melarsoprol has been researched along with Disease Models, Animal in 21 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 2 (9.52) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 5 (23.81) | 29.6817 |
2010's | 13 (61.90) | 24.3611 |
2020's | 1 (4.76) | 2.80 |
Authors | Studies |
---|---|
Bakunov, SA; Bakunova, SM; Barszcz, T; Brun, R; Tidwell, RR; Wenzler, T; Werbovetz, KA | 1 |
Bakunov, SA; Bakunova, SM; Brun, R; Ghebru, M; Tidwell, RR; Wenzler, T; Werbovetz, KA | 1 |
Brun, R; Jędrysiak, R; Kaiser, M; Suwiński, J; Torreele, E; Trunz, BB; Tweats, D | 1 |
Brun, R; Faist, J; Kaiser, M; Saf, R; Seebacher, W; Weis, R | 1 |
Cal, M; Dong, Y; Kaiser, M; Vennerstrom, JL; Wang, X | 1 |
Dardonville, C; Kaiser, M; Lagartera, L; Ríos Martínez, CH | 1 |
Battistuzzi, G; Giannini, G | 1 |
Battistuzzi, G; Giannini, G; Vignola, D | 1 |
Brantner, A; Brun, R; Bucar, F; Faist, J; Gröblacher, B; Kaiser, M; Kalia, Y; Merino, V; Perozzo, R; Saf, R; Scapozza, L; Seebacher, W; Weis, R; Wolkinger, V | 1 |
Bloomer, WD; Chatelain, E; Ioset, JR; Kaiser, M; O'Shea, IP; Papadopoulou, MV; Rosenzweig, HS; Wilkinson, SR | 1 |
Auma, JE; Chemuliti, JK; Gitonga, PK; Kurgat, RK; Mdachi, RE; Murilla, GA; Ndung'u, K; Ngae, GN; Thuita, JK; Thungu, DK | 1 |
Baker, N; Horn, D; Jeacock, L; Mäser, P; Wiedemar, N | 1 |
Bradley, B; Burrell-Saward, H; Croft, SL; Rodgers, J; Ward, TH | 1 |
De Koning, HP; Dogruel, M; Rodgers, J; Sanderson, L; Thomas, SA | 1 |
Farah, IO; Hau, J; Kagira, JM; Kariuki, C; Maina, N; Mwangangi, DM; Ngotho, M; Thuita, JK | 1 |
Barrett, MP; Bradley, B; Gettinby, G; Gibaud, S; Jones, A; Kennedy, PG; McCabe, C; Rodgers, J | 1 |
Bradley, B; Kennedy, PG; Rodgers, J | 1 |
Poltera, AA | 1 |
Burri, C; Ericsson, O; Keiser, J | 1 |
Jennings, F; Kennedy, PG; Murray, M; Rodgers, J | 1 |
Bouteille, B; Darde, ML; Monteil, J; Pestre-Alexandre, M | 1 |
21 other study(ies) available for melarsoprol and Disease Models, Animal
Article | Year |
---|---|
Synthesis and antiprotozoal activity of cationic 2-phenylbenzofurans.
Topics: Animals; Antiprotozoal Agents; Benzofurans; Cations; Disease Models, Animal; Leishmania; Mice; Molecular Structure; Structure-Activity Relationship; Trypanosoma; Trypanosomiasis | 2008 |
Synthesis and antiprotozoal activity of cationic 1,4-diphenyl-1H-1,2,3-triazoles.
Topics: Amidines; Animals; Antiprotozoal Agents; Cell Line; Cell Survival; Disease Models, Animal; Female; Leishmania donovani; Mice; Molecular Structure; Parasitic Sensitivity Tests; Plasmodium falciparum; Rats; Stereoisomerism; Structure-Activity Relationship; Triazoles; Trypanosoma brucei rhodesiense | 2010 |
1-Aryl-4-nitro-1H-imidazoles, a new promising series for the treatment of human African trypanosomiasis.
Topics: Animals; Antiprotozoal Agents; Cell Survival; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Humans; Leukocytes, Mononuclear; Mice; Molecular Structure; Mutagenicity Tests; Nitroimidazoles; Oxidation-Reduction; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship; Trypanosomiasis, African | 2011 |
Antiprotozoal activity of bicyclic diamines with a N-methylpiperazinyl group at the bridgehead atom.
