medroxyprogesterone acetate has been researched along with Disease Models, Animal in 63 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (6.35) | 18.7374 |
| 1990's | 7 (11.11) | 18.2507 |
| 2000's | 21 (33.33) | 29.6817 |
| 2010's | 28 (44.44) | 24.3611 |
| 2020's | 3 (4.76) | 2.80 |
| Authors | Studies |
|---|---|
| Abrams, RPM; Bachani, M; Balasubramanian, A; Brimacombe, K; Dorjsuren, D; Eastman, RT; Hall, MD; Jadhav, A; Lee, MH; Li, W; Malik, N; Nath, A; Padmanabhan, R; Simeonov, A; Steiner, JP; Teramoto, T; Yasgar, A; Zakharov, AV | 1 |
| Balogh, KK; Brendle, SA; Christensen, ND; Cladel, NM; Cooper, T; Hu, J; Li, JJ; Shearer, DA; Walter, V | 1 |
| Agnes, JP; Báfica, A; Bishop, AJR; Bruxel, MA; Casagrande, T; Cassali, GD; das Neves, RN; Delgobo, M; Falchetti, M; Garcia, APV; Gelain, DP; Gonçalves, RM; Mendes, DAGB; Moreira, JCF; Rafacho, A; Somensi, N; Vieira, TC; Zanotto-Filho, A | 1 |
| Chai, W; Chen, Q; Fan, Y; Fu, Y; Guo, H; Kuang, Y; Lyu, Q; Wen, X; Xie, J; Yan, Z; Yu, B; Zhou, L | 1 |
| Medeiros, FDC; Pereira, FEXG; Rocha, HAL; Silva, KSD | 1 |
| Aslan, E; Ciftci, S; Dogruer, G; Dolapcioglu, K; Ergun, Y; Ozsoy, S; Soylu Karapinar, O | 1 |
| Besch-Williford, CL; Cook, M; Hyder, SM; Mafuvadze, B; Xu, Z | 1 |
| Deyounks, F; Ellis, S; García-Lerma, JG; Hanley, K; Heneine, W; Jenkins, L; Mitchell, J; Radzio, J | 1 |
| Aravantinou, M; Blanchard, J; Derby, N; Frank, I; Gettie, A; Grasperge, B; Kenney, J; Kleinbeck, K; Lifson, JD; Piatak, M; Robbiani, M; Zydowsky, TM | 1 |
| Amos-Landgraf, JM; Clipson, L; Dove, WF; Dunkin, E; Ederveen, AG; Groothuis, PG; Heijmans, J; Hommes, DW; Krentz, KJ; Mosselman, S; Muncan, V; Shedlovsky, A; van den Brink, GR; Wielenga, MC | 1 |
| Chen, C; Ge, GZ; He, BL; Jiao, JL; Lv, LB; Wang, CY; Xia, HJ; Zhang, HL; Zhang, YX | 1 |
| Almeida, PR; Dias, BH; Guimarães, SB; Medeiros, Fd; Pereira, FE; Vasconcelos, PR | 1 |
| Butler, K; Ellis, S; Garber, D; Henning, TR; Kersh, EN; McNicholl, JM; Montague, J; Ritter, J; Zaki, S | 1 |
| Jin, GL; Li, SP; Liu, M; Qiu, HQ; Xu, Y; Yang, J; Yu, CX | 1 |
| Altan, M; Bruner-Tran, KL; Denis, D; Gotteland, JP; Nataraja, SG; Osteen, KG; Palmer, SS; Tos, EG | 1 |
| Chai, DC; D'Hooghe, TM; Gotteland, JP; Hussein, M; Kyama, CM; Mwenda, JM; Palmer, SS | 1 |
| Honda, R; Katabuchi, H; Ohba, T; Saito, F; Suzuki, A; Tashiro, H; Yamaguchi, M | 1 |
| Boyaka, PN; Cherpes, TL; Hall-Stoodley, L; Kaur, B; Pavelko, SD; Quispe Calla, NE; Trout, W; Vicetti Miguel, RD | 1 |
| Butler, K; Ellis, S; Hanson, DL; Kersh, EN; McNicholl, JM; Morris, MR; Ritter, JM | 1 |
| Baik, S; Chung, SH; Mehta, FF | 1 |
| Ebner, CA; Elovitz, MA; Yellon, SM | 1 |
| Alpers, CE; Clark, EA; Elkon, KB; Hudkins, KL; Hughes, GC; Martin, D; Zhang, K | 1 |
| Aouad, M; Charlet, A; Poisbeau, P; Rodeau, JL | 1 |
| Fischer, JW; Freudenberger, T; Heim, HK; Kojda, G; Marzoll, A; Mayer, P; Oppermann, M; Schrör, K; Weber, AA | 1 |
| Celik, HH; Erbas, D; Kilic, S; Kormaz, A; Lortlar, N; Omeroglu, S; Peker, T; Tatar, I; Zulfikaroglu, E | 1 |
| Frye, CA; Paris, JJ; Walf, AA | 1 |
| Branstetter, D; Dougall, WC; Erwert, R; Gonzalez-Suarez, E; Jacob, AP; Jones, J; Miller, R; Pinkas, J; Roudier-Meyer, MP | 1 |
