mefenamic acid has been researched along with Menorrhagia in 32 studies
Mefenamic Acid: A non-steroidal anti-inflammatory agent with analgesic, anti-inflammatory, and antipyretic properties. It is an inhibitor of cyclooxygenase.
mefenamic acid : An aminobenzoic acid that is anthranilic acid in which one of the hydrogens attached to the nitrogen is replaced by a 2,3-dimethylphenyl group. Although classed as a non-steroidal anti-inflammatory drug, its anti-inflammatory properties are considered to be minor. It is used to relieve mild to moderate pain, including headaches, dental pain, osteoarthritis and rheumatoid arthritis.
Menorrhagia: Excessive uterine bleeding during MENSTRUATION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We randomly assigned 571 women with menorrhagia to treatment with levonorgestrel-IUS or usual medical treatment (tranexamic acid, mefenamic acid, combined estrogen-progestogen, or progesterone alone)." | 9.17 | Levonorgestrel intrauterine system versus medical therapy for menorrhagia. ( Daniels, J; Gray, R; Gupta, J; Kai, J; Middleton, L; Pattison, H, 2013) |
| "To compare the efficacy and tolerability of the levonorgestrel intrauterine system (LNG IUS) with mefenamic acid in the management of objective idiopathic menorrhagia." | 9.11 | Randomised comparative trial of the levonorgestrel intrauterine system and mefenamic acid for the treatment of idiopathic menorrhagia: a multiple analysis using total menstrual fluid loss, menstrual blood loss and pictorial blood loss assessment charts. ( Reid, PC; Virtanen-Kari, S, 2005) |
| "To compare the efficacy and acceptability of ethamsylate, mefenamic acid, and tranexamic acid for treating menorrhagia." | 9.08 | Treatment of menorrhagia during menstruation: randomised controlled trial of ethamsylate, mefenamic acid, and tranexamic acid. ( Bonnar, J; Sheppard, BL, 1996) |
| "Forty women with established menorrhagia were treated with either mefenamic acid (500 mg thrice daily for 3-5 days in two cycles) or danazol (100 mg twice daily for 60 days) in an open parallel group randomized study." | 9.06 | Comparison between mefenamic acid and danazol in the treatment of established menorrhagia. ( Bonnar, J; Dockeray, CJ; Sheppard, BL, 1989) |
| "Thirty-five patients with menorrhagia were treated in a double-blind crossover study with naproxen sodium and mefenamic acid after measurement of their blood loss during control menstrual cycles." | 9.06 | Control of menorrhagia by the cyclo-oxygenase inhibitors naproxen sodium and mefenamic acid. ( Garrioch, DB; Hall, P; Maclachlan, N; Nudd, MW; Taylor, CG; Thorn, N, 1987) |
| "Thirty-six women with menorrhagia were treated with mefenamic acid during all menstrual periods for more than 1 year." | 9.05 | Long-term treatment of menorrhagia with mefenamic acid. ( Fraser, IS; Markham, R; McCarron, G; Robinson, M; Smyth, E, 1983) |
| "Sixty-nine patients with a convincing history of menorrhagia completed a 4-cycle double-blind randomized placebo-controlled crossover trial of mefenamic acid taken during menstruation." | 9.05 | Efficacy of mefenamic acid in patients with a complaint of menorrhagia. ( Elliott, PM; Fraser, IS; Markham, R; McIlveen, J; Pearse, C; Shearman, RP, 1981) |
| "We randomly assigned 571 women with menorrhagia to treatment with levonorgestrel-IUS or usual medical treatment (tranexamic acid, mefenamic acid, combined estrogen-progestogen, or progesterone alone)." | 5.17 | Levonorgestrel intrauterine system versus medical therapy for menorrhagia. ( Daniels, J; Gray, R; Gupta, J; Kai, J; Middleton, L; Pattison, H, 2013) |
