Page last updated: 2024-10-21

meglutol and Diabetes Mellitus, Gestational

meglutol has been researched along with Diabetes Mellitus, Gestational in 1 studies

Meglutol: An antilipemic agent which lowers cholesterol, triglycerides, serum beta-lipoproteins and phospholipids. It acts by interfering with the enzymatic steps involved in the conversion of acetate to hydroxymethylglutaryl coenzyme A as well as inhibiting the activity of HYDROXYMETHYLGLUTARYL COA REDUCTASES which is the rate limiting enzyme in the biosynthesis of cholesterol.
3-hydroxy-3-methylglutaric acid : A dicarboxylic acid that is glutaric acid in which one of the two hydrogens at position 3 is substituted by a hydroxy group, while the other is substituted by a methyl group. It has been found to accumulate in urine of patients suffering from HMG-CoA lyase (3-hydroxy-3-methylglutaryl-CoA lyase, EC 4.1.3.4) deficiency. It occurs as a plant metabolite in Crotalaria dura.

Research Excerpts

ExcerptRelevanceReference
"Aberrant fetal programming in gestational diabetes mellitus seems to increase the risk of obesity, type 2 diabetes, and cardiovascular disease."1.62Early pregnancy metabolites predict gestational diabetes mellitus: implications for fetal programming. ( Gornbein, JA; Koos, BJ, 2021)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's1 (100.00)2.80

Authors

AuthorsStudies
Koos, BJ1
Gornbein, JA1

Other Studies

1 other study available for meglutol and Diabetes Mellitus, Gestational

ArticleYear
Early pregnancy metabolites predict gestational diabetes mellitus: implications for fetal programming.
    American journal of obstetrics and gynecology, 2021, Volume: 224, Issue:2

    Topics: Adult; Alanine; Arginine; Carnitine; Case-Control Studies; Diabetes, Gestational; Diet Therapy; Dopa

2021