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melarsoprol and American Trypanosomiasis

melarsoprol has been researched along with American Trypanosomiasis in 14 studies

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19903 (21.43)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's10 (71.43)24.3611
2020's1 (7.14)2.80

Authors

AuthorsStudies
Bloomer, WD; Brun, R; Kaiser, M; McKenzie, C; Papadopoulou, MV; Prasittichai, C; Torreele, E; Trunz, BB; Wilkinson, SR1
Clayton, C; De Muylder, G; Gerwick, L; Helbig, C; Knudsen, GM; Linington, RG; Mackey, ZB; Mascuch, SM; McKerrow, JH; Sanchez, LM1
Arafa, RK; Boykin, DW; Brun, R; Ismail, MA; Jones, SK; Pandharkar, T; Patrick, DA; Tidwell, RR; Wenzler, T; Werbovetz, KA; Zhu, X1
Bloomer, WD; Kaiser, M; Papadopoulou, MV; Rosenzweig, HS; Wilkinson, SR1
Aguilera-Venegas, B; Bloomer, WD; Chatelain, E; Ioset, JR; Kaiser, M; Lepesheva, GI; Papadopoulou, MV; Rosenzweig, HS; Wilkinson, SR1
Bloomer, WD; Chatelain, E; Ioset, JR; Kaiser, M; O'Shea, IP; Papadopoulou, MV; Rosenzweig, HS; Wilkinson, SR1
Bloomer, WD; Kaiser, M; O'Shea, IP; Papadopoulou, MV; Rosenzweig, HS; Wilkinson, SR1
Bloomer, WD; Kaiser, M; Papadopoulou, MV; Rosenzweig, HS; Szular, J; Wilkinson, SR1
Arroo, RRJ; Beresford, KJM; Bhambra, AS; Burrell-Saward, H; Ruparelia, KC; Tan, HL; Tasdemir, D; Yardley, V1
Brun, R; Calvet, CM; Costi, R; De Leo, A; De Vita, D; Di Santo, R; Jennings, GK; Kaiser, M; Madia, VN; Mäser, P; Messore, A; Pescatori, L; Podust, LM; Saccoliti, F; Scipione, L; Tudino, V1
Buckner, FS; Cal, M; Davis, PH; Kaiser, M; Lepesheva, GI; Sanford, AG; Vennerstrom, JL; Wallick, AI; Wang, X1
Jennings, FW1
Gutteridge, WE1

Reviews

1 review(s) available for melarsoprol and American Trypanosomiasis

ArticleYear
Existing chemotherapy and its limitations.
    British medical bulletin, 1985, Volume: 41, Issue:2

    Topics: Chagas Disease; Gentian Violet; Humans; Melarsoprol; Nifurtimox; Nitroimidazoles; Pentamidine; Suramin; Trypanocidal Agents; Trypanosomiasis, African

1985

Other Studies

13 other study(ies) available for melarsoprol and American Trypanosomiasis

ArticleYear
Novel 3-nitro-1H-1,2,4-triazole-based aliphatic and aromatic amines as anti-chagasic agents.
    Journal of medicinal chemistry, 2011, Dec-08, Volume: 54, Issue:23

    Topics: Amines; Animals; Cells, Cultured; Chagas Disease; Leishmania donovani; Mice; Nitro Compounds; Parasitic Sensitivity Tests; Rats; Structure-Activity Relationship; Triazoles; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosoma brucei rhodesiense; Trypanosoma cruzi

2011
Examination of the mode of action of the almiramide family of natural products against the kinetoplastid parasite Trypanosoma brucei.
    Journal of natural products, 2013, Apr-26, Volume: 76, Issue:4

    Topics: Animals; Biological Products; Chagas Disease; Glycolysis; Humans; Leishmania donovani; Lipopeptides; Microbodies; Microscopy, Fluorescence; Trypanosoma brucei brucei; Zebrafish

2013
Synthesis and antiprotozoal activity of dicationic m-terphenyl and 1,3-dipyridylbenzene derivatives.
    Journal of medicinal chemistry, 2013, Jul-11, Volume: 56, Issue:13

    Topics: Animals; Antiprotozoal Agents; Benzene; Chagas Disease; Female; Leishmania donovani; Mice; Mice, Inbred Strains; Models, Chemical; Molecular Structure; Parasitic Sensitivity Tests; Plasmodium falciparum; Pyridines; Structure-Activity Relationship; Terphenyl Compounds; Trypanosoma cruzi

2013
Novel nitro(triazole/imidazole)-based heteroarylamides/sulfonamides as potential antitrypanosomal agents.
    European journal of medicinal chemistry, 2014, Nov-24, Volume: 87