| "To compare the efficacy and tolerability of the levonorgestrel intrauterine system (LNG IUS) with mefenamic acid in the management of objective idiopathic menorrhagia." | 5.11 | Randomised comparative trial of the levonorgestrel intrauterine system and mefenamic acid for the treatment of idiopathic menorrhagia: a multiple analysis using total menstrual fluid loss, menstrual blood loss and pictorial blood loss assessment charts. ( Reid, PC; Virtanen-Kari, S, 2005) |
| "Twenty-four women with IUD-induced menorrhagia were recruited and randomly allocated to treatment with either desmopressin or mefenamic acid." | 5.10 | Effectiveness and mechanism of action of desmopressin in the treatment of copper intrauterine device-related menorrhagia: a pilot study. ( Bifulco, G; De Simone, R; Di Carlo, C; Di Spiezio Sardo, A; Mercorio, F; Nappi, C; Tessitore, G, 2003) |
| "To compare the efficacy and acceptability of ethamsylate, mefenamic acid, and tranexamic acid for treating menorrhagia." | 5.08 | Treatment of menorrhagia during menstruation: randomised controlled trial of ethamsylate, mefenamic acid, and tranexamic acid. ( Bonnar, J; Sheppard, BL, 1996) |
| "A series of 45 ovulatory women with a complaint of menorrhagia were randomized into 3 treatment groups, before receiving therapy with mefenamic acid in 2 cycles and 1 of 3 other agents in 2 cycles: naproxen (group 1; n = 14), a low dose monophasic combined oral contraceptive (group 2; n = 12) or low dose danazol (group 3; n = 12)." | 5.07 | Randomized trial of 2 hormonal and 2 prostaglandin-inhibiting agents in women with a complaint of menorrhagia. ( Fraser, IS; McCarron, G, 1991) |
| "The effects of ethamsylate and mefenamic acid on menstrual blood loss were compared in a double-blind trial in 34 women with menorrhagia." | 5.07 | A comparative study of ethamsylate and mefenamic acid in dysfunctional uterine bleeding. ( Chamberlain, G; Eve, L; Freeman, R; Green, D; Kennedy, A; Price, F, 1991) |
| "A well controlled double blind prospective trial was undertaken to determine the efficacy of mefenamic acid in the treatment of menorrhagia." | 5.06 | Management of cyclical menorrhagia with prostaglandin synthetase inhibitor. ( Grover, V; Gupta, U; Kalra, S; Usha, R, 1990) |
| "Forty women with established menorrhagia were treated with either mefenamic acid (500 mg thrice daily for 3-5 days in two cycles) or danazol (100 mg twice daily for 60 days) in an open parallel group randomized study." | 5.06 | Comparison between mefenamic acid and danazol in the treatment of established menorrhagia. ( Bonnar, J; Dockeray, CJ; Sheppard, BL, 1989) |
| "Thirty-five patients with menorrhagia were treated in a double-blind crossover study with naproxen sodium and mefenamic acid after measurement of their blood loss during control menstrual cycles." | 5.06 | Control of menorrhagia by the cyclo-oxygenase inhibitors naproxen sodium and mefenamic acid. ( Garrioch, DB; Hall, P; Maclachlan, N; Nudd, MW; Taylor, CG; Thorn, N, 1987) |
| "Thirty-six women with menorrhagia were treated with mefenamic acid during all menstrual periods for more than 1 year." | 5.05 | Long-term treatment of menorrhagia with mefenamic acid. ( Fraser, IS; Markham, R; McCarron, G; Robinson, M; Smyth, E, 1983) |
| "Sixty-nine patients with a convincing history of menorrhagia completed a 4-cycle double-blind randomized placebo-controlled crossover trial of mefenamic acid taken during menstruation." | 5.05 | Efficacy of mefenamic acid in patients with a complaint of menorrhagia. ( Elliott, PM; Fraser, IS; Markham, R; McIlveen, J; Pearse, C; Shearman, RP, 1981) |
| "Treatment with mefenamic acid resulted in less volume of blood loss compared to tranexamic acid (MD -64." | 2.82 | Interventions to prevent or treat heavy menstrual bleeding or pain associated with intrauterine-device use. ( Christelle, K; Jaafar, SH; Norhayati, MN, 2022) |
