mefenamic acid has been researched along with Kidney Papillary Necrosis in 6 studies
Mefenamic Acid: A non-steroidal anti-inflammatory agent with analgesic, anti-inflammatory, and antipyretic properties. It is an inhibitor of cyclooxygenase.
mefenamic acid : An aminobenzoic acid that is anthranilic acid in which one of the hydrogens attached to the nitrogen is replaced by a 2,3-dimethylphenyl group. Although classed as a non-steroidal anti-inflammatory drug, its anti-inflammatory properties are considered to be minor. It is used to relieve mild to moderate pain, including headaches, dental pain, osteoarthritis and rheumatoid arthritis.
Kidney Papillary Necrosis: A complication of kidney diseases characterized by cell death involving KIDNEY PAPILLA in the KIDNEY MEDULLA. Damages to this area may hinder the kidney to concentrate urine resulting in POLYURIA. Sloughed off necrotic tissue may block KIDNEY PELVIS or URETER. Necrosis of multiple renal papillae can lead to KIDNEY FAILURE.
| Excerpt | Relevance | Reference |
|---|---|---|
| "These duodenal ulcers were also prevented by dmPGE2." | 1.27 | Effect of 16,16-dimethyl PGE2 on renal papillary necrosis and gastrointestinal ulcerations (gastric, duodenal, intestinal) produced in rats by mefenamic acid. ( Davis, JP; Elliott, G; Field, SO; Lancaster, C; Purmalis, A; Robert, A; Whited, BA, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (66.67) | 18.7374 |
| 1990's | 1 (16.67) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Nguyen, TK | 1 |
| Obatomi, DK | 1 |
| Bach, PH | 1 |
| Champion de Crespigny, P | 1 |
| Hewitson, T | 1 |
| Birchall, I | 1 |
| Kincaid-Smith, P | 2 |
| Carlton, WW | 1 |
| Engelhardt, JA | 1 |
| Segasothy, M | 1 |
| Thyaparan, A | 1 |
| Kamal, A | 1 |
| Sivalingam, S | 1 |
| Elliott, G | 1 |
| Whited, BA | 1 |
| Purmalis, A | 1 |
| Davis, JP | 1 |
| Field, SO | 1 |
| Lancaster, C | 1 |
| Robert, A | 1 |
| Nanra, RS | 1 |
1 review available for mefenamic acid and Kidney Papillary Necrosis
| Article | Year |
|---|---|
Chronic effect of analgesics on the kidney.
Topics: Aminopyrine; Analgesics; Animals; Antipyrine; Aspirin; Caffeine; Chronic Disease; Drug Combinations; | 1972 |
5 other studies available for mefenamic acid and Kidney Papillary Necrosis
| Article | Year |
|---|---|
Increased urinary uronic acid excretion in experimentally-induced renal papillary necrosis in rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Biomarkers; Creatinine; Kidney Papillary Necrosis; | 2001 |
Caffeine potentiates the nephrotoxicity of mefenamic acid on the rat renal papilla.
Topics: Animals; Caffeine; Drug Synergism; Female; Kidney Medulla; Kidney Papillary Necrosis; Mefenamic Acid | 1990 |
Experimental renal papillary necrosis in the Syrian hamster.
Topics: Acetaminophen; Animals; Cricetinae; Disease Models, Animal; Ethylamines; Indomethacin; Kidney Medull | 1989 |
Mefenamic acid nephropathy.
Topics: Arthritis; Female; Gout; Humans; Kidney Papillary Necrosis; Male; Mefenamic Acid; Middle Aged; Osteo | 1987 |
Effect of 16,16-dimethyl PGE2 on renal papillary necrosis and gastrointestinal ulcerations (gastric, duodenal, intestinal) produced in rats by mefenamic acid.
Topics: 16,16-Dimethylprostaglandin E2; Animals; Duodenal Ulcer; Female; Intestinal Diseases; Kidney Papilla | 1986 |