meglutol has been researched along with Acidosis, Lactic in 2 studies
Meglutol: An antilipemic agent which lowers cholesterol, triglycerides, serum beta-lipoproteins and phospholipids. It acts by interfering with the enzymatic steps involved in the conversion of acetate to hydroxymethylglutaryl coenzyme A as well as inhibiting the activity of HYDROXYMETHYLGLUTARYL COA REDUCTASES which is the rate limiting enzyme in the biosynthesis of cholesterol.
3-hydroxy-3-methylglutaric acid : A dicarboxylic acid that is glutaric acid in which one of the two hydrogens at position 3 is substituted by a hydroxy group, while the other is substituted by a methyl group. It has been found to accumulate in urine of patients suffering from HMG-CoA lyase (3-hydroxy-3-methylglutaryl-CoA lyase, EC 4.1.3.4) deficiency. It occurs as a plant metabolite in Crotalaria dura.
Acidosis, Lactic: Acidosis caused by accumulation of lactic acid more rapidly than it can be metabolized. It may occur spontaneously or in association with diseases such as DIABETES MELLITUS; LEUKEMIA; or LIVER FAILURE.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (50.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ibel, H | 1 |
| Endres, W | 1 |
| Hadorn, HB | 1 |
| Deufel, T | 1 |
| Paetzke, I | 1 |
| Duran, M | 1 |
| Kennaway, NG | 1 |
| Gibson, KM | 1 |
| Haan, EA | 1 |
| Scholem, RD | 1 |
| Pitt, JJ | 1 |
| Wraith, JE | 1 |
| Brown, GK | 1 |
2 other studies available for meglutol and Acidosis, Lactic
| Article | Year |
|---|---|
Multiple respiratory chain abnormalities associated with hypertrophic cardiomyopathy and 3-methylglutaconic aciduria.
Topics: Acidosis, Lactic; Cardiomyopathy, Hypertrophic; Electron Transport Complex IV; Glutarates; Humans; H | 1993 |
Episodes of severe metabolic acidosis in a patient with 3-methylglutaconic aciduria.
Topics: Abnormalities, Multiple; Acidosis; Acidosis, Lactic; Child, Preschool; Citric Acid Cycle; Follow-Up | 1987 |