Page last updated: 2024-08-26

melanotan-ii and Body Weight

melanotan-ii has been researched along with Body Weight in 27 studies

*Body Weight: The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms. [MeSH]

Research

Studies (27)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	16 (59.26)	29.6817
2010's	9 (33.33)	24.3611
2020's	2 (7.41)	2.80

Authors

Authors	Studies
Bednarek, MA; Chen, AS; Chen, HY; Fong, TM; Goulet, MT; Guan, X; Howard, AD; MacIntyre, ED; MacNeil, DJ; MacNeil, T; Marsh, DJ; Nargund, RP; Rosenblum, CI; Shen, CP; Strack, AM; Tota, M; Van der Ploeg, LH; Weinberg, DH	1
Amemiya, N; Arima, T; Fujima, S; Furuichi, T; Sano, Y	1
Bouvier, M; Lanfray, D; René, P; Richard, D	1
Carter, CS; Côté, I; Green, SM; Morgan, D; Scarpace, PJ; Tümer, N	1
Rahmouni, K; Shibamoto, T; Tanida, M; Yamamoto, N	1
Arenkiel, BR; Kim, ER; Lowell, BB; Sun, H; Tong, Q; Wu, Z; Xu, Y; Zhu, Y	1
Allard, C; Laque, A; Mauvais-Jarvis, F; Münzberg, H; Nohara, K	1
Baracos, VE; Chee, MJ; Colmers, WF; Doslikova, B; Luchtman, DW; Marks, DL	1
Carter, CS; Côté, I; Kirichenko, N; Morgan, D; Sakarya, Y; Scarpace, PJ; Tümer, N	1
Collazo, R; Gao, Y; Li, G; Scarpace, PJ; Zhang, Y	1
Bassi, M; da Silva, AA; do Carmo, JM; Hall, JE	1
Blevins, JE; Ho, JM; Kaiyala, KJ; Matsumoto, K; Moralejo, DH; Thatcher, BS; Wolden-Hanson, TH	1
Ebling, FJ; Hastings, MH; Horan, TL; Mercer, JG; Morgan, PJ; Schuhler, S	2
Buntin, JD; Schiöth, HB; Strader, AD	1
Grippo, JF; Rumennik, L; Samama, P	1
Baile, CA; Choi, YH; Della-Fera, MA; Hartzell, DL; Li, C; Lin, J	1
Matheny, M; Scarpace, PJ; Tümer, N; Zhang, Y; Zolotukhin, S	1
Baile, CA; Choi, YH; Della-Fera, MA; Hartzell, DL; Li, C; Lin, J; Page, K; Westby, A	1
Arima, H; Banno, R; Goto, M; Hayashi, M; Murase, T; Oiso, Y; Sato, I; Sugimura, Y	1
Boggiano, MM; Chandler, PC; Oswald, KD; Viana, JB; Wauford, PK	1
Arima, H; Banno, R; Goto, M; Hayashi, M; Nagasaki, H; Oiso, Y; Ozaki, N; Sato, I; Watanabe, M	1
Ogawa, R; Reizes, O; Seeley, RJ; Shi, H; Strader, AD	1
Low, MJ; Tolle, V	1
Baumane, L; Dambrova, M; Kalvinsh, I; Liepinsh, E; Muceniece, R; Vilskersts, R; Wikberg, JE; Zvejniece, L	1
Camacho, RE; Chen, AS; Chen, HY; Fisher, J; Forrest, MJ; Frazier, EG; Gopal-Truter, S; Guan, XM; MacIntyre, DE; Marsh, DJ; Mellin, TN; Metzger, JM; Strack, AM; Trumbauer, ME; Van der Ploeg, LH; Yu, H	1
Cettour-Rose, P; Rohner-Jeanrenaud, F	1

Reviews

1 review(s) available for melanotan-ii and Body Weight

Article	Year
The role of melanocortins in body weight regulation: opportunities for the treatment of obesity. European journal of pharmacology, 2002, Apr-12, Volume: 440, Issue:2-3 Topics: Animals; Anti-Obesity Agents; Body Weight; Gene Expression; Humans; Melanocyte-Stimulating Hormones; Obesity; Receptors, Corticotropin; Receptors, Melanocortin	2002

