Page last updated: 2024-09-05

melagatran and Venous Thrombosis

melagatran has been researched along with Venous Thrombosis in 30 studies

Research

Studies (30)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's28 (93.33)29.6817
2010's2 (6.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bergmann, JF; Lloret Linares, C1
Fujimoto, T; Hiroe, K; Imaeda, Y; Kawamura, M; Konishi, N; Kubo, K; Shofuda, K1
Eriksson, H; Eriksson, UG; Lapidus, L; Larson, G; Olsson, CG; Thuresson, A; Wåhlander, K1
Agnelli, G; Cohen, AT; Dahl, OE; Eriksson, BI; Eskilson, C; Frison, L; Mouret, P; Nylander, I; Ogren, M; Rosencher, N1
Hamaad, A; Lip, GY; Tayebjee, MH1
Eriksson, BI; Eriksson, UG; Frison, L; Gisleskog, PO; Gustafsson, D; Hamrén, B; Karlsson, MO; Mandema, JW; Wählby, U1
Börjesson, I; Carlsson, S; Elg, M1
Gustafsson, D1
Drouet, L1
Eichinger, S; Kyrle, PA; Weltermann, A1
Agnelli, G; Andersson, M; Cohen, AT; Dahl, OE; Eriksson, BI; Eskilson, C; Freij, A; Kälebo, P; Lassen, MR; Mouret, P; Panfilov, S; Rosencher, N1
Evans, HC; Faulds, D; Perry, CM1
Al-Mousa, EN; Salam, AM1
Weitz, J1
Bauersachs, R; Brehme, S; Caspary, L; Creutzig, A; Harenberg, J; Hoffmann, U; Landgraf, H; Schellong, S1
Brighton, TA1
Cimminiello, C; Planès, A; Samama, MM1
Boda, Z1
Petersen, P1
Eriksson, UG; Hellgren, M; Johansson, S; Wåhlander, K1
Carlsson, S; Elg, M1
Nielsen, JD1
Meyer Samama, M1
Brighton, TA; Ho, SJ1
Hauel, N; Priepke, H; Ries, UJ; Stassen, JM; Wienen, W1
Heinzl, S1
Arfwidsson, AC; Bylock, A; Eriksson, BI; Eriksson, UG; Fager, G; Frison, L; Gustafsson, D; Kälebo, P1
Fiessinger, JN1
Andersson, C; Bylock, A; Eriksson, BI; Frison, L; Gustafsson, D; Larson, G; Lindahl, TL; Wåhlander, K1
Ahnfelt, L; Arfwidsson, AC; Björkström, S; Elvander, CS; Eriksson, BI; Eriksson, UG; Folestad, A; Frison, L; Kälebo, P; Ogren, M; Sjöstedt, A1

Reviews

15 review(s) available for melagatran and Venous Thrombosis

ArticleYear
The METHRO trials.
    Expert opinion on investigational drugs, 2003, Volume: 12, Issue:5

    Topics: Azetidines; Benzylamines; Clinical Trials as Topic; Glycine; Humans; Orthopedic Procedures; Prodrugs; Thrombin; Venous Thrombosis

2003
Oral direct thrombin inhibitors in clinical development.
    Journal of internal medicine, 2003, Volume: 254, Issue:4

    Topics: Anticoagulants; Azetidines; Benzimidazoles; Benzylamines; Dabigatran; Glycine; Hemostasis; Humans; Prodrugs; Pyridines; Stroke; Thrombin; Thrombosis; Venous Thrombosis; Vitamin K

2003
[Treatment and prevention of venous thromboembolic events: present and future antithrombotic agents].
    Bulletin de l'Academie nationale de medecine, 2003, Volume: 187, Issue:1

    Topics: Administration, Oral; Azetidines; Benzylamines; Clinical Trials as Topic; Coronary Thrombosis; Factor Xa Inhibitors; Fibrinolytic Agents; Fondaparinux; Glycine; Hirudin Therapy; Humans; Orthopedics; Polysaccharides; Prodrugs; Prothrombin; Research; Thrombin; Thromboembolism; Time Factors; Venous Thrombosis

2003
Novel anticoagulants for the prevention and treatment of venous thromboembolism.
    Wiener medizinische Wochenschrift (1946), 2003, Volume: 153, Issue:19-20

    Topics: Anticoagulants; Azetidines; Benzylamines; Blood Coagulation Factors; Drugs, Investigational; Fondaparinux; Glycine; Heparin; Heparin, Low-Molecular-Weight; Humans; Polysaccharides; Pulmonary Embolism; Research; Thrombin; Venous Thrombosis; Vitamin K

