Page last updated: 2024-08-17

medroxyprogesterone acetate and Bone Fractures

medroxyprogesterone acetate has been researched along with Bone Fractures in 39 studies

Research

Studies (39)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	1 (2.56)	18.2507
2000's	21 (53.85)	29.6817
2010's	15 (38.46)	24.3611
2020's	2 (5.13)	2.80

Authors

Authors	Studies
Alexeeff, S; Armstrong, MA; Chandra, M; Lo, JC; Raine-Bennett, T	1
Vestergaard, P	1
Anderson, GL; Aragaki, AK; Banack, H; Chlebowski, RT; Gass, M; Manson, JE; Prentice, RL; Qi, L; Rossouw, JE; Shadyab, AH; Snively, BM; Wallace, R; Zhao, S	1
Crandall, CJ; Handelman, SK; Hovey, KM; Jackson, RD; Nassir, R; Nie, J; Ochs-Balcom, HM; Preus, L; Sucheston-Campbell, LE; Wactawski-Wende, J; Wang, Y	1
Arena, PL; Ataher, Q; Bone, HG; Harel, Z; Kaunitz, AM; Lanza, LL; McQuay, LJ; Ross, D; Rothman, KJ; Wolter, KD	2
Gurney, EP; Nachtigall, LE; Nachtigall, MJ; Naftolin, F	1
Chen, M; Curtis, KM; Grimes, DA; Lopez, LM; Schulz, KF	1
Chen, M; Curtis, KM; Helmerhorst, FM; Lopez, LM; Mullins Long, S	1
Mosekilde, L; Rejnmark, L; Vestergaard, P	1
Bérubé, J; Brown, JP; Charbonneau, L; Francoeur, D; Gilbert, A; Gilbert, F; Guilbert, ER; Jacob, R; Kaunitz, AM; Morin, R; Roy, G; Senikas, V; Wagner, MS	1
Curtis, KM; Grimes, DA; Lopez, LM; Schulz, KF	3
Allison, M; Anderson, GL; Brzyski, R; Jackson, RD; Johnson, KC; Kuller, LH; Lane, DS; Langer, RD; Manson, JE; Ockene, J; Pettinger, M; Prentice, RL; Rossouw, JE; Sarto, G; Wactawski-Wende, J	1
Brauchli, YB; Jick, SS; Kraenzlin, ME; Meier, C; Meier, CR	1
Davidge Pitts, CJ; Kearns, AE	1
Grimes, DA; Kaunitz, AM	1
Bahamondes, L; Bahamondes, MV; Castro, S; Fernandes, A; Viola, AS; Viola, CF	1
Dorale, A; Feldman, HA; Gordon, CM; Pitts, SA	1
Chen, M; Curtis, KM; Helmerhorst, FM; Lopez, LM; Mullins, S	1
Anderson, GL; Beresford, SA; Howard, BV; Jackson, RD; Johnson, KC; Kooperberg, C; Kotchen, JM; LaCroix, AZ; Ockene, J; Prentice, RL; Rossouw, JE; Stefanick, ML	1
Enserink, M	1
Chen, F; de Lignieres, B; Lin, S; Qin, M; Sun, A; Wei, Y; Yu, W; Zhang, Y	1
Sagraves, R	1
Binder, EF; Brown, M; Kohrt, WM; Sinacore, DR; Villareal, DT; Williams, DB; Yarasheski, KE	1
Cauley, JA; Chen, Z; Cummings, SR; Jackson, RD; LaCroix, AZ; LeBoff, M; Lewis, CE; McGowan, J; Neuner, J; Pettinger, M; Robbins, J; Stefanick, ML; Wactawski-Wende, J; Watts, NB	1
Heinemann, V; Parhofer, K	1
Lindsay, R	1
Albertazzi, P; Bottazzi, M; Steel, SA	1
Berenson, A; Clark, MK; Cromer, BA; Cundy, T; Kaunitz, AM; Scholes, D	1
Ichikawa, L; LaCroix, AZ; Ott, SM; Scholes, D; Wetmore, CM	1
Arias, R; Kaunitz, AM; McClung, M	1
Ott, SM	1
Groh, KW; Stevermer, JJ	1
Barrett-Connor, E; Cauley, J; Furberg, C; Grady, D; Haskell, W; Hulley, S; Hunninghake, D; Knopp, R; Lowery, M; Satterfield, S; Schrott, H; Vittinghoff, E	1

