melanotan-ii has been researched along with Obesity in 21 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 10 (47.62) | 29.6817 |
| 2010's | 8 (38.10) | 24.3611 |
| 2020's | 3 (14.29) | 2.80 |
| Authors | Studies |
|---|---|
| Bednarek, MA; Chen, AS; Chen, HY; Fong, TM; Goulet, MT; Guan, X; Howard, AD; MacIntyre, ED; MacNeil, DJ; MacNeil, T; Marsh, DJ; Nargund, RP; Rosenblum, CI; Shen, CP; Strack, AM; Tota, M; Van der Ploeg, LH; Weinberg, DH | 1 |
| Eliason, NL; Low, MJ; Martin, L; Sharpe, AL | 1 |
| Chhabra, KH; Jones, GL; Kiran, S; Low, MJ; Shangguan, G; Thompson, Z; Yu, H | 1 |
| Bouvier, M; Lanfray, D; René, P; Richard, D | 1 |
| Carter, CS; Cote, I; Green, SM; Morgan, D; Scarpace, PJ; Toklu, HZ; Tümer, N | 1 |
| Bak, S; Delhanty, P; Fani, L; van den Akker, EL; van Rossum, EF | 1 |
| Arenkiel, BR; Kim, ER; Lowell, BB; Sun, H; Tong, Q; Wu, Z; Xu, Y; Zhu, Y | 1 |
| Allard, C; Laque, A; Mauvais-Jarvis, F; Münzberg, H; Nohara, K | 1 |
| Baracos, VE; Chee, MJ; Colmers, WF; Doslikova, B; Luchtman, DW; Marks, DL | 1 |
| Adams, JM; Chhabra, KH; Fagel, B; Lam, DD; Low, MJ; Qi, N; Rubinstein, M | 1 |
| Li, DP; Ye, ZY | 1 |
| Adan, RA; Bergen, DJ; Brakkee, JH; Brans, MA; Cuppen, E; Garner, KM; Mul, JD; Toonen, PW; van Boxtel, R | 1 |
| Aubert, ML; Raposinho, PD; White, RB | 1 |
| Ebling, FJ; Hastings, MH; Horan, TL; Mercer, JG; Morgan, PJ; Schuhler, S | 1 |
| Li, G; Scarpace, PJ; Wilsey, JT; Zhang, Y | 1 |
| Boggiano, MM; Chandler, PC; Oswald, KD; Viana, JB; Wauford, PK | 1 |
| Adage, T; Adan, RA; Buwalda, B; de Vries, K; Kas, MJ; Kuipers, F; Nyakas, C; Scheurink, AJ; Thiele, TE; van Dijk, G; Wilkinson, CW | 1 |
| Friedman-Einat, M; Hen, G; Hruby, VJ; Shinder, D; Simchaev, V; Yosefi, S | 1 |
| Arima, H; Banno, R; Goto, M; Hayashi, M; Nagasaki, H; Oiso, Y; Ozaki, N; Sato, I; Watanabe, M | 1 |
| Ogawa, R; Reizes, O; Seeley, RJ; Shi, H; Strader, AD | 1 |
| Cettour-Rose, P; Rohner-Jeanrenaud, F | 1 |
2 review(s) available for melanotan-ii and Obesity
| Article | Year |
|---|---|
The role of melanocortins in body weight regulation: opportunities for the treatment of obesity.
Topics: Animals; Anti-Obesity Agents; Body Weight; Gene Expression; Humans; Melanocyte-Stimulating Hormones; Obesity; Receptors, Corticotropin; Receptors, Melanocortin | 2002 |
The melanocortin-4 receptor as target for obesity treatment: a systematic review of emerging pharmacological therapeutic options.
Topics: Acetamides; alpha-MSH; Animals; Anti-Obesity Agents; Appetite Regulation; Body Mass Index; Energy Intake; Energy Metabolism; Gene Frequency; Genotype; Humans; Obesity; Peptides, Cyclic; Phenotype; Pyrrolidines; Receptor, Melanocortin, Type 4; Receptors, Cell Surface; Spiro Compounds | 2014 |
19 other study(ies) available for melanotan-ii and Obesity
| Article | Year |
|---|---|
Melanocortin receptor agonist melanotan-II microinjected in the nucleus accumbens decreases appetitive and consumptive responding for food.
Topics: alpha-MSH; Animals; Male; Melanocortins; Mice; Mice, Inbred C57BL; Nucleus Accumbens; Obesity; Peptides, Cyclic; Pro-Opiomelanocortin; Receptor, Melanocortin, Type 4 | 2022 |
Hypothalamic POMC deficiency increases circulating adiponectin despite obesity.
