Page last updated: 2024-08-23

mefloquine and Astrocytoma, Grade IV

mefloquine has been researched along with Astrocytoma, Grade IV in 5 studies

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's4 (80.00)24.3611
2020's1 (20.00)2.80

Authors

AuthorsStudies
Dos Santos, JL; Fernandes, BC; Fernandes, GFDS; Valente, V1
Huang, B; Wan, B; Wu, Z; Zhang, X1
Aldape, KD; Alfred Yung, WK; Conrad, CA; de Groot, JF; Gilbert, MR; Groves, MD; Hess, KR; Loghin, ME; Mammoser, AG; Maraka, S; Melguizo-Gavilanes, I; O'Brien, BJ; Penas-Prado, M; Puduvalli, VK; Sulman, EP; Tremont-Lukats, IW1
Nevin, RL1
Groves, MD; Maraka, S; Penas-Prado, M1

Reviews

1 review(s) available for mefloquine and Astrocytoma, Grade IV

ArticleYear
Recent advances in the discovery of small molecules targeting glioblastoma.
    European journal of medicinal chemistry, 2019, Feb-15, Volume: 164

    Topics: Animals; Central Nervous System Neoplasms; Drug Discovery; Glioblastoma; Humans; Neoplastic Stem Cells

2019

Trials

1 trial(s) available for mefloquine and Astrocytoma, Grade IV

ArticleYear
Phase 1 lead-in to a phase 2 factorial study of temozolomide plus memantine, mefloquine, and metformin as postradiation adjuvant therapy for newly diagnosed glioblastoma.
    Cancer, 2019, 02-01, Volume: 125, Issue:3

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Chemotherapy, Adjuvant; Clinical Trials, Phase II as Topic; Female; Glioblastoma; Humans; Male; Maximum Tolerated Dose; Mefloquine; Memantine; Metformin; Middle Aged; Progression-Free Survival; Radiotherapy, Adjuvant; Research Design; Temozolomide; Treatment Outcome; Young Adult

2019

Other Studies

3 other study(ies) available for mefloquine and Astrocytoma, Grade IV

ArticleYear
Mefloquine as a dual inhibitor of glioblastoma angiogenesis and glioblastoma via disrupting lysosomal function.
    Biochemical and biophysical research communications, 2021, 11-26, Volume: 580

    Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Brain Neoplasms; Cell Line, Tumor; Glioblastoma; Humans; Male; Mefloquine; Mice, SCID; Neovascularization, Pathologic

2021
Unexpectedly low rates of neuropsychiatric adverse effects associated with mefloquine repurposed for the treatment of glioblastoma.
    Cancer, 2019, 04-15, Volume: 125, Issue:8

    Topics: Glioblastoma; Humans; Mefloquine; Memantine; Metformin; Temozolomide

2019
Reply to Unexpectedly low rates of neuropsychiatric adverse effects associated with mefloquine repurposed for the treatment of glioblastoma.
    Cancer, 2019, 04-15, Volume: 125, Issue:8

    Topics: Glioblastoma; Humans; Mefloquine; Memantine; Metformin; Temozolomide

2019