Page last updated: 2024-08-17

medroxyprogesterone acetate and Cachexia

medroxyprogesterone acetate has been researched along with Cachexia in 16 studies

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's9 (56.25)18.2507
2000's6 (37.50)29.6817
2010's1 (6.25)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Macciò, A; Madeddu, C; Mantovani, G; Panzone, F; Tanca, FM1
Chen, SZ; Zhang, YL1
Antonietti, C; Gilli, G; Lelli, G; Montanari, M; Scapoli, D1
Cerchietti, LC; Diament, MJ; Klein, SM; Navigante, A; Peluffo, GD; Ranuncolo, SM; Stillitani, I1
Contu, P; Deiana, L; Dessì, M; Floris, C; Gramignano, G; Macciò, A; Madeddu, C; Mantovani, G; Massa, E; Panzone, F; Sanna, E; Serpe, R; Tanca, FM1
Baccino, FM; Costelli, P; Tessitore, L1
Allbright, A; Downer, S; Joel, S; Plant, H; Slevin, M; Stubbs, L; Talbot, D1
Fournier, F; Livrozet, JM; Rambeaud, B; Saint-Marc, T; Touraine, JL1
Del Giacco, S; Dessì, D; Esu, S; Lai, P; Macciò, A; Mantovani, G; Massa, E; Melis, G; Santona, MC1
Del Giacco, GS; Dessì, D; Esu, S; Lai, P; Macciò, A; Mantovani, G; Massa, E; Melis, GB; Santona, MC1
Hoefnagels, JM; Schols, AM; Simons, JP; ten Velde, GP; Westerterp, KR; Wouters, EF1
Ghiani, M; Lai, P; Macciò, A; Mantovani, G; Massa, E; Santona, MC2
Kurebayashi, J; Otsuki, T; Sonoo, H; Yamamoto, S1
Ogawa, M; Yamashita, JI1
Mantovani, G1

Reviews

5 review(s) available for medroxyprogesterone acetate and Cachexia

ArticleYear
Medroxyprogesterone acetate in the management of cancer cachexia.
    Expert opinion on pharmacotherapy, 2009, Volume: 10, Issue:8

    Topics: Animals; Cachexia; Humans; Medroxyprogesterone Acetate; Neoplasms

2009
Treatment of the cancer anorexia-cachexia syndrome: a critical reappraisal.
    Journal of chemotherapy (Florence, Italy), 2003, Volume: 15, Issue:3

    Topics: Anorexia; Cachexia; Clinical Trials as Topic; Drug Therapy, Combination; Female; Humans; Male; Medroxyprogesterone Acetate; Megestrol Acetate; Metoclopramide; Neoplasms; Prognosis; Risk Assessment; Severity of Illness Index; Survival Analysis; Terminally Ill; Treatment Outcome; Wasting Syndrome

2003
Cytokine activity in cancer-related anorexia/cachexia: role of megestrol acetate and medroxyprogesterone acetate.
    Seminars in oncology, 1998, Volume: 25, Issue:2 Suppl 6

    Topics: Anorexia; Appetite Stimulants; Cachexia; Cytokines; Humans; Interleukin-1; Interleukin-6; Medroxyprogesterone Acetate; Megestrol Acetate; Neoplasms; Progesterone Congeners; Tumor Necrosis Factor-alpha; Wasting Syndrome

1998
Cytokine involvement in cancer anorexia/cachexia: role of megestrol acetate and medroxyprogesterone acetate on cytokine downregulation and improvement of clinical symptoms.
    Critical reviews in oncogenesis, 1998, Volume: 9, Issue:2

    Topics: Anorexia; Antineoplastic Agents; Appetite Stimulants; Cachexia; Clinical Trials as Topic; Cytokines; Humans; Medroxyprogesterone Acetate; Megestrol Acetate; Neoplasm Proteins; Neoplasms; Progesterone Congeners; Serotonin

1998
Medroxyprogesterone acetate and cancer cachexia: interleukin-6 involvement.
    Breast cancer (Tokyo, Japan), 2000, Volume: 7, Issue:2

    Topics: Cachexia; Female; Humans; Interleukin-6; Medroxyprogesterone Acetate; Neoplasms

2000

Trials

3 trial(s) available for medroxyprogesterone acetate and Cachexia

ArticleYear
Randomized phase III clinical trial of five different arms of treatment for patients with cancer cachexia: interim results.
    Nutrition (Burbank, Los Angeles County, Calif.), 2008, Volume: 24, Issue:4

    Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Hormonal; Antioxidants; Appetite Stimulants; Ascorbic Acid; Basal Metabolism; Cachexia; Carnitine; Dietary Supplements; Exercise; Fatigue; Female; Humans; Interleukin-6; Male; Medroxyprogesterone Acetate; Megestrol Acetate; Middle Aged; Muscle Proteins; Neoplasms; Nutritional Support; Oxidative Stress; Treatment Outcome; Tumor Necrosis Factor-alpha; Vitamin A; Vitamin E

2008
A double blind placebo controlled trial of medroxyprogesterone acetate (MPA) in cancer cachexia.
    British journal of cancer, 1993, Volume: 67, Issue:5