Topics: Animals; Antiprotozoal Agents; Bridged Bicyclo Compounds; Cell Line; Cell Survival; Disease Models, Animal; Female; Mice; Parasitic Sensitivity Tests; Piperazine; Piperazines; Plasmodium falciparum; Rats; Structure-Activity Relationship; Trypanosoma brucei rhodesiense | 2013 |
Activity of diimidazoline amides against African trypanosomiasis.
Topics: Amides; Animals; Disease Models, Animal; Humans; Imidazolines; Mice; Molecular Structure; Trypanocidal Agents; Trypanosoma; Trypanosomiasis, African | 2014 |
Antiprotozoal activity and DNA binding of N-substituted N-phenylbenzamide and 1,3-diphenylurea bisguanidines.
Topics: Animals; Antiparasitic Agents; Benzamides; Binding Sites; Cell Line; Cell Survival; Disease Models, Animal; DNA; Dose-Response Relationship, Drug; Female; Guanidines; Mice; Mice, Inbred Strains; Molecular Structure; Parasitic Sensitivity Tests; Plasmodium falciparum; Rats; Structure-Activity Relationship; Surface Plasmon Resonance; Trypanosoma brucei rhodesiense; Trypanosomiasis, African; Urea | 2014 |
Exploring in vitro and in vivo Hsp90 inhibitors activity against human protozoan parasites.
Topics: Animals; Antiprotozoal Agents; Cell Line, Tumor; Disease Models, Animal; HSP90 Heat-Shock Proteins; Humans; Mice; Parasitemia; Plasmodium falciparum; Protein Binding; Rats; Triazoles; Trypanosoma brucei rhodesiense | 2015 |
Hydroxamic acid based histone deacetylase inhibitors with confirmed activity against the malaria parasite.
Topics: Animals; Antimalarials; Cell Line, Tumor; Dipeptides; Disease Models, Animal; Histone Deacetylase Inhibitors; Histone Deacetylases; Humans; Hydroxamic Acids; Malaria; Mice; Parasites; Plasmodium falciparum; Protein Isoforms | 2015 |
Synthesis of 3-azabicyclo[3.2.2]nonanes and their antiprotozoal activities.
Topics: Administration, Oral; Animals; Antiprotozoal Agents; Azabicyclo Compounds; Disease Models, Animal; Dose-Response Relationship, Drug; Injections, Intravenous; Male; Mice; Molecular Structure; Parasitic Sensitivity Tests; Plasmodium berghei; Plasmodium falciparum; Rats; Structure-Activity Relationship; Tissue Distribution; Trypanosoma brucei rhodesiense; Trypanosomiasis, African | 2015 |
Discovery of potent nitrotriazole-based antitrypanosomal agents: In vitro and in vivo evaluation.
Topics: Animals; Binding Sites; Cell Line; Chagas Disease; Disease Models, Animal; Leishmania donovani; Mice; Mice, Inbred BALB C; Nitroreductases; Parasitic Sensitivity Tests; Prodrugs; Protein Structure, Tertiary; Protozoan Proteins; Rats; Sterol 14-Demethylase; Structure-Activity Relationship; Triazoles; Trypanocidal Agents; Trypanosoma brucei rhodesiense; Trypanosoma cruzi | 2015 |
Differential virulence of Trypanosoma brucei rhodesiense isolates does not influence the outcome of treatment with anti-trypanosomal drugs in the mouse model.
Topics: Animals; Diminazene; Disease Models, Animal; Drug Resistance; Kenya; Male; Melarsoprol; Mice; Pentamidine; Suramin; Treatment Outcome; Trypanocidal Agents; Trypanosoma brucei rhodesiense; Trypanosomiasis, African; Uganda; Virulence | 2020 |
Aquaglyceroporin-null trypanosomes display glycerol transport defects and respiratory-inhibitor sensitivity.