| Baldi, A; Cerliani, JP; Giulianelli, S; Gongora, A; Lamb, CE; Lanari, C; Molinolo, A; Sahores, A; Wargon, V | 1 |
| Albayrak, BS; Gorgulu, A; Ismailoglu, O; Sahin, B | 1 |
| Chen, SZ; Zhang, YL | 1 |
| Kimura, K; Nishida, T; Orita, T; Sonoda, KH; Zhou, H | 1 |
| Ai, Z; Teng, Y; Tong, J; Wang, J; Xu, Y | 1 |
| Carmichael, JR; de la Maza, LM; Pal, S; Tifrea, D | 1 |
| Singh, M; Su, C | 1 |
| Allie, N; Du Plessis, N; Jacobs, M; Kidd, M; Kleynhans, L; Ronacher, K; van Helden, PD; Walzl, G | 1 |
| Adakan, S; Karadadas, N; Ozsener, S; Oztekin, K; Sagol, S; Yoldemir, T | 1 |
| Anthony, MS; Clarkson, TB; Mikkola, TS; St Clair, RW | 1 |
| Barnes, MN; Berry, WD; Grizzle, WE; Huh, WK; Kirby, TO; Leath, CA; Partridge, EE; Straughn, JM | 1 |
| Chiba, K; Hosokawa, M; Kobayashi, K; Mimura, N; Nakamura, Y; Shimada, N | 1 |
| Abel, K; Bost, K; Lu, D; McChesney, MB; Miller, CJ; Rourke, T | 1 |
| Dalsgaard, T; Lund, CO; Nilas, L; Ottesen, B; Pedersen, NG; Pedersen, SH | 1 |
| Jordan, VC | 1 |
| Fox, JL; Koudy Williams, J; Suparto, IH; Vinten-Johansen, J | 1 |
| Benakanakere, I; Besch-Williford, C; Brandt, S; Ellersieck, MR; Hyder, SM; Molinolo, A; Schnell, J | 1 |
| Kaya, U; Kuscu, E; Oktem, M; Ozen, O; Zeyneloglu, HB | 1 |
| Booth, EA; Lucchesi, BR | 1 |
| Cetinkaya, MB; Kandemir, B; Kefeli, M; Kokcu, A; Ocal, G; Tosun, M | 1 |
| Chapman, W; Fyles, A; Gowing, K; Khokha, R; Li, M; Manoukian, AS; Tsao, MS; Wood, G | 1 |
| Elovitz, MA; Gonzalez, J | 1 |
| Murphy, GP | 1 |
| Kärki, NT; Saarni, HU; Sotaniemi, EA; Stengård, J | 1 |
| Itoh, N; Mori, H; Morishita, S; Murase, T; Niwa, K; Tamaya, T; Tanaka, T | 1 |
| Bozzola, JJ; Drew, MD; Kepple, L; McDermott, MR; Parr, EL; Parr, MB | 1 |
| Deerberg, F; Horn, DW; Schneider, MR; Vollmer, G | 1 |
| Cohen, J | 1 |
| Carlson, CS; Jayo, MJ; Register, TC | 1 |
| Acs, N; Miklós, Z; Monos, E; Nádasy, GL; Székács, B; Szentiványi, M; Várbíró, S | 1 |
| Andrade, PM; Baracat, EC; Rodrigues de Lima, G; Simões, MJ | 1 |
| Fabris, V; Helguero, LA; Lamb, CA; Lanari, C; Lüthy, I; Merani, S; Molinolo, AA; Pagano, E; Sanjuan, N | 1 |
| Keisler, LW; Kier, AB; Walker, SE | 1 |
| Coe, JE; Ross, MJ | 1 |
| Banna, NE; el Habashy, MA; Nayel, SA; Sehrawy, SA | 1 |
1 review(s) available for medroxyprogesterone acetate and Disease Models, Animal
| Article | Year |
|---|---|
Progesterone-induced neuroprotection: factors that may predict therapeutic efficacy.
Topics: Animals; Disease Models, Animal; Humans; Medroxyprogesterone Acetate; Nervous System Diseases; Neurons; Neuroprotective Agents; Predictive Value of Tests; Progesterone | 2013 |
62 other study(ies) available for medroxyprogesterone acetate and Disease Models, Animal
| Article | Year |
|---|---|
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Drug Evaluation, Preclinical; High-Throughput Screening Assays; Immunocompetence; Inhibitory Concentration 50; Methacycline; Mice, Inbred C57BL; Protease Inhibitors; Quantitative Structure-Activity Relationship; Small Molecule Libraries; Vero Cells; Zika Virus; Zika Virus Infection | 2020 |
Depo Medroxyprogesterone (DMPA) Promotes Papillomavirus Infections but Does Not Accelerate Disease Progression in the Anogenital Tract of a Mouse Model.