Other Studies

26 other study(ies) available for melanotan-ii and Body Weight

Article	Year
CAPS2 deficiency induces proopiomelanocortin accumulation in pituitary and affects food intake behavior in mice. Neuroscience letters, 2020, 11-01, Volume: 738 Topics: alpha-MSH; Animals; Body Weight; Calcium-Binding Proteins; Eating; Hypothalamus; Male; Mice; Mice, Knockout; Nerve Tissue Proteins; Neurons; Peptides, Cyclic; Pituitary Gland; Pro-Opiomelanocortin	2020
Pharmacological chaperone action in humanized mouse models of MC4R-linked obesity. JCI insight, 2021, 02-22, Volume: 6, Issue:4 Topics: alpha-MSH; Animals; Blood Glucose; Body Weight; Carrier Proteins; Cell Membrane; Disease Models, Animal; Female; HEK293 Cells; Humans; Male; Mice; Mutation; Obesity; Peptides, Cyclic; Phenotype; Protein Conformation; Receptor, Melanocortin, Type 4	2021
Activation of the central melanocortin system in rats persistently reduces body and fat mass independently of caloric reduction. Canadian journal of physiology and pharmacology, 2018, Volume: 96, Issue:3 Topics: Adipose Tissue; alpha-MSH; Animals; Body Weight; Caloric Restriction; Eating; Male; Melanocortins; Peptides, Cyclic; Rats	2018
Involvement of hypothalamic AMP-activated protein kinase in leptin-induced sympathetic nerve activation. PloS one, 2013, Volume: 8, Issue:2 Topics: alpha-MSH; AMP-Activated Protein Kinases; Animals; Blood Glucose; Blotting, Western; Body Weight; Catecholamines; Eating; Fatty Acids, Nonesterified; Hemodynamics; Hypothalamus; Injections, Intraventricular; Leptin; Male; Peptides, Cyclic; Protein Subunits; Rats; Rats, Wistar; RNA Interference; Sympathetic Nervous System	2013
Glutamate mediates the function of melanocortin receptor 4 on Sim1 neurons in body weight regulation. Cell metabolism, 2013, Dec-03, Volume: 18, Issue:6 Topics: alpha-MSH; Animals; Basic Helix-Loop-Helix Transcription Factors; Body Weight; Energy Metabolism; Female; Glutamic Acid; Hyperphagia; Male; Mice; Mice, Knockout; Neurons; Obesity; Paraventricular Hypothalamic Nucleus; Peptides, Cyclic; Potassium Chloride; Receptor, Melanocortin, Type 4; Repressor Proteins; RNA, Messenger; Vesicular Glutamate Transport Protein 2	2013
Central mechanisms of adiposity in adult female mice with androgen excess. Obesity (Silver Spring, Md.), 2014, Volume: 22, Issue:6 Topics: Adipose Tissue, Brown; Adiposity; alpha-MSH; Androgens; Animals; Arcuate Nucleus of Hypothalamus; Body Composition; Body Weight; Dihydrotestosterone; Energy Metabolism; Female; Hyperphagia; Hypothalamus; Intra-Abdominal Fat; Ion Channels; Leptin; Mice; Mice, Inbred C57BL; Mitochondrial Proteins; Obesity; Peptides, Cyclic; Pro-Opiomelanocortin; Receptor, Melanocortin, Type 4; RNA, Messenger; Uncoupling Protein 1; Up-Regulation	2014
Defense of Elevated Body Weight Setpoint in Diet-Induced Obese Rats on Low Energy Diet Is Mediated by Loss of Melanocortin Sensitivity in the Paraventricular Hypothalamic Nucleus. PloS one, 2015, Volume: 10, Issue:10 Topics: alpha-MSH; Animals; Arcuate Nucleus of Hypothalamus; Body Weight; Caloric Restriction; Diet; Dietary Fats; gamma-Aminobutyric Acid; Leptin; Melanocortins; Neuropeptide Y; Obesity; Paraventricular Hypothalamic Nucleus; Peptides, Cyclic; Rats; Rats, Sprague-Dawley; Receptor, Melanocortin, Type 4; Ventromedial Hypothalamic Nucleus	2015
Activation of the central melanocortin system chronically reduces body mass without the necessity of long-term caloric restriction. Canadian journal of physiology and pharmacology, 2017, Volume: 95, Issue:2 Topics: Adiposity; alpha-MSH; Animals; Body Weight; Caloric Restriction; Dose-Response Relationship, Drug; Eating; Hand Strength; Infusions, Intraventricular; Male; Motor Activity; Peptides, Cyclic; Rats	2017
Intermittent MTII application evokes repeated anorexia and robust fat and weight loss. Peptides, 2010, Volume: 31, Issue:4 Topics: Acetyl-CoA Carboxylase; Adipose Tissue; alpha-MSH; Animals; Anorexia; Body Weight; Humans; Ion Channels; Male; Mitochondrial Proteins; Peptides, Cyclic; Rats; Rats, Inbred F344; Uncoupling Protein 1; Weight Loss	2010