Topics: Adiponectin; Adipose Tissue; alpha-MSH; Animals; Arcuate Nucleus of Hypothalamus; Caloric Restriction; Disease Models, Animal; Female; Melanocortins; Metabolism, Inborn Errors; Mice; Mice, Knockout; Neurons; Obesity; Peptides, Cyclic; Pro-Opiomelanocortin; Signal Transduction; Sympathetic Nervous System | 2020 |
Pharmacological chaperone action in humanized mouse models of MC4R-linked obesity.
Topics: alpha-MSH; Animals; Blood Glucose; Body Weight; Carrier Proteins; Cell Membrane; Disease Models, Animal; Female; HEK293 Cells; Humans; Male; Mice; Mutation; Obesity; Peptides, Cyclic; Phenotype; Protein Conformation; Receptor, Melanocortin, Type 4 | 2021 |
Limiting feeding to the active phase reduces blood pressure without the necessity of caloric reduction or fat mass loss.
Topics: Activity Cycles; Adiposity; alpha-MSH; Animals; Arterial Pressure; Diet, High-Fat; Disease Models, Animal; Energy Intake; Energy Metabolism; Fasting; Feeding Behavior; Hypertension; Male; Obesity; Peptides, Cyclic; Photoperiod; Rats, Inbred BN; Rats, Inbred F344; Time Factors | 2018 |
Glutamate mediates the function of melanocortin receptor 4 on Sim1 neurons in body weight regulation.
Topics: alpha-MSH; Animals; Basic Helix-Loop-Helix Transcription Factors; Body Weight; Energy Metabolism; Female; Glutamic Acid; Hyperphagia; Male; Mice; Mice, Knockout; Neurons; Obesity; Paraventricular Hypothalamic Nucleus; Peptides, Cyclic; Potassium Chloride; Receptor, Melanocortin, Type 4; Repressor Proteins; RNA, Messenger; Vesicular Glutamate Transport Protein 2 | 2013 |
Central mechanisms of adiposity in adult female mice with androgen excess.
Topics: Adipose Tissue, Brown; Adiposity; alpha-MSH; Androgens; Animals; Arcuate Nucleus of Hypothalamus; Body Composition; Body Weight; Dihydrotestosterone; Energy Metabolism; Female; Hyperphagia; Hypothalamus; Intra-Abdominal Fat; Ion Channels; Leptin; Mice; Mice, Inbred C57BL; Mitochondrial Proteins; Obesity; Peptides, Cyclic; Pro-Opiomelanocortin; Receptor, Melanocortin, Type 4; RNA, Messenger; Uncoupling Protein 1; Up-Regulation | 2014 |
Defense of Elevated Body Weight Setpoint in Diet-Induced Obese Rats on Low Energy Diet Is Mediated by Loss of Melanocortin Sensitivity in the Paraventricular Hypothalamic Nucleus.
Topics: alpha-MSH; Animals; Arcuate Nucleus of Hypothalamus; Body Weight; Caloric Restriction; Diet; Dietary Fats; gamma-Aminobutyric Acid; Leptin; Melanocortins; Neuropeptide Y; Obesity; Paraventricular Hypothalamic Nucleus; Peptides, Cyclic; Rats; Rats, Sprague-Dawley; Receptor, Melanocortin, Type 4; Ventromedial Hypothalamic Nucleus | 2015 |
Hypothalamic POMC Deficiency Improves Glucose Tolerance Despite Insulin Resistance by Increasing Glycosuria.
Topics: Agouti-Related Protein; alpha-MSH; Animals; Arcuate Nucleus of Hypothalamus; Blood Glucose; Blotting, Western; Epinephrine; Glucose Tolerance Test; Glucose Transporter Type 2; Glycosuria, Renal; Hypothalamus; Injections, Intraventricular; Insulin Resistance; Kidney; Mice; Mice, Knockout; Norepinephrine; Obesity; Peptides, Cyclic; Pro-Opiomelanocortin; Receptors, Melanocortin; Sympathetic Nervous System | 2016 |
Activation of the melanocortin-4 receptor causes enhanced excitation in presympathetic paraventricular neurons in obese Zucker rats.
Topics: alpha-MSH; Animals; Bicuculline; Guanosine Diphosphate; Kynurenic Acid; Male; Melanocyte-Stimulating Hormones; Neurons; Obesity; Paraventricular Hypothalamic Nucleus; Patch-Clamp Techniques; Peptides, Cyclic; Rats; Rats, Zucker; Receptor, Melanocortin, Type 4; Thionucleotides | 2011 |
Melanocortin receptor 4 deficiency affects body weight regulation, grooming behavior, and substrate preference in the rat.
