Page last updated: 2024-10-30

mefenamic acid and Ache

mefenamic acid has been researched along with Ache in 50 studies

Mefenamic Acid: A non-steroidal anti-inflammatory agent with analgesic, anti-inflammatory, and antipyretic properties. It is an inhibitor of cyclooxygenase.
mefenamic acid : An aminobenzoic acid that is anthranilic acid in which one of the hydrogens attached to the nitrogen is replaced by a 2,3-dimethylphenyl group. Although classed as a non-steroidal anti-inflammatory drug, its anti-inflammatory properties are considered to be minor. It is used to relieve mild to moderate pain, including headaches, dental pain, osteoarthritis and rheumatoid arthritis.

Research Excerpts

ExcerptRelevanceReference
"The aim of the study was to compare the effect of mefenamic acid and ginger on pain management in primary dysmenorrhea."9.20The effect of mefenamic acid and ginger on pain relief in primary dysmenorrhea: a randomized clinical trial. ( Alipour, A; Motahari-Tabari, N; Shirvani, MA, 2015)
"To evaluate the efficacy and level of satisfaction from mefenamic acid and hyoscine when used for pain relief during saline infusion sonohysterography."9.15Efficacy of mefenamic acid and hyoscine for pain relief during saline infusion sonohysterography in infertile women: a double blind randomized controlled trial. ( Choavaratana, R; Jareethum, R; Laokirkkiat, P; Petyim, S; Prechapanich, J; Suksompong, S, 2011)
"To compare the efficacy of mefenamic acid vs paracervical block for pain relief during and after fractional curettage."9.11Randomized controlled trial of mefenamic acid vs paracervical block for relief of pain for outpatient uterine curettage. ( Buppasiri, P; Tangmanowutikul, S; Yoosuk, W, 2005)
"Thirty patients suffering from strains, sprains or direct soft tissue injuries were entered into a double-blind trial comparing mefenamic acid and piroxicam."9.06A double-blind comparison of mefenamic acid and piroxicam in acute soft tissue injuries. ( Haig, G, 1988)
"Forty women with moderate to severe primary dysmenorrhea participated in a two-month, double-blind, crossover trial comparing ketoprofen with mefenamic acid."9.06Double-blind comparison of ketoprofen and mefenamic acid in the treatment of primary dysmenorrhea. ( Bourgouin, J; Hébert, JG; Le Morvan, P, 1986)
"A single-blind study was carried out in 52 patients with severe pain after Colles' fracture to assess the analgesic efficacy and tolerability of 500 mg diflunisal twice daily compared with that of 500 mg mefenamic acid given 3-times daily over a period of 5 days."9.05Single-blind study of diflunisal versus mefenamic acid in the treatment of pain after Colles' fracture. ( Barrington, R, 1980)
"A comparison was made between the relative effects of aspirin, mefenamic acid, dihydrocodeine , dextropropoxyphene and paracetamol on visceral pain (chemically-inducing writhing), respiratory rate and prostaglandin (PG) biosynthesis (cyclo-oxygenase activity)."7.67Comparison of the relative effects of aspirin, mefenamic acid, dihydrocodeine, dextropropoxyphene and paracetamol on visceral pain, respiratory rate and prostaglandin biosynthesis. ( Gonzalez, JP; Pugh, J; Sewell, RD, 1984)
"A double-blind three-way crossover design in the treatment of dysmenorrhea comparing a propionic acid derivative (ibuprofen) and a fenamate (mefenamic acid) with a placebo showed that both ibuprofen and mefenamic acid are generally superior to placebo."7.66A double-blind comparison of a propionic acid derivative (ibuprofen) and a fenamate (mefenamic acid) in the treatment of dysmenorrhea. ( Roy, S, 1983)
"The combination of ibuprofen/paracetamol, taken immediately after initial endodontic therapy and root canal preparation in teeth with irreversible pulpitis, reduced post-endodontic pain (ClinicalTrials."5.22Double-blind Randomized Placebo-controlled Clinical Trial of Efficiency of Nonsteroidal Anti-inflammatory Drugs in the Control of Post-endodontic Pain. ( Abubakr, NH; Elzaki, WM; Ibrahim, YE; Ziada, HM, 2016)
"The aim of the study was to compare the effect of mefenamic acid and ginger on pain management in primary dysmenorrhea."5.20The effect of mefenamic acid and ginger on pain relief in primary dysmenorrhea: a randomized clinical trial. ( Alipour, A; Motahari-Tabari, N; Shirvani, MA, 2015)
