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mefenamic acid and Pregnancy

mefenamic acid has been researched along with Pregnancy in 16 studies

Mefenamic Acid: A non-steroidal anti-inflammatory agent with analgesic, anti-inflammatory, and antipyretic properties. It is an inhibitor of cyclooxygenase.
mefenamic acid : An aminobenzoic acid that is anthranilic acid in which one of the hydrogens attached to the nitrogen is replaced by a 2,3-dimethylphenyl group. Although classed as a non-steroidal anti-inflammatory drug, its anti-inflammatory properties are considered to be minor. It is used to relieve mild to moderate pain, including headaches, dental pain, osteoarthritis and rheumatoid arthritis.

Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.

Research Excerpts

ExcerptRelevanceReference
" In a second case report we describe, in a 61-year-old patient suffering from aspirin-sensitive asthma, recurrent ciliary body oedema with a marked spastic component which was triggered by the medications acetazolamide, dipivefrine and pilocarpine."3.69Drug-induced ciliary body oedema: a new theory. ( Krieg, PH; Schipper, I, 1996)
"To assess the possible effect upon the fetus of maternal ingestion of the prostaglandin synthetase inhibitor, mefenamic acid, taken during mid-pregnancy (15-22 weeks) to prevent spontaneous abortion, samples of fetal blood were collected at fetoscopy from 13 treated and 14 untreated control cases."3.67Prostaglandins in the fetal circulation following maternal ingestion of a prostaglandin synthetase inhibitor during mid-pregnancy. ( Graf, AK; MacKenzie, IZ; Mitchell, MD, 1985)
"Mefenamic acid appears to increase survival rates especially when crushing is performed after 31 days, although the twin of apparently successful crushings at this stage may be lost between Days 50 and 70."1.26Termination of twin gestation by blastocyst crush in the broodmare. ( Roberts, CJ, 1982)

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-199013 (81.25)18.7374
1990's3 (18.75)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Roberts, CJ1
Gupta, U1
Malhotra, N1
Saini, KC1
Chaudhury, RR1
Krieg, PH1
Schipper, I1
Huskisson, EC1
Guillebaud, J1
Smith, ID1
Temple, DM1
Shearman, RP1
Mital, P2
Garg, S1
Khuteta, RP1
Khuteta, S1
MacKenzie, IZ1
Graf, AK1
Mitchell, MD1
Harrison, RF1
Brennan, M1
Ledger, WL1
Webster, MA1
Anderson, AB1
Turnbull, AC1
Seymour, RA1
Waltman, R1
Tricomi, V1
Buchanan, RA1
Eaton, CJ1
Koeff, ST1
Kinkel, AW1
Glazko, AJ1

Reviews

1 review available for mefenamic acid and Pregnancy

ArticleYear
Antiinflammatory drugs.
    Seminars in arthritis and rheumatism, 1977, Volume: 7, Issue:1

    Topics: Adult; Anti-Inflammatory Agents; Apazone; Arthritis, Rheumatoid; Aspirin; Benzylidene Compounds; Chi

1977

Trials

3 trials available for mefenamic acid and Pregnancy

ArticleYear
Mefenamic acid in prevention of premature labour.
    Journal of the Royal Society of Health, 1992, Volume: 112, Issue:5

    Topics: Adolescent; Adult; Double-Blind Method; Female; Humans; Mefenamic Acid; Obstetric Labor, Premature;

1992
Comparison of two formulations of lignocaine spray with mefenamic acid in the relief of post-episiotomy pain: a placebo-controlled study.
    Current medical research and opinion, 1987, Volume: 10, Issue:6

    Topics: Adult; Aerosols; Analgesia; Clinical Trials as Topic; Double-Blind Method; Episiotomy; Female; Human

1987
Letter: Pentazocine, mefenamic acid and hypertonic-saline abortion.
    Lancet (London, England), 1974, Aug-24, Volume: 2, Issue:7878

    Topics: Abortion, Induced; Female; Humans; Hypertonic Solutions; Mefenamic Acid; Pain; Pentazocine; Pregnanc

