mefenamic acid has been researched along with Pain, Postoperative in 24 studies
Mefenamic Acid: A non-steroidal anti-inflammatory agent with analgesic, anti-inflammatory, and antipyretic properties. It is an inhibitor of cyclooxygenase.
mefenamic acid : An aminobenzoic acid that is anthranilic acid in which one of the hydrogens attached to the nitrogen is replaced by a 2,3-dimethylphenyl group. Although classed as a non-steroidal anti-inflammatory drug, its anti-inflammatory properties are considered to be minor. It is used to relieve mild to moderate pain, including headaches, dental pain, osteoarthritis and rheumatoid arthritis.
Pain, Postoperative: Pain during the period after surgery.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Mefenamic acid is a non-steroidal anti-inflammatory drug (NSAID)." | 6.47 | Single dose oral mefenamic acid for acute postoperative pain in adults. ( Derry, S; McQuay, HJ; Moll, R; Moore, RA, 2011) |
| "The combination of ibuprofen/paracetamol, taken immediately after initial endodontic therapy and root canal preparation in teeth with irreversible pulpitis, reduced post-endodontic pain (ClinicalTrials." | 5.22 | Double-blind Randomized Placebo-controlled Clinical Trial of Efficiency of Nonsteroidal Anti-inflammatory Drugs in the Control of Post-endodontic Pain. ( Abubakr, NH; Elzaki, WM; Ibrahim, YE; Ziada, HM, 2016) |
| "Patients' satisfaction with postoperative pain treatment was evaluated 1 month postoperatively." | 2.73 | Alleviation of wound pain after surgeries for obstructive sleep apnea. ( Chen, NH; Fang, TJ; Huang, HC; Lee, LA; Li, HY; Lo, CC; Wang, PC, 2007) |
| "Pelvic pain was assessed, with a 100 mm visual analogue scale, at 1 hour, at hospital discharge, and time of first analgesia or any other time analgesia was demanded." | 2.68 | Local anaesthetic on Filshie clips for pain relief after tubal sterilisation: a randomised double-blind controlled trial. ( Breeson, AJ; Ezeh, UO; Lamb, MD; Martin, JL; Shoulder, VS; Vellacott, ID, 1995) |
| "Aspirin was not consistently superior to the placebo." | 2.65 | Control of pain resulting from endodontic therapy: a double-blind, placebo-controlled study. ( Dowson, J; Petrick, TJ; Rowe, NH; Shekter, MA; Spencer, J; Turner, JL, 1980) |
| "Mefenamic acid was clearly superior to placebo and equalled or exceeded the ability of aspirin to control postsurgical pain in the parameters measured." | 2.65 | Control of pain by mefenamic acid following removal of impacted molar. A double-blind, placebo-controlled study. ( Cudmore, CL; Rowe, NH; Turner, JL, 1981) |
| "Mefenamic acid is a non-steroidal anti-inflammatory drug (NSAID)." | 2.47 | Single dose oral mefenamic acid for acute postoperative pain in adults. ( Derry, S; McQuay, HJ; Moll, R; Moore, RA, 2011) |
| "Postoperative pain is a common and predictable occurrence after maxillofacial surgery." | 1.51 | Comparison of Intra-Socket Bupivacaine Administration Versus Oral Mefenamic Acid Capsule for Postoperative Pain Management Following Removal of Impacted Mandibular Third Molars. ( Babaei, H; Faradmal, J; Jamalpour, MR; Talimkhani, I, 2019) |
| "Fluproquazone was better tolerated than mefenamic acid: one and four patients, respectively, experienced side-effects in the two treatment groups." | 1.26 | Comparative study of fluproquazone in the management of post-operative pain. ( Lataste, X; Mohing, W; Suckert, R, 1981) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (45.83) | 18.7374 |
| 1990's | 4 (16.67) | 18.2507 |
| 2000's | 4 (16.67) | 29.6817 |
| 2010's | 4 (16.67) | 24.3611 |
| 2020's | 1 (4.17) | 2.80 |
