mefenamic acid has been researched along with Patency of the Ductus Arteriosus in 6 studies
Mefenamic Acid: A non-steroidal anti-inflammatory agent with analgesic, anti-inflammatory, and antipyretic properties. It is an inhibitor of cyclooxygenase.
mefenamic acid : An aminobenzoic acid that is anthranilic acid in which one of the hydrogens attached to the nitrogen is replaced by a 2,3-dimethylphenyl group. Although classed as a non-steroidal anti-inflammatory drug, its anti-inflammatory properties are considered to be minor. It is used to relieve mild to moderate pain, including headaches, dental pain, osteoarthritis and rheumatoid arthritis.
| Excerpt | Relevance | Reference |
|---|---|---|
| " There were marked inter-individual differences in some of the pharmacokinetic parameters after the first dose; peak plasma concentration (Cmax) varied from 1." | 1.29 | Pharmacokinetics of mefenamic acid in preterm infants with patent ductus arteriosus. ( Ito, K; Niida, Y; Owada, E; Sato, J; Umetsu, M, 1994) |
| " We recommend the use of MA for closure of symptomatic PDA in preterms, especially in those cases where indomethacin is not tolerated or when minute titration of its dosage is impracticable." | 1.28 | Therapy of symptomatic patent ductus arteriosus in preterms using mefenemic acid and indomethacin. ( Merchant, RH; Sakhalkar, VS, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (16.67) | 18.7374 |
| 1990's | 5 (83.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ito, K | 5 |
| Niida, Y | 3 |
| Sato, J | 3 |
| Owada, E | 3 |
| Umetsu, M | 3 |
| Shimada, S | 1 |
| Kasai, T | 1 |
| Konishi, M | 1 |
| Fujiwara, T | 1 |
| Merchant, RH | 2 |
| Sakhalkar, VS | 2 |
| Kudo, N | 1 |
| Kikuta, T | 1 |
| Wakamatsu, A | 1 |
6 other studies available for mefenamic acid and Patency of the Ductus Arteriosus
| Article | Year |
|---|---|
Pharmacokinetics of mefenamic acid in preterm infants with patent ductus arteriosus.
Topics: Administration, Oral; Ductus Arteriosus, Patent; Humans; Infant, Newborn; Infant, Premature, Disease | 1994 |
Effects of patent ductus arteriosus on left ventricular output and organ blood flows in preterm infants with respiratory distress syndrome treated with surfactant.
Topics: Blood Flow Velocity; Cardiac Output; Case-Control Studies; Ductus Arteriosus, Patent; Echocardiograp | 1994 |
Patent ductus arteriosus in the newborn.
Topics: Ductus Arteriosus, Patent; Humans; Infant, Newborn; Mefenamic Acid | 1994 |
Urinary excretion of mefenamic acid and its metabolites including their esterglucuronides in preterm infants undergoing mefenamic acid therapy.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Chromatography, High Pressure Liquid; Ductus Arteriosus, Pa | 1997 |
Therapy of symptomatic patent ductus arteriosus in preterms using mefenemic acid and indomethacin.
Topics: Ductus Arteriosus, Patent; Humans; Indomethacin; Infant, Newborn; Infant, Premature, Diseases; Mefen | 1992 |
Simple, rapid and sensitive reversed-phase high-performance liquid chromatographic method for the determination of mefenamic acid in plasma.
Topics: Chromatography, High Pressure Liquid; Ductus Arteriosus, Patent; Humans; Infant, Newborn; Infant, Pr | 1989 |