| "Although there are numerous medical treatments for menorrhagia, in many instances neither the precise diagnosis nor the response to therapy have been assessed objectively." | 2.67 | The effects of mefenamic acid and norethisterone on measured menstrual blood loss. ( Cameron, IT; Haining, R; Lumsden, MA; Smith, SK; Thomas, VR, 1990) |
| "Heavy menstrual bleeding was classically defined as greater than or equal to 80 mL of blood loss per menstrual cycle." | 2.66 | Progestogen-releasing intrauterine systems for heavy menstrual bleeding. ( Bofill Rodriguez, M; Jordan, V; Lethaby, A, 2020) |
| "Menorrhagia (heavy menstrual bleeding) is a benign yet debilitating social and health condition." | 2.45 | Oral contraceptive pill for heavy menstrual bleeding. ( Brown, J; Farquhar, C, 2009) |
| "Menorrhagia is a common and important problem that has a significant impact on women's health." | 1.38 | Trends in the surgical options for the treatment of menorrhagia in Scotland: examination of health episode statistics, 2000-2008. ( Chittenden, BG; Dallas, S; Jack, SA, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (34.38) | 18.7374 |
| 1990's | 10 (31.25) | 18.2507 |
| 2000's | 5 (15.63) | 29.6817 |
| 2010's | 3 (9.38) | 24.3611 |
| 2020's | 3 (9.38) | 2.80 |
| Authors | Studies |
|---|---|
| Christelle, K | 1 |
| Norhayati, MN | 1 |
| Jaafar, SH | 1 |
| Bofill Rodriguez, M | 3 |
| Lethaby, A | 3 |
| Jordan, V | 1 |
| Farquhar, C | 2 |
| Duffy, JM | 1 |
| Wise, MR | 1 |
| Weterings, MA | 1 |
| Brown, J | 2 |
| Chittenden, BG | 1 |
| Dallas, S | 1 |
| Jack, SA | 1 |
| Gupta, J | 1 |
| Kai, J | 1 |
| Middleton, L | 1 |
| Pattison, H | 1 |
| Gray, R | 1 |
| Daniels, J | 1 |
| Mercorio, F | 1 |
| De Simone, R | 1 |
| Di Carlo, C | 1 |
| Bifulco, G | 1 |
| Tessitore, G | 1 |
| Di Spiezio Sardo, A | 1 |
| Nappi, C | 1 |
| Reid, PC | 1 |
| Virtanen-Kari, S | 1 |
| Fraser, IS | 5 |
| McCarron, G | 4 |
| Markham, R | 4 |
| Robinson, M | 1 |
| Smyth, E | 1 |
| Vairojanavong, K | 1 |
| Limchitti, D | 1 |
| Sasivimolkul, V | 1 |
| Pearse, C | 1 |
| Shearman, RP | 1 |
| Elliott, PM | 1 |
| McIlveen, J | 1 |
| Duncan, KM | 1 |
| Hart, LL | 1 |
| Bonnar, J | 2 |
| Sheppard, BL | 2 |
| Duckitt, K | 1 |
| Shaw, RW | 1 |
| Ghosh, AK | 1 |
| Fender, GR | 1 |
| Prentice, A | 1 |
| Gorst, T | 1 |
| Nixon, RM | 1 |
| Duffy, SW | 1 |
| Day, NE | 1 |
| Smith, SK | 2 |
| Hope, S | 1 |
| Turner, E | 1 |
| Bowie, P | 1 |
| McMullen, KW | 1 |
| Kellock, C | 1 |
| Anderson, AB | 1 |
| Haynes, PJ | 1 |
| Guillebaud, J | 1 |
| Turnbull, AC | 1 |
| van Eijkeren, MA | 1 |
| Christiaens, GC | 1 |
| Geuze, HJ | 1 |
| Haspels, AA | 1 |
| Sixma, JJ | 1 |
| Chamberlain, G | 1 |
| Freeman, R | 1 |
| Price, F | 1 |
| Kennedy, A | 1 |
| Green, D | 1 |
| Eve, L | 1 |
| Grover, V | 1 |
| Usha, R | 1 |
| Gupta, U | 1 |
| Kalra, S | 1 |
| Cameron, IT | 2 |
| Haining, R | 1 |
| Lumsden, MA | 1 |
| Thomas, VR | 1 |
| Dockeray, CJ | 1 |
| Boyd, ME | 1 |
| Tsang, BK | 1 |
| Domingo, MT | 1 |
| Spence, JE | 1 |
| Garner, PR | 1 |
| Dudley, DK | 1 |
| Oxorn, H | 1 |
| Hall, P | 1 |
| Maclachlan, N | 1 |
| Thorn, N | 1 |
| Nudd, MW | 1 |
| Taylor, CG | 1 |
| Garrioch, DB | 1 |
| Leask, R | 1 |
| Kelly, RW | 1 |
| Baird, DT | 1 |
| Resta, T | 1 |
| Watts, A | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Peroperative Tranexamic Acid as Prophylaxis of Haemorrhage in Benign Hysterectomy - a Randomized, Placebo-controlled Trial[NCT01940419] | Phase 4 | 332 participants (Actual) | Interventional | 2013-04-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
7 reviews available for mefenamic acid and Menorrhagia
| Article | Year |
|---|---|
Interventions to prevent or treat heavy menstrual bleeding or pain associated with intrauterine-device use.
