Page last updated: 2024-08-23

mefloquine and Disease Models, Animal

mefloquine has been researched along with Disease Models, Animal in 55 studies

Research

Studies (55)

Timeframe	Studies, this research(%)	All Research%
pre-1990	2 (3.64)	18.7374
1990's	3 (5.45)	18.2507
2000's	13 (23.64)	29.6817
2010's	31 (56.36)	24.3611
2020's	6 (10.91)	2.80

Authors

Authors	Studies
Bacher, A; Behrendt, C; Brücher, K; Fischer, M; Gräwert, T; Held, J; Illarionov, B; Konzuch, S; Kurz, T; Lienau, C; Maes, L; Mordmüller, B; Wittlin, S	1
Brantner, A; Brun, R; Bucar, F; Faist, J; Gröblacher, B; Kaiser, M; Kalia, Y; Merino, V; Perozzo, R; Saf, R; Scapozza, L; Seebacher, W; Weis, R; Wolkinger, V	1
Angulo-Barturen, I; Antonova-Koch, Y; Bashyam, S; Birkholtz, LM; Botha, ME; Charman, SA; Chibale, K; Ferrer, S; Gonzàlez Cabrera, D; Han, Z; Jiménez-Díaz, MB; Lawrence, N; Le Manach, C; Martínez, MS; Meister, S; Nchinda, AT; Nondaba, SH; Paquet, T; Reader, J; Street, LJ; Taylor, D; Waterson, D; White, KL; Winzeler, EA; Wittlin, S; Witty, MJ; Younis, Y; Zabiulla, M	1
Bane, CE; Black, C; Butler, K; Caridha, D; Cooper, RA; Dodean, RA; Gaona, H; Gaynor-Ohnstad, L; Huezo, SJ; Kancharla, P; Kelly, JX; Kreishman-Deitrick, M; Leed, SE; Li, Q; Li, Y; Lin, H; Luong, TL; Marcsisin, S; Melendez, V; Nolan, C; Olmeda, R; Potter, B; Pou, S; Rasmussen, SA; Read, L; Riscoe, MK; Roncal, N; Sciotti, RJ; Smilkstein, MJ; Sousa, J; Stephens, MT; Tan, JC; Vesely, B; Vuong, C; Winter, RW; Xie, L; Zeng, Q; Zhang, J; Zhang, P	1
Carlier, PR; Ding, S; Fike, KR; Klemba, M	1
Boroujeni, SS; Dehpour, AR; Jafari, RM; Karimi, E; Maleki, A; Mohammadi, P; Sabzevari, O; Shafaroodi, H; Solaimanian, S	1
Santhakumar, V; Shao, M; Yu, H; Yu, J	1
Bhatia, SN; Grilo Ruivo, MT; Lemos Rocha, LF; Mancio-Silva, L; Marques, S; Mota, MM; Vera, IM	1
Hemphill, A; Lundström-Stadelmann, B; Rufener, R	1
Carvalho, LJM; Nugraha, AB; Sivakumar, T; Tuvshintulga, B; Yokoyama, N	1
Amer, BS; El-Ebiary, AA; Elkaliny, HH; Elmehy, DA; Gamea, GA; Ismail, HIH; Soliman, NA	1
Chen, Z; Shen, X; Wu, H; Zhang, M	1
Gong, LL; Li, YH; Lin, RX; Wu, JC; Yang, SL; Zhang, GF	1
Blauwblomme, T; Capelle, L; Chever, O; Couillin, I; Dossi, E; Guinard, E; Huberfeld, G; Le Bert, M; Moulard, J; Pallud, J; Rouach, N; Vasile, F	1
Akter, J; Aogo, RA; Cromer, D; Davenport, MP; Elliott, T; Fogg, LG; Haque, A; Khoury, DS; Laohamonthonkul, P; Liligeto, UN; Nair, AS; Pernold, CPS; Romanczuk, AS; Soon, MSF; Thomas, BS	1
Amnuaysirikul, J; Caridha, D; Gao, X; Grogl, M; Hickman, M; Ishida, H; Li, Q; Magill, AJ; O'Neil, MT; Ohrt, C; Ray, P; Weina, PJ; Zhang, P	1
Ballesteros-Zebadúa, P; Franco-Pérez, J; Manjarrez-Marmolejo, J	1
Hemphill, A; Küster, T; Müller, J; Risch, C; Rufener, R; Stadelmann, B	1