2003
Ximelagatran/Melagatran: a review of its use in the prevention of venous thromboembolism in orthopaedic surgery.
    Drugs, 2004, Volume: 64, Issue:6

    Topics: Anticoagulants; Azetidines; Benzylamines; Drug Interactions; Drug Therapy, Combination; Enoxaparin; Glycine; Humans; Orthopedic Procedures; Randomized Controlled Trials as Topic; Thrombin; Thromboembolism; Venous Thrombosis; Warfarin

2004
The therapeutic potential of ximelagatran to become the anticoagulant of choice in medicine: a review of recently completed clinical trials.
    Expert opinion on pharmacotherapy, 2004, Volume: 5, Issue:6

    Topics: Anticoagulants; Atrial Fibrillation; Azetidines; Benzylamines; Clinical Trials as Topic; Coronary Artery Disease; Drug Therapy, Combination; Glycine; Humans; Prodrugs; Stroke; Thrombin; Thromboembolism; Venous Thrombosis

2004
Orally active direct thrombin inhibitors.
    Seminars in vascular medicine, 2003, Volume: 3, Issue:2

    Topics: Administration, Oral; Anticoagulants; Atrial Fibrillation; Azetidines; Benzylamines; Blood Coagulation; Drug Monitoring; Glycine; Humans; International Normalized Ratio; Postoperative Complications; Prodrugs; Stroke; Thrombin; Thrombosis; Venous Thrombosis; Vitamin K

2003
[Prevention and treatment of deep vein thrombosis with ximelagatran].
    Deutsche medizinische Wochenschrift (1946), 2004, Jul-23, Volume: 129, Issue:30

    Topics: Anticoagulants; Arginine; Azetidines; Benzylamines; Fondaparinux; Glycine; Heparin; Hirudin Therapy; Humans; Pipecolic Acids; Polysaccharides; Prodrugs; Sulfonamides; Thrombin; Venous Thrombosis

2004
The direct thrombin inhibitor melagatran/ximelagatran.
    The Medical journal of Australia, 2004, Oct-18, Volume: 181, Issue:8

    Topics: Anticoagulants; Azetidines; Benzylamines; Blood Coagulation; Glycine; Humans; Myocardial Infarction; Secondary Prevention; Stroke; Thrombin; Treatment Outcome; Venous Thrombosis

2004
[New anticoagulants in clinical practice].
    Orvosi hetilap, 2004, Dec-05, Volume: 145, Issue:49

    Topics: Anticoagulants; Azetidines; Benzylamines; Fondaparinux; Glycine; Humans; Polysaccharides; Protein C; Pulmonary Embolism; Recombinant Proteins; Venous Thrombosis

2004
Ximelagatran--a promising new drug in thromboembolic disorders.
    Current pharmaceutical design, 2005, Volume: 11, Issue:4

    Topics: Administration, Oral; Anticoagulants; Azetidines; Benzylamines; Glycine; Humans; Prodrugs; Randomized Controlled Trials as Topic; Stroke; Thrombin; Thromboembolism; Venous Thrombosis

2005
[Thromboprophylaxis in hip and knee arthroplasty. Are the new anticoagulants better than those previously used?].
    Ugeskrift for laeger, 2005, May-23, Volume: 167, Issue:21

    Topics: Anticoagulants; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Azetidines; Benzylamines; Clinical Trials, Phase III as Topic; Fibrinolytic Agents; Fondaparinux; Glycine; Humans; Polysaccharides; Postoperative Complications; Pulmonary Embolism; Thromboembolism; Venous Thrombosis

2005
[The new antithrombotic agents].
    Presse medicale (Paris, France : 1983), 2005, Oct-22, Volume: 34, Issue:18

    Topics: Administration, Oral; Angioplasty, Balloon, Coronary; Anticoagulants; Aspirin; Azetidines; Benzylamines; Clopidogrel; Fibrinolytic Agents; Glycine; Hirudins; Humans; Injections, Subcutaneous; Platelet Aggregation Inhibitors; Polysaccharides; Prodrugs; Randomized Controlled Trials as Topic; Stents; Thrombosis; Ticlopidine; Time Factors; Venous Thrombosis

2005
Ximelagatran: direct thrombin inhibitor.
    Vascular health and risk management, 2006, Volume: 2, Issue:1

    Topics: Acute Disease; Administration, Oral; Anticoagulants; Atrial Fibrillation; Azetidines; Benzylamines; Heart Diseases; Hemostasis; Humans; Molecular Structure; Orthopedic Procedures; Patient Compliance; Patient Satisfaction; Platelet Aggregation; Prodrugs; Stroke; Syndrome; Thrombin; Thromboembolism; Treatment Outcome; Venous Thrombosis