| Authors | Studies |
|---|---|
| Singh, R | 2 |
| Jayam, C | 1 |
| Nazeer, J | 1 |
| Iqubal, MA | 1 |
| Singh, S | 1 |
| Talimkhani, I | 1 |
| Jamalpour, MR | 1 |
| Babaei, H | 1 |
| Faradmal, J | 1 |
| Elzaki, WM | 1 |
| Abubakr, NH | 1 |
| Ziada, HM | 1 |
| Ibrahim, YE | 1 |
| Cooper, SA | 1 |
| Desjardins, PJ | 1 |
| Moll, R | 1 |
| Derry, S | 1 |
| Moore, RA | 1 |
| McQuay, HJ | 1 |
| Pajarola, G | 1 |
| Riva, C | 1 |
| Good, M | 1 |
| Grätz, KW | 1 |
| Wu, WC | 1 |
| Hsu, KH | 1 |
| Chen, TL | 1 |
| Hwang, YS | 1 |
| Lin, KK | 1 |
| Li, LM | 1 |
| Shih, CP | 1 |
| Lai, CC | 1 |
| Lee, LA | 1 |
| Wang, PC | 1 |
| Chen, NH | 1 |
| Fang, TJ | 1 |
| Huang, HC | 1 |
| Lo, CC | 1 |
| Li, HY | 1 |
| Maeda, K | 1 |
| Akamine, A | 1 |
| Kaida, H | 1 |
| Honda, N | 1 |
| Kishi, T | 1 |
| Onimura, K | 1 |
| Nagamine, N | 1 |
| Yamamoto, J | 1 |
| Aono, M | 1 |
| Haraga, Y | 1 |
| Ohnishi, M | 1 |
| Kawai, T | 1 |
| Ogawa, N | 1 |
| Valdez, EV | 1 |
| Mohing, W | 1 |
| Suckert, R | 1 |
| Lataste, X | 1 |
| Rowe, NH | 2 |
| Shekter, MA | 1 |
| Turner, JL | 2 |
| Spencer, J | 1 |
| Dowson, J | 1 |
| Petrick, TJ | 1 |
| Cudmore, CL | 1 |
| Ezeh, UO | 1 |
| Shoulder, VS | 1 |
| Martin, JL | 1 |
| Breeson, AJ | 1 |
| Lamb, MD | 1 |
| Vellacott, ID | 1 |
| McSwiney, MM | 1 |
| Joshi, GP | 1 |
| Kenny, P | 1 |
| McCarroll, SM | 1 |
| Lownie, JF | 1 |
| Lownie, MA | 1 |
| Reinach, SG | 1 |
| Wraith, A | 1 |
| Ragot, JP | 1 |
| Conn, IG | 1 |
| Marshall, AH | 1 |
| Yadav, SN | 1 |
| Daly, JC | 1 |
| Jaffer, M | 1 |
| Harrison, RF | 1 |
| Brennan, M | 1 |
| Seymour, RA | 1 |
| Fassolt, A | 1 |
| Vaidya, AB | 1 |
| Sheth, MS | 1 |
| Manghani, KK | 1 |
| Shroff, P | 1 |
| Vora, KK | 1 |
| Sheth, UK | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Efficacy of Pain Control Following Root Canal Treatment Using Paracetamol Alone and in Combination With Three Different Non-Steroidal Anti-Inflammatory Analgesics[NCT02417337] | Phase 2 | 170 participants (Actual) | Interventional | 2012-08-31 | Completed | ||
| Effect of Preoperative, Single-dose Diclofenac Potassium on Postoperative Endodontic Pain in Patients With Symptomatic Irreversible Pulpitis: A Double Blind Randomized Controlled Trial[NCT03341260] | Phase 2/Phase 3 | 70 participants (Actual) | Interventional | 2016-12-31 | Completed | ||
| Analgesic Efficacy of Preoperative Oral Administration of Dexketoprofen Trometamol in Third Molar Surgery, Compared to Postoperative Administration[NCT02380001] | Phase 4 | 60 participants (Actual) | Interventional | 2015-01-31 | Completed | ||
| A Full-Factorial, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group, Single-Dose Efficacy and Safety Study of an Acetaminophen/Naproxen Sodium Fixed Combination, Acetaminophen, and Naproxen Sodium in Postoperative Dental Pain[NCT05761574] | Phase 3 | 440 participants (Anticipated) | Interventional | 2023-05-22 | Recruiting | ||
| Patient Comfort Using Green (532 nm) Versus Yellow (577 nm) Laser Indirect Ophthalmoscopy Panretinal Photocoagulation for Proliferative Diabetic Retinopathy[NCT02995629] | 40 participants (Actual) | Interventional | 2016-03-31 | Completed | |||
| An Observational Prospective Study of Comparing Pain Responses With Pattern Laser Platform and Conventional Laser System During the Panretinal Photocoagulation in Proliferative Diabetic Retinopathy[NCT02645383] | 30 participants (Actual) | Interventional | 2014-05-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for mefenamic acid and Pain, Postoperative
| Article | Year |
|---|---|
Single dose oral mefenamic acid for acute postoperative pain in adults.
