mefenamic acid has been researched along with Arthritis, Rheumatoid in 40 studies
Mefenamic Acid: A non-steroidal anti-inflammatory agent with analgesic, anti-inflammatory, and antipyretic properties. It is an inhibitor of cyclooxygenase.
mefenamic acid : An aminobenzoic acid that is anthranilic acid in which one of the hydrogens attached to the nitrogen is replaced by a 2,3-dimethylphenyl group. Although classed as a non-steroidal anti-inflammatory drug, its anti-inflammatory properties are considered to be minor. It is used to relieve mild to moderate pain, including headaches, dental pain, osteoarthritis and rheumatoid arthritis.
Arthritis, Rheumatoid: A chronic systemic disease, primarily of the joints, marked by inflammatory changes in the synovial membranes and articular structures, widespread fibrinoid degeneration of the collagen fibers in mesenchymal tissues, and by atrophy and rarefaction of bony structures. Etiology is unknown, but autoimmune mechanisms have been implicated.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A randomized double-blind within-patient study of mefenamic acid compared with ibuprofen was performed on forty patients with rheumatoid arthritis." | 9.04 | Mefenamic acid compared with ibuprofen in the treatment of rheumatoid arthritis. ( Leslie, RD, 1977) |
| "This paper reports a double-blind crossover trial comparing mefenamic acid (1500 mg/day) with ibuprofen (1200 mg/day) in the treatment of patients with rheumatoid arthritis receiving maintenance salicylate therapy." | 9.04 | Comparison of effectiveness of mefenamic acid and ibuprofen in treatment of rheumatoid arthritis. ( Muirden, KD; Stockman, A; Varigos, GA, 1976) |
| "A double-blind crossover study was carried out in 18 patients with classical rheumatoid arthritis to assess the effectiveness of mefenamic acid (500 mg t." | 5.04 | Mefenamic acid: an under-rated antirheumatic? ( Buchanan, WW; Hernandez, LA; MacLeod, M; Mavrikakis, ME; Rennie, JA, 1977) |
| "A randomized double-blind within-patient study of mefenamic acid compared with ibuprofen was performed on forty patients with rheumatoid arthritis." | 5.04 | Mefenamic acid compared with ibuprofen in the treatment of rheumatoid arthritis. ( Leslie, RD, 1977) |
| "This paper reports a double-blind crossover trial comparing mefenamic acid (1500 mg/day) with ibuprofen (1200 mg/day) in the treatment of patients with rheumatoid arthritis receiving maintenance salicylate therapy." | 5.04 | Comparison of effectiveness of mefenamic acid and ibuprofen in treatment of rheumatoid arthritis. ( Muirden, KD; Stockman, A; Varigos, GA, 1976) |
| "Three patients developed autoimmune haemolytic anaemia while being treated with mefenamic acid." | 1.25 | Autoimmune haemolytic anaemia and mefenamic acid therapy. ( Bacon, PA; Myles, AB; Scott, GL, 1968) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 38 (95.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (5.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, YR | 1 |
| Hsieh, FI | 1 |
| Chang, CC | 1 |
| Chi, NF | 1 |
| Wu, HC | 1 |
| Chiou, HY | 1 |
| Patel, P | 1 |
| Madan, P | 1 |
| Lin, S | 1 |
| CAHILL, WJ | 1 |
| HILL, RD | 1 |
| JESSOP, J | 1 |
| KENDALL, PH | 1 |
| Mason, RM | 1 |
| Barnardo, DE | 1 |
| Fox, WR | 1 |
| Weatherall, M | 2 |
| Simon, LS | 1 |
| Mills, JA | 1 |
| Lee, P | 2 |
| Anderson, JA | 2 |
| Miller, J | 2 |
| Webb, J | 2 |
| Buchanan, WW | 6 |
| Huskisson, EC | 1 |
| Leynadier, F | 1 |
| Perrault, M | 1 |
| Mavrikakis, ME | 2 |
| Madkour, MM | 1 |
| MacLeod, M | 1 |
| Hernandez, LA | 1 |
| Rennie, JA | 1 |
| Leslie, RD | 1 |
| Reinicke, C | 1 |
| Stephens, WH | 1 |
| El-Ghobarey, AF | 1 |
| Macleod, MM | 1 |
| Trinus, FP | 1 |
| Mokhort, NA | 1 |
| Farquet, JJ | 1 |
| Dayer, JM | 1 |
| Miescher, PA | 1 |
| Dormidontov, EN | 1 |
| Korshunov, NI | 1 |
| Baranova, EIa | 1 |
| Stockman, A | 1 |
| Varigos, GA | 1 |
| Muirden, KD | 1 |
| Wax, J | 1 |
| Tessman, DK | 1 |
| Winder, CV | 1 |
| Stephens, MD | 1 |
| Juby, LD | 1 |
| Axon, AT | 1 |
| Wright, V | 1 |
| Winstanley, P | 1 |
| Rothwell, J | 1 |
| Myles, AB | 2 |
| Bacon, PA | 2 |
| Williams, KA | 1 |
| Cosh, JA | 1 |
| Martel, RR | 1 |
| Klicius, J | 1 |
| Herr, F | 1 |
| Wawrzyńska-Pagowska, J | 1 |
| Jeremy, R | 1 |
| Cardoe, N | 1 |
| Dick, WC | 1 |
| Porro, A | 1 |
| Schmied, P | 1 |
| Van Rossum, P | 1 |
| Fallet, GH | 1 |
| Rau, R | 1 |
| Camus, JP | 1 |
| Jackson, JM | 1 |
| Quinlan, J | 1 |
| Goatcher, P | 1 |
| Böni, A | 1 |
| Lockie, LM | 1 |
| Kater, RM | 1 |
| Scott, GL | 1 |
8 reviews available for mefenamic acid and Arthritis, Rheumatoid
| Article | Year |
|---|---|
Nonsteroidal antiinflammatory drugs (second of two parts).
