medrogestone and Myocardial-Infarction

Side effects, especially cardiovascular, of oral contraception in healthy women are discussed. A causal relationship between ovulation inhibitors and thromboembolic disease has been demon demonstrated epidemiologically and experimentally. Thrombus formation may be due to disturbances of blood coagulation, lesions, of the vascular wall, or blood flow disorders; the "pill" influences all 3 components. The role of the "pill" in the etiology of hypertension has not been explained, but there is no doubt of its existence. Although the risk to a healthy woman with no predisposing factors is small, it is real, and must be considered by the patient and her physician.

Topics: Cerebrovascular Disorders; Contraceptives, Oral; Contraceptives, Oral, Hormonal; Estrogens; Female; Humans; Medrogestone; Myocardial Infarction; Thromboembolism