" To measure anxiety, visual analog anxiety scale was used 90 minutes before starting procedure, individuals in intervention group (n=32) received a single dose (1,500 mg) of 3 Valeric capsules, together with routine prophylaxy, where routine prophylaxis contains Mefenamic acid 250mg capsules in 30 minutes before procedure, and the same capsules were prescribed to placebo group (n=32) with the same instruction."5.20The effect of valeric on anxiety severity in women undergoing hysterosalpingography. ( Bahrani, N; Gharib, M; Kiani, K; Naseri, M; Panah, ZE; Samani, LN, 2015)
"To evaluate the efficacy and level of satisfaction from mefenamic acid and hyoscine when used for pain relief during saline infusion sonohysterography."5.15Efficacy of mefenamic acid and hyoscine for pain relief during saline infusion sonohysterography in infertile women: a double blind randomized controlled trial. ( Choavaratana, R; Jareethum, R; Laokirkkiat, P; Petyim, S; Prechapanich, J; Suksompong, S, 2011)
"To compare the efficacy of mefenamic acid vs paracervical block for pain relief during and after fractional curettage."5.11Randomized controlled trial of mefenamic acid vs paracervical block for relief of pain for outpatient uterine curettage. ( Buppasiri, P; Tangmanowutikul, S; Yoosuk, W, 2005)
"Thirty patients suffering from strains, sprains or direct soft tissue injuries were entered into a double-blind trial comparing mefenamic acid and piroxicam."5.06A double-blind comparison of mefenamic acid and piroxicam in acute soft tissue injuries. ( Haig, G, 1988)
"Forty women with moderate to severe primary dysmenorrhea participated in a two-month, double-blind, crossover trial comparing ketoprofen with mefenamic acid."5.06Double-blind comparison of ketoprofen and mefenamic acid in the treatment of primary dysmenorrhea. ( Bourgouin, J; Hébert, JG; Le Morvan, P, 1986)
"A single-blind study was carried out in 52 patients with severe pain after Colles' fracture to assess the analgesic efficacy and tolerability of 500 mg diflunisal twice daily compared with that of 500 mg mefenamic acid given 3-times daily over a period of 5 days."5.05Single-blind study of diflunisal versus mefenamic acid in the treatment of pain after Colles' fracture. ( Barrington, R, 1980)
"A double-blind study was carried out in 48 patients with soft-tissue injuries to compare the effectiveness of mefenamic acid and dextropropoxyphene plus paracetamol in relieving acute post-injury pain."5.04Mefenamic acid and dextropropoxyphene with paracetamol as analgesics in the accident department. ( Stableforth, PG, 1977)
" Enhanced analgesic and anti-inflammatory activity was observed with S-SMEDD formulations in acetic acid-induced writhings and carrageenan-induced paw edema models, respectively."3.91Mefenamic acid-loaded solid SMEDDS: an innovative aspect for dose reduction and improved pharmacodynamic profile. ( Bedi, N; Kumar, M; Singh, D, 2019)
"The dose-response relation of S-methylisothiourea, rofecoxib, mefenamic acid, and their combination was studied in the late phase of formalin-induced pain in mice over the time spent in licking the hindpaw after formalin injection."3.74The interaction between inhibitors of nitric oxide synthase and cyclooxygenase in formalin-induced pain in mice: an isobolographic study. ( Bhat, AS; Krishna, V; Kumar, D; Prakash, VR; Tandan, SK, 2008)
"A comparison was made between the relative effects of aspirin, mefenamic acid, dihydrocodeine , dextropropoxyphene and paracetamol on visceral pain (chemically-inducing writhing), respiratory rate and prostaglandin (PG) biosynthesis (cyclo-oxygenase activity)."3.67Comparison of the relative effects of aspirin, mefenamic acid, dihydrocodeine, dextropropoxyphene and paracetamol on visceral pain, respiratory rate and prostaglandin biosynthesis. ( Gonzalez, JP; Pugh, J; Sewell, RD, 1984)
"Non-oliguric renal failure developed in six elderly women who had been prescribed 1--2 g of mefenamic acid daily for 2--6 weeks for the relief of musculoskeletal pain."3.66Mefenamic acid nephropathy. ( Dlugolecka, M; Ford, MJ; Prescott, LF; Robertson, CE; Van Someren, V, 1980)
"A double-blind three-way crossover design in the treatment of dysmenorrhea comparing a propionic acid derivative (ibuprofen) and a fenamate (mefenamic acid) with a placebo showed that both ibuprofen and mefenamic acid are generally superior to placebo."3.66A double-blind comparison of a propionic acid derivative (ibuprofen) and a fenamate (mefenamic acid) in the treatment of dysmenorrhea. ( Roy, S, 1983)
" At a dosage of 100mg/kg mouse, the triterpene mixture exhibited 51% analgesic activity but only showed 20% anti-inflammatory activity."1.32Evaluation of the bioactivity of triterpene mixture isolated from Carmona retusa (Vahl.) Masam leaves. ( Canlas, AP; Faustino, KM; Plana, KG; Villaseñor, IM, 2004)

