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mefenamic acid and Acute Kidney Injury

mefenamic acid has been researched along with Acute Kidney Injury in 15 studies

Mefenamic Acid: A non-steroidal anti-inflammatory agent with analgesic, anti-inflammatory, and antipyretic properties. It is an inhibitor of cyclooxygenase.
mefenamic acid : An aminobenzoic acid that is anthranilic acid in which one of the hydrogens attached to the nitrogen is replaced by a 2,3-dimethylphenyl group. Although classed as a non-steroidal anti-inflammatory drug, its anti-inflammatory properties are considered to be minor. It is used to relieve mild to moderate pain, including headaches, dental pain, osteoarthritis and rheumatoid arthritis.

Acute Kidney Injury: Abrupt reduction in kidney function. Acute kidney injury encompasses the entire spectrum of the syndrome including acute kidney failure; ACUTE KIDNEY TUBULAR NECROSIS; and other less severe conditions.

Research Excerpts

ExcerptRelevanceReference
"Mefenamic acid ingestion, usually in excess and over prolonged period is known to produce interstitial nephritis, or less commonly papillary necrosis, with acute renal failure."7.71Acute renal failure from hemoglobinuric and interstitial nephritis secondary to iodine and mefenamic acid. ( Lye, WC; Sinniah, R, 2001)
"A 65-year-old, previously healthy man developed acute renal failure, severe thrombocytopenia and hepatic icterus after a small dose of mefenamic acid (Parkemed)."7.68Case report: acute renal failure, thrombocytopenia and nonhemolytic icterus probably caused by mefenamic acid (Parkemed)-dependent antibodies. ( Gellner, B; Gremmel, F; Kurz, R; Pausch, V; Schwartz, D; Tragl, KH, 1992)
"We report mefenamic acid-induced non-oliguric renal failure and severe neutropenia occurring simultaneously in two elderly females."7.68Mefenamic acid-induced neutropenia and renal failure in elderly females with hypothyroidism. ( Freestone, S; Handa, SI, 1990)
"Acute interstitial nephritis is a rare complication of treatment with non-steroidal antiinflammatory drugs."5.27[Mefenamic acid (Ponstan)-induced acute interstitial nephritis with reversible, severe, non-oliguric renal failure]. ( Brunner, K; Burger, HR; Greminger, P; Streuli, R, 1985)
"Mefenamic acid ingestion, usually in excess and over prolonged period is known to produce interstitial nephritis, or less commonly papillary necrosis, with acute renal failure."3.71Acute renal failure from hemoglobinuric and interstitial nephritis secondary to iodine and mefenamic acid. ( Lye, WC; Sinniah, R, 2001)
"A 65-year-old, previously healthy man developed acute renal failure, severe thrombocytopenia and hepatic icterus after a small dose of mefenamic acid (Parkemed)."3.68Case report: acute renal failure, thrombocytopenia and nonhemolytic icterus probably caused by mefenamic acid (Parkemed)-dependent antibodies. ( Gellner, B; Gremmel, F; Kurz, R; Pausch, V; Schwartz, D; Tragl, KH, 1992)
"We report mefenamic acid-induced non-oliguric renal failure and severe neutropenia occurring simultaneously in two elderly females."3.68Mefenamic acid-induced neutropenia and renal failure in elderly females with hypothyroidism. ( Freestone, S; Handa, SI, 1990)
"Acute renal failure is commonly seen in adults after treatment with analgesic agents."1.35Acute, reversible nonoliguric renal failure in two children associated with analgesic-antipyretic drugs. ( Baskin, E; Bayrakci, US; Cengiz, N; Erçoban, HS; Melek, E; Onay, OS, 2009)
" We suggest that the immune complex mechanism could have induced these adverse reactions."1.29Serious adverse effects induced by simultaneous administration of two nonsteroidal anti-inflammatory drugs. ( Awaya, N; Handa, M; Matsuyama, M; Ogino, M; Okada, H; Saruta, T; Suzuki, H; Toya, S, 1993)
"Acute interstitial nephritis is a rare complication of treatment with non-steroidal antiinflammatory drugs."1.27[Mefenamic acid (Ponstan)-induced acute interstitial nephritis with reversible, severe, non-oliguric renal failure]. ( Brunner, K; Burger, HR; Greminger, P; Streuli, R, 1985)

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19907 (46.67)18.7374
1990's4 (26.67)18.2507
2000's4 (26.67)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Onay, OS1
Erçoban, HS1
Bayrakci, US1
Melek, E1
Cengiz, N1
Baskin, E1
Buylaert, MA1
Schifferli, JA1
Künzel, AR1
Haschke, M1
Surber, C1
Lambrecht, JT1
Baker, LR1
Cattell, WR1
Levison, DA1
Edelman, JB1
Drury, PL1
Asirdas, LG1
Bulger, GV1
Abt, AB1
Oh, JY1
Huntington, RA1
Burkhart, KK1
Okada, H1
Suzuki, H1
Awaya, N1
Handa, M1
Ogino, M1
Matsuyama, M1
Toya, S1
Saruta, T1
Sinniah, R1
Lye, WC1
Schwartz, D1
Gremmel, F1
Kurz, R1
Tragl, KH1
Gellner, B1
Pausch, V1
Handa, SI1
Freestone, S1
Turnbull, AJ1
Campbell, P1
Hughes, JA1
Taha, A1
Lenton, RJ1
Murdoch, PS1
Peden, NR1
Poulton, S1
Craft, T1
Severs, M1
Brunner, K1
Burger, HR1
Greminger, P1
Streuli, R1