Topics: Animals; Contraceptive Agents; Disease Models, Animal; Disease Progression; Estradiol; Female; Humans; Medroxyprogesterone; Medroxyprogesterone Acetate; Mice; Mice, Nude; Papillomavirus Infections | 2022 |
COX-2 promotes mammary adipose tissue inflammation, local estrogen biosynthesis, and carcinogenesis in high-sugar/fat diet treated mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Aromatase; Breast Neoplasms; Cell Line, Tumor; Chemokine CCL2; Cyclooxygenase 2; Diet, High-Fat; Dinoprostone; Disease Models, Animal; Etoricoxib; Female; Gene Expression Regulation, Neoplastic; Humans; Interleukin-6; MCF-7 Cells; Medroxyprogesterone Acetate; Mice; Sugars; Up-Regulation | 2021 |
The role of combining medroxyprogesterone 17-acetate with human menopausal gonadotropin in mouse ovarian follicular development.
Topics: Animals; Disease Models, Animal; Female; Hormones; Humans; Medroxyprogesterone Acetate; Menopause; Menotropins; Mice; Mice, Inbred BALB C; Ovarian Follicle; Ovulation Induction; Random Allocation; Signal Transduction; Treatment Outcome | 2018 |
Effects of omega-6/3 and omega-9/6 nutraceuticals on pain and fertility in peritoneal endometriosis in rats.
Topics: Animals; Disease Models, Animal; Endometriosis; Fatty Acids, Omega-3; Female; Fertility; Medroxyprogesterone Acetate; Meloxicam; Pain; Peritoneum; Rats | 2019 |
Theranekron for treatment of endometriosis in a rat model compared with medroxyprogesterone acetate and leuprolide acetate.
Topics: Animals; Antineoplastic Agents, Hormonal; Disease Models, Animal; Endometriosis; Endometrium; Female; Leuprolide; Medroxyprogesterone Acetate; Random Allocation; Rats; Secondary Prevention; Spider Venoms | 2013 |
Effects of dietary apigenin on tumor latency, incidence and multiplicity in a medroxyprogesterone acetate-accelerated 7,12-dimethylbenz(a)anthracene-induced breast cancer model.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Apigenin; Breast Neoplasms; Dietary Supplements; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Hormone Replacement Therapy; Mammary Neoplasms, Experimental; Medroxyprogesterone Acetate; Postmenopause; Rats; Rats, Sprague-Dawley | 2013 |
Depot-medroxyprogesterone acetate does not reduce the prophylactic efficacy of emtricitabine and tenofovir disoproxil fumarate in macaques.
Topics: Adenine; Animals; Anti-HIV Agents; Contraceptive Agents, Female; Delayed-Action Preparations; Deoxycytidine; Disease Models, Animal; Drug Interactions; Drug Therapy, Combination; Emtricitabine; Female; HIV Infections; Macaca nemestrina; Medroxyprogesterone Acetate; Phosphorous Acids; Pre-Exposure Prophylaxis; Treatment Outcome | 2014 |
Short communication: a repeated simian human immunodeficiency virus reverse transcriptase/herpes simplex virus type 2 cochallenge macaque model for the evaluation of microbicides.
Topics: Animals; Anti-Infective Agents; Coinfection; Contraceptive Agents, Female; Disease Models, Animal; Female; Herpes Genitalis; Herpesvirus 2, Human; HIV Reverse Transcriptase; Macaca mulatta; Medroxyprogesterone Acetate; Simian Acquired Immunodeficiency Syndrome; Simian Immunodeficiency Virus; Treatment Outcome; Vagina; Vaginal Creams, Foams, and Jellies; Virus Shedding | 2014 |
Sex disparity in colonic adenomagenesis involves promotion by male hormones, not protection by female hormones.
Topics: Adenoma; Adenomatous Polyposis Coli; Animals; Animals, Congenic; Azoxymethane; Carcinogens; Colonic Neoplasms; Dihydrotestosterone; Disease Models, Animal; Estradiol; Female; Genes, APC; Gonadal Steroid Hormones; Hormone Replacement Therapy; Humans; Male; Medroxyprogesterone Acetate; Mice; Mice, Inbred C57BL; Mutation; Neoplasms, Hormone-Dependent; Orchiectomy; Organ Specificity; Ovariectomy; Postmenopause; Random Allocation; Rats; Rats, Inbred F344; Rats, Mutant Strains; Receptors, Androgen; RNA, Messenger; Sex Distribution; Species Specificity | 2014 |
PTEN/PIK3CA genes are frequently mutated in spontaneous and medroxyprogesterone acetate-accelerated 7,12-dimethylbenz(a)anthracene-induced mammary tumours of tree shrews.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Carcinoma, Ductal, Breast; Carcinoma, Papillary; Disease Models, Animal; Estrogens; Female; Mammary Glands, Animal; Mammary Neoplasms, Animal; Mammary Neoplasms, Experimental; Medroxyprogesterone Acetate; Mutation; Papilloma, Intraductal; Phosphatidylinositol 3-Kinase; Progesterone; PTEN Phosphohydrolase; Random Allocation; Receptors, Estrogen; Receptors, Progesterone; Tupaiidae | 2014 |
Development of a subcutaneous endometriosis rat model.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents, Hormonal; Aspirin; Connective Tissue Diseases; Disease Models, Animal; Dose-Response Relationship, Drug; Endometriosis; Estradiol; Estrogens; Female; Medroxyprogesterone Acetate; Rats, Wistar; Reproducibility of Results; Subcutaneous Tissue; Time Factors; Triptorelin Pamoate | 2015 |
Analysis of putative mucosal SHIV susceptibility factors during repeated DMPA treatments in pigtail macaques.
