meglumine-ioxithalamate and Coronary-Disease

In eighty patients with different cardiac diseases the theoretically claimed reduced cardiovascular side effects in ionic and non-ionic low osmolar contrast media compared to those in conventional ionic and high-osmolar contrast media were tested during heart catheterization. The randomized application showed that there were only few reactions during left ventricle angiography and they did not differ between various ejections, while during selective coronary angiography in most cases heart rate and aortic pressures dropped significantly (p less than 0.05). These alterations were significantly (p less than 0.05) stronger in the conventional ionic and high-osmolar ioxitalamat (Telebrix 350) than in the ionic and non-ionic low-osmolar ioxaglat (Hexabrix) or non-ionic low-osmolar iopamidol (Solutrast 370).

Topics: Adult; Aged; Angiography; Cardiomyopathies; Contrast Media; Coronary Angiography; Coronary Disease; Female; Heart Diseases; Heart Valve Diseases; Heart Ventricles; Hemodynamics; Humans; Iodobenzoates; Iothalamate Meglumine; Ioxaglic Acid; Male; Middle Aged; Triiodobenzoic Acids