melarsoprol and Disease Models, Animal

Topics: Animals; Antiprotozoal Agents; Benzofurans; Cations; Disease Models, Animal; Leishmania; Mice; Molecular Structure; Structure-Activity Relationship; Trypanosoma; Trypanosomiasis

Topics: Amidines; Animals; Antiprotozoal Agents; Cell Line; Cell Survival; Disease Models, Animal; Female; Leishmania donovani; Mice; Molecular Structure; Parasitic Sensitivity Tests; Plasmodium falciparum; Rats; Stereoisomerism; Structure-Activity Relationship; Triazoles; Trypanosoma brucei rhodesiense

Topics: Animals; Antiprotozoal Agents; Cell Survival; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Humans; Leukocytes, Mononuclear; Mice; Molecular Structure; Mutagenicity Tests; Nitroimidazoles; Oxidation-Reduction; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship; Trypanosomiasis, African

Topics: Animals; Antiprotozoal Agents; Bridged Bicyclo Compounds; Cell Line; Cell Survival; Disease Models, Animal; Female; Mice; Parasitic Sensitivity Tests; Piperazine; Piperazines; Plasmodium falciparum; Rats; Structure-Activity Relationship; Trypanosoma brucei rhodesiense

Topics: Amides; Animals; Disease Models, Animal; Humans; Imidazolines; Mice; Molecular Structure; Trypanocidal Agents; Trypanosoma; Trypanosomiasis, African

Topics: Animals; Antiparasitic Agents; Benzamides; Binding Sites; Cell Line; Cell Survival; Disease Models, Animal; DNA; Dose-Response Relationship, Drug; Female; Guanidines; Mice; Mice, Inbred Strains; Molecular Structure; Parasitic Sensitivity Tests; Plasmodium falciparum; Rats; Structure-Activity Relationship; Surface Plasmon Resonance; Trypanosoma brucei rhodesiense; Trypanosomiasis, African; Urea

Topics: Animals; Antiprotozoal Agents; Cell Line, Tumor; Disease Models, Animal; HSP90 Heat-Shock Proteins; Humans; Mice; Parasitemia; Plasmodium falciparum; Protein Binding; Rats; Triazoles; Trypanosoma brucei rhodesiense

Topics: Animals; Antimalarials; Cell Line, Tumor; Dipeptides; Disease Models, Animal; Histone Deacetylase Inhibitors; Histone Deacetylases; Humans; Hydroxamic Acids; Malaria; Mice; Parasites; Plasmodium falciparum; Protein Isoforms

Topics: Administration, Oral; Animals; Antiprotozoal Agents; Azabicyclo Compounds; Disease Models, Animal; Dose-Response Relationship, Drug; Injections, Intravenous; Male; Mice; Molecular Structure; Parasitic Sensitivity Tests; Plasmodium berghei; Plasmodium falciparum; Rats; Structure-Activity Relationship; Tissue Distribution; Trypanosoma brucei rhodesiense; Trypanosomiasis, African

Topics: Animals; Binding Sites; Cell Line; Chagas Disease; Disease Models, Animal; Leishmania donovani; Mice; Mice, Inbred BALB C; Nitroreductases; Parasitic Sensitivity Tests; Prodrugs; Protein Structure, Tertiary; Protozoan Proteins; Rats; Sterol 14-Demethylase; Structure-Activity Relationship; Triazoles; Trypanocidal Agents; Trypanosoma brucei rhodesiense; Trypanosoma cruzi

Topics: Animals; Diminazene; Disease Models, Animal; Drug Resistance; Kenya; Male; Melarsoprol; Mice; Pentamidine; Suramin; Treatment Outcome; Trypanocidal Agents; Trypanosoma brucei rhodesiense; Trypanosomiasis, African; Uganda; Virulence

Topics: Animals; Aquaglyceroporins; Biological Transport; Disease Models, Animal; Drug Resistance; Gene Knockout Techniques; Glycerol; Melarsoprol; Mice; Mice, Inbred BALB C; Trypanocidal Agents; Trypanosoma brucei gambiense; Trypanosomiasis, African

Topics: Animals; Diagnostic Imaging; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Humans; Luminescent Measurements; Melarsoprol; Mice; Parasite Load; Reproducibility of Results; Sensitivity and Specificity; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African

Topics: Adenine; Adenosine; Animals; ATP Binding Cassette Transporter, Subfamily B; Biological Transport; Blood-Brain Barrier; Brain; Cerebrospinal Fluid; Disease Models, Animal; Drug Interactions; Eflornithine; Indomethacin; Male; Melarsoprol; Mice; Mice, Inbred BALB C; Mice, Inbred Strains; Mice, Knockout; Multidrug Resistance-Associated Proteins; Nifurtimox; Pentamidine; Perfusion; Suramin; Trypanosoma brucei brucei; Trypanosomiasis, African

Topics: Anemia, Macrocytic; Animals; Blood Platelets; Cerebrospinal Fluid; Chlorocebus aethiops; Diminazene; Disease Models, Animal; Female; Hematology; Leukocytes; Male; Melarsoprol; Thrombocytopenia; Trypanosoma brucei rhodesiense; Trypanosomiasis, African

Topics: Administration, Oral; Africa South of the Sahara; Animals; Antiprotozoal Agents; Blood-Brain Barrier; Brain; Cyclodextrins; Disease Models, Animal; Humans; Magnetic Resonance Imaging; Male; Melarsoprol; Mice; Models, Molecular; Molecular Structure; Parasite Load; Parasitic Sensitivity Tests; Radiography; Treatment Outcome; Trypanosoma brucei brucei; Trypanosomiasis, African

Topics: Animals; Aprepitant; Disease Models, Animal; Drug Therapy, Combination; Humans; Melarsoprol; Mice; Morpholines; Neurokinin-1 Receptor Antagonists; Treatment Outcome; Trypanocidal Agents; Trypanosomiasis, African

Topics: Animals; Brain; Disease Models, Animal; Ethidium; Female; Humans; Melarsoprol; Mice; Myocardium; Time Factors; Trypanosoma brucei brucei; Trypanosomiasis, African

Topics: Adult; Animals; Area Under Curve; Arsenic; Arsenicals; Biological Assay; Chromatography, High Pressure Liquid; Disease Models, Animal; Drug Interactions; Female; Humans; Male; Melarsoprol; Mice; Mice, Inbred Strains; Microsomes, Liver; Spectrophotometry, Atomic; Trypanocidal Agents; Trypanosoma brucei gambiense; Trypanosomiasis, African

Topics: Africa South of the Sahara; Animals; Disease Models, Animal; Humans; Melarsoprol; Mice; Trypanocidal Agents; Trypanosomiasis, African

Topics: Animals; Arsenicals; Complement System Proteins; Disease Models, Animal; Melarsoprol; Sheep; Trypanosoma brucei brucei; Trypanosomiasis, African