Topics: Animals; Contraceptive Agents, Female; Disease Models, Animal; Disease Susceptibility; Dose-Response Relationship, Drug; Female; Humans; Hydrogen-Ion Concentration; Macaca nemestrina; Medroxyprogesterone Acetate; Menstrual Cycle; Mucous Membrane; Progesterone; Simian Acquired Immunodeficiency Syndrome; Simian Immunodeficiency Virus; Vagina | 2015 |
Koumine enhances spinal cord 3α-hydroxysteroid oxidoreductase expression and activity in a rat model of neuropathic pain.
Topics: 3-alpha-Hydroxysteroid Dehydrogenase (B-Specific); Analgesics; Animals; Biocatalysis; Chronic Disease; Constriction; Disease Models, Animal; Gene Expression Regulation, Enzymologic; Hyperalgesia; Immunohistochemistry; Indole Alkaloids; Injections, Subcutaneous; Male; Medroxyprogesterone Acetate; Neuralgia; Rats, Sprague-Dawley; RNA, Messenger; Sciatic Nerve; Spinal Cord; Spinal Cord Dorsal Horn | 2015 |
Bentamapimod (JNK Inhibitor AS602801) Induces Regression of Endometriotic Lesions in Animal Models.
Topics: Adult; Animals; Benzothiazoles; Cytokines; Disease Models, Animal; Endometriosis; Endometrium; Enzyme Inhibitors; Female; Humans; JNK Mitogen-Activated Protein Kinases; Killer Cells, Natural; MAP Kinase Signaling System; Matrix Metalloproteinase 3; Medroxyprogesterone Acetate; Mice; Mice, Nude; Progesterone; Pyrimidines; Rats | 2016 |
c-Jun NH2-terminal kinase inhibitor bentamapimod reduces induced endometriosis in baboons: an assessor-blind placebo-controlled randomized study.
Topics: Animals; Benzothiazoles; Disease Models, Animal; Drug Therapy, Combination; Endometriosis; Endometrium; Female; Gonadotropin-Releasing Hormone; Hormones; JNK Mitogen-Activated Protein Kinases; Laparoscopy; Medroxyprogesterone Acetate; Menstrual Cycle; Papio anubis; Protein Kinase Inhibitors; Pyrimidines; Random Allocation; Signal Transduction; Time Factors | 2016 |
Development of a mouse model for testing therapeutic agents: the anticancer effect of dienogest on endometrial neoplasms.
Topics: Animals; Antineoplastic Agents, Hormonal; Disease Models, Animal; Endometrial Neoplasms; Female; Medroxyprogesterone Acetate; Mice; Nandrolone; Progestins; Treatment Outcome | 2016 |
Medroxyprogesterone acetate and levonorgestrel increase genital mucosal permeability and enhance susceptibility to genital herpes simplex virus type 2 infection.
Topics: Animals; Contraceptive Agents, Female; Disease Models, Animal; Disease Susceptibility; Estrogens; Female; Herpes Genitalis; Herpesvirus 2, Human; Levonorgestrel; Medroxyprogesterone Acetate; Mice; Mucous Membrane; Permeability; Vagina | 2016 |
A Depot Medroxyprogesterone Acetate Dose That Models Human Use and Its Effect on Vaginal SHIV Acquisition Risk.
Topics: Animals; Contraceptive Agents, Female; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Macaca nemestrina; Medroxyprogesterone Acetate; Simian Acquired Immunodeficiency Syndrome; Simian Immunodeficiency Virus; Vagina | 2016 |
Recurrence of cervical cancer and its resistance to progestin therapy in a mouse model.
Topics: Animals; Antineoplastic Agents, Hormonal; Disease Models, Animal; Drug Resistance, Neoplasm; Female; Male; Medroxyprogesterone Acetate; Mice; Mice, Transgenic; Neoplasm Recurrence, Local; Oncogene Proteins, Viral; Papillomavirus E7 Proteins; Repressor Proteins; Treatment Failure; Tumor Burden; Uterine Cervical Neoplasms | 2017 |
Medroxyprogesterone acetate modulates remodeling, immune cell census, and nerve fibers in the cervix of a mouse model for inflammation-induced preterm birth.