Cahill, ME; Christoffel, DJ; Golden, SA; Heshmati, M; Khibnik, LA; Pfau, ML; Russo, SJ; Seeley, EL	1
Chen, ZY; Jiang, L; Liu, S; Shen, FY; Shen, XL; Wang, YW; Wang, ZR; Zhao, X; Zhong, W	1
Kamel, RO	1
Angulo-Barturen, I; Baker, M; Duparc, S; Elliott, S; Ferrer, S; Griffin, P; Hooft van Huijsduijnen, R; Jiménez-Díaz, MB; Leroy, D; Marquart, L; Martínez, MS; McCarthy, JS; Möhrle, JJ; O'Rourke, P; Rockett, R; Sekuloski, S; Sloots, T; Trenholme, K; Wells, TN	1
Cabral, L; Cristiano, ML; Lobo, L; Nogueira, F; Sousa, Bd	1
Abbadi, BL; Basso, LA; Campos, MM; de Souza, MV; Gonçalves, RS; González-Martín, J; López-Gavín, A; Rodrigues-Junior, VS; Santos, DS; Trindade, RV; Tudó, G; Villela, AD	1
Gorgas, D; Hemphill, A; Lundström-Stadelmann, B; Marreros, N; Rufener, R	1
Jiao, PY; Mei, JY; Xiao, SH	2
Xiao, SH; Zhang, CW	2
Li-li, X; Qiang, HQ; Xiao, SH; Xue, J; Zhang, YN	1
Hemphill, A; Hermann, C; Keiser, J; Küster, T; Scholl, S; Stadelmann, B	1
Keiser, J; Manneck, T; Vargas, M	1
Du, XL; Sun, J; Xiao, SH; Xue, J; Zhang, HB	1
Cozens, S; Dow, GS; Gettayacamin, M; Hansukjariya, P; Imerbsin, R; Kenworthy, D; Komcharoen, S; Kyle, D; Milhous, W; Miller, A; Ohrt, C; Sattabongkot, J; Veazey, J	1
Bentura-Marciano, A; Chan, WC; Clark, J; Golenser, J; Guiguemde, AW; Guo, J; Guy, RK; Haynes, RK; Hunt, NH; Wong, HN	1
el-Din, SH; el-Lakkany, NM; Hammam, OA; Sabra, AN	1
Sun, J; Xiao, SH; Xue, J	1
Amalvict, R; Baret, E; Briolant, S; Dormoi, J; Mosnier, J; Pradines, B; Rogier, C; Savini, H; Soulard, R; Souraud, JB	1
Agrawal, R; Dutta, GP; Jain, SK; Shukla, OP; Tekwani, BL; Tripathi, R	1
Bermudez, LE; Inderlied, CB; Kolonoski, P; Petrofsky, M; Wu, M; Young, LS	1
Peters, W; Robinson, BL; Stewart, LB	1
Benwell, K; Cliffe, IA; Dourish, CT; Gillespie, RJ; Knight, AR; Lerpiniere, J; Misra, A; Pratt, RM; Revell, D; Upton, R; Weiss, SM	1
Amabeoku, GJ; Farmer, CC	1
Carmona-Fonseca, J; Guzmán, V	1
Handforth, A; Martin, FC	1
Barnwell, JW; Bounngaseng, A; Collins, WE; Galland, GG; Grady, KK; Hall, P; Huber, C; Nace, D; Ruebush, TK; Sullivan, JJ; Sullivan, JS; Williams, A; Williams, T	1
Gozalo, AS; Hall, BT; Lucas, CM; Magill, AJ; Qin, J	1
Peters, W	1
Ager, AL; Canfield, CJ; Heiffer, MH; Klayman, DL; Kyle, DE; Milhous, WK; Rossan, RN; Schuster, BG; Shmuklarsky, MJ; Tang, DB	1
Collins, WE; Galland, GG; Kaslow, DC; Lal, AA; Morris, CL; Saekhou, AM; Sullivan, JS; Xiao, L; Yang, C	1
Collins, WE; Fryauff, DJ; Galland, GG; Jennings, V; Kendall, J; Morris, CL; Sullivan, JS	1
Bermudez, LE; Young, LS	1
Cravo, P; Culleton, R; Hunt, P; Mackinnon, MJ; Walliker, D	1
Onabanjo, AO; Otigbuo, IN	1
Armstead, A; Campbell, CC; Collins, WE; Milhous, WK; Roberts, JM	1