Reviews

12 review(s) available for medroxyprogesterone acetate and Bone Fractures

Article	Year
Drugs Causing Bone Loss. Handbook of experimental pharmacology, 2020, Volume: 262 Topics: Bone and Bones; Bone Density; Fractures, Bone; Humans; Medroxyprogesterone Acetate; Pharmaceutical Preparations	2020
The Women's Health Initiative trial and related studies: 10 years later: a clinician's view. The Journal of steroid biochemistry and molecular biology, 2014, Volume: 142 Topics: Aged; Atherosclerosis; Breast Neoplasms; Calcium; Cognition; Coronary Disease; Estrogen Replacement Therapy; Estrogens, Conjugated (USP); Female; Fractures, Bone; Humans; Medroxyprogesterone Acetate; Middle Aged; Postmenopause; Progestins; Randomized Controlled Trials as Topic; Risk Assessment; Stroke; Testosterone; Venous Thromboembolism; Vitamin D; Women's Health	2014
Steroidal contraceptives: effect on bone fractures in women. The Cochrane database of systematic reviews, 2014, Jun-24, Issue:6 Topics: Bone Density; Bone Remodeling; Contraceptives, Oral, Hormonal; Estrogens; Female; Fractures, Bone; Humans; Medroxyprogesterone Acetate; Premenopause; Progestins; Randomized Controlled Trials as Topic	2014
Steroidal contraceptives and bone fractures in women: evidence from observational studies. The Cochrane database of systematic reviews, 2015, Jul-21, Issue:7 Topics: Age Factors; Case-Control Studies; Cohort Studies; Contraceptives, Oral, Hormonal; Female; Fractures, Bone; Humans; Intrauterine Devices, Medicated; Medroxyprogesterone Acetate; Observational Studies as Topic; Progestins; Time Factors	2015
The use of depot-medroxyprogesterone acetate in contraception and its potential impact on skeletal health. Contraception, 2009, Volume: 79, Issue:3 Topics: Bone Density; Canada; Contraception; Contraceptive Agents, Female; Delayed-Action Preparations; Female; Fractures, Bone; Humans; Medroxyprogesterone Acetate; Osteoporosis; Pregnancy; Pregnancy Rate	2009
Steroidal contraceptives: effect on bone fractures in women. The Cochrane database of systematic reviews, 2009, Apr-15, Issue:2 Topics: Bone Density; Bone Remodeling; Contraceptives, Oral, Hormonal; Estrogens; Female; Fractures, Bone; Humans; Medroxyprogesterone Acetate; Premenopause; Progestins; Randomized Controlled Trials as Topic	2009
Update on medications with adverse skeletal effects. Mayo Clinic proceedings, 2011, Volume: 86, Issue:4 Topics: Animals; Aromatase Inhibitors; Bone and Bones; Bone Density; Breast Neoplasms; Contraceptive Agents, Female; Diphosphonates; Fractures, Bone; Glucocorticoids; Gonadotropin-Releasing Hormone; Humans; Medroxyprogesterone Acetate; Osteoporosis; Peroxisome Proliferator-Activated Receptors; Proton Pump Inhibitors; Selective Serotonin Reuptake Inhibitors; Thiazolidinediones	2011
Steroidal contraceptives: effect on bone fractures in women. The Cochrane database of systematic reviews, 2011, Jul-06, Issue:7 Topics: Bone Density; Bone Remodeling; Contraceptives, Oral, Hormonal; Estrogens; Female; Fractures, Bone; Humans; Medroxyprogesterone Acetate; Premenopause; Progestins; Randomized Controlled Trials as Topic	2011
Steroidal contraceptives and bone fractures in women: evidence from observational studies. The Cochrane database of systematic reviews, 2012, Aug-15, Issue:8 Topics: Age Factors; Case-Control Studies; Cohort Studies; Contraceptives, Oral, Hormonal; Female; Fractures, Bone; Humans; Intrauterine Devices, Medicated; Medroxyprogesterone Acetate; Progestins; Time Factors	2012
Hormones and bone health in postmenopausal women. Endocrine, 2004, Volume: 24, Issue:3 Topics: Aged; Bone and Bones; Bone Density; Clinical Trials as Topic; Dose-Response Relationship, Drug; Estrogen Replacement Therapy; Estrogens; Estrogens, Conjugated (USP); Female; Fractures, Bone; Humans; Medroxyprogesterone Acetate; Middle Aged; Osteoporosis, Postmenopausal; Postmenopause; Women's Health	2004
Steroidal contraceptives: effect on bone fractures in women. The Cochrane database of systematic reviews, 2006, Oct-18, Issue:4 Topics: Bone Density; Contraceptive Agents, Female; Estrogens; Female; Fractures, Bone; Humans; Medroxyprogesterone Acetate; Progestins; Randomized Controlled Trials as Topic	2006
Bone density recovery after depot medroxyprogesterone acetate injectable contraception use. Contraception, 2008, Volume: 77, Issue:2 Topics: Bone Density; Bone Resorption; Contraceptive Agents, Female; Female; Fractures, Bone; Humans; Medroxyprogesterone Acetate; Postmenopause; Risk Factors; Time Factors	2008