Topics: Animals; Cervical Ripening; Cervix Uteri; Collagen; Disease Models, Animal; Female; Gestational Age; Inflammation; Injections, Intramuscular; Lipopolysaccharides; Macrophages; Medroxyprogesterone Acetate; Mice; Nerve Fibers; Neutrophil Infiltration; Pregnancy; Premature Birth; Progestins | 2009 |
Decrease in glomerulonephritis and Th1-associated autoantibody production after progesterone treatment in NZB/NZW mice.
Topics: Animals; Autoantibodies; B7-2 Antigen; Complement C3; Disease Models, Animal; DNA; Dose-Response Relationship, Drug; Female; Glomerulonephritis; Immunoglobulin G; Kidney; Lupus Erythematosus, Systemic; Medroxyprogesterone Acetate; Mice; Mice, Inbred NZB; Progesterone; Proteinuria; Th1 Cells | 2009 |
Reduction and prevention of vincristine-induced neuropathic pain symptoms by the non-benzodiazepine anxiolytic etifoxine are mediated by 3alpha-reduced neurosteroids.
Topics: Analysis of Variance; Animals; Anti-Anxiety Agents; Chi-Square Distribution; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Hyperalgesia; Medroxyprogesterone Acetate; Neurotransmitter Agents; Oxazines; Pain Measurement; Pain Threshold; Physical Stimulation; Rats; Rats, Sprague-Dawley; Reaction Time; Time Factors; Vincristine | 2009 |
Differential effects of medroxyprogesterone acetate on thrombosis and atherosclerosis in mice.
Topics: Animals; Antineoplastic Agents, Hormonal; Apolipoproteins E; Atherosclerosis; Disease Models, Animal; Drug Therapy, Combination; Estradiol; Estrogens; Medroxyprogesterone Acetate; Mice; Mice, Knockout; Myocytes, Smooth Muscle; Ovariectomy; Platelet Activation; Thrombin; Thrombosis | 2009 |
The long-term effects of progesterone-only contraceptives on endometrium and ovary in rats.
Topics: Animals; Contraceptive Agents, Female; Delayed-Action Preparations; Desogestrel; Disease Models, Animal; Endometrium; Female; Medroxyprogesterone Acetate; Ovary; Progesterone; Rats; Rats, Wistar; Time Factors; Uterine Hemorrhage | 2010 |
Conjugated equine estrogen, with medroxyprogesterone acetate, enhances formation of 5alpha-reduced progestogens and reduces anxiety-like behavior of middle-aged rats.
Topics: 20-alpha-Dihydroprogesterone; Animals; Anxiety; Behavior, Animal; Desoxycorticosterone; Disease Models, Animal; Drug Therapy, Combination; Estrogens, Conjugated (USP); Female; Hippocampus; Maze Learning; Medroxyprogesterone Acetate; Progesterone; Rats; Rats, Long-Evans | 2010 |
RANK ligand mediates progestin-induced mammary epithelial proliferation and carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Breast Neoplasms; Cell Proliferation; Cell Transformation, Neoplastic; Disease Models, Animal; Epithelial Cells; Female; Humans; Lung Neoplasms; Mammary Neoplasms, Experimental; Mammary Tumor Virus, Mouse; Medroxyprogesterone Acetate; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neoplasm Invasiveness; Precancerous Conditions; Progesterone; Progestins; RANK Ligand; Receptor Activator of Nuclear Factor-kappa B | 2010 |
Mifepristone inhibits MPA-and FGF2-induced mammary tumor growth but not FGF2-induced mammary hyperplasia.
Topics: Animals; Disease Models, Animal; Female; Fibroblast Growth Factor 2; Hormone Antagonists; Hyperplasia; Mammary Glands, Animal; Mammary Neoplasms, Animal; Medroxyprogesterone Acetate; Mice; Mifepristone | 2010 |
The effects of medroxy progesterone acetate on the pro-inflammatory cytokines, TNF-alpha and IL-1beta in the early phase of the spinal cord injury.
Topics: Animals; Disease Models, Animal; Drug Evaluation, Preclinical; Interleukin-1beta; Male; Medroxyprogesterone Acetate; Rats; Rats, Wistar; Spinal Cord Injuries; Time Factors; Tumor Necrosis Factor-alpha | 2011 |
Treatment of cancer cachexia in mice by combination of dsRNA-dependent protein kinase inhibitor and medroxyprogesterone acetate.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Blood Glucose; Body Weight; Cachexia; Cytokines; Disease Models, Animal; eIF-2 Kinase; Humans; Male; Medroxyprogesterone Acetate; Mice; Mice, Inbred BALB C; Muscle, Skeletal; Neoplasms; Protein Kinase Inhibitors; Tumor Burden | 2012 |
Inhibition by medroxyprogesterone acetate of interleukin-1β-induced collagen degradation by corneal fibroblasts.
Topics: Animals; Cell Proliferation; Cells, Cultured; Collagen; Cornea; Disease Models, Animal; Fibroblasts; Immunoblotting; Interleukin-1beta; Male; Matrix Metalloproteinases; Medroxyprogesterone Acetate; Rabbits; Tissue Inhibitor of Metalloproteinases | 2012 |
Epidermal growth factor receptor signaling pathway involved in progestin-resistance of human endometrial carcinoma: In a mouse model.