Reviews

3 review(s) available for mefloquine and Disease Models, Animal

Article	Year
[Cytochrome P-450 and the response to antimalarial drugs]. Revista panamericana de salud publica = Pan American journal of public health, 2006, Volume: 19, Issue:1 Topics: Administration, Oral; Adult; Amodiaquine; Animals; Antimalarials; Biotransformation; Child; Chloroquine; Cytochrome P-450 Enzyme System; Databases as Topic; Disease Models, Animal; Genotype; Humans; Malaria; Malaria, Falciparum; Mefloquine; Mice; Murinae; Mutation; Nutritional Status; Phenotype; Plasmodium berghei; Polymorphism, Genetic; Proguanil; Rats	2006
New answers through chemotherapy? Experientia, 1984, Dec-15, Volume: 40, Issue:12 Topics: Aminoquinolines; Animals; Antimalarials; Chemical Phenomena; Chemistry; Disease Models, Animal; Drug Resistance; Drug Therapy, Combination; Erythrocytes; Humans; Liver; Malaria; Mefloquine; Plasmodium; Plasmodium falciparum; Plasmodium malariae; Plasmodium vivax; Primaquine; Proguanil; Quinine; Quinolines; Research; Sesquiterpenes; Species Specificity; World Health Organization	1984
Perspective on animal models: chronic intracellular infections. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2001, Sep-15, Volume: 33 Suppl 3 Topics: Animals; Antitubercular Agents; Chronic Disease; Disease Models, Animal; Humans; Mefloquine; Mice; Mice, Inbred C57BL; Mycobacterium avium Complex; Mycobacterium avium-intracellulare Infection; Predictive Value of Tests	2001

Trials

1 trial(s) available for mefloquine and Disease Models, Animal

Article	Year
Linking Murine and Human Plasmodium falciparum Challenge Models in a Translational Path for Antimalarial Drug Development. Antimicrobial agents and chemotherapy, 2016, Volume: 60, Issue:6 Topics: Adult; Animals; Antimalarials; Cohort Studies; Disease Models, Animal; Drug Administration Schedule; Drug Dosage Calculations; Erythrocytes; Female; Healthy Volunteers; Humans; Inhibitory Concentration 50; Malaria, Falciparum; Male; Mefloquine; Mice; Mice, Inbred NOD; Mice, Knockout; Mice, SCID; Plasmodium falciparum	2016

Article

Year

Linking Murine and Human Plasmodium falciparum Challenge Models in a Translational Path for Antimalarial Drug Development.

Antimicrobial agents and chemotherapy, 2016, Volume: 60, Issue:6

Topics: Adult; Animals; Antimalarials; Cohort Studies; Disease Models, Animal; Drug Administration Schedule; Drug Dosage Calculations; Erythrocytes; Female; Healthy Volunteers; Humans; Inhibitory Concentration 50; Malaria, Falciparum; Male; Mefloquine; Mice; Mice, Inbred NOD; Mice, Knockout; Mice, SCID; Plasmodium falciparum