Trials

9 trial(s) available for medroxyprogesterone acetate and Bone Fractures

Article	Year
Benefits and risks of postmenopausal hormone therapy when it is initiated soon after menopause. American journal of epidemiology, 2009, Jul-01, Volume: 170, Issue:1 Topics: Aged; Breast Neoplasms; Colorectal Neoplasms; Contraceptive Agents, Female; Coronary Disease; Endometrial Neoplasms; Estrogen Replacement Therapy; Estrogens; Estrogens, Conjugated (USP); Female; Follow-Up Studies; Fractures, Bone; Humans; Incidence; Medroxyprogesterone Acetate; Menopause; Middle Aged; Postmenopause; Progestins; Pulmonary Embolism; Retrospective Studies; Risk Factors; Stroke; Survival Rate; Thrombosis; Time Factors; Washington	2009
Risks and benefits of estrogen plus progestin in healthy postmenopausal women: principal results From the Women's Health Initiative randomized controlled trial. JAMA, 2002, Jul-17, Volume: 288, Issue:3 Topics: Aged; Breast Neoplasms; Clinical Trials Data Monitoring Committees; Colorectal Neoplasms; Coronary Disease; Endometrial Neoplasms; Estrogen Replacement Therapy; Estrogens, Conjugated (USP); Female; Fractures, Bone; Humans; Medroxyprogesterone Acetate; Middle Aged; Myocardial Infarction; Postmenopause; Progesterone Congeners; Proportional Hazards Models; Pulmonary Embolism; Risk; Stroke; Survival Analysis; Thrombosis; Treatment Outcome	2002
Percutaneous estrogen in prevention of early postmenopausal bone loss in Chinese women. Chinese medical journal, 2002, Volume: 115, Issue:12 Topics: Administration, Cutaneous; Adult; Bone Density; Estradiol; Estrogen Replacement Therapy; Female; Fractures, Bone; Humans; Medroxyprogesterone Acetate; Middle Aged; Osteoporosis, Postmenopausal	2002
Effects of exercise training added to ongoing hormone replacement therapy on bone mineral density in frail elderly women. Journal of the American Geriatrics Society, 2003, Volume: 51, Issue:7 Topics: Aged; Aged, 80 and over; Body Composition; Bone Density; Combined Modality Therapy; Estrogen Replacement Therapy; Estrogens, Conjugated (USP); Exercise Therapy; Female; Fractures, Bone; Frail Elderly; Humans; Medroxyprogesterone Acetate; Osteoporosis, Postmenopausal; Progesterone Congeners; Prospective Studies	2003