Topics: Animals; Antineoplastic Agents, Hormonal; Carcinoma; Cell Line, Tumor; Disease Models, Animal; Drug Resistance, Neoplasm; Drug Therapy, Combination; Endometrial Neoplasms; ErbB Receptors; Female; Gefitinib; Humans; Immunohistochemistry; Medroxyprogesterone Acetate; Mice; Mice, Inbred BALB C; Phosphorylation; Quinazolines; Receptors, Progesterone; Signal Transduction; Xenograft Model Antitumor Assays | 2012 |
Differences in infectivity and induction of infertility: a comparative study of Chlamydia trachomatis strains in the murine model.
Topics: Animals; Chlamydia Infections; Chlamydia trachomatis; Disease Models, Animal; Female; Fertility; Infertility; Male; Medroxyprogesterone Acetate; Mice; Mice, Inbred C3H; Statistics, Nonparametric; Vagina | 2013 |
The contraceptive depot medroxyprogesterone acetate impairs mycobacterial control and inhibits cytokine secretion in mice infected with Mycobacterium tuberculosis.
Topics: Animals; Contraceptive Agents; Cytokines; Disease Models, Animal; Female; Immunologic Factors; Immunosuppression Therapy; Medroxyprogesterone Acetate; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mycobacterium tuberculosis; Tuberculosis | 2013 |
Comparison of the reduction of postoperative adhesions by two barriers, one solution, and two pharmacologic agents in the rat uterine model.
Topics: Animals; Biocompatible Materials; Carboxymethylcellulose Sodium; Cellulose, Oxidized; Disease Models, Animal; Double-Blind Method; Drug Therapy, Combination; Female; Fertility Agents, Female; Hyaluronic Acid; Leuprolide; Medroxyprogesterone Acetate; Membranes, Artificial; Postoperative Complications; Progesterone Congeners; Rats; Rats, Wistar; Tissue Adhesions | 2002 |
Comparison of tibolone and conjugated equine estrogens effects on carotid artery atherosclerosis of postmenopausal monkeys.
Topics: Animals; Carotid Artery Diseases; Carotid Artery, Common; Carotid Artery, Internal; Cholesterol, HDL; Cholesterol, VLDL; Diet, Atherogenic; Disease Models, Animal; Disease Progression; Drug Therapy, Combination; Estrogen Receptor Modulators; Estrogen Replacement Therapy; Estrogens, Conjugated (USP); Female; Lipoproteins, LDL; Macaca fascicularis; Medroxyprogesterone Acetate; Norpregnenes; Postmenopause; Time; Vascular Patency | 2002 |
A pilot study of ovarian cancer chemoprevention using medroxyprogesterone acetate in an avian model of spontaneous ovarian carcinogenesis.
Topics: Adenocarcinoma; Animals; Anticarcinogenic Agents; Chickens; Disease Models, Animal; Female; Medroxyprogesterone Acetate; Ovarian Neoplasms; Ovulation; Pilot Projects | 2002 |
Metabolism of medroxyprogesterone acetate (MPA) via CYP enzymes in vitro and effect of MPA on bleeding time in female rats in dependence on CYP activity in vivo.
Topics: Animals; Bleeding Time; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Disease Models, Animal; Enzyme Induction; Enzyme Inhibitors; Isoenzymes; Male; Medroxyprogesterone Acetate; Microsomes, Liver; Phenobarbital; Proadifen; Rats; Rats, Wistar; Recombinant Proteins; Thrombophilia | 2003 |
Abrogation of attenuated lentivirus-induced protection in rhesus macaques by administration of depo-provera before intravaginal challenge with simian immunodeficiency virus mac239.
Topics: AIDS Vaccines; Animals; Antibodies, Viral; CD4 Lymphocyte Count; Disease Models, Animal; Female; Interferon-gamma; Lymphocyte Activation; Macaca mulatta; Medroxyprogesterone Acetate; RNA, Viral; SAIDS Vaccines; Simian Acquired Immunodeficiency Syndrome; Simian Immunodeficiency Virus; T-Lymphocytes; Vaccines, Attenuated; Viral Load | 2004 |
Progestins used in hormonal replacement therapy display different effects in coronary arteries from New Zealand white rabbits.
Topics: Acetylcholine; Animals; Arteries; Calcium; Coronary Vessels; Disease Models, Animal; Endothelin-1; Estradiol; Estrogen Replacement Therapy; Estrogens, Conjugated (USP); Female; Medroxyprogesterone Acetate; Menopause; NG-Nitroarginine Methyl Ester; Nitroprusside; Norethindrone; Norethindrone Acetate; Ovariectomy; Potassium; Progestins; Rabbits; Vasoconstriction; Vasodilation | 2004 |
Medroxyprogesterone acetate and metastases: of mice and (wo)men.