2016

Other Studies

51 other study(ies) available for mefloquine and Disease Models, Animal

Article	Year
Prodrugs of reverse fosmidomycin analogues. Journal of medicinal chemistry, 2015, Feb-26, Volume: 58, Issue:4 Topics: Animals; Antimalarials; Cell Survival; Disease Models, Animal; Dose-Response Relationship, Drug; Fosfomycin; HeLa Cells; Humans; Malaria; Mice; Mice, SCID; Molecular Structure; Plasmodium berghei; Plasmodium falciparum; Prodrugs; Structure-Activity Relationship	2015
Synthesis of 3-azabicyclo[3.2.2]nonanes and their antiprotozoal activities. Bioorganic & medicinal chemistry letters, 2015, Apr-01, Volume: 25, Issue:7 Topics: Administration, Oral; Animals; Antiprotozoal Agents; Azabicyclo Compounds; Disease Models, Animal; Dose-Response Relationship, Drug; Injections, Intravenous; Male; Mice; Molecular Structure; Parasitic Sensitivity Tests; Plasmodium berghei; Plasmodium falciparum; Rats; Structure-Activity Relationship; Tissue Distribution; Trypanosoma brucei rhodesiense; Trypanosomiasis, African	2015
Identification of a Potential Antimalarial Drug Candidate from a Series of 2-Aminopyrazines by Optimization of Aqueous Solubility and Potency across the Parasite Life Cycle. Journal of medicinal chemistry, 2016, 11-10, Volume: 59, Issue:21 Topics: Animals; Antimalarials; Disease Models, Animal; Dose-Response Relationship, Drug; Ether-A-Go-Go Potassium Channels; Hep G2 Cells; Humans; Life Cycle Stages; Malaria; Mice; Mice, SCID; Microsomes, Liver; Molecular Structure; Parasitic Diseases, Animal; Parasitic Sensitivity Tests; Plasmodium berghei; Plasmodium falciparum; Pyrazines; Solubility; Structure-Activity Relationship; Water	2016
Discovery and Structural Optimization of Acridones as Broad-Spectrum Antimalarials. Journal of medicinal chemistry, 2019, 04-11, Volume: 62, Issue:7 Topics: Acridones; Animals; Antimalarials; Disease Models, Animal; Drug Discovery; Hep G2 Cells; Humans; Malaria; Mice; Plasmodium; Species Specificity; Structure-Activity Relationship	2019
In vitro and in vivo evaluation of the antimalarial MMV665831 and structural analogs. Bioorganic & medicinal chemistry letters, 2020, 09-01, Volume: 30, Issue:17 Topics: Animals; Antimalarials; Disease Models, Animal; Malaria; Mannich Bases; Mice; Plasmodium berghei; Plasmodium falciparum	2020
Opioidergic and nitrergic systems mediate the anticonvulsant effect of mefloquine and chloroquine on seizures induced by pentylenetetrazol and maximal electroshock in mice. Acta neurobiologiae experimentalis, 2022, Volume: 82, Issue:2 Topics: Animals; Anticonvulsants; Chloroquine; Disease Models, Animal; Electroshock; Mefloquine; Mice; Naltrexone; Nitrites; Pentylenetetrazole; Seizures	2022
Antiepileptogenic and neuroprotective effect of mefloquine after experimental status epilepticus. Epilepsy research, 2023, Volume: 198 Topics: Animals; Disease Models, Animal; Epilepsy; Epilepsy, Temporal Lobe; Hippocampus; Mefloquine; Neuroprotective Agents; Pilocarpine; Rats; Seizures; Status Epilepticus	2023
Targeting liver stage malaria with metformin. JCI insight, 2019, 12-19, Volume: 4, Issue:24 Topics: Animals; Antimalarials; Cells, Cultured; Disease Models, Animal; Drug Evaluation, Preclinical; Drug Repositioning; Drug Therapy, Combination; Hepatocytes; Humans; Inhibitory Concentration 50; Liver; Malaria; Male; Mefloquine; Metformin; Mice; Parasite Load; Parasitic Sensitivity Tests; Plasmodium berghei; Plasmodium falciparum; Primaquine; Primary Cell Culture	2019
Drug repurposing applied: Activity of the anti-malarial mefloquine against Echinococcus multilocularis. International journal for parasitology. Drugs and drug resistance, 2020, Volume: 13 Topics: Albendazole; Animals; Anticestodal Agents; Antimalarials; Disease Models, Animal; Drug Evaluation, Preclinical; Drug Repositioning; Echinococcosis; Echinococcus multilocularis; Ferritins; Humans; Mefloquine; Mice	2020
Activities of artesunate-based combinations and tafenoquine against Babesia bovis in vitro and Babesia microti in vivo. Parasites & vectors, 2020, Jul-20, Volume: 13, Issue:1 Topics: Aminoquinolines; Animals; Antimalarials; Artesunate; Babesia bovis; Babesia microti; Babesiosis; Disease Models, Animal; Drug Combinations; In Vitro Techniques; Lumefantrine; Mefloquine; Methylene Blue; Mice; Mice, Inbred BALB C	2020
Oxidative stress mediated apoptotic potential of mefloquine on experimental trichinellosis. Acta tropica, 2021, Volume: 213 Topics: Albendazole; Animals; Anthelmintics; Apoptosis; Disease Models, Animal; Jejunum; Larva; Male; Mefloquine; Mice; Muscles; Oxidative Stress; Reactive Oxygen Species; Trichinella spiralis; Trichinellosis	2021
