Page last updated: 2024-09-05

melagatran and Thromboembolism

melagatran has been researched along with Thromboembolism in 24 studies

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's23 (95.83)29.6817
2010's1 (4.17)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bergmann, JF; Lloret Linares, C1
Bergqvist, D; Bylock, A; Dahl, OE; Eriksson, BI; Eriksson, UG; Frison, L; Gustafsson, D; Kälebo, P; Lindbratt, S; Welin, L1
Eriksson, BI1
Haas, S1
Eriksson, BI; Eriksson, UG; Frison, L; Gisleskog, PO; Gustafsson, D; Hamrén, B; Karlsson, MO; Mandema, JW; Wählby, U1
Drouet, L1
Agnelli, G; Andersson, M; Cohen, AT; Dahl, OE; Eriksson, BI; Eskilson, C; Freij, A; Kälebo, P; Lassen, MR; Mouret, P; Panfilov, S; Rosencher, N1
Evans, HC; Faulds, D; Perry, CM1
Al-Mousa, EN; Salam, AM1
Cimminiello, C; Planès, A; Samama, MM1
Andersen, JC1
Petersen, P1
Bereznicki, LR; Jackson, SL; Peterson, GM1
Eriksson, UG; Hellgren, M; Johansson, S; Wåhlander, K1
Auboyer, C; Laporte, S; Mismetti, P; Molliex, S; Zufferey, P1
Nielsen, JD1
Hering, D; Horstkotte, D; Piper, C1
Caronia, A; Montalto, S; Novo, S; Puccio, D; Valerio, MC; Ventimiglia, A1
Brighton, TA; Ho, SJ1
Hamner, CE; Lewin, M; Potter, DD; Schaff, HV; Sundt, TM; Thompson, JL1
Fleischer, K; Gulba, DC; Lankes, W1
Arfwidsson, AC; Bylock, A; Eriksson, BI; Eriksson, UG; Fager, G; Frison, L; Gustafsson, D; Kälebo, P1
Ahnfelt, L; Arfwidsson, AC; Björkström, S; Elvander, CS; Eriksson, BI; Eriksson, UG; Folestad, A; Frison, L; Kälebo, P; Ogren, M; Sjöstedt, A1

Reviews

13 review(s) available for melagatran and Thromboembolism

ArticleYear
Clinical experience of melagatran/ximelagatran in major orthopaedic surgery.
    Thrombosis research, 2003, Jul-15, Volume: 109 Suppl 1

    Topics: Azetidines; Benzylamines; Clinical Trials as Topic; Glycine; Humans; Orthopedic Procedures; Thromboembolism; Thrombosis; Treatment Outcome

2003
Medical indications and considerations for future clinical decision making.
    Thrombosis research, 2003, Jul-15, Volume: 109 Suppl 1

    Topics: Azetidines; Benzylamines; Cardiovascular Diseases; Clinical Protocols; Clinical Trials as Topic; Glycine; Humans; Thromboembolism

2003
[Treatment and prevention of venous thromboembolic events: present and future antithrombotic agents].
    Bulletin de l'Academie nationale de medecine, 2003, Volume: 187, Issue:1

    Topics: Administration, Oral; Azetidines; Benzylamines; Clinical Trials as Topic; Coronary Thrombosis; Factor Xa Inhibitors; Fibrinolytic Agents; Fondaparinux; Glycine; Hirudin Therapy; Humans; Orthopedics; Polysaccharides; Prodrugs; Prothrombin; Research; Thrombin; Thromboembolism; Time Factors; Venous Thrombosis

2003
Ximelagatran/Melagatran: a review of its use in the prevention of venous thromboembolism in orthopaedic surgery.
    Drugs, 2004, Volume: 64, Issue:6

    Topics: Anticoagulants; Azetidines; Benzylamines; Drug Interactions; Drug Therapy, Combination; Enoxaparin; Glycine; Humans; Orthopedic Procedures; Randomized Controlled Trials as Topic; Thrombin; Thromboembolism; Venous Thrombosis; Warfarin

2004
The therapeutic potential of ximelagatran to become the anticoagulant of choice in medicine: a review of recently completed clinical trials.
    Expert opinion on pharmacotherapy, 2004, Volume: 5, Issue:6

    Topics: Anticoagulants; Atrial Fibrillation; Azetidines; Benzylamines; Clinical Trials as Topic; Coronary Artery Disease; Drug Therapy, Combination; Glycine; Humans; Prodrugs; Stroke; Thrombin; Thromboembolism; Venous Thrombosis

2004
Advances in anticoagulation therapy: the role of selective inhibitors of factor Xa and thrombin in thromboprophylaxis after major orthopedic surgery.
    Seminars in thrombosis and hemostasis, 2004, Volume: 30, Issue:6

