mefenamic acid has been researched along with Stomach Ulcer in 9 studies
Mefenamic Acid: A non-steroidal anti-inflammatory agent with analgesic, anti-inflammatory, and antipyretic properties. It is an inhibitor of cyclooxygenase.
mefenamic acid : An aminobenzoic acid that is anthranilic acid in which one of the hydrogens attached to the nitrogen is replaced by a 2,3-dimethylphenyl group. Although classed as a non-steroidal anti-inflammatory drug, its anti-inflammatory properties are considered to be minor. It is used to relieve mild to moderate pain, including headaches, dental pain, osteoarthritis and rheumatoid arthritis.
Stomach Ulcer: Ulceration of the GASTRIC MUCOSA due to contact with GASTRIC JUICE. It is often associated with HELICOBACTER PYLORI infection or consumption of nonsteroidal anti-inflammatory drugs (NSAIDS).
| Excerpt | Relevance | Reference |
|---|---|---|
| " These findings suggest that the prodrugs 3a and 3b synthesized might be used as biolabile prodrugs of mefenamic acid with increased bioavailability and less gastrointestinal side effects." | 1.33 | Glyceride derivatives as potential prodrugs: synthesis, biological activity and kinetic studies of glyceride derivatives of mefenamic acid. ( Akhter, M; Khan, MS, 2005) |
| "These duodenal ulcers were also prevented by dmPGE2." | 1.27 | Effect of 16,16-dimethyl PGE2 on renal papillary necrosis and gastrointestinal ulcerations (gastric, duodenal, intestinal) produced in rats by mefenamic acid. ( Davis, JP; Elliott, G; Field, SO; Lancaster, C; Purmalis, A; Robert, A; Whited, BA, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (55.56) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (22.22) | 29.6817 |
| 2010's | 2 (22.22) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Rasheed, A | 1 |
| Ashok Kumar, CK | 1 |
| Hegazy, GH | 1 |
| Ali, HI | 1 |
| Khan, MS | 1 |
| Akhter, M | 1 |
| Künzel, AR | 1 |
| Haschke, M | 1 |
| Surber, C | 1 |
| Lambrecht, JT | 1 |
| Maizumi, H | 1 |
| Kobayashi, K | 1 |
| Chono, S | 1 |
| Yamada, H | 1 |
| Elliott, G | 1 |
| Whited, BA | 1 |
| Purmalis, A | 1 |
| Davis, JP | 1 |
| Field, SO | 1 |
| Lancaster, C | 1 |
| Robert, A | 1 |
| Cosh, JA | 1 |
| Jahn, U | 1 |
| Adrian, RW | 1 |
1 review available for mefenamic acid and Stomach Ulcer
| Article | Year |
|---|---|
[Mefenamic acid and other non-steroidal anti-inflammatory agents in dental practice. A review of the literature].
Topics: Acute Kidney Injury; Anti-Inflammatory Agents, Non-Steroidal; Humans; Mefenamic Acid; Pharmaceutical | 2007 |
8 other studies available for mefenamic acid and Stomach Ulcer
| Article | Year |
|---|---|
Tyrosine and glycine derivatives as potential prodrugs: design, synthesis, and pharmacological evaluation of amide derivatives of mefenamic acid.
Topics: Amides; Analgesics, Non-Narcotic; Animals; Anti-Inflammatory Agents, Non-Steroidal; Drug Design; Ede | 2010 |
Design, synthesis, biological evaluation, and comparative Cox1 and Cox2 docking of p-substituted benzylidenamino phenyl esters of ibuprofenic and mefenamic acids.
Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Drug Design; Edema; Ibupr | 2012 |
Glyceride derivatives as potential prodrugs: synthesis, biological activity and kinetic studies of glyceride derivatives of mefenamic acid.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Biological Availability; Carrageenan; Chromatograp | 2005 |
[How to choose anti-inflammatory, analgesic agents].
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Female; Gingivitis; Humans; Male; Mefenamic Acid; Mid | 1984 |
Mepirizole, a non-steroidal antiinflammatory compound, its ulcerogenicity and inhibitory action on lesions induced by acidic antiinflammatory agents in the rat stomach.
Topics: Animals; Anti-Inflammatory Agents; Dose-Response Relationship, Drug; Epirizole; Fibrinolysis; Gastri | 1980 |
Effect of 16,16-dimethyl PGE2 on renal papillary necrosis and gastrointestinal ulcerations (gastric, duodenal, intestinal) produced in rats by mefenamic acid.
Topics: 16,16-Dimethylprostaglandin E2; Animals; Duodenal Ulcer; Female; Intestinal Diseases; Kidney Papilla | 1986 |
Anti-inflammatory drugs in rheumatic diseases.
Topics: Adrenocorticotropic Hormone; Anti-Inflammatory Agents; Antimalarials; Arthritis, Rheumatoid; Aspirin | 1974 |
[Pharmacological and toxicological testing of new anti-inflammatory agent azapropazon=3-dimethylamine-7-methyl-1,2-(n-propylmalonyl)-1,2-dihydro-1,2,4-benzotriazine].
Topics: Abnormalities, Drug-Induced; Analgesics; Anesthetics, Local; Animals; Anti-Inflammatory Agents; Bloo | 1969 |