Topics: Acetaminophen; Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Dysmenorrhea; Female; Hum | 2022 |
Progestogen-releasing intrauterine systems for heavy menstrual bleeding.
Topics: Antifibrinolytic Agents; Contraceptives, Oral; Endometrium; Female; Humans; Hysterectomy; Intrauteri | 2020 |
Interventions commonly available during pandemics for heavy menstrual bleeding: an overview of Cochrane Reviews.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antifibrinolytic Agents; Contraceptives, Oral, Hormonal; Fe | 2020 |
Combined hormonal contraceptives for heavy menstrual bleeding.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Contraceptive Agents, Female; Contraceptives, Oral, Combine | 2019 |
Oral contraceptive pill for heavy menstrual bleeding.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Contraceptives, Oral; Danazol; Drug Therapy, Combination; F | 2009 |
Nonsteroidal antiinflammatory drugs in menorrhagia.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Clinical Trials as Topic; Danazol; Female; Humans; I | 1993 |
Menorrhagia.
Topics: Adolescent; Adult; Child; Contraceptives, Oral, Combined; Danazol; Endometrium; Female; Gynecologic | 1998 |
18 trials available for mefenamic acid and Menorrhagia
| Article | Year |
|---|---|
Levonorgestrel intrauterine system versus medical therapy for menorrhagia.
Topics: Adult; Antifibrinolytic Agents; Contraceptive Agents, Female; Estrogens; Female; Follow-Up Studies; | 2013 |
Effectiveness and mechanism of action of desmopressin in the treatment of copper intrauterine device-related menorrhagia: a pilot study.
Topics: Adult; Cyclooxygenase Inhibitors; Deamino Arginine Vasopressin; Female; Hemostatics; Humans; Intraut | 2003 |
Randomised comparative trial of the levonorgestrel intrauterine system and mefenamic acid for the treatment of idiopathic menorrhagia: a multiple analysis using total menstrual fluid loss, menstrual blood loss and pictorial blood loss assessment charts.
Topics: Adolescent; Adult; Analysis of Variance; Anti-Inflammatory Agents, Non-Steroidal; Contraceptive Agen | 2005 |
Long-term treatment of menorrhagia with mefenamic acid.
Topics: Clinical Trials as Topic; Double-Blind Method; Female; Humans; Mefenamic Acid; Menorrhagia; Time Fac | 1983 |
Clinical trial of the efficacy of mefenamic acid in relief of menorrhagia and/or dysmenorrhoea.
Topics: Adolescent; Adult; Clinical Trials as Topic; Dysmenorrhea; Female; Humans; Mefenamic Acid; Menorrhag | 1983 |
A preliminary study of factors influencing perception of menstrual blood loss volume.
Topics: Adult; Age Factors; Clinical Trials as Topic; Double-Blind Method; Dysmenorrhea; Female; Humans; Mef | 1984 |
Efficacy of mefenamic acid in patients with a complaint of menorrhagia.
Topics: Adolescent; Adult; Blood Chemical Analysis; Clinical Trials as Topic; Double-Blind Method; Dysmenorr | 1981 |
Treatment of menorrhagia during menstruation: randomised controlled trial of ethamsylate, mefenamic acid, and tranexamic acid.
