mefenamic acid has been researched along with Migraine Disorders in 8 studies
Mefenamic Acid: A non-steroidal anti-inflammatory agent with analgesic, anti-inflammatory, and antipyretic properties. It is an inhibitor of cyclooxygenase.
mefenamic acid : An aminobenzoic acid that is anthranilic acid in which one of the hydrogens attached to the nitrogen is replaced by a 2,3-dimethylphenyl group. Although classed as a non-steroidal anti-inflammatory drug, its anti-inflammatory properties are considered to be minor. It is used to relieve mild to moderate pain, including headaches, dental pain, osteoarthritis and rheumatoid arthritis.
Migraine Disorders: A class of disabling primary headache disorders, characterized by recurrent unilateral pulsatile headaches. The two major subtypes are common migraine (without aura) and classic migraine (with aura or neurological symptoms). (International Classification of Headache Disorders, 2nd ed. Cephalalgia 2004: suppl 1)
| Excerpt | Relevance | Reference |
|---|---|---|
| " Each drug was given at beginning of complaint and similar dose was repeated 8 hourly at following days during the menstrual bleeding period (Total dosage used 1500 mg per day)." | 2.69 | Treatment of menstrual migraine with prostaglandin synthesis inhibitor mefenamic acid: double-blind study with placebo. ( Al-Waili, NS, 2000) |
| "Forty ambulant migraine patients were supplied with oral medication for six consecutive attacks; metoclopramide 10 mg was administered in all attacks, and paracetamol 500 mg and mefenamic acid 500 mg for three attacks each." | 2.65 | Double blind comparison of mefenamic acid and acetaminophen (paracetamol) in migraine. ( Peatfield, RC; Petty, RG; Rose, FC, 1983) |
| "Menstrually related migraine (MRM) headache is common in women and associated with substantial disability." | 2.44 | Acute treatment and prevention of menstrually related migraine headache: evidence-based review. ( Davenport, WJ; Dodick, D; Pringsheim, T, 2008) |
| "Certain constituents in migraine food triggers and non-steroidal anti-inflammatory drugs (NSAIDs) inhibit sulfotransferases (SULTs) that detoxify drugs/chemicals and play role in the metabolism of neurotransmitters." | 1.72 | Migraine susceptibility is modulated by food triggers and analgesic overuse via sulfotransferase inhibition. ( Arslan, B; Ayata, C; Bolay, H; de Morais, AL; Gulbahar, O; Topa, E; Vuralli, D, 2022) |
| "The pathophysiology of migraine is still poorly understood but it is widely accepted that various 'triggers', including fluctuations in the concentrations of circulating ovarian steroid levels, may initiate alterations in the activity of the intracranial vasculature and its efferent and afferent innervation." | 1.28 | New possibilities for anti-migraine drugs: prostanoid antagonists and progesterone-mimicking stabilizers of excitable cells. ( Leathard, HL, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (50.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (25.00) | 29.6817 |
| 2010's | 1 (12.50) | 24.3611 |
| 2020's | 1 (12.50) | 2.80 |
| Authors | Studies |
|---|---|
| Vuralli, D | 1 |
| Arslan, B | 1 |
| Topa, E | 1 |
| de Morais, AL | 1 |
| Gulbahar, O | 1 |
| Ayata, C | 1 |
| Bolay, H | 1 |
| Kaosombatwattana, U | 1 |
| Limsrivilai, J | 1 |
| Pongpaibul, A | 1 |
| Maneerattanaporn, M | 1 |
| Charatcharoenwitthaya, P | 1 |
| Pringsheim, T | 1 |
| Davenport, WJ | 1 |
| Dodick, D | 1 |
| Peatfield, RC | 1 |
| Petty, RG | 1 |
| Rose, FC | 1 |
| Al-Waili, NS | 1 |
| Leathard, HL | 1 |
| Johnson, RH | 1 |
| Hornabrook, RW | 1 |
| Lambie, DG | 1 |
| Hall, DW | 1 |
2 reviews available for mefenamic acid and Migraine Disorders
| Article | Year |
|---|---|
Severe enteropathy with villous atrophy in prolonged mefenamic acid users - a currently under-recognized in previously well-recognized complication: Case report and review of literature.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthralgia; Diarrhea; Female; Humans; Intestin | 2017 |
Acute treatment and prevention of menstrually related migraine headache: evidence-based review.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Carbazoles; Double-Blind Method; Estrogens; Evidence-Based | 2008 |
3 trials available for mefenamic acid and Migraine Disorders
| Article | Year |
|---|---|
Double blind comparison of mefenamic acid and acetaminophen (paracetamol) in migraine.
Topics: Acetaminophen; Adolescent; Adult; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Mal | 1983 |
Treatment of menstrual migraine with prostaglandin synthesis inhibitor mefenamic acid: double-blind study with placebo.
Topics: Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase Inhibitors; Double-Blind | 2000 |
Comparison of mefenamic acid and propranolol with placebo in migraine prophylaxis.
Topics: Adult; Aged; Clinical Trials as Topic; Depression; Female; Gastrointestinal Diseases; Humans; Male; | 1986 |
3 other studies available for mefenamic acid and Migraine Disorders
| Article | Year |
|---|---|
Migraine susceptibility is modulated by food triggers and analgesic overuse via sulfotransferase inhibition.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Humans; Mefenamic Acid; Migraine Disorders; Prescr | 2022 |
New possibilities for anti-migraine drugs: prostanoid antagonists and progesterone-mimicking stabilizers of excitable cells.
Topics: Arteries; Brain; Estradiol; Humans; Mefenamic Acid; Migraine Disorders; Muscle, Smooth, Vascular; Ne | 1989 |
Migraine. Mefenamic acid (ponstan) in the treatment of attacks.
Topics: Adolescent; Adult; Anti-Inflammatory Agents; Child; Child, Preschool; Female; Humans; Male; Mefenami | 1968 |