Membrane potential synchrony of neurons in anterior cingulate cortex plays a pivotal role in generation of neuropathic pain. Scientific reports, 2018, 01-26, Volume: 8, Issue:1 Topics: Action Potentials; Analgesics; Animals; Chronic Disease; Constriction, Pathologic; Disease Models, Animal; Gyrus Cinguli; Mefloquine; Membrane Potentials; Neuralgia; Neurons; Rats, Sprague-Dawley	2018
Mefloquine targets β-catenin pathway and thus can play a role in the treatment of liver cancer. Microbial pathogenesis, 2018, Volume: 118 Topics: AC133 Antigen; Animals; beta Catenin; Carcinoma, Hepatocellular; Cell Proliferation; Cell Survival; Cyclin D1; Disease Models, Animal; Drug Combinations; Hep G2 Cells; Humans; Lithium Chloride; Liver Neoplasms; Male; Mefloquine; Mice; Mice, Inbred BALB C; Neoplastic Stem Cells; Transplantation, Heterologous	2018
Pannexin-1 channels contribute to seizure generation in human epileptic brain tissue and in a mouse model of epilepsy. Science translational medicine, 2018, 05-30, Volume: 10, Issue:443 Topics: Adenosine Triphosphate; Animals; Brain; Cerebral Cortex; Connexins; Disease Models, Animal; Epilepsy; Epilepsy, Temporal Lobe; Humans; Kainic Acid; Mefloquine; Mice; Nerve Tissue Proteins; Probenecid; Seizures; Signal Transduction	2018
Quantification of host-mediated parasite clearance during blood-stage Plasmodium infection and anti-malarial drug treatment in mice. International journal for parasitology, 2018, Volume: 48, Issue:12 Topics: Animals; Antimalarials; Artesunate; Blood; Disease Models, Animal; Fluorescence; Malaria; Mefloquine; Mice; Models, Theoretical; Organisms, Genetically Modified; Parasite Load; Parasitemia; Plasmodium berghei; Staining and Labeling	2018
An in vivo drug screening model using glucose-6-phosphate dehydrogenase deficient mice to predict the hemolytic toxicity of 8-aminoquinolines. The American journal of tropical medicine and hygiene, 2013, Volume: 88, Issue:6 Topics: Acute Disease; Aminoquinolines; Anemia, Hemolytic; Animals; Antimalarials; Chloroquine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Genotype; Glucosephosphate Dehydrogenase Deficiency; Glutathione; Haptoglobins; Hemolytic Agents; Male; Mefloquine; Mice; Phenotype; Primaquine; Reticulocyte Count	2013
Anticonvulsant effects of mefloquine on generalized tonic-clonic seizures induced by two acute models in rats. BMC neuroscience, 2015, Mar-01, Volume: 16 Topics: Acute Disease; Animals; Anticonvulsants; Brain; Disease Models, Animal; Dose-Response Relationship, Drug; Electrodes, Implanted; Electroencephalography; Electroshock; Hindlimb; Male; Mefloquine; Pentylenetetrazole; Random Allocation; Rats; Rats, Wistar; Seizures; Survival Analysis	2015
Oral treatments of Echinococcus multilocularis-infected mice with the antimalarial drug mefloquine that potentially interacts with parasite ferritin and cystatin. International journal of antimicrobial agents, 2015, Volume: 46, Issue:5 Topics: Administration, Oral; Animals; Anthelmintics; Antimalarials; Caco-2 Cells; Chromatography, Affinity; Chromatography, Liquid; Cystatins; Disease Models, Animal; Drug Repositioning; Echinococcosis; Echinococcus multilocularis; Electrophoresis, Polyacrylamide Gel; Female; Ferritins; Humans; Mefloquine; Mice, Inbred BALB C; Protein Binding; Tandem Mass Spectrometry; Treatment Outcome	2015
Mefloquine in the nucleus accumbens promotes social avoidance and anxiety-like behavior in mice. Neuropharmacology, 2016, Volume: 101 Topics: Action Potentials; Analysis of Variance; Animals; Anxiety; Disease Models, Animal; Dose-Response Relationship, Drug; Interpersonal Relations; Male; Maze Learning; Mefloquine; Mice; Mice, Inbred C57BL; Neurons; Nucleus Accumbens; Patch-Clamp Techniques; Stress, Psychological	2016
Attenuation of Neuropathic Pain by Inhibiting Electrical Synapses in the Anterior Cingulate Cortex. Anesthesiology, 2016, Volume: 124, Issue:1 Topics: Animals; Connexins; Disease Models, Animal; Electrical Synapses; Gap Junction delta-2 Protein; Gyrus Cinguli; Mefloquine; Neuralgia; Neuronal Plasticity; Neurons; Rats; Synaptic Transmission	2016
Interactions between mefloquine and the anti-fibrotic drug silymarin on Schistosoma mansoni infections in mice. Journal of helminthology, 2016, Volume: 90, Issue:6 Topics: Animals; Anthelmintics; Antibodies, Helminth; Disease Models, Animal; Drug Interactions; Enzymes; Fibrosis; Granuloma; Inflammation; Liver Function Tests; Male; Mefloquine; Mice; Parasite Load; Schistosomiasis mansoni; Silymarin; Treatment Outcome	2016