Topics: Acute Disease; Administration, Oral; Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Humans | 2011 |
15 trials available for mefenamic acid and Pain, Postoperative
| Article | Year |
|---|---|
Double-blind Randomized Placebo-controlled Clinical Trial of Efficiency of Nonsteroidal Anti-inflammatory Drugs in the Control of Post-endodontic Pain.
Topics: Acetaminophen; Adult; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Dose- | 2016 |
Double-blind Randomized Placebo-controlled Clinical Trial of Efficiency of Nonsteroidal Anti-inflammatory Drugs in the Control of Post-endodontic Pain.
Topics: Acetaminophen; Adult; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Dose- | 2016 |
Double-blind Randomized Placebo-controlled Clinical Trial of Efficiency of Nonsteroidal Anti-inflammatory Drugs in the Control of Post-endodontic Pain.
Topics: Acetaminophen; Adult; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Dose- | 2016 |
Double-blind Randomized Placebo-controlled Clinical Trial of Efficiency of Nonsteroidal Anti-inflammatory Drugs in the Control of Post-endodontic Pain.
Topics: Acetaminophen; Adult; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Dose- | 2016 |
[Pain management after third molar extraction. Observations of the use of mefenamic acid and rofecoxib in the treatment of postoperative pain in the dental office].
Topics: Adult; Ambulatory Surgical Procedures; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase 2; Cy | 2003 |
Interventions for relieving pain associated with panretinal photocoagulation: a prospective randomized trial.
Topics: Acetaminophen; Aged; Analgesia; Anesthesia, Local; Anesthetics, Local; Anti-Inflammatory Agents, Non | 2006 |
Interventions for relieving pain associated with panretinal photocoagulation: a prospective randomized trial.
Topics: Acetaminophen; Aged; Analgesia; Anesthesia, Local; Anesthetics, Local; Anti-Inflammatory Agents, Non | 2006 |
Interventions for relieving pain associated with panretinal photocoagulation: a prospective randomized trial.
Topics: Acetaminophen; Aged; Analgesia; Anesthesia, Local; Anesthetics, Local; Anti-Inflammatory Agents, Non | 2006 |
Interventions for relieving pain associated with panretinal photocoagulation: a prospective randomized trial.
Topics: Acetaminophen; Aged; Analgesia; Anesthesia, Local; Anesthetics, Local; Anti-Inflammatory Agents, Non | 2006 |
Alleviation of wound pain after surgeries for obstructive sleep apnea.
Topics: Adult; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Electrocoagulation; Female; Huma | 2007 |
[A preliminary study on the effective dose and safety of zomepirac sodium. Pain following minor surgery and tooth extraction in the field of dentistry].
Topics: Adolescent; Adult; Aged; Clinical Trials as Topic; Double-Blind Method; Humans; Mefenamic Acid; Midd | 1983 |
Double-blind comparison of piroxicam and mefenamic acid in the treatment of oral surgical pain.
Topics: Adolescent; Adult; Aged; Analgesics; Clinical Trials as Topic; Double-Blind Method; Female; Humans; | 1983 |
Control of pain resulting from endodontic therapy: a double-blind, placebo-controlled study.