2006
[Treatment of deep vein thrombosis. Current and future questions].
    Bulletin de l'Academie nationale de medecine, 2001, Volume: 185, Issue:8

    Topics: Administration, Oral; Anticoagulants; Azetidines; Benzylamines; Glycine; Hemorrhage; Heparin, Low-Molecular-Weight; Humans; Polysaccharides; Recurrence; Risk Factors; Venous Thrombosis

2001

Trials

7 trial(s) available for melagatran and Venous Thrombosis

ArticleYear
Pharmacokinetics, pharmacodynamics and clinical effects of the oral direct thrombin inhibitor ximelagatran in acute treatment of patients with pulmonary embolism and deep vein thrombosis.
    Thrombosis research, 2002, Aug-15, Volume: 107, Issue:3-4

    Topics: Administration, Oral; Adult; Aged; Azetidines; Benzylamines; Female; Fibrinolytic Agents; Glycine; Humans; Male; Middle Aged; Partial Thromboplastin Time; Pharmacokinetics; Prodrugs; Pulmonary Embolism; Thrombin; Treatment Outcome; Venous Thrombosis

2002
Direct thrombin inhibitor melagatran followed by oral ximelagatran in comparison with enoxaparin for prevention of venous thromboembolism after total hip or knee replacement.
    Thrombosis and haemostasis, 2003, Volume: 89, Issue:2

    Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Anticoagulants; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Azetidines; Benzylamines; Cause of Death; Double-Blind Method; Drug Administration Schedule; Enoxaparin; Female; Glycine; Hemorrhage; Humans; Injections, Subcutaneous; Male; Middle Aged; Postoperative Complications; Prodrugs; Prospective Studies; Pulmonary Embolism; Safety; Thrombin; Treatment Outcome; Venous Thrombosis

2003
Pharmacokinetics of melagatran and the effect on ex vivo coagulation time in orthopaedic surgery patients receiving subcutaneous melagatran and oral ximelagatran: a population model analysis.
    Clinical pharmacokinetics, 2003, Volume: 42, Issue:7

    Topics: Administration, Cutaneous; Administration, Oral; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Azetidines; Benzylamines; Biological Availability; Body Weight; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Glycine; Humans; Metabolic Clearance Rate; Partial Thromboplastin Time; Postoperative Complications; Sweden; Thromboembolism; Venous Thrombosis; Whole Blood Coagulation Time

2003
The direct thrombin inhibitor melagatran followed by oral ximelagatran compared with enoxaparin for the prevention of venous thromboembolism after total hip or knee replacement: the EXPRESS study.
    Journal of thrombosis and haemostasis : JTH, 2003, Volume: 1, Issue:12

    Topics: Adult; Aged; Aged, 80 and over; Anticoagulants; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Azetidines; Benzylamines; Double-Blind Method; Enoxaparin; Female; Glycine; Hemorrhage; Humans; Male; Middle Aged; Preoperative Care; Therapeutic Equivalency; Thrombin; Thromboembolism; Venous Thrombosis

2003
A dose-ranging study of the oral direct thrombin inhibitor, ximelagatran, and its subcutaneous form, melagatran, compared with dalteparin in the prophylaxis of thromboembolism after hip or knee replacement: METHRO I. MElagatran for THRombin inhibition in
    Thrombosis and haemostasis, 2002, Volume: 87, Issue:2

    Topics: Administration, Oral; Adolescent; Aged; Aged, 80 and over; Anticoagulants; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Azetidines; Benzylamines; Dalteparin; Female; Glycine; Humans; Incidence; Injections, Subcutaneous; Male; Middle Aged; Partial Thromboplastin Time; Postoperative Complications; Prodrugs; Safety; Sweden; Thrombin; Thromboembolism; Treatment Outcome; Venous Thrombosis

2002
Factor V Leiden (G1691A) and prothrombin gene G20210A mutations as potential risk factors for venous thromboembolism after total hip or total knee replacement surgery.
    Thrombosis and haemostasis, 2002, Volume: 87, Issue:4

    Topics: Activated Protein C Resistance; Adolescent; Adult; Aged; Aged, 80 and over; Anticoagulants; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Azetidines; Benzylamines; Dalteparin; DNA Mutational Analysis; Double-Blind Method; Europe; Factor V; Female; Genetic Predisposition to Disease; Genotype; Glycine; Humans; Male; Middle Aged; Postoperative Complications; Promoter Regions, Genetic; Prospective Studies; Prothrombin; Pulmonary Embolism; Risk Factors; Thrombophilia; Venous Thrombosis

2002
Prophylaxis of venous thromboembolism with subcutaneous melagatran in total hip or total knee replacement: results from Phase II studies.
    Thrombosis research, 2002, Mar-01, Volume: 105, Issue:5

