mefenamic acid has been researched along with Osteoarthritis in 13 studies
Mefenamic Acid: A non-steroidal anti-inflammatory agent with analgesic, anti-inflammatory, and antipyretic properties. It is an inhibitor of cyclooxygenase.
mefenamic acid : An aminobenzoic acid that is anthranilic acid in which one of the hydrogens attached to the nitrogen is replaced by a 2,3-dimethylphenyl group. Although classed as a non-steroidal anti-inflammatory drug, its anti-inflammatory properties are considered to be minor. It is used to relieve mild to moderate pain, including headaches, dental pain, osteoarthritis and rheumatoid arthritis.
Osteoarthritis: A progressive, degenerative joint disease, the most common form of arthritis, especially in older persons. The disease is thought to result not from the aging process but from biochemical changes and biomechanical stresses affecting articular cartilage. In the foreign literature it is often called osteoarthrosis deformans.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Mefenamic acid is a non-steroidal anti-inflammatory drug able to control the symptoms of osteoarthritis (OA), but its effects on protection of cartilage and bone are still unclear." | 7.83 | Mefenamic acid decreases inflammation but not joint lesions in experimental osteoarthritis. ( Aguiar, GC; Amaral, FA; Caliari, MV; Ferreira, AJ; Queiroz-Junior, CM; Sitta, GL; Teixeira, MM, 2016) |
| "We report a case of steatorrhoea and sub-total villous atrophy, occurring during therapy with mefenamic acid." | 7.68 | Steatorrhoea and sub-total villous atrophy complicating mefenamic acid therapy. ( Peacey, SR; Walls, WD, 1992) |
| "Mefenamic acid is a non-steroidal anti-inflammatory drug able to control the symptoms of osteoarthritis (OA), but its effects on protection of cartilage and bone are still unclear." | 3.83 | Mefenamic acid decreases inflammation but not joint lesions in experimental osteoarthritis. ( Aguiar, GC; Amaral, FA; Caliari, MV; Ferreira, AJ; Queiroz-Junior, CM; Sitta, GL; Teixeira, MM, 2016) |
| "We report a case of steatorrhoea and sub-total villous atrophy, occurring during therapy with mefenamic acid." | 3.68 | Steatorrhoea and sub-total villous atrophy complicating mefenamic acid therapy. ( Peacey, SR; Walls, WD, 1992) |
| "Three patients developed autoimmune haemolytic anaemia while being treated with mefenamic acid." | 1.25 | Autoimmune haemolytic anaemia and mefenamic acid therapy. ( Bacon, PA; Myles, AB; Scott, GL, 1968) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (84.62) | 18.7374 |
| 1990's | 1 (7.69) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (7.69) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Aguiar, GC | 1 |
| Queiroz-Junior, CM | 1 |
| Sitta, GL | 1 |
| Amaral, FA | 1 |
| Teixeira, MM | 1 |
| Caliari, MV | 1 |
| Ferreira, AJ | 1 |
| CAHILL, WJ | 1 |
| HILL, RD | 1 |
| JESSOP, J | 1 |
| KENDALL, PH | 1 |
| Marks, JS | 1 |
| Gleeson, MH | 1 |
| Peacey, SR | 1 |
| Walls, WD | 1 |
| Stewart, I | 1 |
| Thomas, A | 1 |
| Barnard-Jones, K | 1 |
| Davies, RW | 1 |
| Lalla, O | 1 |
| Mann, PG | 1 |
| Welch, RB | 1 |
| Segasothy, M | 1 |
| Thyaparan, A | 1 |
| Kamal, A | 1 |
| Sivalingam, S | 1 |
| Isaacs, PE | 1 |
| Sladen, GE | 1 |
| Filipe, I | 1 |
| Aylward, M | 1 |
| Maddock, J | 1 |
| Lewis, PA | 1 |
| Dewland, PM | 1 |
| Cosh, JA | 1 |
| Buchmann, E | 1 |
| Cremoncini, C | 1 |
| Scott, GL | 1 |
| Myles, AB | 1 |
| Bacon, PA | 1 |
4 trials available for mefenamic acid and Osteoarthritis
| Article | Year |
|---|---|
Mefenamic acid compared with diclofenac sodium in elderly patients with osteoarthritis.
Topics: Aged; Aged, 80 and over; Clinical Trials as Topic; Diclofenac; Double-Blind Method; Female; Follow-U | 1988 |
Mefenamic acid versus ibuprofen in osteoarthritis--a double-blind cross-over study.
Topics: Clinical Trials as Topic; Double-Blind Method; Female; Humans; Ibuprofen; Male; Mefenamic Acid; Oste | 1986 |
Mefenamic acid and diclofenac sodium in osteoarthritis of the weight bearing joints: a double blind comparison.
Topics: Adult; Aged; Clinical Trials as Topic; Diclofenac; Double-Blind Method; Female; Humans; Male; Mefena | 1985 |
Mefenamic acid compared with indomethacin and placebo in osteoarthritis.
Topics: Anti-Inflammatory Agents; Clinical Trials as Topic; Diarrhea; Digestion; Duodenal Ulcer; Female; Fol | 1966 |
9 other studies available for mefenamic acid and Osteoarthritis
| Article | Year |
|---|---|
Mefenamic acid decreases inflammation but not joint lesions in experimental osteoarthritis.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Bone and Bones; Cartilage; Disease Models, Animal; | 2016 |
TRIAL OF MEFENAMIC ACID.
Topics: Analgesics; Analgesics, Non-Narcotic; Antipyretics; Arthritis; Arthritis, Rheumatoid; Bone Neoplasms | 1965 |
Steatorrhoea complicating therapy with mefenamic acid.
Topics: Aged; Angina Pectoris; Celiac Disease; Humans; Male; Mefenamic Acid; Nitroglycerin; Osteoarthritis | 1975 |
Steatorrhoea and sub-total villous atrophy complicating mefenamic acid therapy.
Topics: Atrophy; Celiac Disease; Humans; Male; Mefenamic Acid; Middle Aged; Osteoarthritis | 1992 |
Mefenamic acid nephropathy.
Topics: Arthritis; Female; Gout; Humans; Kidney Papillary Necrosis; Male; Mefenamic Acid; Middle Aged; Osteo | 1987 |
Mefenamic acid enteropathy.
Topics: Aged; Atrophy; Celiac Disease; Diarrhea; Female; Humans; Jejunum; Mefenamic Acid; Osteoarthritis | 1987 |
Anti-inflammatory drugs in rheumatic diseases.
Topics: Adrenocorticotropic Hormone; Anti-Inflammatory Agents; Antimalarials; Arthritis, Rheumatoid; Aspirin | 1974 |
Clinical trials of ibuprofen in Milan.
Topics: Alanine Transaminase; Anti-Inflammatory Agents; Aspartate Aminotransferases; Benzyl Compounds; Femal | 1970 |
Autoimmune haemolytic anaemia and mefenamic acid therapy.
Topics: Anemia, Hemolytic, Autoimmune; Anti-Inflammatory Agents; Antibody Formation; Arthritis, Rheumatoid; | 1968 |