    Topics: Amides; Apoptosis; Blood Platelets; Cells, Cultured; Chagas Disease; Flow Cytometry; Heterocyclic Compounds; Humans; Imidazoles; In Vitro Techniques; Leishmania donovani; Leishmaniasis, Visceral; Molecular Structure; Monocytes; Platelet Activation; Sulfonamides; Triazoles; Trypanocidal Agents; Trypanosoma cruzi

2014
Novel 3-nitrotriazole-based amides and carbinols as bifunctional antichagasic agents.
    Journal of medicinal chemistry, 2015, Feb-12, Volume: 58, Issue:3

    Topics: Amides; Animals; Cell Line; Chagas Disease; Dose-Response Relationship, Drug; Methanol; Mice; Mice, Inbred BALB C; Molecular Structure; Parasitic Sensitivity Tests; Rats; Structure-Activity Relationship; Triazoles; Trypanocidal Agents; Trypanosoma brucei rhodesiense; Trypanosoma cruzi

2015
Discovery of potent nitrotriazole-based antitrypanosomal agents: In vitro and in vivo evaluation.
    Bioorganic & medicinal chemistry, 2015, Oct-01, Volume: 23, Issue:19

    Topics: Animals; Binding Sites; Cell Line; Chagas Disease; Disease Models, Animal; Leishmania donovani; Mice; Mice, Inbred BALB C; Nitroreductases; Parasitic Sensitivity Tests; Prodrugs; Protein Structure, Tertiary; Protozoan Proteins; Rats; Sterol 14-Demethylase; Structure-Activity Relationship; Triazoles; Trypanocidal Agents; Trypanosoma brucei rhodesiense; Trypanosoma cruzi

2015
3-Nitrotriazole-based piperazides as potent antitrypanosomal agents.
    European journal of medicinal chemistry, 2015, Oct-20, Volume: 103

    Topics: Animals; Cell Line; Chagas Disease; Dose-Response Relationship, Drug; Humans; Leishmania donovani; Mice; Mice, Inbred BALB C; Molecular Structure; Parasitic Sensitivity Tests; Piperazines; Rats; Structure-Activity Relationship; Triazoles; Trypanocidal Agents; Trypanosoma brucei rhodesiense; Trypanosoma cruzi

2015
Antitrypanosomal activity of 5-nitro-2-aminothiazole-based compounds.
    European journal of medicinal chemistry, 2016, Jul-19, Volume: 117

    Topics: Amides; Antiprotozoal Agents; Cell Line; Chagas Disease; Humans; Leishmania; Parasitic Sensitivity Tests; Structure-Activity Relationship; Thiazoles; Trypanocidal Agents; Trypanosoma

2016
Synthesis and antitrypanosomal activities of novel pyridylchalcones.
    European journal of medicinal chemistry, 2017, Mar-10, Volume: 128

    Topics: Animals; Cells, Cultured; Chagas Disease; Chalcones; Humans; Leishmania donovani; Leishmaniasis, Visceral; Models, Molecular; Molecular Structure; Parasitic Sensitivity Tests; Propane; Pyridines; Structure-Activity Relationship; Trypanocidal Agents; Trypanosoma cruzi

2017
Biological evaluation and structure-activity relationships of imidazole-based compounds as antiprotozoal agents.
    European journal of medicinal chemistry, 2018, Aug-05, Volume: 156

    Topics: Animals; Antiprotozoal Agents; Cell Line; Chagas Disease; Female; Humans; Imidazoles; Inhibitory Concentration 50; Leishmania donovani; Leishmaniasis, Visceral; Malaria, Falciparum; Mice; Mice, Inbred BALB C; Parasitic Sensitivity Tests; Plasmodium falciparum; Rats; Structure-Activity Relationship; Trypanosoma brucei rhodesiense; Trypanosoma cruzi; Trypanosomiasis, African

2018
A new chemotype with promise against Trypanosoma cruzi.
    Bioorganic & medicinal chemistry letters, 2020, 01-01, Volume: 30, Issue:1

    Topics: Animals; Chagas Disease; Humans; Structure-Activity Relationship; Trypanocidal Agents; Trypanosoma cruzi

2020
New leads for trypanosomiasis chemotherapy.
    Lancet (London, England), 1978, Dec-02, Volume: 2, Issue:8101

    Topics: Chagas Disease; Drug Therapy, Combination; Heme; Humans; Melarsoprol; Naphthoquinones; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosoma cruzi; Trypanosomiasis, African

1978
Chemotherapy of trypanosomiasis: the potentiation of melarsoprol by concurrent difluoromethylornithine (DFMO) treatment.
    Transactions of the Royal Society of Tropical Medicine and Hygiene, 1988, Volume: 82, Issue:4

    Topics: Animals; Arsenicals; Chagas Disease; Drug Synergism; Drug Therapy, Combination; Eflornithine; Melarsoprol; Mice; Trypanosoma brucei brucei

1988