Page last updated: 2024-08-21

megestrol acetate and Endometrial Hyperplasia

megestrol acetate has been researched along with Endometrial Hyperplasia in 34 studies

Research

Studies (34)

TimeframeStudies, this research(%)All Research%
pre-19904 (11.76)18.7374
1990's1 (2.94)18.2507
2000's6 (17.65)29.6817
2010's13 (38.24)24.3611
2020's10 (29.41)2.80

Authors

AuthorsStudies
Fu, HC; Kung, FT; Lan, J; Lan, KC; Lin, H; Ou, YC; Tsai, YC; Wu, CH1
Liu, Z; Niu, J; Shi, C; Zhao, X1
Chen, X; Guan, J; Liao, J; Luo, X; Ma, F; Ning, C; Shan, W; Shao, W; Wu, P; Xu, Z; Yang, B; Zhang, H; Zhou, S; Zhu, Q1
Chen, XJ; Cheng, YL; Du, Y; Guan, J; Gulinazi, Y; Liu, J; Luo, XZ; Ma, FH; Ning, CC; Shan, WW; Sun, L; Yang, BY; Yu, M; Zhang, HW; Zhu, Q1
Atiomo, W1
Gowri, V; Rawahi, TA; Shikeli, S1
Aghajani, R; Arab, M; Ghahghaei-Nezamabadi, A; Khalagi, K; Sadeghi, S; Tehranian, A1
He, Y; Wang, J; Wang, Y; Zhou, R1
Cho, A; Kim, DY; Kim, JH; Kim, YM; Kim, YT; Lee, SW; Park, JY; Suh, DS1
Catena, U; Fanfani, F; Masciullo, V; Moroni, R; Scambia, G; Trivellizzi, N; Zannoni, G1
Mirmohammadkhanai, M; Moradan, S; Nikkhah, N1
Atiomo, W; Clement, NS; Mulvaney, CA; Oliver, TR; Sanner, JR; Shiwani, H1
Chen, X; Du, Y; Luo, X; Xie, L; Yang, B; Zhang, H; Zhu, Q1
Chen, X; Luo, X; Ning, C; Shan, W; Shi, Y; Xie, B; Xie, L; Xu, Y; Yang, B; Zhang, H; Zhu, Q1
Liu, H; Wang, H; Wang, J; Wang, Y; Zhou, R1
Cao, DY; Cheng, NH; Deng, CY; He, FF; Huang, HF; Shen, K; Sun, ZY; Yang, JX; Yu, M; Yu, Q1
Akdogan, A; Akman, L; Dikmen, Y; Ozsaran, A; Sahin, G; Tavmergen Goker, EN; Tavmergen, E; Terek, MC1
Clarke, BA; Feigenberg, T; Ferguson, SE; Gien, LT; Ismiil, N; Laframboise, S; Massey, C; Simpson, AN1
Kim, MK; Seong, SJ1
Chen, X; Gu, C; Luo, X; Ning, C; Shan, W; Wang, C; Zhang, Z; Zhou, Q1
Bidadi, S; Foroughi, M; Ghojazadeh, M; Melli, MS; Tabrizi, AD1
Bi, Y; Chen, M; Jin, Y; Li, Y; Pan, L; Shan, Y1
Lin, JF; Shen, ZQ; Zhu, HT1
Baiocco, E; Carosi, M; Corrado, G; Vizza, E1
Han, AR; Kim, DY; Kim, JH; Kim, YM; Kim, YT; Kwon, YS; Nam, JH1
Atkins, KA; Hanley, KZ; Mentrikoski, MJ; Shah, AA1
Chen, YM; Lee, CS; Wright, PJ1
Edman, CD; Forney, JP; Gal, D; Vellios, F1
Rose, PG1
Amezcua, CA; Felix, JC; Lu, JJ; Stanczyk, FZ; Zheng, W1
Dikmen, Y; Erhan, Y; Güven, M; Itil, IM; Ozsaran, AA; Terek, MC1
Canetta, R; Kelley, S; Nicaise, C; Rozencweig, M; Schacter, L; Smaldone, L1
Gal, D1
Wentz, WB1

Reviews

2 review(s) available for megestrol acetate and Endometrial Hyperplasia

ArticleYear
Metformin for endometrial hyperplasia.
    The Cochrane database of systematic reviews, 2017, Oct-27, Volume: 10