Topics: Adolescent; Adult; Aged; Aspirin; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Mal | 1980 |
Control of pain by mefenamic acid following removal of impacted molar. A double-blind, placebo-controlled study.
Topics: Adolescent; Adult; Aged; Aspirin; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Mal | 1981 |
Local anaesthetic on Filshie clips for pain relief after tubal sterilisation: a randomised double-blind controlled trial.
Topics: Adult; Cyclizine; Diclofenac; Double-Blind Method; Female; Gels; Humans; Laparoscopy; Lidocaine; Mef | 1995 |
Analgesia following arthroscopic knee surgery. A controlled study of intra-articular morphine, bupivacaine or both combined.
Topics: Adult; Analgesia; Arthroscopy; Bupivacaine; Cartilage, Articular; Double-Blind Method; Drug Combinat | 1993 |
Comparison of the safety and efficacy of a combination analgesic Myprodol and Ponstan in the treatment of dental pain.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non-St | 1992 |
Transcutaneous electrical nerve stimulation following appendicectomy: the placebo effect.
Topics: Adolescent; Adult; Appendectomy; Clinical Trials as Topic; Electric Stimulation Therapy; Female; Hum | 1986 |
Comparison of two formulations of lignocaine spray with mefenamic acid in the relief of post-episiotomy pain: a placebo-controlled study.
Topics: Adult; Aerosols; Analgesia; Clinical Trials as Topic; Double-Blind Method; Episiotomy; Female; Human | 1987 |
[The control of pain after tonsillectomy with mefenamic acid (author's transl)].
Topics: Adolescent; Adult; Analgesics; Humans; Mefenamic Acid; Middle Aged; Morphine Derivatives; Pain, Post | 1974 |
Double blind trial of mefenamic acid, aspirin and placebo in patients with post-operative pain.
Topics: Adolescent; Adult; Aspirin; Clinical Trials as Topic; Female; Humans; Male; Mefenamic Acid; Middle A | 1974 |
8 other studies available for mefenamic acid and Pain, Postoperative
| Article | Year |
|---|---|
Assessment of C-reactive Protein Level and Efficacy of Diclofenac Sodium and Mefenamic Acid in Relieving Pain in Mandibular Impacted Third Molar Surgery.
Topics: Anti-Inflammatory Agents, Non-Steroidal; C-Reactive Protein; Diclofenac; Double-Blind Method; Humans | 2021 |
Comparison of Intra-Socket Bupivacaine Administration Versus Oral Mefenamic Acid Capsule for Postoperative Pain Management Following Removal of Impacted Mandibular Third Molars.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Bupivacaine; Capsules; Double-Blind Method; Female; Humans; | 2019 |
The value of the dental impaction pain model in drug development.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Drug Design; Human | 2010 |
The value of the dental impaction pain model in drug development.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Drug Design; Human | 2010 |
The value of the dental impaction pain model in drug development.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Drug Design; Human | 2010 |
The value of the dental impaction pain model in drug development.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Drug Design; Human | 2010 |
[Treatment of postoperative pain. Zomepirac, mefenamic acid and placebo].
Topics: Adult; Analgesics; Double-Blind Method; Humans; Mefenamic Acid; Pain, Postoperative; Pyrroles; Rando | 1982 |
Comparative study of fluproquazone in the management of post-operative pain.
Topics: Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Method; Female; Humans; Mal | 1981 |
Association of Dental Anaesthetists. Summer Scientific Meeting Stirling, Scotland 8-9 June, 2001. ADA meeting report.
Topics: Administration, Oral; Analgesics, Opioid; Anesthesia, Dental; Anesthesia, General; Anesthetics, Intr | 2001 |
[Comparison of analgesic activity of mefenamic acid and paracetamol in treatment of pain after extraction of impacted lower 3d molar].
Topics: Acetaminophen; Adolescent; Adult; Double-Blind Method; Humans; Mandible; Mefenamic Acid; Molar, Thir | 1991 |
Prescribing analgesics.
Topics: Acetaminophen; Aged; Analgesics; Anticoagulants; Aspirin; Child; Codeine; Diflunisal; Drug Hypersens | 1985 |