    Topics: Anticoagulants; Azetidines; Benzylamines; Clinical Trials as Topic; Factor Xa Inhibitors; Fondaparinux; Glycine; Heparin; Heparin, Low-Molecular-Weight; Humans; Models, Biological; Orthopedics; Polysaccharides; Postoperative Complications; Thromboembolism; Thrombolytic Therapy

2004
Ximelagatran--a promising new drug in thromboembolic disorders.
    Current pharmaceutical design, 2005, Volume: 11, Issue:4

    Topics: Administration, Oral; Anticoagulants; Azetidines; Benzylamines; Glycine; Humans; Prodrugs; Randomized Controlled Trials as Topic; Stroke; Thrombin; Thromboembolism; Venous Thrombosis

2005
Ximelagatran and melagatran vs. low-molecular-weight heparin in major orthopedic surgery: relationship between efficacy and safety and timing of initial administration.
    Journal of thrombosis and haemostasis : JTH, 2005, Volume: 3, Issue:5

    Topics: Anticoagulants; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Azetidines; Benzylamines; Fibrinolytic Agents; Glycine; Heparin, Low-Molecular-Weight; Humans; Meta-Analysis as Topic; Orthopedics; Random Allocation; Regression Analysis; Risk; Risk Factors; Thrombin; Thromboembolism

2005
[Thromboprophylaxis in hip and knee arthroplasty. Are the new anticoagulants better than those previously used?].
    Ugeskrift for laeger, 2005, May-23, Volume: 167, Issue:21

    Topics: Anticoagulants; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Azetidines; Benzylamines; Clinical Trials, Phase III as Topic; Fibrinolytic Agents; Fondaparinux; Glycine; Humans; Polysaccharides; Postoperative Complications; Pulmonary Embolism; Thromboembolism; Venous Thrombosis

2005
Drug insight: an overview of current anticoagulation therapy after heart valve replacement.
    Nature clinical practice. Cardiovascular medicine, 2005, Volume: 2, Issue:8

    Topics: Anticoagulants; Azetidines; Benzylamines; Glycine; Heart Valve Prosthesis; Heparin, Low-Molecular-Weight; Humans; Thromboembolism; Vitamin K

2005
[Clinical use of a new class of anticoagulant drugs: the direct thrombin inhibitors].
    Giornale italiano di cardiologia (2006), 2006, Volume: 7, Issue:11

    Topics: Anticoagulants; Antithrombins; Azetidines; Benzylamines; Clinical Trials as Topic; Drug Therapy, Combination; Fibrinolytic Agents; Hirudins; Humans; Peptide Fragments; Recombinant Proteins; Thromboembolism; Treatment Outcome

2006
Ximelagatran: direct thrombin inhibitor.
    Vascular health and risk management, 2006, Volume: 2, Issue:1

    Topics: Acute Disease; Administration, Oral; Anticoagulants; Atrial Fibrillation; Azetidines; Benzylamines; Heart Diseases; Hemostasis; Humans; Molecular Structure; Orthopedic Procedures; Patient Compliance; Patient Satisfaction; Platelet Aggregation; Prodrugs; Stroke; Syndrome; Thrombin; Thromboembolism; Treatment Outcome; Venous Thrombosis

2006
[Direct thrombin antagonists].
    Herz, 2001, Volume: 26 Suppl 1

    Topics: Acute Disease; Angina, Unstable; Angioplasty, Balloon, Coronary; Animals; Anticoagulants; Antithrombins; Arginine; Azetidines; Benzylamines; Fibrinolytic Agents; Glycine; Hirudin Therapy; Hirudins; Humans; Myocardial Infarction; Peptide Fragments; Pipecolic Acids; Platelet Aggregation Inhibitors; Rabbits; Recombinant Proteins; Sulfonamides; Syndrome; Thrombin; Thromboembolism; Thrombosis; Time Factors

2001

Trials

6 trial(s) available for melagatran and Thromboembolism

ArticleYear
Ximelagatran and melagatran compared with dalteparin for prevention of venous thromboembolism after total hip or knee replacement: the METHRO II randomised trial.
    Lancet (London, England), 2002, Nov-09, Volume: 360, Issue:9344

    Topics: Adult; Aged; Anticoagulants; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Azetidines; Benzylamines; Dalteparin; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Female; Glycine; Humans; Male; Middle Aged; Postoperative Complications; Prodrugs; Thromboembolism

2002
Clinical experience of melagatran/ximelagatran in major orthopaedic surgery.
    Thrombosis research, 2003, Jul-15, Volume: 109 Suppl 1

    Topics: Azetidines; Benzylamines; Clinical Trials as Topic; Glycine; Humans; Orthopedic Procedures; Thromboembolism; Thrombosis; Treatment Outcome

2003
Pharmacokinetics of melagatran and the effect on ex vivo coagulation time in orthopaedic surgery patients receiving subcutaneous melagatran and oral ximelagatran: a population model analysis.
    Clinical pharmacokinetics, 2003, Volume: 42, Issue:7