    Topics: Adult; Aged; Antineoplastic Agents, Hormonal; Disease Progression; Endometrial Hyperplasia; Female; Humans; Hysterectomy; Megestrol Acetate; Metformin; Middle Aged; Precancerous Conditions; Randomized Controlled Trials as Topic; Recurrence; Uterine Hemorrhage; Uterine Neoplasms

2017
Megestrol acetate: clinical experience.
    Cancer treatment reviews, 1989, Volume: 16, Issue:1

    Topics: Acquired Immunodeficiency Syndrome; Adult; Animals; Anorexia; Breast Neoplasms; Cachexia; Carcinoma, Renal Cell; Contraceptive Agents, Male; Contraceptives, Oral; Endometrial Hyperplasia; Female; Humans; Kidney Neoplasms; Male; Megestrol; Megestrol Acetate; Melanoma; Middle Aged; Ovarian Neoplasms; Prostatic Hyperplasia; Prostatic Neoplasms; Rabbits; Tamoxifen; Uterine Neoplasms

1989

Trials

7 trial(s) available for megestrol acetate and Endometrial Hyperplasia

ArticleYear
Levonorgestrel-releasing intrauterine device plus metformin, or megestrol acetate plus metformin for fertility-sparing treatment of atypical endometrial hyperplasia and early endometrial carcinoma: a prospective, randomized, blind-endpoint design trial pr
    Reproductive health, 2022, Nov-04, Volume: 19, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Endometrial Hyperplasia; Endometrial Neoplasms; Female; Humans; Intrauterine Devices, Medicated; Levonorgestrel; Megestrol Acetate; Metformin; Obesity; Pregnancy; Prospective Studies; Randomized Controlled Trials as Topic

2022
Comparison of the effect of levonorgestrel-intrauterine system with or without oral megestrol acetate on fertility-preserving treatment in patients with atypical endometrial hyperplasia: A prospective, open-label, randomized controlled phase II study.
    Gynecologic oncology, 2023, Volume: 174

    Topics: China; Endometrial Hyperplasia; Female; Fertility; Humans; Intrauterine Devices, Medicated; Levonorgestrel; Megestrol Acetate; Pregnancy; Prospective Studies

2023
Metformin plus megestrol acetate compared with megestrol acetate alone as fertility-sparing treatment in patients with atypical endometrial hyperplasia and well-differentiated endometrial cancer: a randomised controlled trial.
    BJOG : an international journal of obstetrics and gynaecology, 2020, Volume: 127, Issue:7

    Topics: Adolescent; Adult; Antineoplastic Agents, Hormonal; China; Drug Therapy, Combination; Endometrial Hyperplasia; Endometrial Neoplasms; Female; Fertility Preservation; Humans; Megestrol Acetate; Metformin; Middle Aged; Treatment Outcome; Young Adult

2020
The impact of adjunctive metformin to progesterone for the treatment of non-atypical endometrial hyperplasia in a randomized fashion, a placebo-controlled, double blind clinical trial.
    Journal of gynecology obstetrics and human reproduction, 2021, Volume: 50, Issue:6

    Topics: Adult; Antineoplastic Agents, Hormonal; Double-Blind Method; Drug Therapy, Combination; Endometrial Hyperplasia; Endometrial Neoplasms; Female; Humans; Megestrol Acetate; Metformin

2021
Comparing the Administration of Letrozole and Megestrol Acetate in the Treatment of Women with Simple Endometrial Hyperplasia without Atypia: A Randomized Clinical Trial.
    Advances in therapy, 2017, Volume: 34, Issue:5

    Topics: Administration, Oral; Adult; Endometrial Hyperplasia; Female; Humans; Letrozole; Megestrol Acetate; Middle Aged; Nitriles; Pilot Projects; Triazoles

2017
Conservative therapy with metformin plus megestrol acetate for endometrial atypical hyperplasia.
    Journal of gynecologic oncology, 2014, Volume: 25, Issue:3

    Topics: Adult; Antineoplastic Agents, Hormonal; Drug Therapy, Combination; Endometrial Hyperplasia; Female; Humans; Hypoglycemic Agents; Megestrol Acetate; Metabolic Syndrome; Metformin; Pilot Projects; Receptors, Estrogen; Receptors, Progesterone; Single-Blind Method; Treatment Outcome

2014
Antiproliferative effect of metformin on the endometrium--a clinical trial.
    Asian Pacific journal of cancer prevention : APJCP, 2014, Volume: 15, Issue:23

    Topics: Adult; Antineoplastic Agents, Hormonal; Atrophy; Carcinoma, Endometrioid; Endometrial Hyperplasia; Endometrial Neoplasms; Endometrium; Female; Humans; Hypoglycemic Agents; Megestrol Acetate; Metformin; Metrorrhagia