Systemic but not central nervous system nitric oxide synthase inhibition exacerbates the hypertensive effects of chronic melanocortin-3/4 receptor activation. Hypertension (Dallas, Tex. : 1979), 2011, Volume: 57, Issue:3 Topics: alpha-MSH; Analysis of Variance; Animals; Blood Glucose; Body Weight; Catheters, Indwelling; Eating; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Hypertension; Insulin; Leptin; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Peptides, Cyclic; Rats; Rats, Sprague-Dawley; Receptor, Melanocortin, Type 3; Receptor, Melanocortin, Type 4; Telemetry	2011
Alterations in activity and energy expenditure contribute to lean phenotype in Fischer 344 rats lacking the cholecystokinin-1 receptor gene. American journal of physiology. Regulatory, integrative and comparative physiology, 2012, Dec-15, Volume: 303, Issue:12 Topics: alpha-MSH; Animals; Body Weight; Devazepide; Eating; Energy Metabolism; Gene Deletion; Male; Models, Animal; Motor Activity; Peptides, Cyclic; Phenotype; Rats; Rats, Inbred F344; Rats, Mutant Strains; Receptor, Cholecystokinin A; Sequence Deletion; Thinness	2012
Decrease of food intake by MC4-R agonist MTII in Siberian hamsters in long and short photoperiods. American journal of physiology. Regulatory, integrative and comparative physiology, 2003, Volume: 284, Issue:1 Topics: alpha-MSH; Animals; Body Weight; Circadian Rhythm; Cricetinae; Dose-Response Relationship, Drug; Energy Metabolism; Fasting; Feeding Behavior; Food Deprivation; Hypothalamus; Male; Peptides, Cyclic; Phodopus; Photoperiod; Receptor, Melanocortin, Type 4; Receptors, Corticotropin; Time Factors	2003
The role of the melanocortin system and the melanocortin-4 receptor in ring dove (Streptopelia risoria) feeding behavior. Brain research, 2003, Jan-17, Volume: 960, Issue:1-2 Topics: Agouti-Related Protein; alpha-MSH; Animals; Body Weight; Columbidae; Eating; Energy Metabolism; Feeding Behavior; Food Deprivation; Hypothalamus; Immunohistochemistry; Injections, Intraventricular; Intercellular Signaling Peptides and Proteins; Male; Melanocyte-Stimulating Hormones; Microinjections; Neurons; Peptides, Cyclic; Proteins; Receptor, Melanocortin, Type 4; Receptors, Corticotropin	2003
The melanocortin receptor MCR4 controls fat consumption. Regulatory peptides, 2003, May-15, Volume: 113, Issue:1-3 Topics: alpha-MSH; Animals; Body Weight; Dietary Fats; Dose-Response Relationship, Drug; Eating; Energy Intake; Feeding Behavior; Female; Food Preferences; Humans; Male; Mice; Mice, Inbred C57BL; Mutation; Peptides, Cyclic; Receptor, Melanocortin, Type 4	2003
MTII administered peripherally reduces fat without invoking apoptosis in rats. Physiology & behavior, 2003, Volume: 79, Issue:2 Topics: Adipose Tissue; alpha-MSH; Animals; Apoptosis; Body Temperature; Body Weight; Drinking; Eating; Epididymis; Fatty Acids, Nonesterified; Injections, Intraperitoneal; Male; Osmolar Concentration; Peptides, Cyclic; Rats; Rats, Sprague-Dawley; Retroperitoneal Space	2003
Leptin-induced leptin resistant rats exhibit enhanced responses to the melanocortin agonist MT II. Neuropharmacology, 2003, Volume: 45, Issue:2 Topics: alpha-MSH; Animals; Body Weight; Drug Resistance; Eating; Leptin; Male; Peptides, Cyclic; Rats; Rats, Inbred BN; Rats, Inbred F344; Receptors, Corticotropin; Receptors, Melanocortin	2003
Melanocortin receptors mediate leptin effects on feeding and body weight but not adipose apoptosis. Physiology & behavior, 2003, Volume: 79, Issue:4-5 Topics: Adipose Tissue; alpha-MSH; Animals; Apoptosis; Body Composition; Body Weight; Feeding Behavior; Injections, Intraventricular; Leptin; Male; Melanocyte-Stimulating Hormones; Peptides, Cyclic; Rats; Rats, Sprague-Dawley; Receptors, Melanocortin; Signal Transduction	2003