Effects of estrogen plus progestin on risk of fracture and bone mineral density: the Women's Health Initiative randomized trial. JAMA, 2003, Oct-01, Volume: 290, Issue:13 Topics: Aged; Bone Density; Double-Blind Method; Estrogen Replacement Therapy; Estrogens, Conjugated (USP); Female; Fractures, Bone; Humans; Medroxyprogesterone Acetate; Middle Aged; Osteoporosis; Postmenopause; Progesterone Congeners; Proportional Hazards Models; Risk	2003
[Risk and benefits of hormone replacement therapy by postmenopausal women. WHI-Study]. Der Internist, 2003, Volume: 44, Issue:7 Topics: Aged; Breast Neoplasms; Colorectal Neoplasms; Coronary Disease; Endometrial Neoplasms; Estrogen Replacement Therapy; Estrogens, Conjugated (USP); Female; Fractures, Bone; Hormone Replacement Therapy; Humans; Incidence; Medroxyprogesterone Acetate; Middle Aged; Myocardial Infarction; Postmenopause; Progesterone Congeners; Proportional Hazards Models; Pulmonary Embolism; Risk Assessment; Stroke; Survival Analysis; Thrombosis; Treatment Outcome; United States; Women's Health	2003
Association between caffeine intake and bone mass among young women: potential effect modification by depot medroxyprogesterone acetate use. Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 2008, Volume: 19, Issue:4 Topics: Absorptiometry, Photon; Adolescent; Adult; Bone Density; Caffeine; Central Nervous System Stimulants; Contraceptive Agents, Female; Female; Fractures, Bone; Humans; Longitudinal Studies; Medroxyprogesterone Acetate; Osteoporosis, Postmenopausal; Treatment Outcome	2008
Effects of hormone therapy on bone mineral density: results from the postmenopausal estrogen/progestin interventions (PEPI) trial. The Writing Group for the PEPI. JAMA, 1996, Nov-06, Volume: 276, Issue:17 Topics: Absorptiometry, Photon; Bone Density; Double-Blind Method; Estrogen Replacement Therapy; Estrogens, Conjugated (USP); Female; Fractures, Bone; Hip; Humans; Medroxyprogesterone Acetate; Middle Aged; Postmenopause; Progesterone; Progesterone Congeners; Spine; Statistics as Topic	1996
Noncardiovascular disease outcomes during 6.8 years of hormone therapy: Heart and Estrogen/progestin Replacement Study follow-up (HERS II). JAMA, 2002, Jul-03, Volume: 288, Issue:1 Topics: Aged; Biliary Tract Diseases; Biliary Tract Surgical Procedures; Cause of Death; Coronary Disease; Estrogen Replacement Therapy; Estrogens, Conjugated (USP); Female; Follow-Up Studies; Fractures, Bone; Humans; Medroxyprogesterone Acetate; Neoplasms; Postmenopause; Pulmonary Embolism; Risk Factors; Survival Analysis; Thromboembolism; Treatment Outcome; Venous Thrombosis	2002