Research

Studies (50)

TimeframeStudies, this research(%)All Research%
pre-199033 (66.00)18.7374
1990's3 (6.00)18.2507
2000's4 (8.00)29.6817
2010's10 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Vivier, D1
Bennis, K1
Lesage, F1
Ducki, S1
Brignardello-Petersen, R1
Kumar, M1
Singh, D1
Bedi, N1
Cimolai, N1
Shirvani, MA1
Motahari-Tabari, N1
Alipour, A1
Gharib, M1
Samani, LN1
Panah, ZE1
Naseri, M1
Bahrani, N1
Kiani, K1
Elzaki, WM1
Abubakr, NH1
Ziada, HM1
Ibrahim, YE1
Cooper, SA1
Desjardins, PJ1
Moradi, A1
Navidpour, L1
Amini, M1
Sadeghian, H1
Shadnia, H1
Firouzi, O1
Miri, R1
Ebrahimi, SE1
Abdollahi, M1
Zahmatkesh, MH1
Shafiee, A1
Jareethum, R1
Suksompong, S1
Petyim, S1
Prechapanich, J1
Laokirkkiat, P1
Choavaratana, R1
Villaseñor, IM2
Angelada, J1
Canlas, AP2
Echegoyen, D1
WINDER, CV1
WAX, J1
SCOTTI, L1
SCHERRER, RA1
JONES, EM1
SHORT, FW1
CASS, LJ1
FREDERIK, WS1
WILLIAMS, MW1
WILLIAMS, CS1
KARTCHNER, MJ1
WINTER, CA1
FLATAKER, L1
Faustino, KM1
Plana, KG1
Buppasiri, P1
Tangmanowutikul, S1
Yoosuk, W1
Bhat, AS1
Tandan, SK1
Kumar, D1
Krishna, V1
Prakash, VR1
Robertson, CE1
Ford, MJ1
Van Someren, V1
Dlugolecka, M1
Prescott, LF1
Amadio, P1
Van Pelt, WL1
Sewell, RD1
Gonzalez, JP1
Pugh, J1
Roy, S1
Barrington, R1
Sleet, RA1
Khan, MA1
Delgado, J1
Simonin, G1
Servier, C1
García, R1
Yoma, J1
Adachi, K1
Nagele, F1
Lockwood, G1
Magos, AL1
Lee, P2
Anderson, JA2
Miller, J2
Webb, J2
Buchanan, WW2
Yanaura, S1
Yamatake, Y1
Misawa, H1
Stableforth, PG1
Parkhouse, J1
DeLeo, JA1
Colburn, RW1
Coombs, DW1
Ellis, MA1
Haig, G1
Hébert, JG1
Le Morvan, P1
Bourgouin, J1
Waltman, R1
Tricomi, V1
Castelli, G1
Collier, HO1
James, GW1
Schneider, C1
Buchmann, E1
Ferris, JE1
Pigott, PV1
Marazzi-Uberti, E1
Lumachi, B1
Gaetani, M1
Coppi, G1
Bianchi, C1
Roszkowski, AP1
Rooks, WH1
Tomolonis, AJ1
Miller, LM1
Steinhäuser, E1
Hirose, K1
Jyoyama, H1
Coltorti, M1
Di Simone, A1
Sugano, T1
Fujimori, I1
Hackl, J1
Kater, RM1