Highly active ozonides selected against drug resistant malaria. Memorias do Instituto Oswaldo Cruz, 2016, Jun-07, Volume: 0 Topics: Animals; Antimalarials; Artemisinins; Artesunate; Chloroquine; Disease Models, Animal; Female; Humans; Malaria, Falciparum; Mefloquine; Mice; Parasitemia; Plasmodium falciparum	2016
Mefloquine and its oxazolidine derivative compound are active against drug-resistant Mycobacterium tuberculosis strains and in a murine model of tuberculosis infection. International journal of antimicrobial agents, 2016, Volume: 48, Issue:2 Topics: Animals; Antitubercular Agents; Bacterial Load; Disease Models, Animal; Drug Interactions; Drug Repositioning; Male; Mefloquine; Mice; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Oxazoles; Tuberculosis, Multidrug-Resistant	2016
To see or not to see: non-invasive imaging for improved readout of drug treatment trials in the murine model of secondary alveolar echinococcosis. Parasitology, 2017, Volume: 144, Issue:7 Topics: Albendazole; Animals; Anticestodal Agents; Disease Models, Animal; Echinococcosis; Echinococcus multilocularis; Female; Magnetic Resonance Imaging; Mefloquine; Mice; Mice, Inbred BALB C; Parasite Load; Ultrasonography	2017
Further study on mefloquine concerning several aspects in experimental treatment of mice and hamsters infected with Schistosoma japonicum. Parasitology research, 2009, Volume: 106, Issue:1 Topics: Administration, Oral; Animals; Anthelmintics; Cricetinae; Disease Models, Animal; Female; Hepatic Veins; Male; Mefloquine; Mesenteric Veins; Mice; Praziquantel; Schistosoma japonicum; Schistosomiasis japonica; Treatment Outcome	2009
Further observation on histopathological alterations of adult Schistosoma japonicum harbored in mice following treatment with mefloquine at a smaller single dose. Parasitology research, 2010, Volume: 107, Issue:4 Topics: Administration, Oral; Animal Structures; Animals; Anthelmintics; Disease Models, Animal; Female; Histocytochemistry; Liver; Male; Mefloquine; Mice; Schistosoma japonicum; Schistosomiasis japonica; Time Factors	2010
Effectiveness of mefloquine against Clonorchis sinensis in rats and Paragonimus westermani in dogs. Parasitology research, 2010, Volume: 107, Issue:6 Topics: Animals; Anthelmintics; Clonorchiasis; Clonorchis sinensis; Disease Models, Animal; Dog Diseases; Dogs; Mefloquine; Paragonimiasis; Paragonimus westermani; Rats; Rodent Diseases; Survival Analysis; Treatment Outcome	2010
Effect of mefloquine administered orally at single, multiple, or combined with artemether, artesunate, or praziquantel in treatment of mice infected with Schistosoma japonicum. Parasitology research, 2011, Volume: 108, Issue:2 Topics: Administration, Oral; Animals; Artemether; Artemisinins; Artesunate; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Female; Mefloquine; Mice; Mice, Inbred Strains; Parasitic Diseases, Animal; Parasitic Sensitivity Tests; Praziquantel; Schistosoma japonicum; Schistosomiasis japonica; Schistosomicides; Treatment Outcome	2011
In vitro and in vivo efficacies of mefloquine-based treatment against alveolar echinococcosis. Antimicrobial agents and chemotherapy, 2011, Volume: 55, Issue:2 Topics: Albendazole; Animals; Antiparasitic Agents; Disease Models, Animal; Echinococcosis; Echinococcosis, Hepatic; Echinococcus multilocularis; Female; Humans; Mefloquine; Mice; Mice, Inbred BALB C; Microscopy, Electron, Scanning; Parasitic Sensitivity Tests; Treatment Outcome	2011
Interactions of mefloquine with praziquantel in the Schistosoma mansoni mouse model and in vitro. The Journal of antimicrobial chemotherapy, 2011, Volume: 66, Issue:8 Topics: Administration, Oral; Animals; Anthelmintics; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Female; Mefloquine; Mice; Praziquantel; Rodent Diseases; Schistosoma mansoni; Schistosomiasis mansoni; Treatment Outcome	2011
Ultrastructural alterations of juvenile Schistosoma japonicum harbored in mice following mefloquine administration. Parasitology research, 2012, Volume: 110, Issue:2 Topics: Administration, Oral; Animal Structures; Animals; Anthelmintics; Disease Models, Animal; Female; Mefloquine; Mice; Microscopy, Electron, Transmission; Organelles; Schistosoma japonicum; Schistosomiasis japonica	2012