1974

Other Studies

12 other studies available for mefenamic acid and Pregnancy

ArticleYear
Discussion on the pharmacology of the fenamates.
    Annals of physical medicine, 1966, Volume: Suppl

    Topics: Abnormalities, Drug-Induced; Analgesia; Animals; Anti-Inflammatory Agents; Arthritis, Rheumatoid; As

1966
Termination of twin gestation by blastocyst crush in the broodmare.
    Journal of reproduction and fertility. Supplement, 1982, Volume: 32

    Topics: Abortion, Induced; Animals; Blastocyst; Fallopian Tubes; Female; Fetal Resorption; Horses; Mefenamic

1982
Experimental studies with a thread containing mefenamic acid introduced into the rat uterus.
    Indian journal of experimental biology, 1981, Volume: 19, Issue:5

    Topics: Animals; Embryo Implantation; Female; Leukocyte Count; Mefenamic Acid; Pregnancy; Rats; Uterus

1981
Drug-induced ciliary body oedema: a new theory.
    Eye (London, England), 1996, Volume: 10 ( Pt 1)

    Topics: Acetazolamide; Adult; Asthma; Chlorthalidone; Ciliary Body; Diuretics; Edema; Epinephrine; Female; H

1996
Premature closure of the fetal ductus arteriosus after maternal use of non-steroidal anti-inflammatory drugs. Adverse Drug Reactions Advisory Committee.
    The Medical journal of Australia, 1998, Sep-07, Volume: 169, Issue:5

    Topics: Adverse Drug Reaction Reporting Systems; Anti-Inflammatory Agents, Non-Steroidal; Australia; Diclofe

1998
Suction termination of pregnancy under local anesthesia.
    British medical journal, 1979, Apr-28, Volume: 1, Issue:6171

    Topics: Abortion, Therapeutic; Anesthesia, Local; Anesthesia, Obstetrical; Female; Humans; Mefenamic Acid; P

1979
The antagonism by anti-inflammatory analgesics of prostaglandin f 2 alpha-induced contractions of human and rabbit myometrium in vitro.
    Prostaglandins, 1975, Volume: 10, Issue:1

    Topics: Abortion, Induced; Animals; Anti-Inflammatory Agents; Aspirin; Drug Antagonism; Female; Ibuprofen; I

1975
Prostaglandins in the fetal circulation following maternal ingestion of a prostaglandin synthetase inhibitor during mid-pregnancy.
    International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 1985, Volume: 23, Issue:6

    Topics: 6-Ketoprostaglandin F1 alpha; Abortion, Spontaneous; Cyclooxygenase Inhibitors; Dinoprost; Dinoprost

1985
Effect of inhibition of prostaglandin synthesis on cervical softening and uterine activity during ovine parturition resulting from progesterone withdrawal induced by epostane.
    The Journal of endocrinology, 1985, Volume: 105, Issue:2

    Topics: 3-Hydroxysteroid Dehydrogenases; Animals; Cervix Uteri; Estradiol; Female; Labor, Obstetric; Mefenam

1985
Prescribing analgesics.
    British dental journal, 1985, Sep-21, Volume: 159, Issue:6

    Topics: Acetaminophen; Aged; Analgesics; Anticoagulants; Aspirin; Child; Codeine; Diflunisal; Drug Hypersens

1985
The breast milk excretion of mefenamic acid.
    Current therapeutic research, clinical and experimental, 1968, Volume: 10, Issue:11

    Topics: Anti-Inflammatory Agents; Breast Feeding; Female; Humans; Infant, Newborn; Lactation; Mefenamic Acid

1968
Experimental observations on flufenamic, mefenamic and meclofenamic acids. 3. Metabolic disposition.
    Annals of physical medicine, 1966, Volume: Suppl

    Topics: Adult; Animals; Anti-Inflammatory Agents; Bile; Biliary Fistula; Blood Proteins; Carbon Isotopes; Ch

1966