Clinical Trials (6)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Efficacy of Pain Control Following Root Canal Treatment Using Paracetamol Alone and in Combination With Three Different Non-Steroidal Anti-Inflammatory Analgesics[NCT02417337]Phase 2170 participants (Actual)Interventional2012-08-31Completed
Effect of Preoperative, Single-dose Diclofenac Potassium on Postoperative Endodontic Pain in Patients With Symptomatic Irreversible Pulpitis: A Double Blind Randomized Controlled Trial[NCT03341260]Phase 2/Phase 370 participants (Actual)Interventional2016-12-31Completed
Analgesic Efficacy of Preoperative Oral Administration of Dexketoprofen Trometamol in Third Molar Surgery, Compared to Postoperative Administration[NCT02380001]Phase 460 participants (Actual)Interventional2015-01-31Completed
A Full-Factorial, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group, Single-Dose Efficacy and Safety Study of an Acetaminophen/Naproxen Sodium Fixed Combination, Acetaminophen, and Naproxen Sodium in Postoperative Dental Pain[NCT05761574]Phase 3440 participants (Anticipated)Interventional2023-05-22Recruiting
The Effect of Premedication Hyoscine-N-butylbromide Before Hysterosalpingography for Diagnosis of Proximal Tubal Obstruction in Infertile Women : A Randomized Double-Blind Controlled Trial[NCT02618785]146 participants (Actual)Interventional2016-06-30Completed
Efficacy for Acute Pain Alleviation of 50 mg Diclofenac 1 Hour Prior to Endometrial Sampling in Cases of Abnormal Uterine Bleeding[NCT01762306]90 participants (Anticipated)Interventional2012-11-30Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

3 reviews available for mefenamic acid and Ache

ArticleYear
Perspectives on the Two-Pore Domain Potassium Channel TREK-1 (TWIK-Related K(+) Channel 1). A Novel Therapeutic Target?
    Journal of medicinal chemistry, 2016, 06-09, Volume: 59, Issue:11

    Topics: Arrhythmias, Cardiac; Depression; Epilepsy; Humans; Inflammation; Models, Molecular; Molecular Struc

2016
The potential and promise of mefenamic acid.
    Expert review of clinical pharmacology, 2013, Volume: 6, Issue:3

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Female; Fenamates; Humans; Mefenamic Acid; Pain

2013
Simple analgesics.
    Drugs, 1975, Volume: 10, Issue:5-6

    Topics: Acetaminophen; Analgesics; Aspirin; Azepines; Carbamazepine; Codeine; Dextropropoxyphene; Drug Combi

1975

Trials

24 trials available for mefenamic acid and Ache

ArticleYear
The effect of mefenamic acid and ginger on pain relief in primary dysmenorrhea: a randomized clinical trial.
    Archives of gynecology and obstetrics, 2015, Volume: 291, Issue:6

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Dose-Response Relationship, Drug; Dysmenorrhea; Female; Hum

2015
The effect of valeric on anxiety severity in women undergoing hysterosalpingography.
    Global journal of health science, 2015, Apr-02, Volume: 7, Issue:3

    Topics: Adult; Analgesics; Anxiety; Double-Blind Method; Female; Humans; Hysterosalpingography; Infertility,

