Page last updated: 2024-10-30

mefenamic acid and Renal Insufficiency

mefenamic acid has been researched along with Renal Insufficiency in 1 studies

Mefenamic Acid: A non-steroidal anti-inflammatory agent with analgesic, anti-inflammatory, and antipyretic properties. It is an inhibitor of cyclooxygenase.
mefenamic acid : An aminobenzoic acid that is anthranilic acid in which one of the hydrogens attached to the nitrogen is replaced by a 2,3-dimethylphenyl group. Although classed as a non-steroidal anti-inflammatory drug, its anti-inflammatory properties are considered to be minor. It is used to relieve mild to moderate pain, including headaches, dental pain, osteoarthritis and rheumatoid arthritis.

Renal Insufficiency: Conditions in which the KIDNEYS perform below the normal level in the ability to remove wastes, concentrate URINE, and maintain ELECTROLYTE BALANCE; BLOOD PRESSURE; and CALCIUM metabolism. Renal insufficiency can be classified by the degree of kidney damage (as measured by the level of PROTEINURIA) and reduction in GLOMERULAR FILTRATION RATE.

Research Excerpts

ExcerptRelevanceReference
" As a guide to determining dosing regimens in pediatric studies, the verified PBPK model, along with UGT enzyme ontogeny maturation understanding, was used for predictions of dapagliflozin monotherapy exposures in pediatric subjects aged 1 month to 18 years that best matched exposure in adult patients with a 10-mg single dose of dapagliflozin."3.01Model-Informed Pediatric Dose Selection for Dapagliflozin by Incorporating Developmental Changes. ( Boulton, DW; Jo, H; Parkinson, J; Pilla Reddy, V; Tang, W, 2021)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's1 (100.00)2.80

Authors

AuthorsStudies
Jo, H1
Pilla Reddy, V1
Parkinson, J1
Boulton, DW1
Tang, W1

Trials

1 trial available for mefenamic acid and Renal Insufficiency

ArticleYear
Model-Informed Pediatric Dose Selection for Dapagliflozin by Incorporating Developmental Changes.
    CPT: pharmacometrics & systems pharmacology, 2021, Volume: 10, Issue:2

    Topics: Administration, Oral; Adolescent; Antibiotics, Antitubercular; Area Under Curve; Benzhydryl Compound

2021