Feeding and behavioural effects of central administration of the melanocortin 3/4-R antagonist SHU9119 in obese and lean Siberian hamsters. Behavioural brain research, 2004, Jul-09, Volume: 152, Issue:2 Topics: alpha-MSH; Analysis of Variance; Animals; Body Weight; Cricetinae; Dose-Response Relationship, Drug; Drug Interactions; Eating; Feeding Behavior; Grooming; Injections, Intraventricular; Male; Melanocyte-Stimulating Hormones; Motor Activity; Obesity; Peptides, Cyclic; Photoperiod; Receptors, Corticotropin; Time Factors	2004
The melanocortin agonist melanotan II increases insulin sensitivity in OLETF rats. Peptides, 2004, Volume: 25, Issue:8 Topics: Adipose Tissue; alpha-MSH; Animals; Body Weight; Eating; Glucose Tolerance Test; Homeostasis; Insulin Resistance; Male; Models, Biological; Peptides, Cyclic; Rats; Rats, Inbred OLETF; Time Factors; Triglycerides	2004
Feeding response to melanocortin agonist predicts preference for and obesity from a high-fat diet. Physiology & behavior, 2005, Jun-02, Volume: 85, Issue:2 Topics: alpha-MSH; Analysis of Variance; Animals; Behavior, Animal; Body Weight; Dietary Fats; Eating; Feeding Behavior; Injections, Intraventricular; Male; Obesity; Oxygen Consumption; Peptides, Cyclic; Rats; Rats, Sprague-Dawley; Time Factors	2005
Central administration of melanocortin agonist increased insulin sensitivity in diet-induced obese rats. FEBS letters, 2007, Mar-20, Volume: 581, Issue:6 Topics: Adipocytes; Adipose Tissue, White; alpha-MSH; Animals; Body Weight; Cytokines; Diet; Eating; Insulin; Insulin Resistance; Male; Melanocortins; Obesity; Peptides, Cyclic; Rats; Rats, Sprague-Dawley	2007
The effects of the melanocortin agonist (MT-II) on subcutaneous and visceral adipose tissue in rodents. The Journal of pharmacology and experimental therapeutics, 2007, Volume: 322, Issue:3 Topics: alpha-MSH; Animals; Body Weight; Intra-Abdominal Fat; Melanocortins; Mice; Mice, Obese; Obesity; Peptides, Cyclic; Subcutaneous Fat	2007
In vivo evidence for inverse agonism of Agouti-related peptide in the central nervous system of proopiomelanocortin-deficient mice. Diabetes, 2008, Volume: 57, Issue:1 Topics: Agouti-Related Protein; alpha-MSH; Animals; Anorexia; Body Weight; Brain; DNA Primers; Energy Intake; Energy Metabolism; Female; Ghrelin; Hyperphagia; Injections, Intraventricular; Male; Mice; Mice, Knockout; Oxygen Consumption; Peptide Fragments; Peptides, Cyclic; Pro-Opiomelanocortin; Reverse Transcriptase Polymerase Chain Reaction	2008
Functional evaluation of THIQ, a melanocortin 4 receptor agonist, in models of food intake and inflammation. Basic & clinical pharmacology & toxicology, 2007, Volume: 101, Issue:6 Topics: alpha-MSH; Animals; Anti-Inflammatory Agents; Body Weight; Brain; Disease Models, Animal; Dose-Response Relationship, Drug; Eating; Electron Spin Resonance Spectroscopy; Inflammation; Injections, Intraventricular; Lipopolysaccharides; Male; Mice; Mice, Inbred ICR; Nitric Oxide; Peptides, Cyclic; Rats; Rats, Wistar; Receptor, Melanocortin, Type 4; Tetrahydroisoquinolines; Triazoles	2007
Role of the melanocortin-4 receptor in metabolic rate and food intake in mice. Transgenic research, 2000, Volume: 9, Issue:2 Topics: alpha-MSH; Animals; Basal Metabolism; Body Composition; Body Weight; Eating; In Situ Hybridization; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Motor Activity; Peptides, Cyclic; Receptor, Melanocortin, Type 4; Receptors, Peptide	2000
The leptin-like effects of 3-d peripheral administration of a melanocortin agonist are more marked in genetically obese Zucker (fa/fa) than in lean rats. Endocrinology, 2002, Volume: 143, Issue:6 Topics: Adipose Tissue; alpha-MSH; Animals; Blood Glucose; Blotting, Northern; Body Weight; Carnitine O-Palmitoyltransferase; Eating; Fatty Acids, Nonesterified; Injections, Intraperitoneal; Insulin; Leptin; Lipid Metabolism; Liver; Male; Melanocyte-Stimulating Hormones; Muscle, Skeletal; Obesity; Peptides, Cyclic; Rats; Rats, Zucker; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger	2002