2015
Double-blind Randomized Placebo-controlled Clinical Trial of Efficiency of Nonsteroidal Anti-inflammatory Drugs in the Control of Post-endodontic Pain.
    Journal of endodontics, 2016, Volume: 42, Issue:6

    Topics: Acetaminophen; Adult; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Dose-

2016
Double-blind Randomized Placebo-controlled Clinical Trial of Efficiency of Nonsteroidal Anti-inflammatory Drugs in the Control of Post-endodontic Pain.
    Journal of endodontics, 2016, Volume: 42, Issue:6

    Topics: Acetaminophen; Adult; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Dose-

2016
Double-blind Randomized Placebo-controlled Clinical Trial of Efficiency of Nonsteroidal Anti-inflammatory Drugs in the Control of Post-endodontic Pain.
    Journal of endodontics, 2016, Volume: 42, Issue:6

    Topics: Acetaminophen; Adult; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Dose-

2016
Double-blind Randomized Placebo-controlled Clinical Trial of Efficiency of Nonsteroidal Anti-inflammatory Drugs in the Control of Post-endodontic Pain.
    Journal of endodontics, 2016, Volume: 42, Issue:6

    Topics: Acetaminophen; Adult; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Dose-

2016
Efficacy of mefenamic acid and hyoscine for pain relief during saline infusion sonohysterography in infertile women: a double blind randomized controlled trial.
    European journal of obstetrics, gynecology, and reproductive biology, 2011, Volume: 155, Issue:2

    Topics: Adult; Double-Blind Method; Endometrium; Female; Humans; Hysteroscopy; Infertility, Female; Mefenami

2011
Randomized controlled trial of mefenamic acid vs paracervical block for relief of pain for outpatient uterine curettage.
    Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 2005, Volume: 88, Issue:7

    Topics: Anesthesia, Obstetrical; Anti-Inflammatory Agents, Non-Steroidal; Dilatation and Curettage; Female;

2005
Single-blind study of diflunisal versus mefenamic acid in the treatment of pain after Colles' fracture.
    Current medical research and opinion, 1980, Volume: 6, Issue:9

    Topics: Adult; Aged; Colles' Fracture; Diflunisal; Female; Humans; Male; Mefenamic Acid; Middle Aged; Pain;

1980
Comparative study of mefenamic acid and dextropropoxyphene plus paracetamol in an accident and emergency department.
    Current medical research and opinion, 1980, Volume: 7, Issue:2

    Topics: Accidents; Acetaminophen; Adolescent; Adult; Aged; Dextropropoxyphene; Double-Blind Method; Drug The

1980
Tolfenamic acid and mefenamic acid in the treatment of primary dysmenorrhoea.
    Pharmacology & toxicology, 1994, Volume: 75 Suppl 2

    Topics: Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Cross-Over Studies; Double-Blind Method;

1994
Randomised placebo controlled trial of mefenamic acid for premedication at outpatient hysteroscopy: a pilot study.
    British journal of obstetrics and gynaecology, 1997, Volume: 104, Issue:7

    Topics: Adult; Aged; Ambulatory Care; Anti-Inflammatory Agents, Non-Steroidal; Female; Humans; Hysteroscopy;

1997
Evaluation of analgesic action and efficacy of antirheumatic drugs. Study of 10 drugs in 684 patients with rheumatoid arthritis.
    The Journal of rheumatology, 1976, Volume: 3, Issue:3

    Topics: Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Aspirin; Clinical Tri

1976
Clinical assessment of analgesics using ultrasonic stimulation. A new method.
    Japanese journal of pharmacology, 1977, Volume: 27, Issue:4

    Topics: Adolescent; Adult; Aminopyrine; Analgesics; Animals; Aspirin; Bromelains; Clinical Trials as Topic;

1977
Mefenamic acid and dextropropoxyphene with paracetamol as analgesics in the accident department.
    Current medical research and opinion, 1977, Volume: 5, Issue:2

    Topics: Acetaminophen; Adult; Aged; Clinical Trials as Topic; Dextropropoxyphene; Double-Blind Method; Drug