Topics: Animals; Antineoplastic Agents, Hormonal; Biomarkers, Tumor; Breast Neoplasms; Disease Models, Animal; Female; Genes, Tumor Suppressor; Humans; Medroxyprogesterone Acetate; Mice; NM23 Nucleoside Diphosphate Kinases; Nucleoside-Diphosphate Kinase | 2005 |
A comparison of two progestins on myocardial ischemia-reperfusion injury in ovariectomized monkeys receiving estrogen therapy.
Topics: Animals; Biomarkers; Blood Flow Velocity; Blood Pressure; Body Weight; Contraceptive Agents, Female; Coronary Circulation; Disease Models, Animal; Drug Interactions; Estrogens; Estrogens, Conjugated (USP); Ethinyl Estradiol; Female; Haplorhini; Heart Rate; Lipids; Medroxyprogesterone Acetate; Myocardial Reperfusion Injury; Neovascularization, Physiologic; Norethindrone; Norethindrone Acetate; Ovariectomy; Peroxidase; Progestins; Research Design; Stroke Volume; Vascular Resistance | 2005 |
Natural and synthetic progestins accelerate 7,12-dimethylbenz[a]anthracene-initiated mammary tumors and increase angiogenesis in Sprague-Dawley rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cell Proliferation; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Implants; Immunohistochemistry; Mammary Neoplasms, Experimental; Medroxyprogesterone Acetate; Mifepristone; Neovascularization, Pathologic; Progesterone; Rats; Rats, Sprague-Dawley; Receptors, Progesterone; Time Factors; Vascular Endothelial Growth Factors | 2006 |
Impact of aromatase inhibitors on adhesion formation in a rat model.
Topics: Anastrozole; Animals; Aromatase Inhibitors; Cytokines; Disease Models, Animal; Female; Medroxyprogesterone Acetate; Nitriles; Postoperative Complications; Rats; Rats, Wistar; Receptors, Estrogen; Receptors, Progesterone; Tamoxifen; Tissue Adhesions; Triazoles; Uterine Diseases; Uterus | 2007 |
Medroxyprogesterone acetate prevents the cardioprotective and anti-inflammatory effects of 17beta-estradiol in an in vivo model of myocardial ischemia and reperfusion.
Topics: Animals; Antineoplastic Agents, Hormonal; Blood Pressure; Disease Models, Animal; Drug Interactions; Estradiol; Heart; Heart Rate; Male; Malondialdehyde; Medroxyprogesterone Acetate; Myocardial Infarction; Myocardial Reperfusion Injury; Rabbits; Reperfusion Injury; Troponin I | 2007 |
Efficacy of levamisole on experimental endometriosis.
Topics: Adjuvants, Immunologic; Animals; Contraceptive Agents, Female; Delayed-Action Preparations; Disease Models, Animal; Endometriosis; Female; Fertility Agents, Female; Gonadotropin-Releasing Hormone; Injections, Intramuscular; Injections, Subcutaneous; Leuprolide; Levamisole; Medroxyprogesterone Acetate; Random Allocation; Rats; Rats, Wistar | 2007 |
Neither ovariectomy nor progestin treatment prevents endometrial neoplasia in pten+/- mice.
Topics: Animals; Disease Models, Animal; Endometrial Neoplasms; Female; Genetic Predisposition to Disease; Immunohistochemistry; Male; Medroxyprogesterone Acetate; Mice; Mice, Inbred C57BL; Ovariectomy; PTEN Phosphohydrolase | 2008 |
Medroxyprogesterone acetate modulates the immune response in the uterus, cervix and placenta in a mouse model of preterm birth.
Topics: Animals; Anti-Infective Agents, Local; Cervix Uteri; Cytokines; Disease Models, Animal; Female; Immunity, Cellular; Inflammation; Medroxyprogesterone Acetate; Mice; Placenta; Premature Birth | 2008 |
Murine renal cell carcinoma: a suitable human model.
Topics: Adenocarcinoma; Animals; Diethylstilbestrol; Disease Models, Animal; Female; Humans; Kidney Neoplasms; Kinetics; Male; Medroxyprogesterone; Medroxyprogesterone Acetate; Mice; Mice, Inbred BALB C; Neoplasm Metastasis; Neoplasm Transplantation; Testosterone | 1982 |
Medroxyprogesterone acetate improvement of the hepatic drug-metabolizing enzyme system in rats after chemical liver injury.
Topics: Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Dimethylnitrosamine; Disease Models, Animal; Enzyme Induction; Female; Liver Regeneration; Medroxyprogesterone; Medroxyprogesterone Acetate; Microsomes, Liver; Protein Biosynthesis; Rats; Rats, Inbred Strains | 1983 |
Inhibitory effects of medroxyprogesterone acetate on mouse endometrial carcinogenesis.
Topics: Animals; Anticarcinogenic Agents; Carcinogens; Cocarcinogenesis; Disease Models, Animal; Dose-Response Relationship, Drug; Endometrial Neoplasms; Endometrium; Estradiol; Female; Medroxyprogesterone Acetate; Methylnitrosourea; Mice; Mice, Inbred ICR; Proliferating Cell Nuclear Antigen | 1995 |
A mouse model for studies of mucosal immunity to vaginal infection by herpes simplex virus type 2.
