Page last updated: 2024-09-05

melagatran and Hemorrhage

melagatran has been researched along with Hemorrhage in 12 studies

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's10 (83.33)29.6817
2010's1 (8.33)24.3611
2020's1 (8.33)2.80

Authors

AuthorsStudies
Pilgram, O; Steinmetzer, T; Wenzel, BM; Wiedemeyer, SJA1
Bergmann, JF; Lloret Linares, C1
Agnelli, G; Cohen, AT; Dahl, OE; Eriksson, BI; Eskilson, C; Frison, L; Mouret, P; Nylander, I; Ogren, M; Rosencher, N1
Carlsson, S; Johnston, M; Klement, P; Liao, P; Rak, J; Stafford, A; Vlasin, M; Weitz, JI1
Eriksson, UG; Johansson, S; Larson, G; Larsson, M; Ohlsson, L; Wåhlander, K1
Agnelli, G; Andersson, M; Cohen, AT; Dahl, OE; Eriksson, BI; Eskilson, C; Freij, A; Kälebo, P; Lassen, MR; Mouret, P; Panfilov, S; Rosencher, N1
Bijsterveld, NR; Keller, TT; Levi, M1
Carlsson, S; Elg, M1
Carlsson, S; Elg, M; Gustafsson, D1
Bode, C; Darius, H; Diehm, C; Encke, A; Gulba, DC; Haas, S; Hacke, W; Puhl, W; Quante, M; Riess, H; Scharf, R; Schellong, S; Schrör, T; Schulte, KL; Tebbe, U; Van Aken, H1
Fiessinger, JN1
Ahnfelt, L; Arfwidsson, AC; Björkström, S; Elvander, CS; Eriksson, BI; Eriksson, UG; Folestad, A; Frison, L; Kälebo, P; Ogren, M; Sjöstedt, A1

Reviews

3 review(s) available for melagatran and Hemorrhage

ArticleYear
Recombinant factor VIIa as an antidote for anticoagulant treatment.
    Seminars in hematology, 2004, Volume: 41, Issue:1 Suppl 1

    Topics: Anticoagulants; Azetidines; Benzylamines; Factor VII; Factor VIIa; Glycine; Helminth Proteins; Hemorrhage; Humans; Platelet Aggregation Inhibitors; Recombinant Proteins

2004
Anticoagulation: the present and future.
    Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis, 2001, Volume: 7, Issue:3

    Topics: Administration, Oral; Amino Acid Chloromethyl Ketones; Anticoagulants; Arginine; Azetidines; Benzylamines; Binding Sites; Biological Availability; Blood Coagulation; Comorbidity; Coumarins; Drug Design; Embolism; Female; Forecasting; Glycine; Guanidines; Heart Diseases; Hemorrhage; Heparin; Heparin, Low-Molecular-Weight; Hirudin Therapy; Humans; Neoplasms; Pipecolic Acids; Pregnancy; Pregnancy Complications, Hematologic; Prodrugs; Safety; Serine; Stroke; Sulfonamides; Thrombin; Thrombophilia; Thrombosis

2001
[Treatment of deep vein thrombosis. Current and future questions].
    Bulletin de l'Academie nationale de medecine, 2001, Volume: 185, Issue:8

    Topics: Administration, Oral; Anticoagulants; Azetidines; Benzylamines; Glycine; Hemorrhage; Heparin, Low-Molecular-Weight; Humans; Polysaccharides; Recurrence; Risk Factors; Venous Thrombosis

2001

Trials

4 trial(s) available for melagatran and Hemorrhage

ArticleYear
Direct thrombin inhibitor melagatran followed by oral ximelagatran in comparison with enoxaparin for prevention of venous thromboembolism after total hip or knee replacement.
    Thrombosis and haemostasis, 2003, Volume: 89, Issue:2

    Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Anticoagulants; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Azetidines; Benzylamines; Cause of Death; Double-Blind Method; Drug Administration Schedule; Enoxaparin; Female; Glycine; Hemorrhage; Humans; Injections, Subcutaneous; Male; Middle Aged; Postoperative Complications; Prodrugs; Prospective Studies; Pulmonary Embolism; Safety; Thrombin; Treatment Outcome; Venous Thrombosis