1977
[Comparative evaluation of the therapeutic efficiency of flurbiprofene in rheumatoid polyarthritis].
    Revue du rhumatisme et des maladies osteo-articulaires, 1975, Volume: 42, Issue:6

    Topics: Acetaminophen; Arthritis, Rheumatoid; Aspirin; Biphenyl Compounds; Chemical Phenomena; Chemistry; Cl

1975
A double-blind comparison of mefenamic acid and piroxicam in acute soft tissue injuries.
    Current medical research and opinion, 1988, Volume: 10, Issue:10

    Topics: Acute Disease; Adolescent; Adult; Double-Blind Method; Female; Humans; Male; Mefenamic Acid; Middle

1988
Double-blind comparison of ketoprofen and mefenamic acid in the treatment of primary dysmenorrhea.
    Clinical therapeutics, 1986, Volume: 8, Issue:3

    Topics: Adolescent; Adult; Clinical Trials as Topic; Double-Blind Method; Dysmenorrhea; Female; Humans; Keto

1986
Letter: Pentazocine, mefenamic acid and hypertonic-saline abortion.
    Lancet (London, England), 1974, Aug-24, Volume: 2, Issue:7878

    Topics: Abortion, Induced; Female; Humans; Hypertonic Solutions; Mefenamic Acid; Pain; Pentazocine; Pregnanc

1974
[Use of Ponstan in otorhinolaryngologic diseases].
    Schweizerische Rundschau fur Medizin Praxis = Revue suisse de medecine Praxis, 1973, Volume: 62, Issue:30

    Topics: Adult; Child; Clinical Trials as Topic; Evaluation Studies as Topic; Humans; Mefenamic Acid; ortho-A

1973
Mefenamic acid compared with indomethacin and placebo in osteoarthritis.
    Annals of physical medicine, 1966, Volume: Suppl

    Topics: Anti-Inflammatory Agents; Clinical Trials as Topic; Diarrhea; Digestion; Duodenal Ulcer; Female; Fol

1966
Evaluation of mefenamic acid and flufenamic acid in clinical pain.
    Annals of physical medicine, 1966, Volume: Suppl

    Topics: Acetaminophen; Anti-Inflammatory Agents; Clinical Trials as Topic; Flufenamic Acid; Fluorine; Humans

1966
Mefenamic acid as an analgesic.
    The Practitioner, 1970, Volume: 204, Issue:224

    Topics: Acetaminophen; Adolescent; Adult; Aged; Anti-Inflammatory Agents; Clinical Trials as Topic; Drug Syn

1970
[The use of Ponstan in pain and inflammatory conditions following dental surgery].
    Schweizerische Monatsschrift fur Zahnheilkunde = Revue mensuelle suisse d'odonto-stomatologie, 1970, Volume: 80, Issue:4

    Topics: Aminopyrine; Anti-Inflammatory Agents; Edema; Humans; Mefenamic Acid; ortho-Aminobenzoates; Pain; Su

1970
[Double-blind clinical studies of the analgesic activity of mefenamic acid].
    Minerva medica, 1970, Apr-04, Volume: 61, Issue:27

    Topics: Anti-Inflammatory Agents; Aspirin; Humans; Mefenamic Acid; ortho-Aminobenzoates; Pain; Placebos

1970
[Treatment of postoperative pain with mefenamic acid].
    Die Medizinische Welt, 1967, Nov-18, Volume: 46

    Topics: Adolescent; Adult; Aged; Analgesics; Anti-Inflammatory Agents; Female; Humans; Male; Mefenamic Acid;

1967
Double-blind evaluation of the analgesic and toxic effects of flufenamic acid and mefenamic acid in patients with chronic pain.
    The Medical journal of Australia, 1968, May-18, Volume: 1, Issue:20

    Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Flufenamic Acid; Fluorine; Humans; Mefenamic Acid;