2014

Other Studies

25 other study(ies) available for megestrol acetate and Endometrial Hyperplasia

ArticleYear
The role of prolonged progestin treatment and factors predicting successful fertility-sparing treatment for early endometrial endometrioid adenocarcinoma.
    European journal of obstetrics, gynecology, and reproductive biology, 2021, Volume: 267

    Topics: Antineoplastic Agents, Hormonal; Carcinoma, Endometrioid; Endometrial Hyperplasia; Endometrial Neoplasms; Female; Fertility Preservation; Humans; Megestrol Acetate; Pregnancy; Progestins; Retrospective Studies; Treatment Outcome

2021
Is there any move to use metformin for endometrial hyperplasia in routine clinical practice?
    BJOG : an international journal of obstetrics and gynaecology, 2020, Volume: 127, Issue:7

    Topics: Endometrial Hyperplasia; Endometrial Neoplasms; Endometrium; Female; Humans; Hypoglycemic Agents; Megestrol Acetate; Metformin

2020
Fertility-Sparing Treatment in Young Women with Atypical Endometrial Hyperplasia and Low-Grade Endometrial Cancer: A Tertiary Center Experience.
    JBRA assisted reproduction, 2020, 10-06, Volume: 24, Issue:4

    Topics: Adult; Antineoplastic Agents, Hormonal; Endometrial Hyperplasia; Endometrial Neoplasms; Female; Fertility Preservation; Humans; Intrauterine Devices, Medicated; Levonorgestrel; Megestrol Acetate; Treatment Outcome; Young Adult

2020
Oncologic and obstetrical outcomes after fertility-preserving retreatment in patients with recurrent atypical endometrial hyperplasia and endometrial cancer.
    International journal of gynecological cancer : official journal of the International Gynecological Cancer Society, 2020, Volume: 30, Issue:12

    Topics: Adult; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Endometrial Hyperplasia; Endometrial Neoplasms; Female; Fertility Preservation; Gonadotropin-Releasing Hormone; Humans; Levonorgestrel; Medroxyprogesterone Acetate; Megestrol Acetate; Neoplasm Recurrence, Local; Pregnancy; Pregnancy Outcome; Retreatment; Retrospective Studies; Young Adult

2020
Continued medical treatment for persistent early endometrial cancer in young women.
    Gynecologic oncology, 2021, Volume: 160, Issue:2

    Topics: Administration, Oral; Antineoplastic Agents, Hormonal; Biopsy; Carcinoma, Endometrioid; Disease-Free Survival; Drug Administration Schedule; Endometrial Hyperplasia; Endometrial Neoplasms; Endometrium; Female; Fertility Preservation; Follow-Up Studies; Humans; Intrauterine Devices; Levonorgestrel; Magnetic Resonance Imaging; Medroxyprogesterone Acetate; Megestrol Acetate; Myometrium; Neoplasm Grading; Neoplasm Invasiveness; Neoplasm Recurrence, Local; Neoplasm Staging; Neoplasm, Residual; Prognosis; Retrospective Studies; Time Factors; Treatment Failure; Treatment Outcome; Ultrasonography

2021
Prognostic impact of hysteroscopic resection of endometrial atypical hyperplasia-endometrioid intraepithelial neoplasia and early-stage cancer in combination with megestrol acetate.
    American journal of obstetrics and gynecology, 2021, Volume: 224, Issue:4

    Topics: Abortion, Spontaneous; Antineoplastic Agents, Hormonal; Carcinoma, Endometrioid; Combined Modality Therapy; Endometrial Hyperplasia; Endometrial Neoplasms; Female; Fertility Preservation; Fertilization in Vitro; Humans; Hysteroscopy; Live Birth; Megestrol Acetate; Pregnancy; Pregnancy Rate; Prognosis; Prospective Studies

2021
Insulin resistance and overweight prolonged fertility-sparing treatment duration in endometrial atypical hyperplasia patients.
    Journal of gynecologic oncology, 2018, Volume: 29, Issue:3

    Topics: Adult; Body Mass Index; Endometrial Hyperplasia; Female; Fertility Preservation; Humans; Insulin Resistance; Megestrol Acetate; Middle Aged; Overweight; Retrospective Studies; Time Factors; Young Adult

2018
Treatment efficiency of comprehensive hysteroscopic evaluation and lesion resection combined with progestin therapy in young women with endometrial atypical hyperplasia and endometrial cancer.
    Gynecologic oncology, 2019, Volume: 153, Issue:1

