meglutol has been researched along with Acute Disease in 2 studies
Meglutol: An antilipemic agent which lowers cholesterol, triglycerides, serum beta-lipoproteins and phospholipids. It acts by interfering with the enzymatic steps involved in the conversion of acetate to hydroxymethylglutaryl coenzyme A as well as inhibiting the activity of HYDROXYMETHYLGLUTARYL COA REDUCTASES which is the rate limiting enzyme in the biosynthesis of cholesterol.
3-hydroxy-3-methylglutaric acid : A dicarboxylic acid that is glutaric acid in which one of the two hydrogens at position 3 is substituted by a hydroxy group, while the other is substituted by a methyl group. It has been found to accumulate in urine of patients suffering from HMG-CoA lyase (3-hydroxy-3-methylglutaryl-CoA lyase, EC 4.1.3.4) deficiency. It occurs as a plant metabolite in Crotalaria dura.
Acute Disease: Disease having a short and relatively severe course.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Santarelli, F | 1 |
| Cassanello, M | 1 |
| Enea, A | 1 |
| Poma, F | 1 |
| D'Onofrio, V | 1 |
| Guala, G | 1 |
| Garrone, G | 1 |
| Puccinelli, P | 1 |
| Caruso, U | 1 |
| Porta, F | 1 |
| Spada, M | 1 |
| Fiumara, A | 1 |
| Barone, R | 1 |
| Nigro, F | 1 |
| Ribes, A | 1 |
| Pavone, L | 1 |
2 other studies available for meglutol and Acute Disease
| Article | Year |
|---|---|
A neonatal case of 3-hydroxy-3-methylglutaric-coenzyme A lyase deficiency.
Topics: Acetyl-CoA C-Acetyltransferase; Acidosis; Acute Disease; Amino Acid Metabolism, Inborn Errors; Gluta | 2013 |
Pancreatitis and organic acidemias.
Topics: Acidosis; Acute Disease; Glutarates; Humans; Infant; Male; Meglutol; Pancreatitis | 1995 |