mefenamic acid has been researched along with Diaper Rash in 1 studies
Mefenamic Acid: A non-steroidal anti-inflammatory agent with analgesic, anti-inflammatory, and antipyretic properties. It is an inhibitor of cyclooxygenase.
mefenamic acid : An aminobenzoic acid that is anthranilic acid in which one of the hydrogens attached to the nitrogen is replaced by a 2,3-dimethylphenyl group. Although classed as a non-steroidal anti-inflammatory drug, its anti-inflammatory properties are considered to be minor. It is used to relieve mild to moderate pain, including headaches, dental pain, osteoarthritis and rheumatoid arthritis.
Diaper Rash: A type of irritant dermatitis localized to the area in contact with a diaper and occurring most often as a reaction to prolonged contact with urine, feces, or retained soap or detergent.
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 1 (100.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Sullivan, RW | 1 |
Ryzewski, M | 1 |
Holland, MG | 1 |
Marraffa, JM | 1 |
Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
---|---|---|---|---|---|---|---|
Antipruritic Effect of Topical Ketamine, Amitriptyline, and Lidocaine[NCT03096444] | Phase 2 | 13 participants (Actual) | Interventional | 2017-05-23 | Terminated (stopped due to Efficacy was not seen after interim analysis) | ||
[information is prepared from clinicaltrials.gov, extracted Sep-2024] |
"Peak itch intensity between the vehicle and 4 other active treatments (individual ketamine, amitriptyline, or lidocaine, and KeAmLi-combo). Itch intensity was measured on a 100mm scale visual analog scale for 10 minutes. 0 was weighted with no itch and 100 was weighted with most itch imaginable." (NCT03096444)
Timeframe: 10 minutes
Intervention | Intensity score (Mean) |
---|---|
Topical KeAmLi Combo | 62.7 |
Topical Ketamine | 63.1 |
Topical Amitriptyline | 69.2 |
Topical Lidocaine | 65.8 |
Topical Vehicle | 61.9 |
Assess mechanical detection and pain thresholds using von Frey filaments stimulators (measured in force mN) to calculate the final threshold as the geometric mean of five series of ascending and descending stimuli. (NCT03096444)
Timeframe: 5 minutes
Intervention | mN (Mean) | |
---|---|---|
Mechanical Detection Threshold | Mechanical Pain Threshold | |
Topical Amitriptyline | 3.573423965 | 152.4768146 |
Topical KeAmLi Combo | 3.519376956 | 152.3293608 |
Topical Ketamine | 3.464204768 | 135.9 |
Topical Lidocaine | 3.546037659 | 126.9 |
Topical Vehicle | 3.525692637 | 148.7138273 |
Two standardized quantitative sensory tests are performed to measure warmth detection threshold (assesses the threshold of which warmth sensation is first detected) and heat pain threshold (assesses the threshold at which heat pain sensation is first detected). Measured in change in celsius. (NCT03096444)
Timeframe: 3 minutes
Intervention | Degrees celsius (Mean) | |
---|---|---|
Warm Detection Threshold | Heat Pain Threshold | |
Topical Amitriptyline | 33.9 | 40.0 |
Topical KeAmLi Combo | 33.6 | 39.8 |
Topical Ketamine | 34.0 | 40.0 |
Topical Lidocaine | 33.7 | 39.4 |
Topical Vehicle | 33.8 | 39.7 |
1 other study available for mefenamic acid and Diaper Rash
Article | Year |
---|---|
Compounded ointment results in severe toxicity in a pediatric patient.
Topics: Administration, Cutaneous; Amines; Analgesics; Body Surface Area; Bradycardia; Clonidine; Combined M | 2013 |