Page last updated: 2024-08-21

melarsoprol and Brain Diseases

melarsoprol has been researched along with Brain Diseases in 14 studies

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19906 (42.86)18.7374
1990's4 (28.57)18.2507
2000's3 (21.43)29.6817
2010's1 (7.14)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Allan, M; Blum, J; Burri, C; Edielu, A; Haary, EP; Kakembo, A; Kibona, S; Kuepfer, I; Schmid, C1
Bisser, S; Būscher, P; Lejon, V; Miaka Mia Bilenge, C; N'Siesi, FX; Preux, PM; Van Nieuwenhove, S1
Checkley, AM; Gibson, WC; Jäger, HR; Mabey, DC; Pepin, J; Taylor, MN1
Hochmann, A; Lambert, PH; Poltera, AA1
Ancelle, T; Barret, B; Flachet, L; Moren, A1
Chauvière, G; Jennings, FW; Murray, M; Viode, C1
Bouteille, B; Dumas, M1
Blum, J; Brun, R; Burri, C; Merolle, A; Nkunku, S; Smith, T1
Golden, MH1
Kernbaum, S; Pialoux, G; Vachon, F1
Arroz, JO1
Champalimaud, JL; Medina, EA; Ventura, FA1
Agbowu, J; Ajayi, N; Weir, AB1
Adams, H; Dago, A; Haller, L; Merouze, F1

Trials

3 trial(s) available for melarsoprol and Brain Diseases

ArticleYear
Safety and efficacy of the 10-day melarsoprol schedule for the treatment of second stage Rhodesiense sleeping sickness.
    PLoS neglected tropical diseases, 2012, Volume: 6, Issue:8

    Topics: Adolescent; Adult; Aged; Brain Diseases; Child; Drug Administration Schedule; Endemic Diseases; Female; Humans; Male; Melarsoprol; Middle Aged; Suramin; Tanzania; Trypanocidal Agents; Trypanosoma brucei rhodesiense; Trypanosomiasis, African; Uganda

2012
Equivalence trial of melarsoprol and nifurtimox monotherapy and combination therapy for the treatment of second-stage Trypanosoma brucei gambiense sleeping sickness.
    The Journal of infectious diseases, 2007, Feb-01, Volume: 195, Issue:3

    Topics: Administration, Oral; Adult; Animals; Brain Diseases; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Injections, Intravenous; Male; Melarsoprol; Nifurtimox; Recurrence; Treatment Outcome; Trypanocidal Agents; Trypanosoma brucei gambiense; Trypanosomiasis, African

2007
Efficacy of new, concise schedule for melarsoprol in treatment of sleeping sickness caused by Trypanosoma brucei gambiense: a randomised trial.
    Lancet (London, England), 2000, Apr-22, Volume: 355, Issue:9213

    Topics: Adult; Angola; Animals; Brain Diseases; Drug Administration Schedule; Female; Humans; Injections, Intramuscular; Length of Stay; Male; Melarsoprol; Middle Aged; Severity of Illness Index; Time Factors; Treatment Outcome; Trypanocidal Agents; Trypanosoma brucei gambiense; Trypanosomiasis, African

2000

Other Studies

11 other study(ies) available for melarsoprol and Brain Diseases

ArticleYear
Human African trypanosomiasis: diagnosis, relapse and survival after severe melarsoprol-induced encephalopathy.
    Transactions of the Royal Society of Tropical Medicine and Hygiene, 2007, Volume: 101, Issue:5

    Topics: Adult; Animals; Brain Diseases; Humans; Magnetic Resonance Imaging; Male; Melarsoprol; Polymerase Chain Reaction; Recurrence; Trypanocidal Agents; Trypanosoma brucei rhodesiense; Trypanosomiasis, African

2007
Trypanosoma brucei brucei: the response to Melarsoprol in mice with cerebral trypanosomiasis. An immunopathological study.
    Clinical and experimental immunology, 1981, Volume: 46, Issue:2

    Topics: Animals; Antigen-Antibody Complex; Arsenicals; Brain; Brain Diseases; Chloroquine; Fluorescent Antibody Technique; Injections, Intraperitoneal; Injections, Intravenous; Melarsoprol; Mice; Nitroimidazoles; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African

