mefenamic acid has been researched along with Asthma in 10 studies
Mefenamic Acid: A non-steroidal anti-inflammatory agent with analgesic, anti-inflammatory, and antipyretic properties. It is an inhibitor of cyclooxygenase.
mefenamic acid : An aminobenzoic acid that is anthranilic acid in which one of the hydrogens attached to the nitrogen is replaced by a 2,3-dimethylphenyl group. Although classed as a non-steroidal anti-inflammatory drug, its anti-inflammatory properties are considered to be minor. It is used to relieve mild to moderate pain, including headaches, dental pain, osteoarthritis and rheumatoid arthritis.
Asthma: A form of bronchial disorder with three distinct components: airway hyper-responsiveness (RESPIRATORY HYPERSENSITIVITY), airway INFLAMMATION, and intermittent AIRWAY OBSTRUCTION. It is characterized by spasmodic contraction of airway smooth muscle, WHEEZING, and dyspnea (DYSPNEA, PAROXYSMAL).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Eleven patients with asthma and aspirin hypersensitivity have been challenged with eight non-steroidal anti-inflammatory drugs." | 7.65 | Relationship of inhibition of prostaglandin biosynthesis by analgesics to asthma attacks in aspirin-sensitive patients. ( Czerniawska-Mysik, G; Gryglewski, RJ; Szczeklik, A, 1975) |
| " In a second case report we describe, in a 61-year-old patient suffering from aspirin-sensitive asthma, recurrent ciliary body oedema with a marked spastic component which was triggered by the medications acetazolamide, dipivefrine and pilocarpine." | 3.69 | Drug-induced ciliary body oedema: a new theory. ( Krieg, PH; Schipper, I, 1996) |
| "Eleven patients with asthma and aspirin hypersensitivity have been challenged with eight non-steroidal anti-inflammatory drugs." | 3.65 | Relationship of inhibition of prostaglandin biosynthesis by analgesics to asthma attacks in aspirin-sensitive patients. ( Czerniawska-Mysik, G; Gryglewski, RJ; Szczeklik, A, 1975) |
| "Challenge tests with some analgesics in common use were performed in five aspirin-sensitive asthmatics." | 3.65 | Response of aspirin-allergic patients to challenge by some analgesics in common use. ( Smith, AP, 1971) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (80.00) | 18.7374 |
| 1990's | 2 (20.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Krieg, PH | 1 |
| Schipper, I | 1 |
| Leynadier, F | 1 |
| Perrault, M | 1 |
| Kordansky, D | 1 |
| Adkinson, NF | 1 |
| Norman, PS | 1 |
| Rosenthal, RR | 1 |
| Szczeklik, A | 2 |
| Gryglewski, RJ | 2 |
| Nizankowska, E | 1 |
| Czerniawska-Mysik, G | 1 |
| Williams, WR | 1 |
| Pawlowicz, A | 1 |
| Davies, BH | 1 |
| Morales, MC | 1 |
| Basomba, A | 1 |
| Villalmanzo, IG | 1 |
| Peláez, A | 1 |
| Campos, A | 1 |
| Guerrero, M | 1 |
| Smith, AP | 1 |
| Jackson, RH | 1 |
| Raymer, WJ | 1 |
| Etter, RL | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Challenge Test for Acetylsalicylic Acid Hypersensitivity[NCT01681615] | 50 participants (Anticipated) | Interventional | 2012-09-30 | Not yet recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for mefenamic acid and Asthma
| Article | Year |
|---|---|
Asthma improved by nonsteroidal anti-inflammatory drugs.
Topics: Airway Resistance; Anti-Inflammatory Agents; Aspirin; Asthma; Clinical Trials as Topic; Female; Forc | 1978 |
9 other studies available for mefenamic acid and Asthma
| Article | Year |
|---|---|
Discussion on the pharmacology of the fenamates.
Topics: Abnormalities, Drug-Induced; Analgesia; Animals; Anti-Inflammatory Agents; Arthritis, Rheumatoid; As | 1966 |
Drug-induced ciliary body oedema: a new theory.
Topics: Acetazolamide; Adult; Asthma; Chlorthalidone; Ciliary Body; Diuretics; Edema; Epinephrine; Female; H | 1996 |
[Anti-inflammatory agents in current therapeutics].
Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Anti-Inflammatory Agents; Arthritis, Rheumatoi | 1975 |
Asthma relieved by aspirin and by other cyclo-oxygenase inhibitors.
Topics: Aspirin; Asthma; Fenoprofen; Humans; Indomethacin; Male; Mefenamic Acid; Middle Aged | 1978 |
Relationship of inhibition of prostaglandin biosynthesis by analgesics to asthma attacks in aspirin-sensitive patients.
Topics: Adult; Aged; Analgesics; Aspirin; Asthma; Bronchi; Drug Hypersensitivity; Female; Flufenamic Acid; H | 1975 |
Aspirin-sensitive asthma: significance of the cyclooxygenase-inhibiting and protein-binding properties of analgesic drugs.
Topics: Acetaminophen; Administration, Inhalation; Adult; Aged; Aspirin; Asthma; Dinoprost; Drug Tolerance; | 1991 |
Crossed tolerance to pyrazolines, mephenamic acid, and glafenine in A. S. A.-triad patients desensitized to aspirin.
Topics: Aspirin; Asthma; Cross Reactions; Desensitization, Immunologic; Drug Tolerance; Female; Glafenine; H | 1985 |
Response of aspirin-allergic patients to challenge by some analgesics in common use.
Topics: Acetaminophen; Adult; Analgesics; Aspirin; Asthma; Dextropropoxyphene; Drug Hypersensitivity; Female | 1971 |
New therapy in bronchial asthma. An evaluation of ponstel (mefenamic acid) in chronic bronchial asthma and pulmonary emphysema.
Topics: Adult; Aged; Anti-Inflammatory Agents; Asthma; Female; Humans; Male; Mefenamic Acid; Middle Aged; or | 1968 |