Topics: Animals; Aquaglyceroporins; Biological Transport; Disease Models, Animal; Drug Resistance; Gene Knockout Techniques; Glycerol; Melarsoprol; Mice; Mice, Inbred BALB C; Trypanocidal Agents; Trypanosoma brucei gambiense; Trypanosomiasis, African | 2017 |
A sensitive and reproducible in vivo imaging mouse model for evaluation of drugs against late-stage human African trypanosomiasis.
Topics: Animals; Diagnostic Imaging; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Humans; Luminescent Measurements; Melarsoprol; Mice; Parasite Load; Reproducibility of Results; Sensitivity and Specificity; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African | 2015 |
Pentamidine movement across the murine blood-brain and blood-cerebrospinal fluid barriers: effect of trypanosome infection, combination therapy, P-glycoprotein, and multidrug resistance-associated protein.
Topics: Adenine; Adenosine; Animals; ATP Binding Cassette Transporter, Subfamily B; Biological Transport; Blood-Brain Barrier; Brain; Cerebrospinal Fluid; Disease Models, Animal; Drug Interactions; Eflornithine; Indomethacin; Male; Melarsoprol; Mice; Mice, Inbred BALB C; Mice, Inbred Strains; Mice, Knockout; Multidrug Resistance-Associated Proteins; Nifurtimox; Pentamidine; Perfusion; Suramin; Trypanosoma brucei brucei; Trypanosomiasis, African | 2009 |
Influence of trypanocidal therapy on the haematology of vervet monkeys experimentally infected with Trypanosoma brucei rhodesiense.
Topics: Anemia, Macrocytic; Animals; Blood Platelets; Cerebrospinal Fluid; Chlorocebus aethiops; Diminazene; Disease Models, Animal; Female; Hematology; Leukocytes; Male; Melarsoprol; Thrombocytopenia; Trypanosoma brucei rhodesiense; Trypanosomiasis, African | 2011 |
Melarsoprol cyclodextrin inclusion complexes as promising oral candidates for the treatment of human African trypanosomiasis.
Topics: Administration, Oral; Africa South of the Sahara; Animals; Antiprotozoal Agents; Blood-Brain Barrier; Brain; Cyclodextrins; Disease Models, Animal; Humans; Magnetic Resonance Imaging; Male; Melarsoprol; Mice; Models, Molecular; Molecular Structure; Parasite Load; Parasitic Sensitivity Tests; Radiography; Treatment Outcome; Trypanosoma brucei brucei; Trypanosomiasis, African | 2011 |
Combination chemotherapy with a substance P receptor antagonist (aprepitant) and melarsoprol in a mouse model of human African trypanosomiasis.
Topics: Animals; Aprepitant; Disease Models, Animal; Drug Therapy, Combination; Humans; Melarsoprol; Mice; Morpholines; Neurokinin-1 Receptor Antagonists; Treatment Outcome; Trypanocidal Agents; Trypanosomiasis, African | 2007 |
Immunopathological and chemotherapeutic studies in experimental trypanosomiasis with special reference to the heart and brain.
Topics: Animals; Brain; Disease Models, Animal; Ethidium; Female; Humans; Melarsoprol; Mice; Myocardium; Time Factors; Trypanosoma brucei brucei; Trypanosomiasis, African | 1980 |
Investigations of the metabolites of the trypanocidal drug melarsoprol.
Topics: Adult; Animals; Area Under Curve; Arsenic; Arsenicals; Biological Assay; Chromatography, High Pressure Liquid; Disease Models, Animal; Drug Interactions; Female; Humans; Male; Melarsoprol; Mice; Mice, Inbred Strains; Microsomes, Liver; Spectrophotometry, Atomic; Trypanocidal Agents; Trypanosoma brucei gambiense; Trypanosomiasis, African | 2000 |
Sleeping sickness: new drugs from old? [corrected].
Topics: Africa South of the Sahara; Animals; Disease Models, Animal; Humans; Melarsoprol; Mice; Trypanocidal Agents; Trypanosomiasis, African | 2002 |
[Complement: a sign of infestation of sheep by Trypanosoma brucei brucei in an experimental model: its evolution following treatment].
Topics: Animals; Arsenicals; Complement System Proteins; Disease Models, Animal; Melarsoprol; Sheep; Trypanosoma brucei brucei; Trypanosomiasis, African | 1988 |