1981
[2 epidemics of arsenical encephalopathy in the treatment of trypanosomiasis, Uganda, 1992-1993].
    Bulletin de la Societe de pathologie exotique (1990), 1994, Volume: 87, Issue:5

    Topics: Adolescent; Adult; Brain Diseases; Child; Disease Outbreaks; Drug Administration Schedule; Drug Interactions; Female; Health Status; Humans; Incidence; Male; Melarsoprol; Middle Aged; Retrospective Studies; Risk Factors; Seasons; Strongyloidiasis; Thiabendazole; Trypanocidal Agents; Trypanosomiasis, African; Uganda

1994
Topical chemotherapy for experimental African trypanosomiasis with cerebral involvement: the use of melarsoprol combined with the 5-nitroimidazole, megazol.
    Tropical medicine & international health : TM & IH, 1996, Volume: 1, Issue:3

    Topics: Administration, Topical; Animals; Brain Diseases; Dimethyl Sulfoxide; Drug Therapy, Combination; Female; Gels; Melarsoprol; Mice; Mice, Inbred Strains; Propylene Glycol; Propylene Glycols; Thiadiazoles; Trypanocidal Agents; Trypanosomiasis, African

1996
[Current status of trypanosomiasis].
    Medecine tropicale : revue du Corps de sante colonial, 1997, Volume: 57, Issue:3 Suppl

    Topics: Africa; Animals; Autoantibodies; Blood-Brain Barrier; Brain Diseases; Follow-Up Studies; Forecasting; Humans; Incidence; Melarsoprol; Nitroimidazoles; Pentamidine; Population Surveillance; Protozoan Vaccines; Recurrence; Social Problems; Socioeconomic Factors; Survival Rate; Trypanocidal Agents; Trypanosoma; Trypanosomiasis, African

1997
Arsenic, selenium, and African trypanosomiasis.
    Lancet (London, England), 1992, Jun-06, Volume: 339, Issue:8806

    Topics: Brain Diseases; Humans; Melarsoprol; Selenium; Trypanosomiasis, African

1992
[Arsenical-induced encephalopathy during the treatment of African trypanosomiasis. Apropos of a case with a favorable outcome].
    Bulletin de la Societe de pathologie exotique et de ses filiales, 1988, Volume: 81, Issue:3 Pt 2

    Topics: Adult; Animals; Arsenicals; Brain Diseases; Humans; Male; Melarsoprol; Trypanosoma brucei gambiense; Trypanosomiasis, African

1988
Melarsoprol and reactive encephalopathy in Trypanosoma brucei rhodesiense.
    Transactions of the Royal Society of Tropical Medicine and Hygiene, 1987, Volume: 81, Issue:2

    Topics: Arsenicals; Brain Diseases; Humans; Melarsoprol; Trypanosoma brucei brucei; Trypanosomiasis, African

1987
Computer-assisted tomographic findings in a patient with African trypanosomiasis.
    The Journal of tropical medicine and hygiene, 1986, Volume: 89, Issue:2

    Topics: Brain Diseases; Child, Preschool; Diminazene; Humans; Male; Melarsoprol; Meningoencephalitis; Recurrence; Tomography, X-Ray Computed; Trypanosomiasis, African

1986
Hyperendemic West African trypanosomiasis in a rural hospital setting.
    The Journal of tropical medicine and hygiene, 1985, Volume: 88, Issue:5

    Topics: Brain Diseases; Dexamethasone; Drug Administration Schedule; Drug Therapy, Combination; Hospitals, Rural; Humans; Melarsoprol; Nigeria; Suramin; Trypanosomiasis, African

1985
Clinical and pathological aspects of human African trypanosomiasis (T. b. gambiense) with particular reference to reactive arsenical encephalopathy.
    The American journal of tropical medicine and hygiene, 1986, Volume: 35, Issue:1

    Topics: Animals; Arsenicals; Brain Diseases; Humans; Melarsoprol; Seizures; Trypanosoma brucei gambiense; Trypanosomiasis, African

1986