Radical curative efficacy of tafenoquine combination regimens in Plasmodium cynomolgi-infected Rhesus monkeys (Macaca mulatta). Malaria journal, 2011, Jul-29, Volume: 10 Topics: Aminoquinolines; Animals; Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Chloroquine; Chromatography, Liquid; Disease Models, Animal; Drug Combinations; Drug Therapy, Combination; Ethanolamines; Fluorenes; Humans; Macaca mulatta; Malaria; Male; Mass Spectrometry; Mefloquine; Plasma; Plasmodium cynomolgi; Primate Diseases; Quinine; Treatment Outcome	2011
Synthesis of artemiside and its effects in combination with conventional drugs against severe murine malaria. Antimicrobial agents and chemotherapy, 2012, Volume: 56, Issue:1 Topics: Animals; Antimalarials; Artemisinins; Disease Models, Animal; Drug Administration Schedule; Drug Synergism; Drug Therapy, Combination; High-Throughput Screening Assays; Humans; Inhibitory Concentration 50; Malaria, Cerebral; Malaria, Falciparum; Mefloquine; Mice; Mice, Inbred C57BL; Microscopy; Parasitemia; Plasmodium berghei; Plasmodium falciparum; Quinolines; Secondary Prevention; Survival Rate	2012
Pharmacodynamics of mefloquine and praziquantel combination therapy in mice harbouring juvenile and adult Schistosoma mansoni. Memorias do Instituto Oswaldo Cruz, 2011, Volume: 106, Issue:7 Topics: Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Granuloma; Liver; Male; Mefloquine; Mice; Parasite Egg Count; Praziquantel; Schistosoma mansoni; Schistosomiasis mansoni; Schistosomicides	2011
Histopathological changes of juvenile Schistosoma japonicum harbored in mice treated orally with mefloquine at a smaller single dose. Parasitology research, 2012, Volume: 110, Issue:6 Topics: Animal Structures; Animals; Anthelmintics; Disease Models, Animal; Female; Liver; Mefloquine; Mice; Microscopy; Schistosoma japonicum; Schistosomiasis japonica; Survival Analysis; Time Factors	2012
Confocal laser scanning microscopic observation on adult Schistosoma japonicum harbored in mice following treatment with single-dose mefloquine. Parasitology research, 2012, Volume: 110, Issue:6 Topics: Administration, Oral; Animal Structures; Animals; Anthelmintics; Disease Models, Animal; Female; Liver; Male; Mefloquine; Mesenteric Veins; Mice; Microscopy, Confocal; Schistosoma japonicum; Schistosomiasis japonica	2012
Atorvastatin treatment is effective when used in combination with mefloquine in an experimental cerebral malaria murine model. Malaria journal, 2012, Jan-10, Volume: 11 Topics: Animals; Antimalarials; Apoptosis; Atorvastatin; Brain; Disease Models, Animal; Drug Therapy, Combination; Female; Heptanoic Acids; Histocytochemistry; Immunohistochemistry; Malaria, Cerebral; Mefloquine; Mice; Neurons; Plasmodium berghei; Pyrroles; Survival Analysis; Treatment Outcome	2012
Haem polymerase as a novel target of antimalarial action of cyproheptadine. Biochemical pharmacology, 2002, Nov-01, Volume: 64, Issue:9 Topics: Animals; Antimalarials; Chloroquine; Cyproheptadine; Disease Models, Animal; Drug Resistance; Enzyme Inhibitors; Hemeproteins; Mefloquine; Mice; Plasmodium yoelii; Quinine; Transferases; Treatment Outcome	2002
Mefloquine, moxifloxacin, and ethambutol are a triple-drug alternative to macrolide-containing regimens for treatment of Mycobacterium avium disease. The Journal of infectious diseases, 2003, Jun-15, Volume: 187, Issue:12 Topics: Animals; Anti-Bacterial Agents; Anti-Infective Agents; Antimalarials; Aza Compounds; Clarithromycin; Disease Models, Animal; Drug Resistance, Bacterial; Drug Therapy, Combination; Ethambutol; Fluoroquinolones; Mefloquine; Mice; Moxifloxacin; Mycobacterium avium Complex; Mycobacterium avium-intracellulare Infection; Quinolines	2003
The chemotherapy of rodent malaria. LXI. Drug combinations to impede the selection of drug resistance, part 4: the potential role of 8-aminoquinolines. Annals of tropical medicine and parasitology, 2003, Volume: 97, Issue:3 Topics: Aminoquinolines; Animals; Antimalarials; Chloroquine; Disease Models, Animal; Drug Resistance; Drug Therapy, Combination; Malaria; Malaria, Falciparum; Malaria, Vivax; Mefloquine; Mice; Plasmodium berghei; Plasmodium chabaudi; Plasmodium yoelii; Primaquine; Time Factors	2003
Discovery of nonxanthine adenosine A2A receptor antagonists for the treatment of Parkinson's disease. Neurology, 2003, Dec-09, Volume: 61, Issue:11 Suppl 6 Topics: Adenosine; Adenosine A2 Receptor Antagonists; Animals; Antiparkinson Agents; Binding, Competitive; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Design; Drug Evaluation, Preclinical; Humans; Ligands; Mefloquine; Mice; Motor Activity; Neuroprotective Agents; Parkinsonian Disorders; Phenethylamines; Purines; Pyrimidines; Radioligand Assay; Rats; Triazines; Triazoles	2003
