melagatran has been researched along with Disease Models, Animal in 10 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (10.00) | 18.2507 |
| 2000's | 7 (70.00) | 29.6817 |
| 2010's | 2 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Morishima, Y; Shibano, T; Shirasaki, Y | 1 |
| Ding, X; Shuaib, A; Wang, CX | 1 |
| Bunnett, NW; Cattaruzza, F; Ceppa, EP; Grady, EF; Grahn, S; Kirkwood, KS; Knecht, W; Lyo, V; Peterson, A | 1 |
| Börjesson, I; Carlsson, S; Elg, M | 1 |
| Elg, M; Gustafsson, D | 1 |
| Carlsson, S; Elg, M | 1 |
| Furugohri, T; Honda, Y; Isobe, K; Matsumoto, C; Muramatsu, S; Shiozaki, Y; Sugiyama, N | 1 |
| Driscoll, E; Hong, TT; Huang, J; Lucchesi, BR | 1 |
| Hauel, N; Priepke, H; Ries, UJ; Stassen, JM; Wienen, W | 1 |
| Carlsson, S; Eriksson, BI; Halvarsson, M; Mattsson, C; Risberg, B | 1 |
10 other study(ies) available for melagatran and Disease Models, Animal
| Article | Year |
|---|---|
Comparison of the effect of edoxaban, a direct factor Xa inhibitor, with a direct thrombin inhibitor, melagatran, and heparin on intracerebral hemorrhage induced by collagenase in rats.
Topics: Animals; Anticoagulants; Antithrombins; Azetidines; Benzylamines; Cerebral Hemorrhage; Collagenases; Disease Models, Animal; Factor Xa Inhibitors; Heparin; Male; Pyridines; Rats; Rats, Wistar; Thiazoles | 2014 |
Treatment with melagatran alone or in combination with thrombolytic therapy reduced ischemic brain injury.
Topics: Animals; Anticoagulants; Azetidines; Benzylamines; Brain Ischemia; Cerebral Arteries; Cerebrovascular Circulation; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Fibrinolytic Agents; Intracranial Embolism; Male; Microcirculation; Neuroprotective Agents; Rats; Rats, Wistar; Thrombolytic Therapy; Tissue Plasminogen Activator; Treatment Outcome | 2008 |
Serine proteases mediate inflammatory pain in acute pancreatitis.
Topics: Abdominal Pain; Acute Disease; Amylases; Analgesics; Animals; Azetidines; Benzylamines; Ceruletide; Disease Models, Animal; Enteropeptidase; Enzyme Activation; Humans; Kinetics; Male; Pain Measurement; Pancreas; Pancreatitis; Peroxidase; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Receptor, PAR-2; Recombinant Proteins; Signal Transduction; Soybean Proteins; Spinal Cord; Trypsin; Trypsin Inhibitors | 2011 |
Three vehicle formulations for melagatran, a direct thrombin inhibitor, evaluated in a vena cava thrombosis model in the rat.
Topics: Animals; Antithrombins; Azetidines; Benzylamines; Chemistry, Pharmaceutical; Constriction, Pathologic; Cyclodextrins; Delayed-Action Preparations; Disease Models, Animal; Drug Evaluation, Preclinical; Endothelium, Vascular; Glycine; Injections, Subcutaneous; Male; Partial Thromboplastin Time; Pharmaceutical Vehicles; Poloxamer; Rats; Rats, Sprague-Dawley; Solutions; Sweden; Thrombin Time; Vena Cava, Inferior; Venous Thrombosis | 2003 |
A combination of a thrombin inhibitor and dexamethasone prevents the development of experimental disseminated intravascular coagulation in rats.
Topics: Animals; Anti-Inflammatory Agents; Anticoagulants; Antineoplastic Combined Chemotherapy Protocols; Azetidines; Benzylamines; Blood Coagulation; Dexamethasone; Disease Models, Animal; Disseminated Intravascular Coagulation; Humans; Male; Rats; Rats, Sprague-Dawley; Thrombin; Treatment Outcome | 2006 |
The effects of ximelagatran and warfarin on the prophylaxis of a caval vein thrombosis and bleeding in the anaesthetized rat.
Topics: Animals; Azetidines; Benzylamines; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Glycine; Hemorrhage; Male; Rats; Rats, Sprague-Dawley; Venae Cavae; Venous Thrombosis; Warfarin | 2005 |
Different antithrombotic properties of factor Xa inhibitor and thrombin inhibitor in rat thrombosis models.
Topics: Animals; Azetidines; Benzylamines; Blood Coagulation; Disease Models, Animal; Dose-Response Relationship, Drug; Factor Xa Inhibitors; Fibrinolytic Agents; Glycine; Male; Naphthalenes; Propionates; Rats; Rats, Wistar; Thrombin; Thromboplastin; Thrombosis | 2005 |
The antithrombotic effect of melagatran in combination with clopidogrel and/or aspirin (carotid artery primary thrombosis study).
Topics: Animals; Aspirin; Azetidines; Benzylamines; Bleeding Time; Blood Flow Velocity; Blood Pressure; Carotid Artery Thrombosis; Carotid Artery, Common; Clopidogrel; Disease Models, Animal; Dogs; Drug Therapy, Combination; Female; Fibrinolytic Agents; Heart Rate; Male; Partial Thromboplastin Time; Platelet Aggregation; Platelet Aggregation Inhibitors; Random Allocation; Ticlopidine; Tongue; Vascular Patency | 2005 |
Antithrombotic and anticoagulant effects of the direct thrombin inhibitor dabigatran, and its oral prodrug, dabigatran etexilate, in a rabbit model of venous thrombosis.
Topics: Administration, Oral; Animals; Anticoagulants; Azetidines; Benzimidazoles; Benzylamines; Dabigatran; Disease Models, Animal; Dose-Response Relationship, Drug; Fibrinolytic Agents; Heparin; Hirudin Therapy; Injections, Intravenous; Male; Partial Thromboplastin Time; Prodrugs; Pyridines; Rabbits; Venous Thrombosis | 2007 |
Antithrombotic effect of two low molecular weight thrombin inhibitors and a low-molecular weight heparin in a caval vein thrombosis model in the rat.
Topics: Animals; Azetidines; Benzylamines; Dalteparin; Disease Models, Animal; Fibrinolytic Agents; Glycine; Heparin, Low-Molecular-Weight; Infusions, Intravenous; Injections, Intravenous; Male; Piperidines; Rats; Rats, Wistar; Thrombin; Thrombophlebitis; Vena Cava, Inferior | 1997 |