mefloquine hydrochloride has been researched along with Leukoencephalopathy, Progressive Multifocal in 1 studies
[2,8-bis(trifluoromethyl)quinolin-4-yl]-(2-piperidyl)methanol : An organofluorine compound that consists of quinoline bearing trifluoromethyl substituents at positions 2 and 8 as well as a (2-piperidinyl)hydroxymethyl substituent at position 4.
Leukoencephalopathy, Progressive Multifocal: An opportunistic viral infection of the central nervous system associated with conditions that impair cell-mediated immunity (e.g., ACQUIRED IMMUNODEFICIENCY SYNDROME and other IMMUNOLOGIC DEFICIENCY SYNDROMES; HEMATOLOGIC NEOPLASMS; IMMUNOSUPPRESSION; and COLLAGEN DISEASES). The causative organism is JC Polyomavirus (JC VIRUS) which primarily affects oligodendrocytes, resulting in multiple areas of demyelination. Clinical manifestations include DEMENTIA; ATAXIA; visual disturbances; and other focal neurologic deficits, generally progressing to a vegetative state within 6 months. (From Joynt, Clinical Neurology, 1996, Ch26, pp36-7)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Brickelmaier, M | 1 |
| Lugovskoy, A | 1 |
| Kartikeyan, R | 1 |
| Reviriego-Mendoza, MM | 1 |
| Allaire, N | 1 |
| Simon, K | 1 |
| Frisque, RJ | 1 |
| Gorelik, L | 1 |
1 other study available for mefloquine hydrochloride and Leukoencephalopathy, Progressive Multifocal
| Article | Year |
|---|---|
Identification and characterization of mefloquine efficacy against JC virus in vitro.
Topics: Antiviral Agents; Astrocytes; Cell Line, Transformed; Cells, Cultured; Humans; JC Virus; Leukoenceph | 2009 |