Gamma-aminobutyric acid and mefloquine-induced seizures in mice. Progress in neuro-psychopharmacology & biological psychiatry, 2005, Volume: 29, Issue:6 Topics: Acetanilides; Aminooxyacetic Acid; Animals; Anti-Anxiety Agents; Chi-Square Distribution; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Male; Mefloquine; Mice; Seizures	2005
Carbenoxolone and mefloquine suppress tremor in the harmaline mouse model of essential tremor. Movement disorders : official journal of the Movement Disorder Society, 2006, Volume: 21, Issue:10 Topics: 1-Octanol; Animals; Carbenoxolone; Central Nervous System Stimulants; Cerebellum; Chloroquine; Connexins; Disease Models, Animal; Dose-Response Relationship, Drug; Essential Tremor; Female; Gap Junction delta-2 Protein; Gap Junctions; Glycyrrhizic Acid; Harmaline; Heptanol; Injections, Subcutaneous; Mefloquine; Mice; Mice, Inbred ICR; Olivary Nucleus	2006
Adaptation of a multi-drug resistant strain of Plasmodium falciparum from Peru to Aotus lemurinus griseimembra, A. nancymaae, and A. vociferans monkeys. The American journal of tropical medicine and hygiene, 2007, Volume: 77, Issue:2 Topics: Animals; Antimalarials; Aotidae; Chloroquine; Cytochromes b; Dihydropteroate Synthase; Disease Models, Animal; DNA, Protozoan; Drug Resistance, Multiple; Humans; Malaria, Falciparum; Mefloquine; Monkey Diseases; Parasitemia; Peru; Plasmodium falciparum; Sequence Analysis, DNA; Tetrahydrofolate Dehydrogenase	2007
Anemia and antibodies to the 19-kDa fragment of MSP1 during Plasmodium falciparum infection in Aotus monkeys. Comparative medicine, 2007, Volume: 57, Issue:4 Topics: Anemia; Animals; Antibodies, Protozoan; Antimalarials; Aotidae; Disease Models, Animal; Erythrocytes; Malaria, Falciparum; Mefloquine; Merozoite Surface Protein 1; Monkey Diseases; Parasitemia; Plasmodium falciparum	2007
Comparison of beta-artemether and beta-arteether against malaria parasites in vitro and in vivo. The American journal of tropical medicine and hygiene, 1993, Volume: 48, Issue:3 Topics: Animals; Antimalarials; Aotus trivirgatus; Artemether; Artemisinins; Chloroquine; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Malaria; Malaria, Falciparum; Male; Mefloquine; Mice; Plasmodium berghei; Plasmodium falciparum; Sesquiterpenes; Structure-Activity Relationship	1993
Testing the efficacy of a recombinant merozoite surface protein (MSP-1(19) of Plasmodium vivax in Saimiri boliviensis monkeys. The American journal of tropical medicine and hygiene, 1999, Volume: 60, Issue:3 Topics: Adjuvants, Immunologic; Animals; Antimalarials; Disease Models, Animal; Female; Immunization; Malaria Vaccines; Malaria, Vivax; Male; Mefloquine; Merozoite Surface Protein 1; Parasitemia; Plasmodium vivax; Saimiri; Splenectomy; Vaccines, Synthetic	1999
Adaptation of a chloroquine-resistant strain of Plasmodium vivax from Indonesia to New World monkeys. The American journal of tropical medicine and hygiene, 2000, Volume: 62, Issue:4 Topics: Adaptation, Physiological; Adult; Amodiaquine; Animals; Antimalarials; Aotidae; Child; Chloroquine; Disease Models, Animal; Drug Resistance; Female; Humans; Indonesia; Malaria, Vivax; Male; Mefloquine; Parasitemia; Plasmodium vivax; Saimiri; Splenectomy	2000
Antimalarial drugs clear resistant parasites from partially immune hosts. Antimicrobial agents and chemotherapy, 2001, Volume: 45, Issue:10 Topics: Animals; Antimalarials; Chloroquine; Disease Models, Animal; Drug Resistance; Immunization; Malaria; Mefloquine; Mice; Plasmodium chabaudi	2001
The in vitro and in vivo effects of mefloquine on Trypanosoma brucei brucei. Journal of hygiene, epidemiology, microbiology, and immunology, 1992, Volume: 36, Issue:2 Topics: Animals; Cells, Cultured; Disease Models, Animal; Drug Administration Schedule; Kidney; Male; Mefloquine; Mice; Trypanosoma brucei brucei; Trypanosomiasis, African	1992
Adaptation of the Indochina I/CDC strain of Plasmodium falciparum to the squirrel monkey (Saimiri sciureus). The American journal of tropical medicine and hygiene, 1986, Volume: 35, Issue:3 Topics: Animals; Aotus trivirgatus; Cebidae; Chloroquine; Disease Models, Animal; Drug Resistance; Malaria; Mefloquine; Plasmodium falciparum; Pyrimethamine; Quinolines; Saimiri; Splenectomy; Sulfadoxine	1986