Topics: alpha-MSH; Animals; Animals, Genetically Modified; Disease Models, Animal; Eating; Energy Metabolism; Food Preferences; Grooming; Obesity; Peptides, Cyclic; Rats; Receptor, Melanocortin, Type 4; Weight Gain | 2012 |
The melanocortin agonist Melanotan-II reduces the orexigenic and adipogenic effects of neuropeptide Y (NPY) but does not affect the NPY-driven suppressive effects on the gonadotropic and somatotropic axes in the male rat.
Topics: Adipocytes; Adipose Tissue; alpha-MSH; Animals; Carrier Proteins; Drinking; Drug Interactions; Eating; Gene Expression; Gonadal Steroid Hormones; Growth Hormone-Releasing Hormone; Hypothalamus; Insulin; Insulin-Like Growth Factor I; Intracellular Signaling Peptides and Proteins; Leptin; Male; Neuropeptide Y; Neuropeptides; Obesity; Orexins; Peptides, Cyclic; Pro-Opiomelanocortin; Rats; Rats, Sprague-Dawley; Weight Gain | 2003 |
Feeding and behavioural effects of central administration of the melanocortin 3/4-R antagonist SHU9119 in obese and lean Siberian hamsters.
Topics: alpha-MSH; Analysis of Variance; Animals; Body Weight; Cricetinae; Dose-Response Relationship, Drug; Drug Interactions; Eating; Feeding Behavior; Grooming; Injections, Intraventricular; Male; Melanocyte-Stimulating Hormones; Motor Activity; Obesity; Peptides, Cyclic; Photoperiod; Receptors, Corticotropin; Time Factors | 2004 |
Unabated anorexic and enhanced thermogenic responses to melanotan II in diet-induced obese rats despite reduced melanocortin 3 and 4 receptor expression.
Topics: Acetyl-CoA Carboxylase; Adipose Tissue, Brown; alpha-MSH; Animals; Body Temperature Regulation; Carnitine O-Palmitoyltransferase; Cholesterol; Diet; Energy Intake; Female; Hypothalamus; Insulin; Models, Animal; Muscle, Skeletal; Obesity; Oxygen Consumption; Peptides, Cyclic; Rats; Rats, Sprague-Dawley; Receptor, Melanocortin, Type 3; Receptor, Melanocortin, Type 4 | 2004 |
Feeding response to melanocortin agonist predicts preference for and obesity from a high-fat diet.
Topics: alpha-MSH; Analysis of Variance; Animals; Behavior, Animal; Body Weight; Dietary Fats; Eating; Feeding Behavior; Injections, Intraventricular; Male; Obesity; Oxygen Consumption; Peptides, Cyclic; Rats; Rats, Sprague-Dawley; Time Factors | 2005 |
Reduced anorexigenic efficacy of leptin, but not of the melanocortin receptor agonist melanotan-II, predicts diet-induced obesity in rats.
Topics: alpha-MSH; Animals; Anorexia; Diet; Eating; Humans; Injections, Intraventricular; Leptin; Male; Neurons; Neurosecretory Systems; Obesity; Paraventricular Hypothalamic Nucleus; Peptides, Cyclic; Predictive Value of Tests; Rats; Rats, Wistar; Receptors, Leptin; Receptors, Melanocortin | 2005 |
The melanocortin circuit in obese and lean strains of chicks.
Topics: alpha-MSH; Animals; Chickens; Female; Gene Expression; Hypothalamus; Obesity; Peptides, Cyclic; Phenotype; Pro-Opiomelanocortin; Receptor, Melanocortin, Type 4; Reverse Transcriptase Polymerase Chain Reaction; Species Specificity | 2006 |
Central administration of melanocortin agonist increased insulin sensitivity in diet-induced obese rats.
Topics: Adipocytes; Adipose Tissue, White; alpha-MSH; Animals; Body Weight; Cytokines; Diet; Eating; Insulin; Insulin Resistance; Male; Melanocortins; Obesity; Peptides, Cyclic; Rats; Rats, Sprague-Dawley | 2007 |
The effects of the melanocortin agonist (MT-II) on subcutaneous and visceral adipose tissue in rodents.
Topics: alpha-MSH; Animals; Body Weight; Intra-Abdominal Fat; Melanocortins; Mice; Mice, Obese; Obesity; Peptides, Cyclic; Subcutaneous Fat | 2007 |
The leptin-like effects of 3-d peripheral administration of a melanocortin agonist are more marked in genetically obese Zucker (fa/fa) than in lean rats.
Topics: Adipose Tissue; alpha-MSH; Animals; Blood Glucose; Blotting, Northern; Body Weight; Carnitine O-Palmitoyltransferase; Eating; Fatty Acids, Nonesterified; Injections, Intraperitoneal; Insulin; Leptin; Lipid Metabolism; Liver; Male; Melanocyte-Stimulating Hormones; Muscle, Skeletal; Obesity; Peptides, Cyclic; Rats; Rats, Zucker; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2002 |