Topics: Anti-Inflammatory Agents; Arthritis; Arthritis, Rheumatoid; Fenoprofen; Humans; Ibuprofen; Mefenamic | 1980 |
Antiinflammatory drugs.
Topics: Adult; Anti-Inflammatory Agents; Apazone; Arthritis, Rheumatoid; Aspirin; Benzylidene Compounds; Chi | 1977 |
[Nonsteroid antirheumatic agents].
Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Fenoprofen; Flufenamic Acid; Humans; Indomethacin; | 1977 |
[Pharmacological and clinical aspects of mefenamic acid--nonsteroid anti-inflammatory drug (review of the literature)].
Topics: Animals; Arthritis, Rheumatoid; Humans; Hypersensitivity; Mefenamic Acid; Myocarditis; Rheumatic Dis | 1979 |
[Clinical use of non-steroid anti-inflammatory agents].
Topics: Animals; Anti-Inflammatory Agents; Antigen-Antibody Complex; Arthritis, Rheumatoid; Aspirin; Cell Mi | 1974 |
A critical appraisal of therapy in rheumatoid arthritis.
Topics: Anti-Inflammatory Agents; Antimalarials; Antimetabolites; Arthritis, Rheumatoid; Aspirin; Flufenamic | 1968 |
Advances in the treatment of rheumatic disorders.
Topics: Acetaminophen; Analgesics; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Chloroquine; Female; Flu | 1971 |
[The conservative treatment of chronic inflammatory rheumatism].
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Analgesics; Anti-Inflammatory Agents; Antimalarials; Art | 1969 |
12 trials available for mefenamic acid and Arthritis, Rheumatoid
| Article | Year |
|---|---|
Evaluation of analgesic action and efficacy of antirheumatic drugs. Study of 10 drugs in 684 patients with rheumatoid arthritis.
Topics: Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Aspirin; Clinical Tri | 1976 |
Mefenamic acid: an under-rated antirheumatic?
Topics: Adult; Arthritis, Rheumatoid; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Indomet | 1977 |
Mefenamic acid compared with ibuprofen in the treatment of rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Clinical Trials as Topic; Dose-Response Relationship, Drug; Female; Humans; I | 1977 |
A double-blind, crossover trial of mefenamic acid, sulindac and flurbiprofen in rheumatoid arthritis.
Topics: Adult; Aged; Arthritis, Rheumatoid; Clinical Trials as Topic; Double-Blind Method; Female; Flurbipro | 1979 |
Comparison of effectiveness of mefenamic acid and ibuprofen in treatment of rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Clinical Trials as Topic; Female; Humans; Ibuprofen; Male; Mefenamic Acid; Ph | 1976 |
[Comparative evaluation of the therapeutic efficiency of flurbiprofene in rheumatoid polyarthritis].
Topics: Acetaminophen; Arthritis, Rheumatoid; Aspirin; Biphenyl Compounds; Chemical Phenomena; Chemistry; Cl | 1975 |
Mefenamic acid in rheumatoid arthritis.
Topics: Adrenocorticotropic Hormone; Adult; Aged; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; | 1967 |
Clinical trials of the fenamates. The value of computers in analysing clinical trials.
Topics: Analysis of Variance; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Clinical Trials as Topic; Com | 1966 |
A clinical trial of flufenamic acid in the treatment of rheumatoid arthritis.
