Page last updated: 2024-10-30

mefenamic acid and Allergy, Drug

mefenamic acid has been researched along with Allergy, Drug in 11 studies

Mefenamic Acid: A non-steroidal anti-inflammatory agent with analgesic, anti-inflammatory, and antipyretic properties. It is an inhibitor of cyclooxygenase.
mefenamic acid : An aminobenzoic acid that is anthranilic acid in which one of the hydrogens attached to the nitrogen is replaced by a 2,3-dimethylphenyl group. Although classed as a non-steroidal anti-inflammatory drug, its anti-inflammatory properties are considered to be minor. It is used to relieve mild to moderate pain, including headaches, dental pain, osteoarthritis and rheumatoid arthritis.

Research Excerpts

ExcerptRelevanceReference
"A 65-year-old, previously healthy man developed acute renal failure, severe thrombocytopenia and hepatic icterus after a small dose of mefenamic acid (Parkemed)."7.68Case report: acute renal failure, thrombocytopenia and nonhemolytic icterus probably caused by mefenamic acid (Parkemed)-dependent antibodies. ( Gellner, B; Gremmel, F; Kurz, R; Pausch, V; Schwartz, D; Tragl, KH, 1992)
"Eleven patients with asthma and aspirin hypersensitivity have been challenged with eight non-steroidal anti-inflammatory drugs."7.65Relationship of inhibition of prostaglandin biosynthesis by analgesics to asthma attacks in aspirin-sensitive patients. ( Czerniawska-Mysik, G; Gryglewski, RJ; Szczeklik, A, 1975)
"A 65-year-old, previously healthy man developed acute renal failure, severe thrombocytopenia and hepatic icterus after a small dose of mefenamic acid (Parkemed)."3.68Case report: acute renal failure, thrombocytopenia and nonhemolytic icterus probably caused by mefenamic acid (Parkemed)-dependent antibodies. ( Gellner, B; Gremmel, F; Kurz, R; Pausch, V; Schwartz, D; Tragl, KH, 1992)
"Eleven patients with asthma and aspirin hypersensitivity have been challenged with eight non-steroidal anti-inflammatory drugs."3.65Relationship of inhibition of prostaglandin biosynthesis by analgesics to asthma attacks in aspirin-sensitive patients. ( Czerniawska-Mysik, G; Gryglewski, RJ; Szczeklik, A, 1975)
"Challenge tests with some analgesics in common use were performed in five aspirin-sensitive asthmatics."3.65Response of aspirin-allergic patients to challenge by some analgesics in common use. ( Smith, AP, 1971)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19906 (54.55)18.7374
1990's2 (18.18)18.2507
2000's3 (27.27)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Buylaert, MA1
Schifferli, JA1
Komericki, P1
Arbab, E1
Grims, R1
Kränke, B1
Aberer, W1
Berger, D1
Pichler, W1
Savic, S1
Schoenenberger, R1
Borer, H1
Leynadier, F1
Perrault, M1
Szczeklik, A1
Gryglewski, RJ1
Czerniawska-Mysik, G1
Schwartz, D1
Gremmel, F1
Kurz, R1
Tragl, KH1
Gellner, B1
Pausch, V1
Long, CC1
Finlay, AY1
Marks, R1
Seymour, RA1
Bach, GL1
Worlledge, SM1
Smith, AP1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Challenge Test for Acetylsalicylic Acid Hypersensitivity[NCT01681615]50 participants (Anticipated)Interventional2012-09-30Not yet recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for mefenamic acid and Allergy, Drug

ArticleYear
Immune drug-induced hemolytic anemias.
    Seminars in hematology, 1973, Volume: 10, Issue:4

    Topics: Anemia, Hemolytic; Antibodies; Antigen-Antibody Complex; Antigens; Autoantibodies; Autoimmune Diseas

1973

Other Studies

10 other studies available for mefenamic acid and Allergy, Drug

ArticleYear
[Acute renal failure--"a well meant present from a friend"].
    Therapeutische Umschau. Revue therapeutique, 2004, Volume: 61, Issue:12

    Topics: Acute Kidney Injury; Administration, Cutaneous; Administration, Oral; Aged; Anti-Inflammatory Agents

2004
Tryptase as severity marker in drug provocation tests.
    International archives of allergy and immunology, 2006, Volume: 140, Issue:2

    Topics: Acetaminophen; Adolescent; Adult; Aspirin; Diclofenac; Drug Hypersensitivity; Female; Humans; Lidoca

2006
[Fever, pneumonia and eosinophilia].
    Praxis, 2007, Oct-03, Volume: 96, Issue:40

    Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Bronchoalveolar Lavage Fluid; Diagnosis, Differential

2007
[Anti-inflammatory agents in current therapeutics].
    La Revue du praticien, 1975, Jan-21, Volume: 25, Issue:5

    Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Anti-Inflammatory Agents; Arthritis, Rheumatoi

1975
Relationship of inhibition of prostaglandin biosynthesis by analgesics to asthma attacks in aspirin-sensitive patients.
    British medical journal, 1975, Jan-11, Volume: 1, Issue:5949

    Topics: Adult; Aged; Analgesics; Aspirin; Asthma; Bronchi; Drug Hypersensitivity; Female; Flufenamic Acid; H

1975
Case report: acute renal failure, thrombocytopenia and nonhemolytic icterus probably caused by mefenamic acid (Parkemed)-dependent antibodies.
    Beitrage zur Infusionstherapie = Contributions to infusion therapy, 1992, Volume: 30

    Topics: Acute Kidney Injury; Aged; Antigens, Human Platelet; Anuria; Blood Component Transfusion; Drug Hyper

1992
Fixed drug eruption to mefenamic acid: a report of three cases.
    The British journal of dermatology, 1992, Volume: 126, Issue:4

    Topics: Adult; Drug Hypersensitivity; Dysmenorrhea; Female; Humans; Mefenamic Acid; Middle Aged; Skin Diseas

1992
Prescribing analgesics.
    British dental journal, 1985, Sep-21, Volume: 159, Issue:6

    Topics: Acetaminophen; Aged; Analgesics; Anticoagulants; Aspirin; Child; Codeine; Diflunisal; Drug Hypersens

1985
Adverse reactions of antirheumatic drugs.
    International journal of clinical pharmacology, therapy and toxicology, 1973, Volume: 7, Issue:2

    Topics: Analgesics; Anti-Inflammatory Agents; Chloroquine; Dimethylamines; Drug Hypersensitivity; Gold; Huma

1973
Response of aspirin-allergic patients to challenge by some analgesics in common use.
    British medical journal, 1971, May-29, Volume: 2, Issue:5760

    Topics: Acetaminophen; Adult; Analgesics; Aspirin; Asthma; Dextropropoxyphene; Drug Hypersensitivity; Female

1971