Page last updated: 2024-08-23

melarsen oxide and African Sleeping Sickness

melarsen oxide has been researched along with African Sleeping Sickness in 11 studies

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19903 (27.27)18.7374
1990's4 (36.36)18.2507
2000's4 (36.36)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
WEINMAN, D1
APTED, FI1
BAKER, JR1
Alibu, VP; Brun, R; Clayton, C; Marti, G; Renggli, CK; Richter, C; Seebeck, T; Shahi, S; Voncken, F1
Atouguia, JM; Jennings, FW; Murray, M1
Kaminsky, R; Kralli, A; Mäser, P; Sütterlin, C1
Ariyanayagam, MR; Clayton, C; Fairlamb, AH; Krauth-Siegel, RL; Krieger, S; Schwarz, W1
Burri, C; Ericsson, O; Keiser, J1
Loiseau, PM; Lubert, P; Wolf, JG1
Bacchi, CJ; Garofalo, J; Goldberg, B; Nathan, HC; Yarlett, N1
Aba, L; Camara, P; Doua, F; Hamon, JF; Seri, B1

Other Studies

11 other study(ies) available for melarsen oxide and African Sleeping Sickness

ArticleYear
The treatment of African sleeping sickness with two new trivalent arsenical preparations (melarsen oxide and 70A).
    The American journal of tropical medicine and hygiene, 1946, Volume: 26, Issue:Suppl 5

    Topics: Animals; Arsenicals; Humans; Trypanosomiasis; Trypanosomiasis, African

1946
Four years' experience of melarsen oxide/BAL in the treatment of late-stage Rhodesian sleeping sickness.
    Transactions of the Royal Society of Tropical Medicine and Hygiene, 1957, Volume: 51, Issue:1

    Topics: Animals; Arsenicals; Black People; Humans; Trypanosomiasis; Trypanosomiasis, African

1957
The curative power of 4-(2:6-diaminopyrimidin-4-ylamino) phenylarsine oxide (compound 12,065) in infections of Trypanosoma rhodesiense in laboratory animals.
    British journal of pharmacology and chemotherapy, 1958, Volume: 13, Issue:4

    Topics: Animals; Animals, Laboratory; Arsenicals; Humans; Mice; Rats; Trypanosoma brucei rhodesiense; Trypanosomiasis; Trypanosomiasis, African; Tsetse Flies

1958
The role of Trypanosoma brucei MRPA in melarsoprol susceptibility.
    Molecular and biochemical parasitology, 2006, Volume: 146, Issue:1

    Topics: Animals; Arsenicals; Blotting, Western; Cell Line; Electrophoresis, Polyacrylamide Gel; Female; Gene Expression; Humans; Melarsoprol; Membrane Transport Proteins; Mice; Multidrug Resistance-Associated Proteins; Parasitic Sensitivity Tests; Protozoan Proteins; Reverse Transcriptase Polymerase Chain Reaction; Treatment Failure; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African

2006
The importance of 2,3-dimercaptopropinol (British anti-lewisite, BAL) in the trypanocidal activity of topical melarsoprol.
    Acta tropica, 1996, Volume: 62, Issue:2

    Topics: Administration, Topical; Animals; Arsenicals; Dimercaprol; Drug Combinations; Female; Gels; Melarsoprol; Mice; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African

1996
A nucleoside transporter from Trypanosoma brucei involved in drug resistance.
    Science (New York, N.Y.), 1999, Jul-09, Volume: 285, Issue:5425

    Topics: Adenosine; Amino Acid Sequence; Animals; Arsenicals; Biological Transport; Carrier Proteins; Cloning, Molecular; Drug Resistance; Genes, Protozoan; Membrane Proteins; Molecular Sequence Data; Mutation; Nucleoside Transport Proteins; Nucleosides; Purines; Saccharomyces cerevisiae; Substrate Specificity; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African

1999
Trypanosomes lacking trypanothione reductase are avirulent and show increased sensitivity to oxidative stress.
    Molecular microbiology, 2000, Volume: 35, Issue:3

    Topics: Animals; Anti-Bacterial Agents; Antiprotozoal Agents; Arsenicals; Cell Cycle; Cell Division; Doxycycline; Enzyme Inhibitors; Mice; Mice, Inbred BALB C; Mutation; NADH, NADPH Oxidoreductases; Oxidative Stress; Promoter Regions, Genetic; Sulfhydryl Compounds; Tetracycline; Trypanosoma brucei brucei; Trypanosomiasis, African; Virulence

2000
Investigations of the metabolites of the trypanocidal drug melarsoprol.
    Clinical pharmacology and therapeutics, 2000, Volume: 67, Issue:5

    Topics: Adult; Animals; Area Under Curve; Arsenic; Arsenicals; Biological Assay; Chromatography, High Pressure Liquid; Disease Models, Animal; Drug Interactions; Female; Humans; Male; Melarsoprol; Mice; Mice, Inbred Strains; Microsomes, Liver; Spectrophotometry, Atomic; Trypanocidal Agents; Trypanosoma brucei gambiense; Trypanosomiasis, African

2000
Contribution of dithiol ligands to in vitro and in vivo trypanocidal activities of dithiaarsanes and investigation of ligand exchange in an aqueous solution.
    Antimicrobial agents and chemotherapy, 2000, Volume: 44, Issue:11

    Topics: Animals; Arsenicals; Cysteamine; Dansyl Compounds; Disease Models, Animal; Female; Mice; Parasitic Sensitivity Tests; Structure-Activity Relationship; Sulfhydryl Compounds; Thioctic Acid; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African

2000
Differential sensitivity of Trypanosoma brucei rhodesiense isolates to in vitro lysis by arsenicals.
    Experimental parasitology, 1991, Volume: 72, Issue:2

    Topics: Animals; Arsenicals; Calcium; Calcium Channels; Drug Resistance; Female; Melarsoprol; Mice; Sulfhydryl Compounds; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African

1991
Effects of Mel B arsobal and alpha-difluoromethylornithine on the awakening electroencephalogram of humans with gambiense trypanosomiasis disease: preliminary report.
    Pharmacology, biochemistry, and behavior, 1990, Volume: 36, Issue:4

    Topics: Adolescent; Adult; Arsenicals; Dimercaprol; Drug Combinations; Eflornithine; Electroencephalography; Female; Humans; Male; Middle Aged; Trypanosomiasis, African

1990