Other Studies

18 other study(ies) available for medroxyprogesterone acetate and Bone Fractures

Article	Year
Depot Medroxyprogesterone Acetate, Oral Contraceptive, Intrauterine Device Use, and Fracture Risk. Obstetrics and gynecology, 2019, Volume: 134, Issue:3 Topics: Adolescent; Adult; Child; Contraceptive Agents, Female; Contraceptives, Oral; Female; Fractures, Bone; Humans; Intrauterine Devices, Medicated; Levonorgestrel; Medroxyprogesterone Acetate; Middle Aged; Progestins; Retrospective Studies; Risk Factors; Young Adult	2019
Dual-Outcome Intention-to-Treat Analyses in the Women's Health Initiative Randomized Controlled Hormone Therapy Trials. American journal of epidemiology, 2020, 09-01, Volume: 189, Issue:9 Topics: Aged; Cardiovascular Diseases; Estrogen Replacement Therapy; Estrogens, Conjugated (USP); Female; Fractures, Bone; Gallbladder Diseases; Humans; Incidence; Intention to Treat Analysis; Medroxyprogesterone Acetate; Middle Aged; Postmenopause; Randomized Controlled Trials as Topic; Risk Factors; United States	2020
Gene-Hormone Therapy Interaction and Fracture Risk in Postmenopausal Women. The Journal of clinical endocrinology and metabolism, 2017, 06-01, Volume: 102, Issue:6 Topics: Aged; Bone Density; Contraceptive Agents, Female; Estrogen Replacement Therapy; Estrogens; Estrogens, Conjugated (USP); Female; Fractures, Bone; Gene-Environment Interaction; Genetic Predisposition to Disease; Genotype; Humans; Incidence; Medroxyprogesterone Acetate; Middle Aged; Proportional Hazards Models; United States; White People	2017
Use of depot medroxyprogesterone acetate contraception and incidence of bone fracture. Obstetrics and gynecology, 2013, Volume: 121, Issue:3 Topics: Adolescent; Adult; Contraceptive Agents, Female; Delayed-Action Preparations; Female; Fractures, Bone; Humans; Incidence; Medroxyprogesterone Acetate; Middle Aged; Retrospective Studies; United Kingdom; Young Adult	2013
Comment on journal review of 'Use of depot medroxyprogesterone acetate contraception and incidence of bone fracture'. The journal of family planning and reproductive health care, 2013, Volume: 39, Issue:4 Topics: Contraceptive Agents, Female; Female; Fractures, Bone; Humans; Incidence; Medroxyprogesterone Acetate	2013
Committee Opinion No. 602: Depot medroxyprogesterone acetate and bone effects. Obstetrics and gynecology, 2014, Volume: 123, Issue:6 Topics: Adolescent; Adult; Bone and Bones; Bone Density; Contraceptive Agents, Female; Counseling; Delayed-Action Preparations; Drug Labeling; Female; Fractures, Bone; Humans; Medroxyprogesterone Acetate; Pregnancy; Risk Assessment; Young Adult	2014
ACOG Committee Opinion No. 415: Depot medroxyprogesterone acetate and bone effects. Obstetrics and gynecology, 2008, Volume: 112, Issue:3 Topics: Bone Density; Contraceptive Agents, Female; Drug Approval; Female; Fractures, Bone; Humans; Medroxyprogesterone Acetate; Osteoporosis; Time Factors	2008
The effects of depot medroxyprogesterone acetate and intrauterine device use on fracture risk in Danish women. Contraception, 2008, Volume: 78, Issue:6 Topics: Body Mass Index; Case-Control Studies; Confidence Intervals; Confounding Factors, Epidemiologic; Delayed-Action Preparations; Denmark; Female; Fractures, Bone; Humans; Intrauterine Devices, Medicated; Life Style; Medroxyprogesterone Acetate; Middle Aged; Odds Ratio; Registries; Risk Assessment; Time Factors	2008
Use of depot medroxyprogesterone acetate and fracture risk. The Journal of clinical endocrinology and metabolism, 2010, Volume: 95, Issue:11 Topics: Adult; Bone Density; Contraceptive Agents, Female; Female; Fractures, Bone; Humans; Incidence; Medroxyprogesterone Acetate; Odds Ratio; Risk	2010
