Page last updated: 2024-10-30

mefenamic acid and Asthma

mefenamic acid has been researched along with Asthma in 10 studies

Mefenamic Acid: A non-steroidal anti-inflammatory agent with analgesic, anti-inflammatory, and antipyretic properties. It is an inhibitor of cyclooxygenase.
mefenamic acid : An aminobenzoic acid that is anthranilic acid in which one of the hydrogens attached to the nitrogen is replaced by a 2,3-dimethylphenyl group. Although classed as a non-steroidal anti-inflammatory drug, its anti-inflammatory properties are considered to be minor. It is used to relieve mild to moderate pain, including headaches, dental pain, osteoarthritis and rheumatoid arthritis.

Asthma: A form of bronchial disorder with three distinct components: airway hyper-responsiveness (RESPIRATORY HYPERSENSITIVITY), airway INFLAMMATION, and intermittent AIRWAY OBSTRUCTION. It is characterized by spasmodic contraction of airway smooth muscle, WHEEZING, and dyspnea (DYSPNEA, PAROXYSMAL).

Research Excerpts

ExcerptRelevanceReference
"Eleven patients with asthma and aspirin hypersensitivity have been challenged with eight non-steroidal anti-inflammatory drugs."7.65Relationship of inhibition of prostaglandin biosynthesis by analgesics to asthma attacks in aspirin-sensitive patients. ( Czerniawska-Mysik, G; Gryglewski, RJ; Szczeklik, A, 1975)
" In a second case report we describe, in a 61-year-old patient suffering from aspirin-sensitive asthma, recurrent ciliary body oedema with a marked spastic component which was triggered by the medications acetazolamide, dipivefrine and pilocarpine."3.69Drug-induced ciliary body oedema: a new theory. ( Krieg, PH; Schipper, I, 1996)
"Eleven patients with asthma and aspirin hypersensitivity have been challenged with eight non-steroidal anti-inflammatory drugs."3.65Relationship of inhibition of prostaglandin biosynthesis by analgesics to asthma attacks in aspirin-sensitive patients. ( Czerniawska-Mysik, G; Gryglewski, RJ; Szczeklik, A, 1975)
"Challenge tests with some analgesics in common use were performed in five aspirin-sensitive asthmatics."3.65Response of aspirin-allergic patients to challenge by some analgesics in common use. ( Smith, AP, 1971)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19908 (80.00)18.7374
1990's2 (20.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Krieg, PH1
Schipper, I1
Leynadier, F1
Perrault, M1
Kordansky, D1
Adkinson, NF1
Norman, PS1
Rosenthal, RR1
Szczeklik, A2
Gryglewski, RJ2
Nizankowska, E1
Czerniawska-Mysik, G1
Williams, WR1
Pawlowicz, A1
Davies, BH1
Morales, MC1
Basomba, A1
Villalmanzo, IG1
Peláez, A1
Campos, A1
Guerrero, M1
Smith, AP1
Jackson, RH1
Raymer, WJ1
Etter, RL1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Challenge Test for Acetylsalicylic Acid Hypersensitivity[NCT01681615]50 participants (Anticipated)Interventional2012-09-30Not yet recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

1 trial available for mefenamic acid and Asthma

ArticleYear
Asthma improved by nonsteroidal anti-inflammatory drugs.
    Annals of internal medicine, 1978, Volume: 88, Issue:4

    Topics: Airway Resistance; Anti-Inflammatory Agents; Aspirin; Asthma; Clinical Trials as Topic; Female; Forc

1978

Other Studies

9 other studies available for mefenamic acid and Asthma

ArticleYear
Discussion on the pharmacology of the fenamates.
    Annals of physical medicine, 1966, Volume: Suppl

    Topics: Abnormalities, Drug-Induced; Analgesia; Animals; Anti-Inflammatory Agents; Arthritis, Rheumatoid; As

1966
Drug-induced ciliary body oedema: a new theory.
    Eye (London, England), 1996, Volume: 10 ( Pt 1)

    Topics: Acetazolamide; Adult; Asthma; Chlorthalidone; Ciliary Body; Diuretics; Edema; Epinephrine; Female; H

1996
[Anti-inflammatory agents in current therapeutics].
    La Revue du praticien, 1975, Jan-21, Volume: 25, Issue:5

    Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Anti-Inflammatory Agents; Arthritis, Rheumatoi

1975
Asthma relieved by aspirin and by other cyclo-oxygenase inhibitors.
    Thorax, 1978, Volume: 33, Issue:5

    Topics: Aspirin; Asthma; Fenoprofen; Humans; Indomethacin; Male; Mefenamic Acid; Middle Aged

1978
Relationship of inhibition of prostaglandin biosynthesis by analgesics to asthma attacks in aspirin-sensitive patients.
    British medical journal, 1975, Jan-11, Volume: 1, Issue:5949

    Topics: Adult; Aged; Analgesics; Aspirin; Asthma; Bronchi; Drug Hypersensitivity; Female; Flufenamic Acid; H

1975
Aspirin-sensitive asthma: significance of the cyclooxygenase-inhibiting and protein-binding properties of analgesic drugs.
    International archives of allergy and applied immunology, 1991, Volume: 95, Issue:4

    Topics: Acetaminophen; Administration, Inhalation; Adult; Aged; Aspirin; Asthma; Dinoprost; Drug Tolerance;

1991
Crossed tolerance to pyrazolines, mephenamic acid, and glafenine in A. S. A.-triad patients desensitized to aspirin.
    The Journal of allergy and clinical immunology, 1985, Volume: 75, Issue:4

    Topics: Aspirin; Asthma; Cross Reactions; Desensitization, Immunologic; Drug Tolerance; Female; Glafenine; H

1985
Response of aspirin-allergic patients to challenge by some analgesics in common use.
    British medical journal, 1971, May-29, Volume: 2, Issue:5760

    Topics: Acetaminophen; Adult; Analgesics; Aspirin; Asthma; Dextropropoxyphene; Drug Hypersensitivity; Female

1971
New therapy in bronchial asthma. An evaluation of ponstel (mefenamic acid) in chronic bronchial asthma and pulmonary emphysema.
    The Journal of the Kansas Medical Society, 1968, Volume: 69, Issue:10

    Topics: Adult; Aged; Anti-Inflammatory Agents; Asthma; Female; Humans; Male; Mefenamic Acid; Middle Aged; or

1968