meglutol has been researched along with Nervous System Disorders in 2 studies
Meglutol: An antilipemic agent which lowers cholesterol, triglycerides, serum beta-lipoproteins and phospholipids. It acts by interfering with the enzymatic steps involved in the conversion of acetate to hydroxymethylglutaryl coenzyme A as well as inhibiting the activity of HYDROXYMETHYLGLUTARYL COA REDUCTASES which is the rate limiting enzyme in the biosynthesis of cholesterol.
3-hydroxy-3-methylglutaric acid : A dicarboxylic acid that is glutaric acid in which one of the two hydrogens at position 3 is substituted by a hydroxy group, while the other is substituted by a methyl group. It has been found to accumulate in urine of patients suffering from HMG-CoA lyase (3-hydroxy-3-methylglutaryl-CoA lyase, EC 4.1.3.4) deficiency. It occurs as a plant metabolite in Crotalaria dura.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ozand, PT | 1 |
| Nyhan, WL | 1 |
| al Aqeel, A | 1 |
| Christodoulou, J | 1 |
| Sheffer, RN | 1 |
| Zlotogora, J | 1 |
| Elpeleg, ON | 1 |
| Raz, J | 1 |
| Ben-Ezra, D | 1 |
2 other studies available for meglutol and Nervous System Disorders
| Article | Year |
|---|---|
Malonic aciduria.
Topics: Acidosis; Carboxy-Lyases; Fibroblasts; Glutaryl-CoA Dehydrogenase; Humans; Infant; Infant, Newborn; | 1994 |
Behr's syndrome and 3-methylglutaconic aciduria.
Topics: Child; Child, Preschool; Female; Glutarates; Humans; Infant; Jews; Male; Meglutol; Nervous System Di | 1992 |