    Topics: Administration, Cutaneous; Administration, Oral; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Azetidines; Benzylamines; Biological Availability; Body Weight; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Glycine; Humans; Metabolic Clearance Rate; Partial Thromboplastin Time; Postoperative Complications; Sweden; Thromboembolism; Venous Thrombosis; Whole Blood Coagulation Time

2003
The direct thrombin inhibitor melagatran followed by oral ximelagatran compared with enoxaparin for the prevention of venous thromboembolism after total hip or knee replacement: the EXPRESS study.
    Journal of thrombosis and haemostasis : JTH, 2003, Volume: 1, Issue:12

    Topics: Adult; Aged; Aged, 80 and over; Anticoagulants; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Azetidines; Benzylamines; Double-Blind Method; Enoxaparin; Female; Glycine; Hemorrhage; Humans; Male; Middle Aged; Preoperative Care; Therapeutic Equivalency; Thrombin; Thromboembolism; Venous Thrombosis

2003
A dose-ranging study of the oral direct thrombin inhibitor, ximelagatran, and its subcutaneous form, melagatran, compared with dalteparin in the prophylaxis of thromboembolism after hip or knee replacement: METHRO I. MElagatran for THRombin inhibition in
    Thrombosis and haemostasis, 2002, Volume: 87, Issue:2

    Topics: Administration, Oral; Adolescent; Aged; Aged, 80 and over; Anticoagulants; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Azetidines; Benzylamines; Dalteparin; Female; Glycine; Humans; Incidence; Injections, Subcutaneous; Male; Middle Aged; Partial Thromboplastin Time; Postoperative Complications; Prodrugs; Safety; Sweden; Thrombin; Thromboembolism; Treatment Outcome; Venous Thrombosis

2002
Prophylaxis of venous thromboembolism with subcutaneous melagatran in total hip or total knee replacement: results from Phase II studies.
    Thrombosis research, 2002, Mar-01, Volume: 105, Issue:5

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Azetidines; Benzylamines; Cyclodextrins; Female; Fibrinolytic Agents; Glycine; Hemorrhage; Humans; Injections, Subcutaneous; Male; Middle Aged; Partial Thromboplastin Time; Phlebography; Thromboembolism; Venous Thrombosis

2002

Other Studies

6 other study(ies) available for melagatran and Thromboembolism

ArticleYear
[Story of a predictable death: the end of vitamin K antagonists?].
    La Revue de medecine interne, 2010, Volume: 31, Issue:2

    Topics: Anticoagulants; Azetidines; Benzylamines; France; Hemorrhage; Humans; Pulmonary Embolism; Thromboembolism; Thrombosis; Venous Thrombosis; Vitamin K

2010
[The first oral thrombin inhibitor. Competition to heparins and marcumar?].
    MMW Fortschritte der Medizin, 2003, Mar-06, Volume: 145, Issue:10

    Topics: Administration, Oral; Anticoagulants; Azetidines; Benzylamines; Clinical Trials as Topic; Enoxaparin; Fibrinolytic Agents; Glycine; Humans; Phenprocoumon; Placebos; Prodrugs; Thrombin; Thromboembolism; Thrombosis; Time Factors

2003
Prevention of venous thromboembolism after orthopedic surgery: the EXPRESS study.
    Journal of thrombosis and haemostasis : JTH, 2004, Volume: 2, Issue:11

    Topics: Anticoagulants; Azetidines; Benzylamines; Clinical Trials as Topic; Dissent and Disputes; Enoxaparin; Glycine; Humans; Orthopedic Procedures; Therapeutic Equivalency; Thromboembolism; Treatment Outcome; Venous Thrombosis

2004
The direct thrombin inhibitor melagatran/ximelagatran.
    The Medical journal of Australia, 2005, Mar-07, Volume: 182, Issue:5

    Topics: Anticoagulants; Atrial Fibrillation; Azetidines; Benzylamines; Cost-Benefit Analysis; Drug Costs; Humans; Safety; Thrombin; Thromboembolism; Warfarin

2005
The oral direct thrombin inhibitor, ximelagatran, an alternative for anticoagulant treatment during the puerperium and lactation.
    BJOG : an international journal of obstetrics and gynaecology, 2005, Volume: 112, Issue:5

    Topics: Administration, Oral; Adult; Anticoagulants; Azetidines; Benzylamines; Breast Feeding; Female; Glycine; Humans; Lactation; Milk, Human; Postpartum Period; Puerperal Disorders; Thrombin; Thromboembolism; Venous Thrombosis

2005
Melagatran for thromboprophylaxis after mechanical valve implantation: results in a heterotopic porcine model.
    The Journal of thoracic and cardiovascular surgery, 2007, Volume: 134, Issue:2

    Topics: Animals; Anticoagulants; Azetidines; Benzylamines; Dalteparin; Heart Valve Prosthesis Implantation; Random Allocation; Statistics, Nonparametric; Swine; Thromboembolism

2007