meglutol has been researched along with Alloxan Diabetes in 2 studies
Meglutol: An antilipemic agent which lowers cholesterol, triglycerides, serum beta-lipoproteins and phospholipids. It acts by interfering with the enzymatic steps involved in the conversion of acetate to hydroxymethylglutaryl coenzyme A as well as inhibiting the activity of HYDROXYMETHYLGLUTARYL COA REDUCTASES which is the rate limiting enzyme in the biosynthesis of cholesterol.
3-hydroxy-3-methylglutaric acid : A dicarboxylic acid that is glutaric acid in which one of the two hydrogens at position 3 is substituted by a hydroxy group, while the other is substituted by a methyl group. It has been found to accumulate in urine of patients suffering from HMG-CoA lyase (3-hydroxy-3-methylglutaryl-CoA lyase, EC 4.1.3.4) deficiency. It occurs as a plant metabolite in Crotalaria dura.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Deana, R | 2 |
| Lippe, G | 1 |
| Galzigna, L | 2 |
| Francesconi, M | 1 |
| Plebani, M | 1 |
| Furlanetto, V | 1 |
| Fabris, R | 1 |
2 other studies available for meglutol and Alloxan Diabetes
| Article | Year |
|---|---|
Urinary excretion of 3-hydroxy-3-methylglutaric acid in the diabetic condition.
Topics: Acetoacetates; Adult; Animals; Chromatography, Gas; Diabetes Mellitus; Diabetes Mellitus, Experiment | 1982 |
Effect of 3-hydroxy-3-methylglutarate treatment on plasma ketone bodies, triglycerides, and HDL-cholesterol in streptozotocin-diabetic rats.
Topics: Animals; Blood Glucose; Cholesterol, HDL; Diabetes Mellitus, Experimental; Female; Glutarates; Keton | 1987 |