Topics: Abdomen, Acute; Acetaminophen; Aluminum; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspartate | 1966 |
[Antipyretic activity of mefenamic acid. Double-blind clinical studies in comparison with amidopyrine and a placebo].
Topics: Adolescent; Aminopyrine; Analgesics; Arthritis, Rheumatoid; Clinical Trials as Topic; Drug Tolerance | 1971 |
Mefenamic acid.
Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Clinical Trials as Topic; Female; Humans; Mefenamic | 1966 |
Double-blind evaluation of the analgesic and toxic effects of flufenamic acid and mefenamic acid in patients with chronic pain.
Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Flufenamic Acid; Fluorine; Humans; Mefenamic Acid; | 1968 |
20 other studies available for mefenamic acid and Arthritis, Rheumatoid
| Article | Year |
|---|---|
Effect on Risk of Stroke and Acute Myocardial Infarction of Nonselective Nonsteroidal Anti-Inflammatory Drugs in Patients With Rheumatoid Arthritis.
Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Celecoxib; | 2018 |
Formulation and evaluation of time-controlled triple-concentric mefenamic acid tablets for rheumatoid arthritis.
Topics: Acrylic Resins; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Delayed-Action Prepa | 2014 |
TRIAL OF MEFENAMIC ACID.
Topics: Analgesics; Analgesics, Non-Narcotic; Antipyretics; Arthritis; Arthritis, Rheumatoid; Bone Neoplasms | 1965 |
Discussion on the pharmacology of the fenamates.
Topics: Abnormalities, Drug-Induced; Analgesia; Animals; Anti-Inflammatory Agents; Arthritis, Rheumatoid; As | 1966 |
Assessment of drugs in out-patients with rheumatoid arthritis. Evaluation of methods and a comparison of mefenamic and flufenamic acids with phenylbutazone and aspirin.
Topics: Acetaminophen; Adult; Agglutination Tests; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; | 1967 |
[Anti-inflammatory agents in current therapeutics].
Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Anti-Inflammatory Agents; Arthritis, Rheumatoi | 1975 |
The place of mefenamic acid in the treatment of rheumatoid arthritis.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Flufenamic Acid; Humans; Mefenamic A | 1978 |
[Autoimmune hemolytic anemia induced by mefenamic acid].
Topics: Anemia, Hemolytic, Autoimmune; Antibodies; Arthritis, Rheumatoid; Erythrocytes; Humans; Immunoglobul | 1978 |
[Antirheumatic non-steroid drugs in the treatment of rheumatoid arthritis].
Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Drug Evaluation; Humans; Ibuprofen; Indome | 1978 |
A sensitive method for the comparative bioassay of nonsteroidal anti-inflammatory compounds in adjuvant-induced primary inflammation in the rat.
Topics: Aminopyrine; Analysis of Variance; Animals; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin | 1975 |
Intestinal permeability and inflammation in rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Humans; Intestine, Small; Mefenamic Acid; Permeability | 1986 |
Anti-inflammatory drugs in rheumatic diseases.
Topics: Adrenocorticotropic Hormone; Anti-Inflammatory Agents; Antimalarials; Arthritis, Rheumatoid; Aspirin | 1974 |
Determination of the therapeutic mean effective doses of several anti-inflammatory agents in adjuvant arthritic rats.
Topics: Aminopyrine; Animals; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Dose-Response Relati | 1974 |
[Drug therapy of progressive chronic polyarthritis].
Topics: Alkylating Agents; Analgesics; Anti-Bacterial Agents; Anti-Inflammatory Agents; Antimalarials; Antim | 1972 |
[The new anti-inflammatory acids. Niflumic acid in rheumatology].
Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Flufenamic Acid; Fluorine; Humans; Mefenamic Acid; | 1968 |
Discussion on clinical trials of the fenamates.
Topics: Analgesia; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Central Nervous System; Flufena | 1966 |
Mefanamic acid-induced haemolytic anaemia.
Topics: Adult; Anemia, Hemolytic, Autoimmune; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Humans; Male; | 1970 |
[Therapy of progressive chronic polyarthritis].
Topics: Arthritis, Rheumatoid; Chronic Disease; Cortisone; Flufenamic Acid; Gold; Humans; Indoles; Mefenamic | 1970 |
Current evaluation of drugs for treating arthritis.
Topics: Acetaminophen; Adrenal Cortex Hormones; Arthritis; Arthritis, Rheumatoid; Aspirin; Chloroquine; Code | 1971 |
Autoimmune haemolytic anaemia and mefenamic acid therapy.
Topics: Anemia, Hemolytic, Autoimmune; Anti-Inflammatory Agents; Antibody Formation; Arthritis, Rheumatoid; | 1968 |