diseases, 2014, Volume: 8, Issue:10

    Topics: Adult; Animals; Aquaglyceroporins; Base Sequence; Democratic Republic of the Congo; DNA, Protozoan; Drug Resistance; Female; Genotype; Humans; Melarsoprol; Mice; Molecular Sequence Data; Mutant Chimeric Proteins; Mutation; Pentamidine; Phenotype; Recurrence; Sequence Analysis, DNA; Trypanocidal Agents; Trypanosoma brucei gambiense; Trypanosomiasis, African

2014
High failure rates of melarsoprol for sleeping sickness, Democratic Republic of Congo.
    Emerging infectious diseases, 2008, Volume: 14, Issue:6

    Topics: Adolescent; Adult; Animals; Child; Child, Preschool; Democratic Republic of the Congo; Female; Humans; Infant; Male; Melarsoprol; Middle Aged; Recurrence; Treatment Failure; Trypanocidal Agents; Trypanosomiasis, African

2008
Isolation of Trypanosoma brucei gambiense from cured and relapsed sleeping sickness patients and adaptation to laboratory mice.
    PLoS neglected tropical diseases, 2011, Apr-19, Volume: 5, Issue:4

    Topics: Adaptation, Biological; Animals; Antiprotozoal Agents; Blood; Cerebrospinal Fluid; Female; Humans; Male; Melarsoprol; Mice; Recurrence; Trypanosoma brucei gambiense; Trypanosomiasis, African

2011
[Three patients with African sleeping sickness following a visit to Tanzania].
    Nederlands tijdschrift voor geneeskunde, 2002, Dec-28, Volume: 146, Issue:52

    Topics: Africa; Animals; Fatal Outcome; Female; Humans; Male; Melarsoprol; Middle Aged; Netherlands; Recurrence; Tanzania; Travel; Trypanocidal Agents; Trypanosoma brucei gambiense; Trypanosoma brucei rhodesiense; Trypanosomiasis, African

2002
[Human African trypanosomiasis in Ivory Coast: biological characteristics after treatment. 812 cases treated in the Daloa focus (Ivory Coast)].
    Bulletin de la Societe de pathologie exotique (1990), 2002, Volume: 95, Issue:5

    Topics: Animals; Antibodies, Protozoan; Cerebrospinal Fluid; Cerebrospinal Fluid Proteins; Cote d'Ivoire; Follow-Up Studies; Humans; Melarsoprol; Recurrence; Severity of Illness Index; Time Factors; Treatment Outcome; Trypanocidal Agents; Trypanosoma brucei gambiense; Trypanosomiasis, African

2002
Drug-resistance of Trypanosoma b. rhodesiense isolates from Tanzania.
    Tropical medicine & international health : TM & IH, 2006, Volume: 11, Issue:2

    Topics: Animals; Diminazene; Drug Resistance; Humans; Mass Screening; Melarsoprol; Phenanthridines; Recurrence; Suramin; Tanzania; Trypanocidal Agents; Trypanosoma brucei rhodesiense; Trypanosomiasis, African

2006
The elimination of Trypanosoma brucei gambiense sleeping sickness in the focus of Luba, Bioko Island, Equatorial Guinea.
    Tropical medicine & international health : TM & IH, 2006, Volume: 11, Issue:5

    Topics: Agglutination Tests; Animals; Disease Outbreaks; Disease Vectors; Endemic Diseases; Equatorial Guinea; Fluorescent Antibody Technique, Indirect; Humans; Melarsoprol; Pentamidine; Population Surveillance; Prevalence; Recurrence; Rural Health; Trypanocidal Agents; Trypanosoma brucei gambiense; Trypanosomiasis, African

2006
Human African trypanosomiasis: diagnosis, relapse and survival after severe melarsoprol-induced encephalopathy.
    Transactions of the Royal Society of Tropical Medicine and Hygiene, 2007, Volume: 101, Issue:5

    Topics: Adult; Animals; Brain Diseases; Humans; Magnetic Resonance Imaging; Male; Melarsoprol; Polymerase Chain Reaction; Recurrence; Trypanocidal Agents; Trypanosoma brucei rhodesiense; Trypanosomiasis, African

2007
Randomized, controlled trial of treatments for second-stage sleeping sickness.
    The Journal of infectious diseases, 2007, Aug-15, Volume: 196, Issue:4

    Topics: Animals; Drug Therapy, Combination; Humans; Melarsoprol; Nifurtimox; Randomized Controlled Trials as Topic; Recurrence; Treatment Failure; Treatment Outcome; Trypanocidal Agents; Trypanosoma brucei gambiense; Trypanosomiasis, African