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Azetidines; Benzylamines; Cyclodextrins; Female; Fibrinolytic Agents; Glycine; Hemorrhage; Humans; Injections, Subcutaneous; Male; Middle Aged; Partial Thromboplastin Time; Phlebography; Thromboembolism; Venous Thrombosis

2002

Other Studies

8 other study(ies) available for melagatran and Venous Thrombosis

ArticleYear
[Story of a predictable death: the end of vitamin K antagonists?].
    La Revue de medecine interne, 2010, Volume: 31, Issue:2

    Topics: Anticoagulants; Azetidines; Benzylamines; France; Hemorrhage; Humans; Pulmonary Embolism; Thromboembolism; Thrombosis; Venous Thrombosis; Vitamin K

2010
Antithrombotic and anticoagulant profiles of TAK-442, a novel factor Xa inhibitor, in a rabbit model of venous thrombosis.
    Journal of cardiovascular pharmacology, 2010, Volume: 56, Issue:2

    Topics: Animals; Anticoagulants; Azetidines; Benzylamines; Bleeding Time; Blood Coagulation; Blood Coagulation Tests; Dogs; Factor Xa Inhibitors; Fibrinolytic Agents; Humans; Macaca fascicularis; Male; Mice; Mice, Inbred ICR; Morpholines; Pyrazoles; Pyridones; Pyrimidinones; Rabbits; Rats; Rats, Sprague-Dawley; Rivaroxaban; Sulfones; Thiophenes; Thrombin; Venous Thrombosis

2010
Three vehicle formulations for melagatran, a direct thrombin inhibitor, evaluated in a vena cava thrombosis model in the rat.
    Biopharmaceutics & drug disposition, 2003, Volume: 24, Issue:6

    Topics: Animals; Antithrombins; Azetidines; Benzylamines; Chemistry, Pharmaceutical; Constriction, Pathologic; Cyclodextrins; Delayed-Action Preparations; Disease Models, Animal; Drug Evaluation, Preclinical; Endothelium, Vascular; Glycine; Injections, Subcutaneous; Male; Partial Thromboplastin Time; Pharmaceutical Vehicles; Poloxamer; Rats; Rats, Sprague-Dawley; Solutions; Sweden; Thrombin Time; Vena Cava, Inferior; Venous Thrombosis

2003
Prevention of venous thromboembolism after orthopedic surgery: the EXPRESS study.
    Journal of thrombosis and haemostasis : JTH, 2004, Volume: 2, Issue:11

    Topics: Anticoagulants; Azetidines; Benzylamines; Clinical Trials as Topic; Dissent and Disputes; Enoxaparin; Glycine; Humans; Orthopedic Procedures; Therapeutic Equivalency; Thromboembolism; Treatment Outcome; Venous Thrombosis

2004
The oral direct thrombin inhibitor, ximelagatran, an alternative for anticoagulant treatment during the puerperium and lactation.
    BJOG : an international journal of obstetrics and gynaecology, 2005, Volume: 112, Issue:5

    Topics: Administration, Oral; Adult; Anticoagulants; Azetidines; Benzylamines; Breast Feeding; Female; Glycine; Humans; Lactation; Milk, Human; Postpartum Period; Puerperal Disorders; Thrombin; Thromboembolism; Venous Thrombosis

2005
The effects of ximelagatran and warfarin on the prophylaxis of a caval vein thrombosis and bleeding in the anaesthetized rat.
    Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis, 2005, Volume: 16, Issue:4

    Topics: Animals; Azetidines; Benzylamines; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Glycine; Hemorrhage; Male; Rats; Rats, Sprague-Dawley; Venae Cavae; Venous Thrombosis; Warfarin

2005
Antithrombotic and anticoagulant effects of the direct thrombin inhibitor dabigatran, and its oral prodrug, dabigatran etexilate, in a rabbit model of venous thrombosis.
    Journal of thrombosis and haemostasis : JTH, 2007, Volume: 5, Issue:6

    Topics: Administration, Oral; Animals; Anticoagulants; Azetidines; Benzimidazoles; Benzylamines; Dabigatran; Disease Models, Animal; Dose-Response Relationship, Drug; Fibrinolytic Agents; Heparin; Hirudin Therapy; Injections, Intravenous; Male; Partial Thromboplastin Time; Prodrugs; Pyridines; Rabbits; Venous Thrombosis

2007
[New thrombolytic agents].
    Medizinische Monatsschrift fur Pharmazeuten, 2001, Volume: 24, Issue:2

    Topics: Anticoagulants; Azetidines; Benzylamines; Fibrinolytic Agents; Glycine; Heparin; Humans; Thrombosis; Venous Thrombosis

2001