2003
Pharmacokinetics and anticoagulant effect of the direct thrombin inhibitor melagatran following subcutaneous administration to healthy young men.
    Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis, 2003, Volume: 14, Issue:7

    Topics: Adult; Anticoagulants; Area Under Curve; Azetidines; Benzylamines; Biological Availability; Blood Coagulation; Blood Coagulation Tests; Dose-Response Relationship, Drug; Glycine; Half-Life; Hemorrhage; Humans; Injections, Subcutaneous; Male; Pharmacokinetics; Thrombin

2003
The direct thrombin inhibitor melagatran followed by oral ximelagatran compared with enoxaparin for the prevention of venous thromboembolism after total hip or knee replacement: the EXPRESS study.
    Journal of thrombosis and haemostasis : JTH, 2003, Volume: 1, Issue:12

    Topics: Adult; Aged; Aged, 80 and over; Anticoagulants; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Azetidines; Benzylamines; Double-Blind Method; Enoxaparin; Female; Glycine; Hemorrhage; Humans; Male; Middle Aged; Preoperative Care; Therapeutic Equivalency; Thrombin; Thromboembolism; Venous Thrombosis

2003
Prophylaxis of venous thromboembolism with subcutaneous melagatran in total hip or total knee replacement: results from Phase II studies.
    Thrombosis research, 2002, Mar-01, Volume: 105, Issue:5

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Azetidines; Benzylamines; Cyclodextrins; Female; Fibrinolytic Agents; Glycine; Hemorrhage; Humans; Injections, Subcutaneous; Male; Middle Aged; Partial Thromboplastin Time; Phlebography; Thromboembolism; Venous Thrombosis

2002

Other Studies

5 other study(ies) available for melagatran and Hemorrhage

ArticleYear
Fibrinolysis Inhibitors: Potential Drugs for the Treatment and Prevention of Bleeding.
    Journal of medicinal chemistry, 2020, 02-27, Volume: 63, Issue:4

    Topics: Animals; Antifibrinolytic Agents; Catalytic Domain; Crystallography, X-Ray; Fibrinolysin; Fibrinolysis; Hemorrhage; Humans; Ligands; Molecular Structure; Plasminogen; Protein Binding; Protein Domains

2020
[Story of a predictable death: the end of vitamin K antagonists?].
    La Revue de medecine interne, 2010, Volume: 31, Issue:2

    Topics: Anticoagulants; Azetidines; Benzylamines; France; Hemorrhage; Humans; Pulmonary Embolism; Thromboembolism; Thrombosis; Venous Thrombosis; Vitamin K

2010
The benefit-to-risk profile of melagatran is superior to that of hirudin in a rabbit arterial thrombosis prevention and bleeding model.
    Journal of thrombosis and haemostasis : JTH, 2003, Volume: 1, Issue:3

    Topics: Animals; Arteries; Azetidines; Benzylamines; Dose-Response Relationship, Drug; Fibrin; Fibrinolytic Agents; Glycine; Hemorrhage; Hirudin Therapy; Hirudins; Male; Rabbits; Risk Assessment; Thrombin; Thrombosis

2003
The effects of ximelagatran and warfarin on the prophylaxis of a caval vein thrombosis and bleeding in the anaesthetized rat.
    Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis, 2005, Volume: 16, Issue:4

    Topics: Animals; Azetidines; Benzylamines; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Glycine; Hemorrhage; Male; Rats; Rats, Sprague-Dawley; Venae Cavae; Venous Thrombosis; Warfarin

2005
Effects of agents, used to treat bleeding disorders, on bleeding time prolonged by a very high dose of a direct thrombin inhibitor in anesthesized rats and rabbits.
    Thrombosis research, 2001, Feb-01, Volume: 101, Issue:3

    Topics: Animals; Anticoagulants; Azetidines; Benzylamines; Bleeding Time; Blood Coagulation Factors; Factor IX; Factor VIIa; Factor VIII; Glycine; Hemorrhage; Humans; Rabbits; Rats; Thrombin; von Willebrand Factor

2001