    Topics: Appetite; Cachexia; Double-Blind Method; Humans; Medroxyprogesterone Acetate; Middle Aged; Neoplasms; Prealbumin; Retinol-Binding Proteins

1993
Effects of medroxyprogesterone acetate on food intake, body composition, and resting energy expenditure in patients with advanced, nonhormone-sensitive cancer: a randomized, placebo-controlled trial.
    Cancer, 1998, Feb-01, Volume: 82, Issue:3

    Topics: Aged; Appetite; Body Composition; Cachexia; Double-Blind Method; Eating; Energy Metabolism; Female; Humans; Male; Medroxyprogesterone Acetate; Neoplasms; Progesterone Congeners; Weight Loss

1998

Other Studies

8 other study(ies) available for medroxyprogesterone acetate and Cachexia

ArticleYear
Treatment of cancer cachexia in mice by combination of dsRNA-dependent protein kinase inhibitor and medroxyprogesterone acetate.
    Oncology reports, 2012, Volume: 27, Issue:2

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Blood Glucose; Body Weight; Cachexia; Cytokines; Disease Models, Animal; eIF-2 Kinase; Humans; Male; Medroxyprogesterone Acetate; Mice; Mice, Inbred BALB C; Muscle, Skeletal; Neoplasms; Protein Kinase Inhibitors; Tumor Burden

2012
Inhibition of tumor progression and paraneoplastic syndrome development in a murine lung adenocarcinoma by medroxyprogesterone acetate and indomethacin.
    Cancer investigation, 2006, Volume: 24, Issue:2

    Topics: Adenocarcinoma; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Appetite Stimulants; Cachexia; Enzyme-Linked Immunosorbent Assay; Female; Hypercalcemia; Indomethacin; Interleukin-1; Interleukin-6; Lung Neoplasms; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Medroxyprogesterone Acetate; Mice; Mice, Inbred BALB C; Paraneoplastic Syndromes

2006
Pharmacological interference with tissue hypercatabolism in tumour-bearing rats.
    The Biochemical journal, 1994, Apr-01, Volume: 299 ( Pt 1)

    Topics: Adrenalectomy; Animals; Aspirin; Blood Glucose; Body Weight; Cachexia; Cathepsin D; Cholesterol; Endopeptidases; Hormones; Insulin; Leupeptins; Male; Medroxyprogesterone Acetate; Muscle Proteins; Neoplasm Transplantation; Neoplasms, Experimental; Rats; Rats, Wistar; Triglycerides

1994
[Value of acetate medroxyprogesterone in the treatment of cachexia in AIDS].
    Presse medicale (Paris, France : 1983), 1993, Apr-03, Volume: 22, Issue:12

    Topics: Acquired Immunodeficiency Syndrome; Adult; Cachexia; Humans; Medroxyprogesterone Acetate

1993
Medroxyprogesterone acetate reduces the production of cytokines and serotonin involved in anorexia/cachexia and emesis by peripheral blood mononuclear cells of cancer patients.
    Biochemical Society transactions, 1997, Volume: 25, Issue:2

    Topics: Anorexia; Antigens, CD; Cachexia; Cells, Cultured; Cytokines; Enzyme-Linked Immunosorbent Assay; Female; Humans; Interleukins; Lymphocyte Activation; Lymphocytes; Medroxyprogesterone Acetate; Neoplasms; Receptors, Interleukin-2; Serotonin; Tumor Necrosis Factor-alpha; Vomiting

1997
Medroxyprogesterone acetate reduces the in vitro production of cytokines and serotonin involved in anorexia/cachexia and emesis by peripheral blood mononuclear cells of cancer patients.
    European journal of cancer (Oxford, England : 1990), 1997, Volume: 33, Issue:4

    Topics: Aged; Anorexia; Antineoplastic Agents, Hormonal; Cachexia; Cell Division; Cells, Cultured; Cytokines; Female; Humans; Interleukin-1; Interleukin-2; Interleukin-6; Leukocytes, Mononuclear; Male; Medroxyprogesterone Acetate; Middle Aged; Neoplasms; Receptors, Interleukin-2; Serotonin; Tumor Necrosis Factor-alpha; Vomiting

1997
Medroxyprogesterone acetate inhibits interleukin 6 secretion from KPL-4 human breast cancer cells both in vitro and in vivo: a possible mechanism of the anticachectic effect.
    British journal of cancer, 1999, Volume: 79, Issue:3-4

    Topics: Animals; Antineoplastic Agents, Hormonal; Body Weight; Breast Neoplasms; Cachexia; Female; Humans; Injections, Intramuscular; Interleukin-6; Medroxyprogesterone Acetate; Mice; Mice, Nude; Neoplasm Transplantation; Tumor Cells, Cultured

1999
Cachexia and anorexia.
    Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2000, Volume: 8, Issue:6

    Topics: Anorexia; Cachexia; Cytokines; Humans; Medroxyprogesterone Acetate; Megestrol Acetate; Neoplasms; Progesterone Congeners

2000