Topics: Animals; B-Lymphocytes; Disease Models, Animal; Estradiol; Estrus; Female; Herpes Genitalis; Herpesvirus 2, Human; Immunity; Medroxyprogesterone Acetate; Mice; Mice, Inbred BALB C; Mucous Membrane; Plasma Cells; Pregnancy; Pregnancy Complications, Infectious; T-Lymphocytes; Vagina | 1994 |
The EnDA endometrial adenocarcinoma: an oestrogen-sensitive, metastasizing, in vivo tumour model of the rat.
Topics: Adenocarcinoma; Animals; Disease Models, Animal; Endometrial Neoplasms; Female; Medroxyprogesterone Acetate; Mice; Mice, Nude; Neoplasm Transplantation; Ovariectomy; Rats; Rats, Inbred Strains; Receptors, Estrogen; Tamoxifen; Transplantation, Isogeneic | 1993 |
SIV transmission. Monkey study prompts high-level public health response.
Topics: Animals; Contraceptive Agents, Female; Disease Models, Animal; Epithelium; Female; Haplorhini; HIV Infections; Humans; Levonorgestrel; Medroxyprogesterone Acetate; Progesterone; Risk Factors; Simian Acquired Immunodeficiency Syndrome; Simian Immunodeficiency Virus; Vagina | 1996 |
Effects on bone of oral hormone replacement therapy initiated 2 years after ovariectomy in young adult monkeys.
Topics: Absorptiometry, Photon; Animals; Biomarkers; Bone Density; Disease Models, Animal; Drug Therapy, Combination; Estrogen Replacement Therapy; Estrogens, Conjugated (USP); Female; Humans; Lumbar Vertebrae; Macaca fascicularis; Medroxyprogesterone Acetate; Osteoporosis, Postmenopausal; Ovariectomy; Progesterone Congeners; Treatment Outcome | 1998 |
Effects of combined sex hormone replacement therapy on small artery biomechanics in pharmacologically ovariectomized rats.
Topics: Animals; Arteries; Biomechanical Phenomena; Disease Models, Animal; Estradiol; Female; Hormone Replacement Therapy; Luteolytic Agents; Medroxyprogesterone Acetate; Ovariectomy; Postmenopause; Rats; Rats, Sprague-Dawley; Triptorelin Pamoate; Vascular Resistance | 2000 |
Histomorphometric aspects of adult castrated rat endometrium after the use of estrogen, progesterone and tamoxifen.
Topics: Animals; Disease Models, Animal; Endometrium; Estrogen Antagonists; Estrogens, Conjugated (USP); Female; Hormone Replacement Therapy; Medroxyprogesterone Acetate; Ovariectomy; Progesterone Congeners; Rats; Rats, Wistar; Tamoxifen | 2000 |
Five novel hormone-responsive cell lines derived from murine mammary ductal carcinomas: in vivo and in vitro effects of estrogens and progestins.
Topics: Animals; Carcinoma, Ductal, Breast; Cell Differentiation; Cell Division; Disease Models, Animal; Estradiol; Female; Immunohistochemistry; Mammary Neoplasms, Experimental; Medroxyprogesterone Acetate; Mice; Mice, Inbred BALB C; Microscopy, Electron; Neoplasm Transplantation; Neoplasms, Hormone-Dependent; Receptor, ErbB-2; Receptors, Estrogen; Receptors, Progesterone; Tumor Cells, Cultured | 2001 |
Effects of prolonged administration of the 19-nor-testosterone derivatives norethindrone and norgestrel to female NZB/W mice: comparison with medroxyprogesterone and ethinyl estradiol.
Topics: Animals; Antibodies, Antinuclear; Contraceptives, Oral, Hormonal; Disease Models, Animal; Ethinyl Estradiol; Female; Longevity; Lupus Erythematosus, Systemic; Lupus Nephritis; Medroxyprogesterone Acetate; Mice; Mice, Inbred NZB; Norethindrone; Norgestrel; Time Factors; Urinary Tract | 1991 |
DMPA and breast cancer: the dog has had its day.
Topics: Adult; Animals; Breast Neoplasms; Contraceptive Agents, Female; Developing Countries; Disease Models, Animal; Dogs; Female; Humans; Medroxyprogesterone; Medroxyprogesterone Acetate; Product Surveillance, Postmarketing | 1991 |
Medroxyprogesterone acetate induces diabetes insipidus in Chinese hamsters.
Topics: Animals; Arginine Vasopressin; Cricetinae; Cricetulus; Diabetes Insipidus; Disease Models, Animal; Female; Kidney Concentrating Ability; Male; Medroxyprogesterone; Medroxyprogesterone Acetate; Polyuria; Sex Factors; Species Specificity; Vasopressins; Water Deprivation | 1986 |
Effect of medroxyprogesterone acetate on peritoneal adhesion.
Topics: Animals; Disease Models, Animal; Female; Immunosuppressive Agents; Medroxyprogesterone; Medroxyprogesterone Acetate; Peritoneal Diseases; Rabbits; Tissue Adhesions | 1988 |