    Topics: Administration, Oral; Adult; Endometrial Hyperplasia; Endometrial Neoplasms; Female; Fertility Preservation; Humans; Hysteroscopy; Megestrol Acetate; Metformin; Middle Aged; Progestins; Retrospective Studies; Treatment Outcome; Young Adult

2019
Impact of treatment duration in fertility-preserving management of endometrial cancer or atypical endometrial hyperplasia.
    International journal of gynecological cancer : official journal of the International Gynecological Cancer Society, 2019, Volume: 29, Issue:4

    Topics: Adult; Antineoplastic Agents, Hormonal; Endometrial Hyperplasia; Endometrial Neoplasms; Female; Fertility Preservation; Gonadotropin-Releasing Hormone; Humans; Kaplan-Meier Estimate; Medroxyprogesterone; Megestrol Acetate; Pregnancy; Pregnancy Rate; Retrospective Studies; Treatment Outcome

2019
[Pregnant rate and pregnancy-relating factors of patients with early endometrial carcinoma and severe atypical hyperplasia of endometrium after fertility-preserving treatment by progestin].
    Zhonghua fu chan ke za zhi, 2013, Volume: 48, Issue:7

    Topics: Adult; Antineoplastic Agents, Hormonal; Endometrial Hyperplasia; Endometrial Neoplasms; Endometrium; Female; Fertility Preservation; Humans; Infertility, Female; Medroxyprogesterone; Megestrol Acetate; Pregnancy; Pregnancy Outcome; Pregnancy Rate; Progestins; Reproductive Techniques, Assisted; Retrospective Studies; Treatment Outcome; Young Adult

2013
Reproductive outcomes after progestin therapy in infertile women with endometrial atypical hyperplasia.
    European journal of obstetrics, gynecology, and reproductive biology, 2013, Volume: 171, Issue:2

    Topics: Adult; Endometrial Hyperplasia; Female; Fertilization in Vitro; Humans; Infertility, Female; Megestrol Acetate; Pregnancy; Progestins; Retrospective Studies; Treatment Outcome

2013
Fertility sparing treatment of complex atypical hyperplasia and low grade endometrial cancer using oral progestin.
    Gynecologic oncology, 2014, Volume: 133, Issue:2

    Topics: Adult; Antineoplastic Agents, Hormonal; Carcinoma, Endometrioid; Endometrial Hyperplasia; Endometrial Neoplasms; Female; Fertility Preservation; Humans; Hysterectomy; Medroxyprogesterone Acetate; Megestrol Acetate; Neoplasm Grading; Organ Sparing Treatments; Pregnancy; Pregnancy Outcome; Pregnancy Rate; Reproductive Techniques, Assisted; Retrospective Studies; Treatment Outcome

2014
Conservative treatment for atypical endometrial hyperplasia: what is the most effective therapeutic method?
    Journal of gynecologic oncology, 2014, Volume: 25, Issue:3

    Topics: Antineoplastic Agents, Hormonal; Endometrial Hyperplasia; Female; Humans; Hypoglycemic Agents; Megestrol Acetate; Metformin

2014
Oncologic and reproductive outcomes after fertility-sparing management with oral progestin for women with complex endometrial hyperplasia and endometrial cancer.
    International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 2016, Volume: 132, Issue:1

    Topics: Adult; Antineoplastic Agents, Hormonal; China; Disease-Free Survival; Endometrial Hyperplasia; Endometrial Neoplasms; Female; Fertility; Fertility Preservation; Humans; Medroxyprogesterone Acetate; Megestrol Acetate; Neoplasm Recurrence, Local; Obesity; Pregnancy; Progestins; Recurrence; Retrospective Studies; Treatment Outcome; Young Adult

2016
Reverse of progestin-resistant atypical endometrial hyperplasia by metformin and oral contraceptives.
    Obstetrics and gynecology, 2008, Volume: 112, Issue:2 Pt 2

    Topics: Adult; Contraceptives, Oral, Hormonal; Endometrial Hyperplasia; Female; Humans; Hypoglycemic Agents; Megestrol Acetate; Metformin; Progestins

2008
Progression of conservatively treated endometrial complex atypical hyperplasia in a young woman: a case report.
    Fertility and sterility, 2008, Volume: 90, Issue:5