Topics: Adult; Antifibrinolytic Agents; Cyclooxygenase Inhibitors; Ethamsylate; Female; Hemostatics; Humans; | 1996 |
Randomised controlled trial of educational package on management of menorrhagia in primary care: the Anglia menorrhagia education study.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antifibrinolytic Agents; Clinical Competence; Decision Maki | 1999 |
Effects of mefenamic acid on menstrual hemostasis in essential menorrhagia.
Topics: Adult; Arterioles; Endometrium; Female; Hemostasis; Humans; Mefenamic Acid; Menorrhagia; Microscopy, | 1992 |
Randomized trial of 2 hormonal and 2 prostaglandin-inhibiting agents in women with a complaint of menorrhagia.
Topics: Contraceptives, Oral, Combined; Danazol; Drug Therapy, Combination; Female; Humans; Mefenamic Acid; | 1991 |
A comparative study of ethamsylate and mefenamic acid in dysfunctional uterine bleeding.
Topics: Adolescent; Adult; Ethamsylate; Female; Humans; Mefenamic Acid; Menorrhagia; Middle Aged | 1991 |
Management of cyclical menorrhagia with prostaglandin synthetase inhibitor.
Topics: Adult; Double-Blind Method; Female; Humans; Mefenamic Acid; Menorrhagia; Menstruation; Middle Aged; | 1990 |
The effects of mefenamic acid and norethisterone on measured menstrual blood loss.
Topics: Adult; Female; Humans; Mefenamic Acid; Menorrhagia; Menstruation; Middle Aged; Norethindrone | 1990 |
Comparison between mefenamic acid and danazol in the treatment of established menorrhagia.
Topics: Adult; Danazol; Female; Humans; Mefenamic Acid; Menorrhagia; Middle Aged; Patient Compliance; Pregna | 1989 |
Endometrial prostaglandins and menorrhagia: influence of a prostaglandin synthetase inhibitor in vivo.
Topics: Adult; Cyclooxygenase Inhibitors; Endometrium; Female; Humans; Mefenamic Acid; Menorrhagia; Menstrua | 1987 |
Control of menorrhagia by the cyclo-oxygenase inhibitors naproxen sodium and mefenamic acid.
Topics: Adolescent; Adult; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Mefenamic Acid; Me | 1987 |
The effects of danazol, mefenamic acid, norethisterone and a progesterone-impregnated coil on endometrial prostaglandin concentrations in women with menorrhagia.
Topics: Biopsy; Danazol; Endometrium; Female; Humans; Intrauterine Devices, Medicated; Mefenamic Acid; Menor | 1987 |
7 other studies available for mefenamic acid and Menorrhagia
| Article | Year |
|---|---|
Trends in the surgical options for the treatment of menorrhagia in Scotland: examination of health episode statistics, 2000-2008.
Topics: Adult; Catheter Ablation; Endometrium; Female; Hormone Replacement Therapy; Humans; Hysterectomy; La | 2012 |
Is medical management of menorrhagia obsolete?
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Estrogen Replacement Therapy; Female; Humans; Hyster | 1998 |
10 minute consultation: menorrhagia.
Topics: Anemia, Iron-Deficiency; Anti-Inflammatory Agents, Non-Steroidal; Antifibrinolytic Agents; Clinical | 2000 |
First-line management of menorrhagia: findings from a survey of general practitioners in Forth Valley.
Topics: Data Collection; Family Practice; Female; Health Care Surveys; Humans; Mefenamic Acid; Menorrhagia; | 2000 |
Reduction of menstrual blood-loss by prostaglandin-synthetase inhibitors.
Topics: Adult; Blood Specimen Collection; Cyclooxygenase Inhibitors; Female; Follow-Up Studies; Humans; Intr | 1976 |
Dysfunctional uterine bleeding.
Topics: Adult; Contraceptives, Oral; Cyclooxygenase Inhibitors; Dilatation and Curettage; Dinoprost; Dinopro | 1986 |
Measured menstrual blood loss in women with menorrhagia associated with pelvic disease or coagulation disorder.
Topics: Blood Coagulation Disorders; Endometriosis; Female; Humans; Mefenamic Acid; Menorrhagia; Menstruatio | 1986 |