Reviews

1 review available for mefenamic acid and Acute Kidney Injury

ArticleYear
[Mefenamic acid and other non-steroidal anti-inflammatory agents in dental practice. A review of the literature].
    Schweizer Monatsschrift fur Zahnmedizin = Revue mensuelle suisse d'odonto-stomatologie = Rivista mensile svizzera di odontologia e stomatologia, 2007, Volume: 117, Issue:1

    Topics: Acute Kidney Injury; Anti-Inflammatory Agents, Non-Steroidal; Humans; Mefenamic Acid; Pharmaceutical

2007

Other Studies

14 other studies available for mefenamic acid and Acute Kidney Injury

ArticleYear
Acute, reversible nonoliguric renal failure in two children associated with analgesic-antipyretic drugs.
    Pediatric emergency care, 2009, Volume: 25, Issue:4

    Topics: Abdominal Pain; Acetaminophen; Acute Kidney Injury; Adolescent; Analgesics, Non-Narcotic; Child; Deh

2009
[Acute renal failure--"a well meant present from a friend"].
    Therapeutische Umschau. Revue therapeutique, 2004, Volume: 61, Issue:12

    Topics: Acute Kidney Injury; Administration, Cutaneous; Administration, Oral; Aged; Anti-Inflammatory Agents

2004
Mefenamic acid nephropathy.
    Lancet (London, England), 1980, Oct-04, Volume: 2, Issue:8197

    Topics: Acute Kidney Injury; Adult; Aged; Arthritis; Female; Glomerulonephritis; Humans; Mefenamic Acid; Sci

1980
Mefenamic acid-induced interstitial nephritis and renal failure.
    Postgraduate medical journal, 1984, Volume: 60, Issue:699

    Topics: Acute Kidney Injury; Female; Humans; Mefenamic Acid; Middle Aged; Nephritis, Interstitial

1984
Mefenamic acid nephropathy: further evidence.
    British medical journal (Clinical research ed.), 1981, Mar-14, Volume: 282, Issue:6267

    Topics: Acute Kidney Injury; Creatinine; Female; Humans; Mefenamic Acid; Middle Aged; Time Factors

1981
Chinese herbal medicine induced acute renal failure.
    Archives of internal medicine, 1995, Jan-23, Volume: 155, Issue:2

    Topics: Acute Kidney Injury; Diazepam; Drug Contamination; Drugs, Chinese Herbal; Female; Humans; Mefenamic

1995
Serious adverse effects induced by simultaneous administration of two nonsteroidal anti-inflammatory drugs.
    Southern medical journal, 1993, Volume: 86, Issue:11

    Topics: Acute Kidney Injury; Agranulocytosis; Anemia, Hemolytic; Diclofenac; Drug Therapy, Combination; Fema

1993
Acute renal failure from hemoglobinuric and interstitial nephritis secondary to iodine and mefenamic acid.
    Clinical nephrology, 2001, Volume: 55, Issue:3

    Topics: Acute Disease; Acute Kidney Injury; Adult; Anti-Inflammatory Agents, Non-Steroidal; Hemoglobinuria;

2001
Case report: acute renal failure, thrombocytopenia and nonhemolytic icterus probably caused by mefenamic acid (Parkemed)-dependent antibodies.
    Beitrage zur Infusionstherapie = Contributions to infusion therapy, 1992, Volume: 30

    Topics: Acute Kidney Injury; Aged; Antigens, Human Platelet; Anuria; Blood Component Transfusion; Drug Hyper

1992
Mefenamic acid-induced neutropenia and renal failure in elderly females with hypothyroidism.
    Postgraduate medical journal, 1990, Volume: 66, Issue:777

    Topics: Acute Kidney Injury; Aged; Aged, 80 and over; Analgesia; Female; Humans; Hypothyroidism; Mefenamic A

1990
Mefenamic acid nephropathy--acute renal failure in overdose.
    British medical journal (Clinical research ed.), 1988, Feb-27, Volume: 296, Issue:6622

    Topics: Acute Kidney Injury; Adult; Humans; Male; Mefenamic Acid

1988
Non-oliguric renal failure during treatment with mefenamic acid in elderly patients: a continuing problem.
    British medical journal (Clinical research ed.), 1985, Sep-07, Volume: 291, Issue:6496

    Topics: Acute Kidney Injury; Aged; Female; Humans; Male; Mefenamic Acid

1985
Non-oliguric renal failure during treatment with mefenamic acid in elderly patients.
    British medical journal (Clinical research ed.), 1985, Oct-12, Volume: 291, Issue:6501

    Topics: Acute Kidney Injury; Aged; Female; Humans; Mefenamic Acid

1985
[Mefenamic acid (Ponstan)-induced acute interstitial nephritis with reversible, severe, non-oliguric renal failure].
    Schweizerische medizinische Wochenschrift, 1985, Nov-30, Volume: 115, Issue:48

    Topics: Acute Kidney Injury; Creatinine; Elbow Injuries; Fracture Fixation, Internal; Humans; Male; Mefenami

1985