1968

Other Studies

23 other studies available for mefenamic acid and Ache

ArticleYear
Curcumin probably does not reduce pain importantly after impacted mandibular third-molar surgery compared with mefenamic acid.
    Journal of the American Dental Association (1939), 2019, Volume: 150, Issue:1

    Topics: Curcumin; Humans; Inflammation; Mefenamic Acid; Molar; Molar, Third; Pain; Tooth Extraction; Tooth,

2019
Mefenamic acid-loaded solid SMEDDS: an innovative aspect for dose reduction and improved pharmacodynamic profile.
    Therapeutic delivery, 2019, Volume: 10, Issue:1

    Topics: Acetic Acid; Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Biological Avai

2019
The value of the dental impaction pain model in drug development.
    Methods in molecular biology (Clifton, N.J.), 2010, Volume: 617

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Drug Design; Human

2010
The value of the dental impaction pain model in drug development.
    Methods in molecular biology (Clifton, N.J.), 2010, Volume: 617

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Drug Design; Human

2010
The value of the dental impaction pain model in drug development.
    Methods in molecular biology (Clifton, N.J.), 2010, Volume: 617

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Drug Design; Human

2010
The value of the dental impaction pain model in drug development.
    Methods in molecular biology (Clifton, N.J.), 2010, Volume: 617

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Drug Design; Human

2010
Design and synthesis of 2-phenoxynicotinic acid hydrazides as anti-inflammatory and analgesic agents.
    Archiv der Pharmazie, 2010, Volume: 343, Issue:9

    Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase 1; Cyclooxygenase 2; Cy

2010
Bioactivity studies on beta-sitosterol and its glucoside.
    Phytotherapy research : PTR, 2002, Volume: 16, Issue:5

    Topics: Acetic Acid; Analgesics; Animals; Anthelmintics; Anti-Inflammatory Agents; Ascaris suum; Drug Evalua

2002
Anti-inflammatory, antipyretic and antinociceptive properties of N-(2,3-xylyl)anthranilic acid (mefenamic acid).
    The Journal of pharmacology and experimental therapeutics, 1962, Volume: 138

    Topics: Analgesics; Anaphylaxis; Anti-Inflammatory Agents; Antipyretics; Humans; Inflammation; Mefenamic Aci

1962
Experiments in relief of clinical pain with N-(2,3-xylyl)-anthranilic acid (CI-473; mefenamic acid).
    The Journal of pharmacology and experimental therapeutics, 1963, Volume: 139

    Topics: Analgesics; Analgesics, Non-Narcotic; Antipyretics; Humans; Mefenamic Acid; ortho-Aminobenzoates; Pa

1963
ISCHEMIC ARM PAIN AND THE NONNARCOTIC ANALGESIC MEFENAMIC ACID, N-(2,3-XYLYL)ANTHRANILIC ACID.
    Toxicology and applied pharmacology, 1965, Volume: 7

    Topics: Analgesics; Analgesics, Non-Narcotic; Antipyretics; Arm; Aspirin; Biomedical Research; Ischemia; Mef

1965
NOCICEPTIVE THRESHOLDS AS AFFECTED BY PARENTERAL ADMINISTRATION OF IRRITANTS AND OF VARIOUS ANTINOCICEPTIVE DRUGS.
    The Journal of pharmacology and experimental therapeutics, 1965, Volume: 148

    Topics: Aminopyrine; Analgesics; Analgesics, Non-Narcotic; Antipyretics; Aspirin; Flufenamic Acid; Indoles;

1965
Evaluation of the bioactivity of triterpene mixture isolated from Carmona retusa (Vahl.) Masam leaves.
    Journal of ethnopharmacology, 2004, Volume: 92, Issue:1

    Topics: Acetic Acid; Analgesics; Animals; Anti-Infective Agents; Anti-Inflammatory Agents, Non-Steroidal; An

2004
The interaction between inhibitors of nitric oxide synthase and cyclooxygenase in formalin-induced pain in mice: an isobolographic study.
    Anesthesia and analgesia, 2008, Volume: 106, Issue:3

    Topics: Animals; Behavior, Animal; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxy

2008
Mefenamic acid nephropathy.
    Lancet (London, England), 1980, Aug-02, Volume: 2, Issue:8188

    Topics: Aged; Creatinine; Female; Humans; Kidney Concentrating Ability; Kidney Failure, Chronic; Mefenamic A

1980
Peripherally acting analgesics.
    The American journal of medicine, 1984, Sep-10, Volume: 77, Issue:3A

    Topics: Acetaminophen; Analgesics; Anti-Inflammatory Agents; Aspirin; Diflunisal; Fenoprofen; Humans; Ibupro

1984
Postoperative management of pain by the use of ponstel (mefenamic acid), a nonsteroidal anti-inflammatory agent.
    The Journal of foot surgery, 1983,Spring, Volume: 22, Issue:1

    Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Female; Foot; Foot Diseases; Humans; Male; Mefenam

1983
Comparison of the relative effects of aspirin, mefenamic acid, dihydrocodeine, dextropropoxyphene and paracetamol on visceral pain, respiratory rate and prostaglandin biosynthesis.
    Archives internationales de pharmacodynamie et de therapie, 1984, Volume: 268, Issue:2

    Topics: Acetaminophen; Analgesics; Animals; Aspirin; Codeine; Dextropropoxyphene; Male; Mefenamic Acid; Mice

1984
A double-blind comparison of a propionic acid derivative (ibuprofen) and a fenamate (mefenamic acid) in the treatment of dysmenorrhea.
    Obstetrics and gynecology, 1983, Volume: 61, Issue:5

    Topics: Adult; Double-Blind Method; Dysmenorrhea; Female; Humans; Ibuprofen; Mefenamic Acid; Pain

1983
A device for automatic measurement of writhing and its application to the assessment of analgesic agents.
    Journal of pharmacological and toxicological methods, 1994, Volume: 32, Issue:2

    Topics: Acetates; Acetic Acid; Aminopyrine; Analgesics; Animals; Behavior, Animal; Caffeine; Disease Models,

1994
The differentiation of NSAIDs and prostaglandin action using a mechanical visceral pain model in the rat.
    Pharmacology, biochemistry, and behavior, 1989, Volume: 33, Issue:1

    Topics: Acetates; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Disease Models, Animal; Dose-Re

1989
Antagonism by aspirin and fenamates of bronchoconstriction and nociception induced by adenosine-5'-triphosphate.
    Nature, 1966, Oct-22, Volume: 212, Issue:5060

    Topics: Acetylcholine; Adenine Nucleotides; Adenosine Triphosphate; Anaphylaxis; Animals; Anti-Inflammatory

1966
Pharmacological investigations of 4-prenyl-1,2-diphenyl-3,5-pyrazolidinedione (DA 2370). 7. Pharmacological comparison with standard anti-inflammatory drugs.
    Arzneimittel-Forschung, 1972, Volume: 22, Issue:1

    Topics: Animals; Anti-Inflammatory Agents; Benzyl Compounds; Edema; Female; Fever; Flufenamic Acid; Indometh

1972
Anti-inflammatory and analgetic properties of d-2-(6'-methoxy-2'-naphthyl)-propionic acid (naproxen).
    The Journal of pharmacology and experimental therapeutics, 1971, Volume: 179, Issue:1

    Topics: Analgesics; Analysis of Variance; Animals; Anti-Inflammatory Agents; Aspirin; Carrageenan; Edema; Fe

1971
Measurement of arthritic pain and effects of analgesics in the adjuvant-treated rat.
    Japanese journal of pharmacology, 1971, Volume: 21, Issue:6

    Topics: Adjuvants, Immunologic; Aminopyrine; Analgesics; Animals; Arthritis; Aspirin; Female; Hydrocortisone

1971
[Clinical aspecs of the anti-inflammatory drugs in the surgical and orthopedic fields].
    Horumon to rinsho. Clinical endocrinology, 1970, Volume: 18, Issue:3

    Topics: Analgesics; Anti-Inflammatory Agents; Arthritis; Gout; Humans; Indomethacin; Joint Diseases; Mefenam

1970