Removing the black box warning for depot medroxyprogesterone acetate. Contraception, 2011, Volume: 84, Issue:3 Topics: Bone Density; Contraceptive Agents, Female; Drug Labeling; Drug Utilization; Female; Fractures, Bone; Humans; Intrauterine Devices, Medicated; Medroxyprogesterone Acetate; Postmenopause; Practice Patterns, Physicians'; Pregnancy; Prescriptions	2011
A cross-sectional study of the forearm bone mineral density in long-term current users of the injectable contraceptive depot medroxyprogesterone acetate. Contraception, 2011, Volume: 84, Issue:5 Topics: Absorptiometry, Photon; Adult; Bone Density; Brazil; Contraceptive Agents, Female; Copper; Cross-Sectional Studies; Delayed-Action Preparations; Female; Forearm; Fractures, Bone; Humans; Intrauterine Devices, Medicated; Medroxyprogesterone Acetate; Middle Aged; Time Factors; Young Adult	2011
Bone mineral density, fracture, and vitamin D in adolescents and young women using depot medroxyprogesterone acetate. Journal of pediatric and adolescent gynecology, 2012, Volume: 25, Issue:1 Topics: Absorptiometry, Photon; Adolescent; Bone Density; Boston; Contraceptive Agents, Female; Female; Fractures, Bone; Humans; Medroxyprogesterone Acetate; Retrospective Studies; Risk Factors; Statistics, Nonparametric; Vitamin D; Young Adult	2012
Women's health. The vanishing promises of hormone replacement. Science (New York, N.Y.), 2002, Jul-19, Volume: 297, Issue:5580 Topics: Breast Neoplasms; Cardiovascular Diseases; Colorectal Neoplasms; Estrogen Replacement Therapy; Estrogens, Conjugated (USP); Female; Fractures, Bone; Humans; Medroxyprogesterone Acetate; Menopause; Postmenopause; Pulmonary Embolism; Randomized Controlled Trials as Topic; Risk Factors; Selection Bias; Time Factors	2002
Evaluating therapeutic modalities for prevention and treatment of postmenopausal osteoporosis. The Annals of pharmacotherapy, 2003, Volume: 37, Issue:5 Topics: Dietary Supplements; Estrogens; Female; Fractures, Bone; Hormone Replacement Therapy; Humans; Medroxyprogesterone Acetate; National Institutes of Health (U.S.); Osteoporosis, Postmenopausal; Progesterone Congeners; United States; Women's Health	2003
Bone mineral density and depot medroxyprogesterone acetate. Contraception, 2006, Volume: 73, Issue:6 Topics: Adult; Body Mass Index; Bone Density; Calcium, Dietary; Contraceptives, Oral, Combined; Cross-Sectional Studies; Delayed-Action Preparations; Female; Femur Neck; Fractures, Bone; Humans; Medroxyprogesterone Acetate; Middle Aged; Osteoporosis, Postmenopausal; Risk; Spine	2006
Depot medroxyprogesterone acetate and bone mineral density in adolescents--the Black Box Warning: a Position Paper of the Society for Adolescent Medicine. The Journal of adolescent health : official publication of the Society for Adolescent Medicine, 2006, Volume: 39, Issue:2 Topics: Adolescent; Adolescent Medicine; Bone Density; Bone Resorption; Calcium, Dietary; Contraceptive Agents, Female; Contraindications; Counseling; Delayed-Action Preparations; Drug Labeling; Female; Fractures, Bone; Humans; Medroxyprogesterone Acetate; Societies, Medical; United States; United States Food and Drug Administration	2006
Reproductive hormones and skeletal health in young women. The Journal of clinical endocrinology and metabolism, 2008, Volume: 93, Issue:4 Topics: Bone Density; Estrogens; Female; Fractures, Bone; Humans; Lactation; Medroxyprogesterone Acetate; Pregnancy	2008
Does estrogen/progestin therapy in post-menopausal women decrease their risk of fracture? The Journal of family practice, 2001, Volume: 50, Issue:11 Topics: Age Factors; Aged; Estrogen Replacement Therapy; Estrogens, Conjugated (USP); Evidence-Based Medicine; Female; Fractures, Bone; Humans; Medroxyprogesterone Acetate; Middle Aged; Osteoporosis, Postmenopausal; Postmenopause; Progesterone Congeners; Risk Factors; Time Factors; Treatment Outcome	2001