meglutol has been researched along with Aprosodia in 2 studies
Meglutol: An antilipemic agent which lowers cholesterol, triglycerides, serum beta-lipoproteins and phospholipids. It acts by interfering with the enzymatic steps involved in the conversion of acetate to hydroxymethylglutaryl coenzyme A as well as inhibiting the activity of HYDROXYMETHYLGLUTARYL COA REDUCTASES which is the rate limiting enzyme in the biosynthesis of cholesterol.
3-hydroxy-3-methylglutaric acid : A dicarboxylic acid that is glutaric acid in which one of the two hydrogens at position 3 is substituted by a hydroxy group, while the other is substituted by a methyl group. It has been found to accumulate in urine of patients suffering from HMG-CoA lyase (3-hydroxy-3-methylglutaryl-CoA lyase, EC 4.1.3.4) deficiency. It occurs as a plant metabolite in Crotalaria dura.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (50.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Duran, M | 1 |
| Beemer, FA | 1 |
| Tibosch, AS | 1 |
| Bruinvis, L | 1 |
| Ketting, D | 1 |
| Wadman, SK | 1 |
| Ensenauer, R | 1 |
| Müller, CB | 1 |
| Schwab, KO | 1 |
| Gibson, KM | 1 |
| Brandis, M | 1 |
| Lehnert, W | 1 |
2 other studies available for meglutol and Aprosodia
| Article | Year |
|---|---|
Inherited 3-methylglutaconic aciduria in two brothers--another defect of leucine metabolism.
Topics: Amino Acid Metabolism, Inborn Errors; Child; Child, Preschool; Glutarates; Humans; Hydro-Lyases; Leu | 1982 |
3-Methylglutaconyl-CoA hydratase deficiency: a new patient with speech retardation as the leading sign.
Topics: Amino Acid Metabolism, Inborn Errors; Cells, Cultured; Diet, Protein-Restricted; Fibroblasts; Glutar | 2000 |