2007
Chemotherapy, relapses and CNS in experimental African trypanosomiasis.
    Contributions to microbiology and immunology, 1983, Volume: 7

    Topics: Animals; Central Nervous System; Chlorocebus aethiops; Chloroquine; Melarsoprol; Mice; Recurrence; Trypanosoma brucei brucei; Trypanosomiasis, African

1983
[Current therapy of trypanosomiasis].
    Bulletin de la Societe de pathologie exotique (1990), 1994, Volume: 87, Issue:5

    Topics: Adenosylmethionine Decarboxylase; Animals; Arsenicals; Deoxyadenosines; Drug Resistance; Eflornithine; Enzyme Inhibitors; Hospitalization; Humans; Melarsoprol; Pentamidine; Randomized Controlled Trials as Topic; Recurrence; Suramin; Triazines; Trypanocidal Agents; Trypanosomiasis, African

1994
[Current status of trypanosomiasis].
    Medecine tropicale : revue du Corps de sante colonial, 1997, Volume: 57, Issue:3 Suppl

    Topics: Africa; Animals; Autoantibodies; Blood-Brain Barrier; Brain Diseases; Follow-Up Studies; Forecasting; Humans; Incidence; Melarsoprol; Nitroimidazoles; Pentamidine; Population Surveillance; Protozoan Vaccines; Recurrence; Social Problems; Socioeconomic Factors; Survival Rate; Trypanocidal Agents; Trypanosoma; Trypanosomiasis, African

1997
Melarsoprol refractory T. b. gambiense from Omugo, north-western Uganda.
    Tropical medicine & international health : TM & IH, 2001, Volume: 6, Issue:5

    Topics: Animals; DNA, Protozoan; Drug Resistance; Eflornithine; Humans; Melarsoprol; Microbial Sensitivity Tests; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Recurrence; Treatment Outcome; Trypanocidal Agents; Trypanosoma brucei gambiense; Trypanosomiasis, African; Uganda

2001
Genetic variants of the TbAT1 adenosine transporter from African trypanosomes in relapse infections following melarsoprol therapy.
    Molecular and biochemical parasitology, 2001, Sep-28, Volume: 117, Issue:1

    Topics: Adenosine; Animals; Carrier Proteins; Cerebrospinal Fluid; Drug Resistance; Genetic Variation; Humans; Melarsoprol; Mutation; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Polymorphism, Single-Stranded Conformational; Recurrence; Sequence Analysis, DNA; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African

2001
The phenomenon of treatment failures in Human African Trypanosomiasis.
    Tropical medicine & international health : TM & IH, 2001, Volume: 6, Issue:11

    Topics: Africa, Eastern; Animals; Dose-Response Relationship, Drug; Drug Resistance; Humans; Melarsoprol; Mice; Muridae; Parasitic Sensitivity Tests; Recurrence; Treatment Failure; Trypanocidal Agents; Trypanosoma brucei gambiense; Trypanosoma brucei rhodesiense; Trypanosomiasis, African

2001
Treatment of arsenical refractory Rhodesian sleeping sickness in Kenya.
    Annals of tropical medicine and parasitology, 1989, Volume: 83 Suppl 1

    Topics: Adult; Animals; Arsenicals; Drug Therapy, Combination; Eflornithine; Female; Humans; Kenya; Male; Melarsoprol; Middle Aged; Recurrence; Suramin; Trypanosoma brucei brucei; Trypanosomiasis, African

1989
Treatment of Rhodesian sleeping sickness in Kenya.
    Annals of tropical medicine and parasitology, 1989, Volume: 83 Suppl 1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Animals; Arsenicals; Child; Drug Resistance; Female; Follow-Up Studies; Humans; Kenya; Male; Melarsoprol; Middle Aged; Prospective Studies; Recurrence; Retrospective Studies; Suramin; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African

1989
Difluoromethylornithine for arseno-resistant Trypanosoma brucei gambiense sleeping sickness.
    Lancet (London, England), 1987, Dec-19, Volume: 2, Issue:8573

    Topics: Administration, Oral; Adolescent; Animals; Arsenicals; Child; Child, Preschool; Diarrhea; Drug Resistance; Eflornithine; Female; Follow-Up Studies; Humans; Infusions, Intravenous; Male; Melarsoprol; Recurrence; Trypanosoma brucei gambiense; Trypanosomiasis, African

1987
Computer-assisted tomographic findings in a patient with African trypanosomiasis.
    The Journal of tropical medicine and hygiene, 1986, Volume: 89, Issue:2

    Topics: Brain Diseases; Child, Preschool; Diminazene; Humans; Male; Melarsoprol; Meningoencephalitis; Recurrence; Tomography, X-Ray Computed; Trypanosomiasis, African

1986