    Topics: Abortion, Spontaneous; Adult; Antineoplastic Combined Chemotherapy Protocols; Brachytherapy; Carcinoma, Endometrioid; Chemotherapy, Adjuvant; Disease Progression; Endometrial Hyperplasia; Endometrial Neoplasms; Female; Humans; Hysterectomy; Hysteroscopy; Laparoscopy; Megestrol Acetate; Neoplasm Staging; Ovariectomy; Ovulation Induction; Precancerous Conditions; Pregnancy; Radiotherapy, Adjuvant; Treatment Failure

2008
Pregnancy outcomes using assisted reproductive technology after fertility-preserving therapy in patients with endometrial adenocarcinoma or atypical complex hyperplasia.
    International journal of gynecological cancer : official journal of the International Gynecological Cancer Society, 2009, Volume: 19, Issue:1

    Topics: Adenocarcinoma; Adult; Antineoplastic Agents, Hormonal; Dilatation and Curettage; Endometrial Hyperplasia; Endometrial Neoplasms; Female; Humans; Infertility, Female; Medroxyprogesterone Acetate; Megestrol Acetate; Pregnancy; Pregnancy Outcome; Reproductive Techniques, Assisted; Retrospective Studies

2009
Assessing endometrial hyperplasia and carcinoma treated with progestin therapy.
    American journal of clinical pathology, 2012, Volume: 138, Issue:4

    Topics: Adenocarcinoma; Adolescent; Adult; Aged; Antineoplastic Agents, Hormonal; Cohort Studies; Endometrial Hyperplasia; Endometrial Neoplasms; Endometrium; Female; Humans; Levonorgestrel; Megestrol Acetate; Menopause; Middle Aged; Prognosis; Treatment Failure; Young Adult

2012
The roles of progestagen and uterine irritant in the maintenance of cystic endometrial hyperplasia in the canine uterus.
    Theriogenology, 2006, Volume: 66, Issue:6-7

    Topics: Animals; Dog Diseases; Dogs; Endometrial Hyperplasia; Estradiol; Estrous Cycle; Female; Histocytochemistry; Irritants; Megestrol Acetate; Ovariectomy; Progestins; Silk; Sutures

2006
Long-term effect of megestrol acetate in the treatment of endometrial hyperplasia.
    American journal of obstetrics and gynecology, 1983, Jun-01, Volume: 146, Issue:3

    Topics: Adenocarcinoma; Carcinoma in Situ; Endometrial Hyperplasia; Female; Follow-Up Studies; Humans; Megestrol; Megestrol Acetate; Menopause; Middle Aged; Time Factors; Uterine Neoplasms

1983
Hyperglycemia secondary to megestrol acetate for endometrial neoplasia.
    Gynecologic oncology, 1996, Volume: 61, Issue:1

    Topics: Adenocarcinoma; Adenoma; Antineoplastic Agents; Endometrial Hyperplasia; Endometrial Neoplasms; Female; Humans; Hyperglycemia; Insulin; Megestrol; Megestrol Acetate; Middle Aged

1996
Apoptosis may be an early event of progestin therapy for endometrial hyperplasia.
    Gynecologic oncology, 2000, Volume: 79, Issue:2

    Topics: Adult; Apoptosis; Cell Count; Endometrial Hyperplasia; Endometrium; Female; Humans; In Situ Nick-End Labeling; Medroxyprogesterone Acetate; Megestrol Acetate; Middle Aged; Paraffin Embedding; Progesterone Congeners; Progestins; Tumor Cells, Cultured

2000
Metabolic effects associated with high-dose continuous megestrol acetate administration in the treatment of endometrial pathology.
    Archives of gynecology and obstetrics, 2001, Volume: 265, Issue:4

    Topics: Adult; Apolipoprotein A-I; Apolipoproteins B; Blood Glucose; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Endometrial Hyperplasia; Fasting; Female; Food; Humans; Lipids; Megestrol Acetate; Middle Aged; Postmenopause; Triglycerides; Uterine Hemorrhage; Weight Gain

2001
Hormonal therapy for lesions of the endometrium.
    Seminars in oncology, 1986, Volume: 13, Issue:4 Suppl 4

    Topics: Body Weight; Endometrial Hyperplasia; Female; Follow-Up Studies; Humans; Megestrol; Megestrol Acetate; Recurrence

1986
Progestin therapy in lesions of the endometrium.
    Seminars in oncology, 1985, Volume: 12, Issue:1 Suppl 1

    Topics: Adenocarcinoma; Adult; Endometrial Hyperplasia; Female; Humans; Megestrol; Megestrol Acetate; Middle Aged; Neoplasm Recurrence, Local; Uterine Neoplasms

1985